JP2016529309A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016529309A5 JP2016529309A5 JP2016539667A JP2016539667A JP2016529309A5 JP 2016529309 A5 JP2016529309 A5 JP 2016529309A5 JP 2016539667 A JP2016539667 A JP 2016539667A JP 2016539667 A JP2016539667 A JP 2016539667A JP 2016529309 A5 JP2016529309 A5 JP 2016529309A5
- Authority
- JP
- Japan
- Prior art keywords
- intestinal
- lactobacillus
- composition
- direct
- indirect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000968 intestinal Effects 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 13
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butanoic acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims 12
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 12
- 150000003839 salts Chemical class 0.000 claims 10
- 239000011780 sodium chloride Substances 0.000 claims 10
- 238000004519 manufacturing process Methods 0.000 claims 9
- 241000186660 Lactobacillus Species 0.000 claims 8
- 229940039696 Lactobacillus Drugs 0.000 claims 8
- 241000894006 Bacteria Species 0.000 claims 7
- 239000001384 succinic acid Substances 0.000 claims 6
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims 4
- 208000004300 Atrophic Gastritis Diseases 0.000 claims 2
- 206010009900 Colitis ulcerative Diseases 0.000 claims 2
- 208000001636 Diabetic Neuropathy Diseases 0.000 claims 2
- 206010012680 Diabetic neuropathy Diseases 0.000 claims 2
- 206010012735 Diarrhoea Diseases 0.000 claims 2
- 206010013554 Diverticulum Diseases 0.000 claims 2
- 208000004232 Enteritis Diseases 0.000 claims 2
- 229960000304 Folic Acid Drugs 0.000 claims 2
- 229940053207 Niacin Drugs 0.000 claims 2
- 206010061876 Obstruction Diseases 0.000 claims 2
- 230000001419 dependent Effects 0.000 claims 2
- 201000008286 diarrhea Diseases 0.000 claims 2
- 235000019152 folic acid Nutrition 0.000 claims 2
- 239000011724 folic acid Substances 0.000 claims 2
- DFPAKSUCGFBDDF-UHFFFAOYSA-N nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims 2
- 229960003512 nicotinic acid Drugs 0.000 claims 2
- 235000001968 nicotinic acid Nutrition 0.000 claims 2
- 239000011664 nicotinic acid Substances 0.000 claims 2
- 230000000414 obstructive Effects 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000001737 promoting Effects 0.000 claims 2
- 230000036262 stenosis Effects 0.000 claims 2
- 200000000009 stenosis Diseases 0.000 claims 2
- 201000006704 ulcerative colitis Diseases 0.000 claims 2
- 241001202853 Blautia Species 0.000 claims 1
- 241001464948 Coprococcus Species 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 210000000936 Intestines Anatomy 0.000 claims 1
- 241000186610 Lactobacillus sp. Species 0.000 claims 1
- 229940029983 VITAMINS Drugs 0.000 claims 1
- 229940021016 Vitamin IV solution additives Drugs 0.000 claims 1
- 230000001580 bacterial Effects 0.000 claims 1
- 235000013325 dietary fiber Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000000284 extract Substances 0.000 claims 1
- 244000005709 gut microbiome Species 0.000 claims 1
- 230000003903 intestinal lesions Effects 0.000 claims 1
- 230000004674 intestinal mucosal integrity Effects 0.000 claims 1
- 239000006166 lysate Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 235000013406 prebiotics Nutrition 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 235000013619 trace mineral Nutrition 0.000 claims 1
- 239000011573 trace mineral Substances 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 229930003231 vitamins Natural products 0.000 claims 1
Claims (12)
- 酪酸及び／若しくはその塩、及び／又は葉酸及び／若しくはその塩、及び／又はナイアシン及び／若しくはその塩の、直接的及び／又は間接的腸内産生を増加させるための、及び／又はコハク酸及び／若しくはその塩の、直接的及び／又は間接的腸内産生を低下させるための、ラクトバシルス（Lactobacillus）属パラカゼイ（paracasei）種の少なくとも１種の細菌を含む組成物。
- 酪酸及び／若しくはその塩の腸内産生の直接的及び／若しくは間接的増加により、及び／又はコハク酸及び／若しくはその塩の腸内産生の直接的及び／若しくは間接的低下により、病原性微生物の腸内増殖を低下させるための、及び／又は腸粘膜の完全性を促進するための、及び／又は腸病変の修復プロセスを促進するための、請求項１に記載の組成物。
- 腸の酪酸及び／又はコハク酸依存性の病状の治療及び/又は予防に使用するための、ラクトバシルス（Lactobacillus）属パラカゼイ（paracasei）種の少なくとも１種の細菌を含む組成物。
- 前記腸の病状が、下痢、腸炎、潰瘍性大腸炎、胃の萎縮、腸憩室、狭窄症、閉塞、及び糖尿病性神経障害から選択される、請求項３に記載の組成物。
- 前記ラクトバシルス（Lactobacillus）がラクトバシルス・パラカセイ（Lactobacillus
paracasei）ＤＧ株である、請求項１〜４のいずれか１項に記載の組成物。 - 酪酸及び／若しくはその塩、及び／又は葉酸及び／若しくはその塩、及び／又はナイアシン及び／若しくはその塩の、腸内産生の前記直接的及び／若しくは間接的増加が、及び／又はコハク酸の腸内産生の前記直接的及び／若しくは間接的低下が、腸内微生物叢に起因する、請求項１、２、及び５のいずれか１項に記載の組成物。
- 酪酸及び／若しくはその塩の腸内産生の前記直接的及び／若しくは間接的増加は、コプロコッカス（Coprococcus）属の細菌に起因し、及び／又は、コハク酸の腸内産生の前記直接的及び／若しくは間接的低下は、ブラウチア（Blautia）属の細菌に起因する、請求項１、２、５、及び６のいずれか１項に記載の組成物。
- ラクトバシルス（Lactobacillus）属パラカゼイ（paracasei）種の前記少なくとも１種の細菌が、生きているか若しくは死んだ細菌であるか、又は細菌溶解物若しくは抽出物である、請求項１〜７のいずれか１項に記載の組成物。
- 前記組成物が、経口投与用である、請求項１〜８のいずれか１項に記載の組成物。
- 前記組成物が、プレバイオティクス活性を有する食物繊維をさらに含むか、又はビタミン、微量元素、及び酵素から選ばれる物質を含む、請求項１〜９のいずれか１項に記載の組成物。
- 腸の酪酸及び／又はコハク酸依存性の病状の治療及び/又は予防に使用するための医薬を製造するための、ラクトバシルス（Lactobacillus）属パラカゼイ（paracasei）種の少なくとも１種の細菌を含む組成物の使用。
- 前記腸の病状が、下痢、腸炎、潰瘍性大腸炎、胃の萎縮、腸憩室、狭窄症、閉塞、及び糖尿病性神経障害から選択される、請求項１１に記載の使用。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001467A ITMI20131467A1 (it) | 2013-09-06 | 2013-09-06 | Uso di una composizione comprendente microrganismi per aumentare la produzione intestinale di acido butirrico, di acido folico o di niacina e/o per diminuire la produzione intestinale di acido succinico |
| ITMI2013A001467 | 2013-09-06 | ||
| PCT/IB2014/064285 WO2015033305A1 (en) | 2013-09-06 | 2014-09-05 | Use of a composition comprising microorganisms to increase the intestinal production of butyric acid, folic acid or niacin and/or decrease the intestinal production of succinic acid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016529309A JP2016529309A (ja) | 2016-09-23 |
| JP2016529309A5 true JP2016529309A5 (ja) | 2017-10-19 |
| JP6651450B2 JP6651450B2 (ja) | 2020-02-19 |
Family
ID=49354800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016539667A Active JP6651450B2 (ja) | 2013-09-06 | 2014-09-05 | 酪酸、葉酸、又はナイアシンの腸内産生を増加させるための、及び／又はコハク酸の腸内産生を低下させるための、微生物を含む組成物の使用 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US11839634B2 (ja) |
| EP (1) | EP3041489B1 (ja) |
| JP (1) | JP6651450B2 (ja) |
| CN (2) | CN115804798A (ja) |
| AU (1) | AU2014316688B2 (ja) |
| BR (1) | BR112016005059B1 (ja) |
| CA (1) | CA2923392C (ja) |
| CY (1) | CY1123127T1 (ja) |
| DK (1) | DK3041489T3 (ja) |
| EA (1) | EA036534B1 (ja) |
| ES (1) | ES2805471T3 (ja) |
| HK (1) | HK1224192A1 (ja) |
| HR (1) | HRP20201065T1 (ja) |
| HU (1) | HUE050146T2 (ja) |
| IL (2) | IL244392B (ja) |
| IT (1) | ITMI20131467A1 (ja) |
| LT (1) | LT3041489T (ja) |
| ME (1) | ME03805B (ja) |
| MX (1) | MX2016002765A (ja) |
| PL (1) | PL3041489T3 (ja) |
| PT (1) | PT3041489T (ja) |
| RS (1) | RS60518B1 (ja) |
| SG (2) | SG11201601662SA (ja) |
| SI (1) | SI3041489T1 (ja) |
| WO (1) | WO2015033305A1 (ja) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7387587B2 (ja) | 2017-09-12 | 2023-11-28 | ラチドゥーエビオメ・エッセ・エッレ・エッレ | クロストリジウム・ディフィシル感染症の治療における新たな使用 |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| ITMI20131467A1 (it) | 2013-09-06 | 2015-03-07 | Sofar Spa | Uso di una composizione comprendente microrganismi per aumentare la produzione intestinale di acido butirrico, di acido folico o di niacina e/o per diminuire la produzione intestinale di acido succinico |
| MA39710A (fr) | 2014-04-23 | 2015-10-29 | Sofar Spa | Composition topique destinée à être utilisée dans le traitement d'une maladie inflammatoire de l'intestin |
| MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| HUE044617T2 (hu) | 2015-06-15 | 2019-11-28 | 4D Pharma Res Ltd | Baktériumtörzseket tartalmazó készítmények |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| MA45327A (fr) | 2016-05-13 | 2019-03-20 | Sofar Spa | Utilisation de probiotiques pour améliorer l'absorption des protéines |
| MA45288A (fr) | 2016-06-08 | 2019-04-17 | Sofar Spa | Nouvelle utilisation médicale de probiotiques |
| TWI802545B (zh) | 2016-07-13 | 2023-05-21 | 英商４Ｄ製藥有限公司 | 包含細菌菌株之組合物 |
| IT201600122724A1 (it) | 2016-12-02 | 2018-06-02 | Sofar Spa | Exopolysaccharides and uses thereof |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| IT201600127498A1 (it) | 2016-12-16 | 2018-06-16 | Sofar Spa | Probiotici per uso nella diverticolosi e malattia diverticolare |
| GB201704525D0 (en) | 2017-03-22 | 2017-05-03 | Central Glass Co Ltd | Vehicle glass window with electrical connector soldered by lead-free solder |
| EP3630137B1 (en) * | 2017-05-22 | 2023-05-17 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| MA41708A (fr) | 2017-05-24 | 2020-04-08 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| SI3638271T1 (sl) | 2017-06-14 | 2021-01-29 | 4D Pharma Research Limited | Sestavki, ki vsebujejo bakterijske seve |
| PL3600364T3 (pl) | 2017-06-14 | 2021-01-11 | 4D Pharma Research Limited | Kompozycje zawierające szczep bakteryjny z rodzaju megasphaera i ich zastosowania |
| AU2018378419A1 (en) * | 2017-12-06 | 2020-07-09 | Lac2biome S.r.l. | Composition based on probiotics and uses thereof |
| MX2020007619A (es) * | 2018-01-17 | 2020-09-28 | Consorcio Centro De Investig Biomedica En Red M P | Intervenciones dirigidas, encaminadas a reducir los niveles de succinato circulante en un sujeto, y kits y metodo para determinar la eficacia de dichas intervenciones. |
| CN110358712B (zh) * | 2019-07-26 | 2021-11-09 | 浙江一鸣食品股份有限公司 | 一种乳酸菌组合物及其应用 |
| CN110358714A (zh) * | 2019-08-01 | 2019-10-22 | 浙江一鸣食品股份有限公司 | 一种高产叶酸的乳酸菌组合物 |
| CN110669697B (zh) * | 2019-10-31 | 2022-07-15 | 微康益生菌(苏州)股份有限公司 | 一种高产短链脂肪酸的干酪乳杆菌、培养方法及其应用 |
| US11751597B2 (en) | 2019-11-05 | 2023-09-12 | Alfasigma S.P.A. | Compositions comprising bacterial strains for use in increasing the bioavailability of amino acids derived from proteins, and related food product methods and systems |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0517363A (ja) | 1991-07-11 | 1993-01-26 | Yakult Honsha Co Ltd | 抗炎症剤及びそれを含有する化粧料 |
| US5716615A (en) | 1992-02-10 | 1998-02-10 | Renata Maria Anna Cavaliere Vesely | Dietary and pharmaceutical compositions containing lyophilized lactic bacteria, their preparation and use |
| US5531989A (en) | 1994-10-28 | 1996-07-02 | Metagenics, Inc. | Immunoglobulin and fiber-containing composition for human gastrointestinal health |
| CN1066926C (zh) | 1996-04-08 | 2001-06-13 | 钟春燕 | 将椰子水发酵制作的食用纤维及其生产方法 |
| US6461607B1 (en) | 1998-08-24 | 2002-10-08 | Ganeden Biotech, Inc. | Probiotic, lactic acid-producing bacteria and uses thereof |
| CZ9900769A3 (cs) | 1999-03-04 | 2000-10-11 | Petr Ing. Drsc. Hušek | Použití špičky s filtrem k vytvoření sloupce sorbentu s definovaným objemem v prostoru pod filtrem |
| US20020090416A1 (en) | 1999-03-09 | 2002-07-11 | Philip Connolly | Method of enhancing absorption and utilization of protein |
| IT1307850B1 (it) * | 1999-03-15 | 2001-11-19 | Italmed Di Galli Giovanna E Pa | Composizione farmaceutica a base di fermenti lattici e carboidratinon assorbibili contenente un sale di calcio ed un sale di alluminio |
| EP1145643A1 (en) | 2000-04-10 | 2001-10-17 | Phillip Connolly | Improved milk protein concentrate |
| US20040170617A1 (en) | 2000-06-05 | 2004-09-02 | Finegold Sydney M. | Method of treating diseases associated with abnormal gastrointestinal flora |
| RU2182008C1 (ru) | 2000-10-20 | 2002-05-10 | Самойленко Игорь Иннокентьевич | Вводимая перорально, ректально или интравагинально композиция, содержащая живые бактерии |
| PE20030284A1 (es) * | 2001-07-26 | 2003-05-01 | Alimentary Health Ltd | Cepas de bifidobacterium |
| FI20020078A (fi) * | 2002-01-15 | 2003-07-16 | Danisco | Immuunijärjestelmän stimulointi polydextroosilla |
| US6881419B2 (en) * | 2002-04-09 | 2005-04-19 | William E. Lovett | Vitamin formulation for enhancing bone strength |
| AU2002309180A1 (en) | 2002-04-24 | 2003-11-10 | Medicarb Ab | Composition and kit for the treatment of inflammatory bowel diseases |
| DE60330781D1 (de) * | 2002-08-06 | 2010-02-11 | Danisco | Anwendung von lactobacillus zur herstellung von exopolysacchariden in nahrungsmittel und pharmazeutische zusammensetzungen |
| AU2002951270A0 (en) | 2002-09-06 | 2002-09-19 | Vri Biomedical Ltd | Probiotic Bacterium and Methods of Use |
| WO2005001109A2 (en) | 2003-05-06 | 2005-01-06 | Government Of The United States Of America As Represented By The Sercretary Of The Department Of Health And Human Services National Institutes Of Health | Methods and compositions to detect microbes in fecal samples |
| US20100112088A1 (en) * | 2003-08-29 | 2010-05-06 | Jay Pravda | Materials and methods for treatment of disorders associated with oxidative stress |
| CA2557543A1 (en) | 2004-02-27 | 2005-09-09 | Stichting Laboratorium Voor Infectieziekten | Method for detecting a microorganism in a fecal specimen |
| EP1722804B1 (en) | 2004-03-04 | 2015-01-21 | E-L Management Corp. | Skin treatment method with lactobacillus extract |
| CA2587670A1 (en) | 2004-11-01 | 2006-05-11 | George Mason University | Compositions and methods for diagnosing colon disorders |
| WO2006108008A2 (en) * | 2005-04-06 | 2006-10-12 | Novartis Ag | A method and composition for nutritionally improving glucose control and insulin action |
| FI20051319L (fi) | 2005-12-22 | 2007-06-23 | Cyflo Oy | Menetelmä eläimen ja/tai ihmisen ravitsemuksen ja hyvinvoinnin ja eläinten tuottavuuden seuraamiseksi ja kehittämiseksi |
| CN1840206A (zh) | 2006-01-19 | 2006-10-04 | 上海交通大学 | 人源菌群仔猪模型的构建及仔猪肠道中菌群分子检测方法 |
| JP4590573B2 (ja) | 2006-02-21 | 2010-12-01 | 国立大学法人富山大学 | 感染症起因菌の迅速同定方法 |
| CN101415731B (zh) | 2006-02-24 | 2011-11-02 | 丘比株式会社 | 新型低分子透明质酸和/或其盐以及使用其的化妆品、医药组合物和食品组合物 |
| US20100166721A1 (en) | 2006-06-09 | 2010-07-01 | Fabiola Masri | Probotic compositions and uses thereof |
| US20080069861A1 (en) | 2006-09-19 | 2008-03-20 | National Starch And Chemical Investment Holding Corporation | Probiotic/Non-Probiotic Combinations |
| US20080081035A1 (en) * | 2006-10-03 | 2008-04-03 | National Enzyme Company | Therapeutic protease compositions |
| CA2673120C (en) | 2006-12-18 | 2012-08-07 | Advanced Bionutrition Corporation | A dry food product containing live probiotic |
| EP1972208A1 (en) * | 2007-03-16 | 2008-09-24 | Kirin Holdings Kabushiki Kaisha | Composition for improving intestinal microflora |
| BRPI0809454A2 (pt) | 2007-03-27 | 2014-09-09 | Procter & Gamble | Métodos e kits para a administração de probióticos |
| CA2687192C (en) | 2007-06-04 | 2015-11-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
| PT2173196E (pt) * | 2007-07-06 | 2011-05-23 | Nutricia Nv | Uso de probi?ticos e fibras para a diarreia |
| US8193155B2 (en) | 2009-02-09 | 2012-06-05 | Elc Management, Llc | Method and compositions for treating skin |
| US20090098088A1 (en) | 2007-10-10 | 2009-04-16 | The Procter & Gamble Company | Methods And Kits For The Treatment Of Diverticular Conditions |
| CN101240315A (zh) | 2008-02-21 | 2008-08-13 | 上海交通大学 | 检测药物防癌效果的非损伤性分子方法 |
| CA2721981A1 (en) | 2008-05-01 | 2009-11-05 | The Procter & Gamble Company | Methods and kits for the treatment of inflammatory bowel disorder conditions |
| WO2010008272A1 (en) | 2008-07-15 | 2010-01-21 | N.V. Nutricia | Treatment of gut motility disorders |
| JP2010161944A (ja) | 2009-01-13 | 2010-07-29 | Syngen Biotech Co Ltd | 新型カゼイ菌の亜種（ｓｇ９６）及びこれを含有する菌抑制組成物及びその用途 |
| RU2011139211A (ru) | 2009-03-05 | 2013-04-10 | Пробиотикал С.п.А. | Бактериальные штаммы, обладающие высокой противовоспалительной активностью |
| WO2010103132A1 (es) | 2009-03-10 | 2010-09-16 | Hero España, S.A. | Aislamiento, identificación y caracterización de cepas con actividad probiótica a partir de heces de lactantes alimentados exclusivamente con leche materna |
| US20120177650A1 (en) | 2009-09-23 | 2012-07-12 | Borody Thomas J | Therapy for enteric infections |
| JP6006117B2 (ja) * | 2009-11-12 | 2016-10-12 | ネステク ソシエテ アノニム | 腸内微生物叢バランス及び健康を促進するための栄養組成物 |
| BR112012015033B1 (pt) | 2009-12-22 | 2020-11-03 | Probi Ab | uso de uma composição não fermentada |
| US8575130B2 (en) | 2010-01-04 | 2013-11-05 | Holy Stone Healthcare Co., Ltd. | Mixture of hyaluronic acid for treating and preventing inflammatory bowel disease |
| ITUD20100112A1 (it) | 2010-06-09 | 2011-12-10 | Farma Derma S R L | Preparazione per uso vaginale e rettale e relativo procedimento di produzione |
| WO2012135499A1 (en) | 2011-03-31 | 2012-10-04 | Ganeden Biotech, Inc. | Probiotic sports nutrition compositions |
| WO2012154738A1 (en) | 2011-05-09 | 2012-11-15 | The Cleveland Clinic Foundation | Composition and method to improve intestinal health |
| EP3366143A1 (en) | 2011-06-20 | 2018-08-29 | H.J. Heinz Company Brands LLC | Probiotic compositions and methods |
| GB201219873D0 (en) | 2012-11-05 | 2012-12-19 | Multigerm Uk Entpr Ltd | Diverticulitis treatment |
| CN102919922A (zh) | 2012-11-08 | 2013-02-13 | 黑龙江省轻工科学研究院 | 一种复合益生菌发酵蓝莓果汁粉的制备方法 |
| JP2016511272A (ja) * | 2013-03-05 | 2016-04-14 | レイクスユニフェルシテイト フローニンゲン | 炎症を抑制するためのフィーカリバクテリウム・パラウスニッチィーｈｔｆ−ｆ（ｄｓｍ２６９４３）の使用 |
| JP6643984B2 (ja) | 2013-07-02 | 2020-02-12 | オーストリアノヴァ シンガポール プライベート リミテッド | カプセル化細胞を凍結乾燥する方法、凍結乾燥されたカプセル化細胞、凍結乾燥されたカプセル化細胞を含む組成物、ならびに、そのような細胞および組成物の使用 |
| ITMI20131467A1 (it) | 2013-09-06 | 2015-03-07 | Sofar Spa | Uso di una composizione comprendente microrganismi per aumentare la produzione intestinale di acido butirrico, di acido folico o di niacina e/o per diminuire la produzione intestinale di acido succinico |
| ITMI20131473A1 (it) | 2013-09-06 | 2015-03-07 | Sofar Spa | Metodo per valutare gli effetti di una composizione comprendente microrganismi sul microbiota intestinale |
| MA39710A (fr) | 2014-04-23 | 2015-10-29 | Sofar Spa | Composition topique destinée à être utilisée dans le traitement d'une maladie inflammatoire de l'intestin |
| WO2015172191A1 (en) | 2014-05-12 | 2015-11-19 | Medlab Ip Pty Ltd | Probiotic compositions and uses thereof for treatment of obesity-related disorders |
| DK2990045T3 (en) | 2014-08-26 | 2017-02-13 | Chr Hansen As | Bifidobacterium animalis subsp. lactis for use in reducing abdominal pain in a postmenopausal woman |
| WO2017195182A1 (en) | 2016-05-13 | 2017-11-16 | Sofar S.P.A. | Use of probiotics for improving protein absorption |
| MA45327A (fr) | 2016-05-13 | 2019-03-20 | Sofar Spa | Utilisation de probiotiques pour améliorer l'absorption des protéines |
| MA45288A (fr) | 2016-06-08 | 2019-04-17 | Sofar Spa | Nouvelle utilisation médicale de probiotiques |
| IT201600122724A1 (it) | 2016-12-02 | 2018-06-02 | Sofar Spa | Exopolysaccharides and uses thereof |
| IT201600127498A1 (it) | 2016-12-16 | 2018-06-16 | Sofar Spa | Probiotici per uso nella diverticolosi e malattia diverticolare |
| RU2744271C2 (ru) | 2016-12-16 | 2021-03-04 | Компани Жервэ Данон | Пробиотическая композиция, содержащая штаммы Lactobacillus rhamnosus и Lactobacillus paracasei |
| WO2019019961A1 (zh) | 2017-07-26 | 2019-01-31 | 海思科医药集团股份有限公司 | 防治消化道和/或皮肤反应的菌群及其应用 |
| IT201700101704A1 (it) | 2017-09-12 | 2019-03-12 | Sofar Spa | Nuovo uso per trattamento delle infezioni da clostridium difficile |
| AU2018378419A1 (en) | 2017-12-06 | 2020-07-09 | Lac2biome S.r.l. | Composition based on probiotics and uses thereof |
| CN108743851A (zh) | 2018-08-09 | 2018-11-06 | 深圳市博奥生物科技有限公司 | 一种复合益生菌粉的制备方法及复合益生菌粉 |
| IT201900016811A1 (it) | 2019-09-20 | 2021-03-20 | Sofar Spa | Ceppi batterici, loro composizioni e loro uso per il trattamento di disturbi gastrointestinali |
| IT201900016850A1 (it) | 2019-09-20 | 2021-03-20 | Sofar Spa | Composizioni a base di ceppi batterici e estratti di bacche e loro uso come antinfiammatori |
| IT201900016805A1 (it) | 2019-09-20 | 2021-03-20 | Sofar Spa | Ceppi batterici, loro composizioni e loro uso per il trattamento di disturbi gastrointestinali |
| IT201900016865A1 (it) | 2019-09-20 | 2021-03-20 | Sofar Spa | Composizioni a base di ceppi batterici e loro uso come antinfiammatori |
| IT201900020422A1 (it) | 2019-11-05 | 2021-05-05 | Sofar Spa | Composizioni comprendenti ceppi di batteri per uso per aumentare la biodisponibilità degli amminoacidi derivanti da proteine |
| US11751597B2 (en) | 2019-11-05 | 2023-09-12 | Alfasigma S.P.A. | Compositions comprising bacterial strains for use in increasing the bioavailability of amino acids derived from proteins, and related food product methods and systems |
-
2013
- 2013-09-06 IT IT001467A patent/ITMI20131467A1/it unknown
-
2014
- 2014-09-05 WO PCT/IB2014/064285 patent/WO2015033305A1/en active Application Filing
- 2014-09-05 BR BR112016005059-2A patent/BR112016005059B1/pt active IP Right Grant
- 2014-09-05 CN CN202211362855.XA patent/CN115804798A/zh not_active Withdrawn
- 2014-09-05 CA CA2923392A patent/CA2923392C/en active Active
- 2014-09-05 ES ES14790323T patent/ES2805471T3/es active Active
- 2014-09-05 PT PT147903231T patent/PT3041489T/pt unknown
- 2014-09-05 SG SG11201601662SA patent/SG11201601662SA/en unknown
- 2014-09-05 PL PL14790323T patent/PL3041489T3/pl unknown
- 2014-09-05 RS RS20200806A patent/RS60518B1/sr unknown
- 2014-09-05 ME MEP-2020-143A patent/ME03805B/me unknown
- 2014-09-05 HU HUE14790323A patent/HUE050146T2/hu unknown
- 2014-09-05 CN CN201480049296.4A patent/CN105916513A/zh active Pending
- 2014-09-05 AU AU2014316688A patent/AU2014316688B2/en active Active
- 2014-09-05 US US14/916,961 patent/US11839634B2/en active Active
- 2014-09-05 LT LTEP14790323.1T patent/LT3041489T/lt unknown
- 2014-09-05 EP EP14790323.1A patent/EP3041489B1/en active Active
- 2014-09-05 JP JP2016539667A patent/JP6651450B2/ja active Active
- 2014-09-05 EA EA201690464A patent/EA036534B1/ru unknown
- 2014-09-05 SI SI201431610T patent/SI3041489T1/sl unknown
- 2014-09-05 MX MX2016002765A patent/MX2016002765A/es active IP Right Grant
- 2014-09-05 DK DK14790323.1T patent/DK3041489T3/da active
- 2014-09-05 SG SG10202001331PA patent/SG10202001331PA/en unknown
-
2016
- 2016-03-02 IL IL244392A patent/IL244392B/en active IP Right Grant
- 2016-10-28 HK HK16112483.1A patent/HK1224192A1/zh unknown
-
2019
- 2019-09-03 IL IL269107A patent/IL269107B/en active IP Right Grant
-
2020
- 2020-07-07 HR HRP20201065TT patent/HRP20201065T1/hr unknown
- 2020-07-13 CY CY20201100642T patent/CY1123127T1/el unknown
-
2023
- 2023-10-24 US US18/493,221 patent/US20240050497A1/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7387587B2 (ja) | 2017-09-12 | 2023-11-28 | ラチドゥーエビオメ・エッセ・エッレ・エッレ | クロストリジウム・ディフィシル感染症の治療における新たな使用 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016529309A5 (ja) | ||
| JP2019520340A5 (ja) | ||
| HRP20180152T1 (hr) | Sojevi bakterija koji su izolirani iz svinja | |
| MY187630A (en) | Pediatric nutritional composition with human milk oligosaccharides, prebiotics and probiotics | |
| EA201390305A1 (ru) | Композиции для влагалищного и перорального введения lactobacillus и их применение | |
| EP3904502A3 (en) | Compositions and methods | |
| EA201391823A1 (ru) | Высушенные распылением штаммы/клетки лактобактерий и их применение против helicobacter pylori | |
| ITMI20131467A1 (it) | Uso di una composizione comprendente microrganismi per aumentare la produzione intestinale di acido butirrico, di acido folico o di niacina e/o per diminuire la produzione intestinale di acido succinico | |
| MX2009009442A (es) | Probioticos para mejorar la microbiota intestinal. | |
| BR112012010398A2 (pt) | metodo para reduzir a inflamação gastrointestinal usando a bactéria bifidobacterium animalis ou um produto laticínio fermentado compreendendo tal bactéria | |
| RU2016143195A (ru) | Применение lactobacilius rhamnosus для стимулирования восстановления разнообразия кишечной микробиоты после дисбактериоза | |
| JP2008538288A5 (ja) | ||
| JP2019508486A5 (ja) | ||
| JP2013147469A5 (ja) | ||
| BR112013028709A2 (pt) | cepas bacterianas capazes de metabolizar oxalatos | |
| CN107405369A8 (zh) | 包含细菌的组合物及将其用于治疗和/或预防胃肠道疾病、代谢疾病和/或其它疾病的方法 | |
| JP2016537410A5 (ja) | ||
| RU2018129984A (ru) | Пробиотики и способы их применения | |
| WO2015177246A8 (en) | Neonatal microbiome supplementation | |
| RU2018139655A (ru) | Бифидобактерии для увеличения безжировой массы тела | |
| RU2014106509A (ru) | Получение и применение бактериального гистамина | |
| Al-Ghazzewi et al. | Inhibition of the adhesion of Escherichia coli to human epithelial cells by carbohydrates | |
| RU2018139656A (ru) | Бифидобактерии для снижения потребления пищи, энергии и/или жиров | |
| Yang et al. | Effects of Lacidophilin Tablets, Yogurt, and Bifid Triple Viable Capsules on the Gut Microbiota of Mice with Antibiotic‐Associated Diarrhea | |
| JP2016508368A5 (ja) |