JP2016530303A5 - - Google Patents

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Publication number
JP2016530303A5
JP2016530303A5 JP2016540943A JP2016540943A JP2016530303A5 JP 2016530303 A5 JP2016530303 A5 JP 2016530303A5 JP 2016540943 A JP2016540943 A JP 2016540943A JP 2016540943 A JP2016540943 A JP 2016540943A JP 2016530303 A5 JP2016530303 A5 JP 2016530303A5
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JP
Japan
Prior art keywords
compound
cells
combination
composition
cell
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JP2016540943A
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English (en)
Japanese (ja)
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JP2016530303A (ja
JP6659546B2 (ja
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Priority claimed from PCT/US2014/055021 external-priority patent/WO2015038662A1/en
Publication of JP2016530303A publication Critical patent/JP2016530303A/ja
Publication of JP2016530303A5 publication Critical patent/JP2016530303A5/ja
Application granted granted Critical
Publication of JP6659546B2 publication Critical patent/JP6659546B2/ja
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JP2016540943A 2013-09-10 2014-09-10 生細胞内への分子の送達のための組成物および方法 Active JP6659546B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361876006P 2013-09-10 2013-09-10
US61/876,006 2013-09-10
PCT/US2014/055021 WO2015038662A1 (en) 2013-09-10 2014-09-10 Compositions and methods for the delivery of molecules into live cells

Publications (3)

Publication Number Publication Date
JP2016530303A JP2016530303A (ja) 2016-09-29
JP2016530303A5 true JP2016530303A5 (https=) 2017-10-19
JP6659546B2 JP6659546B2 (ja) 2020-03-04

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ID=52666235

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016540943A Active JP6659546B2 (ja) 2013-09-10 2014-09-10 生細胞内への分子の送達のための組成物および方法

Country Status (7)

Country Link
US (2) US9662404B2 (https=)
EP (1) EP3043811B1 (https=)
JP (1) JP6659546B2 (https=)
AU (1) AU2014318839B2 (https=)
CA (1) CA2923664C (https=)
ES (1) ES2794599T3 (https=)
WO (1) WO2015038662A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2981716C (en) 2015-04-10 2022-04-12 Feldan Bio Inc. Polypeptide-based shuttle agents for improving the transduction efficiency of polypeptide cargos to the cytosol of target eukaryotic cells, uses thereof, methods and kits relating to same
FR3048698B1 (fr) 2016-03-11 2021-03-05 Univ Claude Bernard Lyon Inhibiteurs de l'interaction bcl2 l10 / recepteur ip3
CN110291100B (zh) * 2016-10-12 2024-06-11 费尔丹生物公司 用于将多肽负荷从细胞外空间递送至靶真核细胞的胞质溶胶和/或细胞核的合理设计的合成肽穿梭剂,其用途、与其相关的方法和试剂盒
US11629170B2 (en) 2016-10-12 2023-04-18 Feldan Bio Inc. Rationally-designed synthetic peptide shuttle agents for delivering polypeptide cargos from an extracellular space to the cytosol and/or nucleus of a target eukaryotic cell, uses thereof, methods and kits relating to same
EP3604520A4 (en) * 2017-03-22 2020-12-16 Kyoto University PEPTIDE FOR CYTOSOLIC ADMINISTRATION
US11821003B2 (en) 2017-08-14 2023-11-21 Sanford Burnham Prebys Medical Discovery Institute Cardiogenic mesoderm formation regulators
WO2020091535A1 (ko) * 2018-11-02 2020-05-07 순천향대학교 산학협력단 점막 투과 촉진용 펩타이드 및 이를 포함하는 조성물
JP2022512977A (ja) 2018-11-08 2022-02-07 サメイション バイオ, インコーポレイテッド ミニヌクレオソームコアタンパク質及び核酸送達における使用
KR102201154B1 (ko) * 2019-03-26 2021-01-12 가천대학교 산학협력단 폴리글루타메이트-TAT-Cre 융합 단백질의 제조방법
CA3040645A1 (en) 2019-04-18 2020-10-18 Feldan Bio Inc. Peptide-based non-proteinaceous cargo delivery
AU2021254697A1 (en) 2020-04-13 2022-11-10 Summation Bio Inc. Modified mini-nucleosome core proteins and use in nucleic acid delivery

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258774B1 (en) * 1998-03-19 2001-07-10 University Of Medicine And Dentistry Of New Jersey Carrier for in vivo delivery of a therapeutic agent
AU2006325030B2 (en) 2005-12-16 2012-07-26 Cellectis Cell penetrating peptide conjugates for delivering nucleic acids into cells
EP2224940A1 (en) * 2007-11-30 2010-09-08 Cytomatrix PTY LTD Methods of inducing pluripotency involving oct4 protein
WO2010059806A2 (en) * 2008-11-20 2010-05-27 Cedars-Sinai Medical Center Generation of induced pluripotent stem cells without the use of viral vectors
WO2010072228A1 (en) 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
US20120128655A1 (en) * 2009-04-03 2012-05-24 The Mclean Hospital Corporation Induced pluripotent stem cells
EP4321168A3 (en) * 2010-07-13 2024-04-24 Yale University, Inc. Environmentally sensitive compositions
WO2012090150A2 (en) 2010-12-27 2012-07-05 Compugen Ltd New cell-penetrating peptides and uses thereof

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