JP2016536993A5 - - Google Patents

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Publication number
JP2016536993A5
JP2016536993A5 JP2016530177A JP2016530177A JP2016536993A5 JP 2016536993 A5 JP2016536993 A5 JP 2016536993A5 JP 2016530177 A JP2016530177 A JP 2016530177A JP 2016530177 A JP2016530177 A JP 2016530177A JP 2016536993 A5 JP2016536993 A5 JP 2016536993A5
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Japan
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coli
strain
modified
mutation
gene
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JP2016530177A
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English (en)
Japanese (ja)
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JP2016536993A (ja
JP6545676B2 (ja
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Priority claimed from PCT/US2014/065545 external-priority patent/WO2015073720A1/en
Publication of JP2016536993A publication Critical patent/JP2016536993A/ja
Publication of JP2016536993A5 publication Critical patent/JP2016536993A5/ja
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JP2016530177A 2013-11-14 2014-11-13 改善された代謝能力を有する細菌 Active JP6545676B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361904298P 2013-11-14 2013-11-14
US61/904,298 2013-11-14
PCT/US2014/065545 WO2015073720A1 (en) 2013-11-14 2014-11-13 Bacteria with improved metabolic capacity

Publications (3)

Publication Number Publication Date
JP2016536993A JP2016536993A (ja) 2016-12-01
JP2016536993A5 true JP2016536993A5 (https=) 2017-12-28
JP6545676B2 JP6545676B2 (ja) 2019-07-17

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ID=53058029

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JP2016530177A Active JP6545676B2 (ja) 2013-11-14 2014-11-13 改善された代謝能力を有する細菌

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US (2) US9902965B2 (https=)
EP (1) EP3068887B1 (https=)
JP (1) JP6545676B2 (https=)
WO (1) WO2015073720A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016161305A1 (en) 2015-04-02 2016-10-06 Scarab Genomics, Llc Materials and methods for extended continuous flow fermentation of reduced genome bacteria
CN115927299A (zh) 2016-03-15 2023-04-07 核糖核酸复兴股份有限责任公司 增加双链rna产生的方法和组合物
JP7296386B2 (ja) 2017-09-05 2023-06-22 スカラブ ゲノミクス, エルエルシー 組換えタンパク質の発現を改善するための方法および組成物
CN108587992B (zh) * 2018-04-10 2022-03-15 安徽大学 一种高效分泌表达抗VEGF-Fab抗体片段的高产菌株及其构建方法
US20220307038A1 (en) * 2019-05-30 2022-09-29 Rnaissance Ag Llc Improved methods and compositions for increased double stranded rna production
US20230167467A1 (en) * 2020-04-15 2023-06-01 University of Alaska Anchorage Methods and compositions for the production of isobutene
US12168679B2 (en) 2020-11-10 2024-12-17 Northwestern University Modified bacteria for enhanced bioproduction and methods of using the same
JP2026503706A (ja) 2023-01-25 2026-01-29 ノベル バイオテクノロジー ユーエスエー インコーポレイテッド 産物製造のための発現システム

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578464A (en) 1989-10-31 1996-11-26 Schering Corporation E. coli secretory strains
US5747662A (en) 1995-03-01 1998-05-05 Genentech, Inc. Methods and compositions for secretion of heterologous polypeptides
US6022952A (en) 1998-04-01 2000-02-08 University Of Alberta Compositions and methods for protein secretion
US8119365B2 (en) 2002-01-23 2012-02-21 Wisconsin Alumni Research Foundation Insertion sequence-free bacteria
US8039243B2 (en) 2002-01-23 2011-10-18 Wisconsin Alumni Research Foundation Insertion sequence-free bacteria
US6989265B2 (en) 2002-01-23 2006-01-24 Wisconsin Alumni Research Foundation Bacteria with reduced genome
US7303906B2 (en) 2002-09-06 2007-12-04 Wisconsin Alumni Research Foundation Competent bacteria
US7300776B2 (en) 2004-04-26 2007-11-27 Ajinomoto Co., Inc. L-amino acid-producing bacterium and a method for producing L-amino acid
US20080009041A1 (en) 2004-11-26 2008-01-10 Hiroshi Mizoguchi Industrially Useful Microorganism
EP2543726B1 (en) 2005-08-20 2018-10-03 Scarab Genomics, LLC Reduced genome E. coli
JP2009165355A (ja) * 2006-04-28 2009-07-30 Ajinomoto Co Inc L−アミノ酸を生産する微生物及びl−アミノ酸の製造法
WO2007140816A1 (en) * 2006-06-09 2007-12-13 Metabolic Explorer Glycolic acid production by fermentation from renewable resources
HUE025524T2 (en) 2008-02-22 2016-05-30 Scarab Genomics Llc Preparations and Methods for Biosynthesis of Amino Acid
US20110111458A1 (en) * 2008-03-18 2011-05-12 Kyowa Hakko Kirin Co., Ltd. Industrially useful microorganism
JP2013537429A (ja) * 2010-08-27 2013-10-03 メタボリック エクスプローラー 改変微生物による改良されたグリコール酸発酵生産
JP6151704B2 (ja) * 2011-10-20 2017-06-21 スカラブ ゲノミクス, エルエルシー 遺伝的安定性が向上したゲノム縮小化細菌
WO2015134402A1 (en) * 2014-03-03 2015-09-11 Scarab Genomics, Llc Enhanced production of recombinant crm197 in e. coli

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