JP2016540505A - アデノウイルス発現免疫細胞刺激受容体アゴニスト - Google Patents

アデノウイルス発現免疫細胞刺激受容体アゴニスト Download PDF

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JP2016540505A
JP2016540505A JP2016533143A JP2016533143A JP2016540505A JP 2016540505 A JP2016540505 A JP 2016540505A JP 2016533143 A JP2016533143 A JP 2016533143A JP 2016533143 A JP2016533143 A JP 2016533143A JP 2016540505 A JP2016540505 A JP 2016540505A
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adenovirus
cells
cancer
replication competent
tumor
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フランク トゥファロ，
フランク トゥファロ，
フアン フエヨ−マルガレト，
フアン フエヨ−マルガレト，
カンデラリア ゴメス−マンサノ，
カンデラリア ゴメス−マンサノ，
チャールズ コンラッド，
チャールズ コンラッド，
ダブリュー．ケー． アルフレッド ユン，
ダブリュー．ケー． アルフレッド ユン，
ホン ジアン，
ホン ジアン，
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University of Texas System
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/217—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2016533143A 2013-11-22 2014-11-21 アデノウイルス発現免疫細胞刺激受容体アゴニスト Withdrawn JP2016540505A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361907860P 2013-11-22 2013-11-22
US61/907,860 2013-11-22
PCT/US2014/066920 WO2015077624A1 (en) 2013-11-22 2014-11-21 Adenovirus expressing immune cell stimulatory receptor agonist(s)

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JP2016540505A true JP2016540505A (ja) 2016-12-28
JP2016540505A5 JP2016540505A5 (https=) 2017-12-28

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JP2019238013A Pending JP2020048582A (ja) 2013-11-22 2019-12-27 アデノウイルス発現免疫細胞刺激受容体アゴニスト
JP2021097883A Pending JP2021137029A (ja) 2013-11-22 2021-06-11 アデノウイルス発現免疫細胞刺激受容体アゴニスト

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JP2021097883A Pending JP2021137029A (ja) 2013-11-22 2021-06-11 アデノウイルス発現免疫細胞刺激受容体アゴニスト

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US (4) US20160289645A1 (https=)
EP (2) EP3071697B1 (https=)
JP (3) JP2016540505A (https=)
KR (1) KR20160137946A (https=)
CN (2) CN114317461A (https=)
AU (1) AU2014352749A1 (https=)
CA (1) CA2931322A1 (https=)
DK (1) DK3071697T3 (https=)
ES (1) ES2765489T3 (https=)
SG (1) SG10201907841UA (https=)
WO (1) WO2015077624A1 (https=)

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JP2020528890A (ja) * 2017-07-21 2020-10-01 シァメン・ユニヴァーシティ 腫瘍を治療するためのウイルス
JP2022501339A (ja) * 2018-09-15 2022-01-06 メモリアル スローン ケタリング キャンサー センター がん免疫療法のための、組換えポックスウイルス

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