JP2016525548A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016525548A5 JP2016525548A5 JP2016529872A JP2016529872A JP2016525548A5 JP 2016525548 A5 JP2016525548 A5 JP 2016525548A5 JP 2016529872 A JP2016529872 A JP 2016529872A JP 2016529872 A JP2016529872 A JP 2016529872A JP 2016525548 A5 JP2016525548 A5 JP 2016525548A5
- Authority
- JP
- Japan
- Prior art keywords
- combination
- desmopressin
- combination medicament
- hours
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 20
- 108010000437 Deamino Arginine Vasopressin Proteins 0.000 claims 11
- NFLWUMRGJYTJIN-NXBWRCJVSA-N desmopressin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 NFLWUMRGJYTJIN-NXBWRCJVSA-N 0.000 claims 11
- 229960004281 desmopressin Drugs 0.000 claims 11
- 102000016959 beta-3 Adrenergic Receptors Human genes 0.000 claims 3
- 108010014502 beta-3 Adrenergic Receptors Proteins 0.000 claims 3
- 230000036470 plasma concentration Effects 0.000 claims 3
- 230000002686 anti-diuretic effect Effects 0.000 claims 2
- PBAPPPCECJKMCM-IBGZPJMESA-N mirabegron Chemical compound S1C(N)=NC(CC(=O)NC=2C=CC(CCNC[C@H](O)C=3C=CC=CC=3)=CC=2)=C1 PBAPPPCECJKMCM-IBGZPJMESA-N 0.000 claims 2
- 229960001551 mirabegron Drugs 0.000 claims 2
- 210000002200 mouth mucosa Anatomy 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- XSOXUIXLUNBLJA-RNRVQEDPSA-N (2r)-6-[(2r)-2-[[(2r)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid Chemical compound C1([C@@H](O)CN[C@@H](CC=2C=C3OC[C@@H](OC3=CC=2)C(O)=O)C)=CC=CC(Cl)=C1 XSOXUIXLUNBLJA-RNRVQEDPSA-N 0.000 claims 1
- ZGGNJJJYUVRADP-ACJLOTCBSA-N 2-[4-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetic acid Chemical compound C([C@@H](C)NC[C@H](O)C=1C=C(Cl)C=CC=1)C1=CC=C(OCC(O)=O)C=C1 ZGGNJJJYUVRADP-ACJLOTCBSA-N 0.000 claims 1
- VMMYRRFPMAGXNP-BTYIYWSLSA-N 2-[4-[2-[[(1r,2s)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]-2,5-dimethylphenoxy]acetic acid Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC(C)=C(OCC(O)=O)C=C1C VMMYRRFPMAGXNP-BTYIYWSLSA-N 0.000 claims 1
- HUUHHWPSOFUOEV-UHFFFAOYSA-N 3-methyl-4-(5-oxo-3-phenylimidazolidin-1-yl)benzenesulfonamide Chemical compound CC1=CC(S(N)(=O)=O)=CC=C1N1C(=O)CN(C=2C=CC=CC=2)C1 HUUHHWPSOFUOEV-UHFFFAOYSA-N 0.000 claims 1
- IBPCNRNTIRZRJZ-QFIPXVFZSA-N 4-[4-[2-[[(2r)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethyl]phenyl]-2-methoxybenzoic acid Chemical compound C1=C(C(O)=O)C(OC)=CC(C=2C=CC(CCNC[C@H](O)C=3C=C(Cl)C=CC=3)=CC=2)=C1 IBPCNRNTIRZRJZ-QFIPXVFZSA-N 0.000 claims 1
- RDJQCOBTKKAQAH-FPOVZHCZSA-N Amibegron Chemical group C1([C@@H](O)CN[C@H]2CCC3=CC=C(C=C3C2)OCC(=O)OCC)=CC=CC(Cl)=C1 RDJQCOBTKKAQAH-FPOVZHCZSA-N 0.000 claims 1
- 239000000048 adrenergic agonist Substances 0.000 claims 1
- 229940126157 adrenergic receptor agonist Drugs 0.000 claims 1
- 229950008231 amibegron Drugs 0.000 claims 1
- FUZBPOHHSBDTJQ-CFOQQKEYSA-L disodium;5-[(2r)-2-[[(2r)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate Chemical compound [Na+].[Na+].C1([C@@H](O)CN[C@@H](CC=2C=C3OC(OC3=CC=2)(C([O-])=O)C([O-])=O)C)=CC=CC(Cl)=C1 FUZBPOHHSBDTJQ-CFOQQKEYSA-L 0.000 claims 1
- 229950003058 fasobegron Drugs 0.000 claims 1
- 210000002850 nasal mucosa Anatomy 0.000 claims 1
- 230000001766 physiological effect Effects 0.000 claims 1
- 229950008844 ritobegron Drugs 0.000 claims 1
- 229940126158 β3 adrenergic receptor agonist Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361857431P | 2013-07-23 | 2013-07-23 | |
| US61/857,431 | 2013-07-23 | ||
| PCT/US2014/047899 WO2015013454A1 (en) | 2013-07-23 | 2014-07-23 | Methods and compositions comprising desmopressin in combination with a beta-3 adrenergic receptor agonist |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020065913A Division JP7219736B2 (ja) | 2013-07-23 | 2020-04-01 | Β－３アドレナリン受容体刺激薬と組み合わせたデスモプレシンを含む方法及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016525548A JP2016525548A (ja) | 2016-08-25 |
| JP2016525548A5 true JP2016525548A5 (cg-RX-API-DMAC7.html) | 2017-08-31 |
Family
ID=51299056
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016529872A Pending JP2016525548A (ja) | 2013-07-23 | 2014-07-23 | Β−３アドレナリン受容体刺激薬と組み合わせたデスモプレシンを含む方法及び組成物 |
| JP2020065913A Active JP7219736B2 (ja) | 2013-07-23 | 2020-04-01 | Β－３アドレナリン受容体刺激薬と組み合わせたデスモプレシンを含む方法及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020065913A Active JP7219736B2 (ja) | 2013-07-23 | 2020-04-01 | Β－３アドレナリン受容体刺激薬と組み合わせたデスモプレシンを含む方法及び組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9814753B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3024474B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2016525548A (cg-RX-API-DMAC7.html) |
| KR (3) | KR20160033220A (cg-RX-API-DMAC7.html) |
| CN (1) | CN105579057A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2014293141A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2919198A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3024474T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2910361T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2016001030A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015013454A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0623838D0 (en) * | 2006-11-29 | 2007-01-10 | Malvern Cosmeceutics Ltd | Novel compositions |
| PT4104848T (pt) | 2009-06-18 | 2024-01-04 | Acerus Pharmaceuticals Usa Llc | Administração segura de desmopressina |
| US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
| CN105579057A (zh) | 2013-07-23 | 2016-05-11 | 阿勒根公司 | 包含与β-3-肾上腺素能受体激动剂组合的去氨加压素的方法和组合物 |
| JP2016525147A (ja) | 2013-07-23 | 2016-08-22 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | ５−α還元酵素阻害剤と組み合わせたデスモプレシンを含む方法及び組成物 |
| KR20170097045A (ko) | 2014-11-20 | 2017-08-25 | 알레간 인코포레이티드 | 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물 |
| CA2969405A1 (en) | 2014-12-03 | 2016-06-09 | Velicept Therapeutics, Inc. | Compositions and methods of using modified release solabegron for lower urinary tract symptoms |
| US20170348263A1 (en) * | 2016-06-03 | 2017-12-07 | Velicept Therapeutics, Inc. | Compositions and methods of using modified release solabegron for lower urinary tract symptoms |
| KR101877834B1 (ko) * | 2017-04-27 | 2018-07-12 | 주식회사 다산제약 | 미라베그론의 신규한 염 및 이의 제조방법 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH495957A (de) | 1966-09-15 | 1970-09-15 | Ceskoslovenska Akademie Ved | Verfahren zur Herstellung eines antidiuretisch wirksamen Polypeptids |
| US3989816A (en) | 1975-06-19 | 1976-11-02 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacycloheptan-2-ones |
| US4316893A (en) | 1975-06-19 | 1982-02-23 | Nelson Research & Development Co. | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
| US4405616A (en) | 1975-06-19 | 1983-09-20 | Nelson Research & Development Company | Penetration enhancers for transdermal drug delivery of systemic agents |
| US4557934A (en) | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US4783450A (en) | 1987-04-13 | 1988-11-08 | Warner-Lambert Company | Use of commercial lecithin as skin penetration enhancer |
| NZ241979A (en) | 1991-03-20 | 1996-01-26 | Merck & Co Inc | Treatment of benign prostatic hyperplasia using 5alpha-reductase inhibitor and an alpha1-adrenergic recepter blocker |
| US5534496A (en) | 1992-07-07 | 1996-07-09 | University Of Southern California | Methods and compositions to enhance epithelial drug transport |
| ES2249846T3 (es) | 1997-12-02 | 2006-04-01 | Archimedes Development Limited | Composiciones para administracion nasal. |
| US7335186B2 (en) | 1998-03-13 | 2008-02-26 | Alexander George Brian O'Neil | Patient controlled drug delivery device |
| US6558695B2 (en) | 1999-12-16 | 2003-05-06 | Dermatrends, Inc. | Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers |
| ES2717656T3 (es) | 2000-11-30 | 2019-06-24 | Valeritas Inc | Dispositivo con microsonda amovible sustancialmente libre sobre el alojamiento |
| US7244703B2 (en) | 2001-06-22 | 2007-07-17 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for peptide treatment |
| GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| US6945952B2 (en) | 2002-06-25 | 2005-09-20 | Theraject, Inc. | Solid solution perforator for drug delivery and other applications |
| ATE500827T1 (de) * | 2002-11-07 | 2011-03-15 | Astellas Pharma Inc | Mittel zur behandlung von blasenhyperaktivität mit einem essigsäureanilid-derivat als wirkstoff |
| CA2866501A1 (en) * | 2003-11-10 | 2005-05-26 | Allergan, Inc. | Pharmaceutical compositions including low dosages of desmopressin |
| CA2547990C (en) | 2003-12-08 | 2011-08-02 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for insulin treatment |
| DE102005016981A1 (de) | 2005-04-13 | 2006-10-19 | Bayer Healthcare Ag | Kombination zur Therapie bei benigner Prostatahyperplasie |
| CA2633570A1 (en) | 2005-12-21 | 2007-06-28 | Pfizer Products Inc. | Pharmaceutical combination of a pde-5 inhibitor and a 5-alpha reductase inhibitor |
| WO2007083640A1 (ja) * | 2006-01-18 | 2007-07-26 | Kyorin Pharmaceutical Co., Ltd. | 頻尿及び尿失禁の予防又は治療剤 |
| CA2988753A1 (en) * | 2007-08-06 | 2009-02-12 | Serenity Pharmaceuticals, Llc | Methods and devices for desmopressin drug delivery |
| CN101648017A (zh) | 2008-08-12 | 2010-02-17 | 许洁 | 用于治疗泌尿生殖系统及下尿路疾病的联合药物组合物 |
| US20110144055A1 (en) | 2008-09-04 | 2011-06-16 | Rozmanith Anthony I | Health Care |
| BRPI0923557A2 (pt) | 2008-12-22 | 2016-01-26 | Allergan Inc | administração de desmopressina intranasal |
| WO2010075327A1 (en) | 2008-12-22 | 2010-07-01 | Serenity Pharmaceuticals Corporation | Desmopressin composition |
| PT4104848T (pt) * | 2009-06-18 | 2024-01-04 | Acerus Pharmaceuticals Usa Llc | Administração segura de desmopressina |
| KR20120093859A (ko) * | 2009-10-07 | 2012-08-23 | 머크 샤프 앤드 돔 코포레이션 | 베타 ３ 아드레날린 수용체 효능제 및 항무스카린제를 사용하는 조합 요법 |
| US9119878B2 (en) | 2010-07-08 | 2015-09-01 | Wellesley Pharmaceuticals, Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| US9522129B2 (en) * | 2010-08-03 | 2016-12-20 | Velicept Therapeutics, Inc. | Pharmaceutical Combination |
| WO2012109387A1 (en) | 2011-02-08 | 2012-08-16 | Halozyme, Inc. | Composition and lipid formulation of a hyaluronan-degrading enzyme and the use thereof for treatment of benign prostatic hyperplasia |
| MX2014011128A (es) | 2012-03-19 | 2015-08-10 | Wellesley Pharmaceuticals Llc | Formulacion de liberacion prolongada para reducir la frecuencia de miccion y metodo de uso de la misma. |
| TW201422254A (zh) | 2012-11-21 | 2014-06-16 | Ferring Bv | 用於速釋及延釋的組成物 |
| GB201312155D0 (en) | 2013-07-05 | 2013-08-21 | Ucl Business Plc | Therapeutic invention |
| JP2016525147A (ja) | 2013-07-23 | 2016-08-22 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | ５−α還元酵素阻害剤と組み合わせたデスモプレシンを含む方法及び組成物 |
| CN105579057A (zh) | 2013-07-23 | 2016-05-11 | 阿勒根公司 | 包含与β-3-肾上腺素能受体激动剂组合的去氨加压素的方法和组合物 |
| MX2016002705A (es) | 2013-09-03 | 2016-09-06 | G2B Pharma Inc | Formulacion intranasal para el tratamiento por reanimacion cardiopulmonar (rcp), mantenimiento cardiaco vital (cls), de anafilaxia y/o reacciones anafilactoides. |
| KR20170097045A (ko) | 2014-11-20 | 2017-08-25 | 알레간 인코포레이티드 | 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물 |
-
2014
- 2014-07-23 CN CN201480052301.7A patent/CN105579057A/zh active Pending
- 2014-07-23 CA CA2919198A patent/CA2919198A1/en active Pending
- 2014-07-23 KR KR1020167004515A patent/KR20160033220A/ko not_active Ceased
- 2014-07-23 MX MX2016001030A patent/MX2016001030A/es unknown
- 2014-07-23 EP EP14748451.3A patent/EP3024474B1/en active Active
- 2014-07-23 KR KR1020217025792A patent/KR20210103589A/ko not_active Ceased
- 2014-07-23 DK DK14748451.3T patent/DK3024474T3/da active
- 2014-07-23 JP JP2016529872A patent/JP2016525548A/ja active Pending
- 2014-07-23 AU AU2014293141A patent/AU2014293141A1/en not_active Abandoned
- 2014-07-23 US US14/338,554 patent/US9814753B2/en not_active Expired - Fee Related
- 2014-07-23 WO PCT/US2014/047899 patent/WO2015013454A1/en not_active Ceased
- 2014-07-23 ES ES14748451T patent/ES2910361T3/es active Active
- 2014-07-23 KR KR1020247002750A patent/KR20240015735A/ko not_active Ceased
-
2017
- 2017-11-13 US US15/811,384 patent/US10568927B2/en active Active
-
2020
- 2020-04-01 JP JP2020065913A patent/JP7219736B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016525548A5 (cg-RX-API-DMAC7.html) | ||
| EA201270221A1 (ru) | Лечение болезни крона с применением лаквинимода | |
| EP2248519A3 (en) | Non-mucoadhesive film dosage forms | |
| JP2013121983A5 (cg-RX-API-DMAC7.html) | ||
| FI3936130T3 (fi) | Valbenatsiinin annostusohjelma hyperkineettisten liikehäiriöiden hoitoon | |
| JP2016185995A5 (cg-RX-API-DMAC7.html) | ||
| HRP20161444T1 (hr) | Farmaceutski pripravci koji sadrže lokalni anestetik kao što je bupivakain za lokalnu primjenu u usta ili grlo | |
| BRPI0806392A8 (pt) | uso de aclidínio, aclidínio, método de tratamento ou prevenção e composição farmacêutica | |
| JP2017506624A5 (cg-RX-API-DMAC7.html) | ||
| JP2016539921A5 (cg-RX-API-DMAC7.html) | ||
| RU2018136580A (ru) | Цитратная соль (s)-4-((s)-3-фтор-3-(2-(5,6,7,8-тетрагидро-1,8-нафтиридин-2-ил)этил)пирролидин-1-ил)-3-(3-(2-метоксиэтокси)фенил)бутановой кислоты | |
| JP2016519107A5 (cg-RX-API-DMAC7.html) | ||
| JP2019514990A5 (cg-RX-API-DMAC7.html) | ||
| JP2013520448A5 (cg-RX-API-DMAC7.html) | ||
| JP2016505050A5 (cg-RX-API-DMAC7.html) | ||
| HRP20211488T1 (hr) | Sastav i metoda za liječenje metaboličkih poremećaja | |
| JP2014520874A5 (cg-RX-API-DMAC7.html) | ||
| JP2020500930A5 (cg-RX-API-DMAC7.html) | ||
| MX2018013475A (es) | Acido carboxilico para tratar/prevenir congestion nasal. | |
| JP7369523B2 (ja) | 中等度～重度のインフルエンザの処置 | |
| KR101896441B1 (ko) | 국소투여형의 연하장애 개선용 의약품 | |
| JP2016504361A5 (cg-RX-API-DMAC7.html) | ||
| JP2016525147A5 (cg-RX-API-DMAC7.html) | ||
| JP2017513866A5 (cg-RX-API-DMAC7.html) | ||
| MX2018011293A (es) | Composicion farmaceutica de liberacion prolongada que comprende cisteamina o sal de la misma. |