JP2016525890A - 遺伝的不妊性動物 - Google Patents

遺伝的不妊性動物 Download PDF

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Publication number
JP2016525890A
JP2016525890A JP2016516661A JP2016516661A JP2016525890A JP 2016525890 A JP2016525890 A JP 2016525890A JP 2016516661 A JP2016516661 A JP 2016516661A JP 2016516661 A JP2016516661 A JP 2016516661A JP 2016525890 A JP2016525890 A JP 2016525890A
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gene
animal
cell
animals
sperm
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Japanese (ja)
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JP2016525890A5 (enExample
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ダニエル・エフ・カールソン
スコット・シー・ファーレンクラッグ
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Recombinetics Inc
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Recombinetics Inc
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276—Knock-out vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0273—Cloned vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A01K2217/077—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out heterozygous knock out animals displaying phenotype
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/101—Bovine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/103—Ovine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/108—Swine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
JP2016516661A 2013-05-31 2014-04-29 遺伝的不妊性動物 Pending JP2016525890A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361829656P 2013-05-31 2013-05-31
US61/829,656 2013-05-31
US201361870558P 2013-08-27 2013-08-27
US61/870,558 2013-08-27
PCT/US2014/035847 WO2014193583A2 (en) 2013-05-31 2014-04-29 Genetically sterile animals

Publications (2)

Publication Number Publication Date
JP2016525890A true JP2016525890A (ja) 2016-09-01
JP2016525890A5 JP2016525890A5 (enExample) 2017-06-15

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JP2016516661A Pending JP2016525890A (ja) 2013-05-31 2014-04-29 遺伝的不妊性動物

Country Status (13)

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US (2) US20140359796A1 (enExample)
EP (1) EP3004345A4 (enExample)
JP (1) JP2016525890A (enExample)
KR (1) KR20160013219A (enExample)
CN (1) CN105473714A (enExample)
AP (1) AP2015008963A0 (enExample)
AU (1) AU2014272106A1 (enExample)
BR (1) BR112015029904A2 (enExample)
CA (1) CA2913411A1 (enExample)
MX (1) MX2015016385A (enExample)
PH (1) PH12015502640A1 (enExample)
RU (1) RU2015156801A (enExample)
WO (1) WO2014193583A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2022502064A (ja) * 2018-10-12 2022-01-11 ザ ユニバーシティー コート オブ ザ ユニバーシティー オブ エジンバラThe University Court Of The University Of Edinburgh 遺伝子改変不妊鳥類およびその再構成方法

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US9322037B2 (en) 2013-09-06 2016-04-26 President And Fellows Of Harvard College Cas9-FokI fusion proteins and uses thereof
US9526784B2 (en) 2013-09-06 2016-12-27 President And Fellows Of Harvard College Delivery system for functional nucleases
US9340800B2 (en) 2013-09-06 2016-05-17 President And Fellows Of Harvard College Extended DNA-sensing GRNAS
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US9745561B2 (en) * 2014-01-08 2017-08-29 Iowa State University Research Foundation, Inc. Genetic test and genetic basis for SCID in pigs
AP2016009588A0 (en) 2014-04-28 2016-11-30 Recombinetics Inc Multiplex gene editing in swine
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WO2016022363A2 (en) 2014-07-30 2016-02-11 President And Fellows Of Harvard College Cas9 proteins including ligand-dependent inteins
WO2016163386A1 (ja) 2015-04-08 2016-10-13 全国農業協同組合連合会 異個体由来の配偶子を生産する非ヒト大型哺乳動物又は魚類の作出方法
WO2016196887A1 (en) 2015-06-03 2016-12-08 Board Of Regents Of The University Of Nebraska Dna editing using single-stranded dna
US20170099813A1 (en) * 2015-10-07 2017-04-13 Recombinetics, Inc. Method of generating sterile terminal sires in livestock and animals produced thereby
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Publication number Priority date Publication date Assignee Title
JP2022502064A (ja) * 2018-10-12 2022-01-11 ザ ユニバーシティー コート オブ ザ ユニバーシティー オブ エジンバラThe University Court Of The University Of Edinburgh 遺伝子改変不妊鳥類およびその再構成方法
JP7535792B2 (ja) 2018-10-12 2024-08-19 ザ ユニバーシティー コート オブ ザ ユニバーシティー オブ エジンバラ 遺伝子改変不妊鳥類およびその再構成方法

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WO2014193583A2 (en) 2014-12-04
CA2913411A1 (en) 2014-12-04
AP2015008963A0 (en) 2016-01-31
US20140359796A1 (en) 2014-12-04
MX2015016385A (es) 2016-04-11
AU2014272106A1 (en) 2016-01-21
WO2014193583A3 (en) 2015-01-22
CN105473714A (zh) 2016-04-06
EP3004345A4 (en) 2017-02-15
PH12015502640A1 (en) 2016-03-07
BR112015029904A2 (pt) 2017-09-26
KR20160013219A (ko) 2016-02-03
NZ715540A (en) 2021-04-30
RU2015156801A (ru) 2017-07-06
EP3004345A2 (en) 2016-04-13
US20190335725A1 (en) 2019-11-07

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