|
US7901708B2
(en)
|
2002-06-28 |
2011-03-08 |
Protiva Biotherapeutics, Inc. |
Liposomal apparatus and manufacturing methods
|
|
EP3403647A1
(en)
|
2009-12-01 |
2018-11-21 |
Translate Bio, Inc. |
Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
|
|
WO2012000104A1
(en)
|
2010-06-30 |
2012-01-05 |
Protiva Biotherapeutics, Inc. |
Non-liposomal systems for nucleic acid delivery
|
|
US8853377B2
(en)
|
2010-11-30 |
2014-10-07 |
Shire Human Genetic Therapies, Inc. |
mRNA for use in treatment of human genetic diseases
|
|
US20140206753A1
(en)
|
2011-06-08 |
2014-07-24 |
Shire Human Genetic Therapies, Inc. |
Lipid nanoparticle compositions and methods for mrna delivery
|
|
CA3198966A1
(en)
|
2011-06-08 |
2012-12-13 |
Translate Bio, Inc. |
Cleavable lipids
|
|
WO2013126803A1
(en)
|
2012-02-24 |
2013-08-29 |
Protiva Biotherapeutics Inc. |
Trialkyl cationic lipids and methods of use thereof
|
|
ES2762873T3
(es)
|
2012-03-29 |
2020-05-26 |
Translate Bio Inc |
Lípidos catiónicos ionizables
|
|
EP2830596B1
(en)
|
2012-03-29 |
2020-12-30 |
Translate Bio, Inc. |
Lipid-derived neutral nanoparticles
|
|
MX2014015041A
(es)
|
2012-06-08 |
2015-06-17 |
Shire Human Genetic Therapies |
Administración pulmonar de arnm a células objetivo no pulmonares.
|
|
EP2859102A4
(en)
|
2012-06-08 |
2016-05-11 |
Shire Human Genetic Therapies |
NUCLEASE RESISTANT POLYNUCLEOTIDES AND USES THEREOF
|
|
ES2981185T3
(es)
|
2013-03-14 |
2024-10-07 |
Translate Bio Inc |
Métodos para la purificación de ARN mensajero
|
|
LT2970456T
(lt)
|
2013-03-14 |
2021-08-10 |
Translate Bio, Inc. |
Būdai ir kompozicijos, skirti mrnr koduojamų antikūnų pristatymui
|
|
CA2904151C
(en)
|
2013-03-14 |
2023-09-12 |
Shire Human Genetic Therapies, Inc. |
Cftr mrna compositions and related methods and uses
|
|
PL4332576T3
(pl)
|
2013-03-15 |
2025-09-08 |
Translate Bio, Inc. |
Synergistyczne wzmocnienie dostarczania kwasów nukleinowych poprzez formulacje zmieszane
|
|
JP6620093B2
(ja)
*
|
2013-07-23 |
2019-12-11 |
アービュートゥス バイオファーマ コーポレイションＡｒｂｕｔｕｓ Ｂｉｏｐｈａｒｍａ Ｃｏｒｐｏｒａｔｉｏｎ |
メッセンジャーｒｎａを送達するための組成物及び方法
|
|
EA201690675A1
(ru)
|
2013-10-03 |
2016-08-31 |
Модерна Терапьютикс, Инк. |
Полинуклеотиды, кодирующие рецептор липопротеинов низкой плотности
|
|
WO2015061491A1
(en)
|
2013-10-22 |
2015-04-30 |
Shire Human Genetic Therapies, Inc. |
Mrna therapy for phenylketonuria
|
|
US20150110857A1
(en)
|
2013-10-22 |
2015-04-23 |
Shire Human Genetic Therapies, Inc. |
Cns delivery of mrna and uses thereof
|
|
MX2016005238A
(es)
|
2013-10-22 |
2016-08-12 |
Shire Human Genetic Therapies |
Formulaciones de lipidos para la administracion de acido ribonucleico mensajero.
|
|
BR112016009014B1
(pt)
|
2013-10-22 |
2024-02-06 |
Translate Bio, Inc |
USO DE COMPOSIÇÃO COMPREENDENDO mRNA PARA DEFICIÊNCIA DE ARGININOSSUCINATO SINTETASE
|
|
DK4023249T3
(da)
|
2014-04-23 |
2025-01-13 |
Modernatx Inc |
Nukleinsyrevacciner
|
|
MX373952B
(es)
|
2014-04-25 |
2020-07-13 |
Shire Human Genetic Therapies |
Métodos de purificación de arn mensajero.
|
|
CN106659731A
(zh)
|
2014-05-30 |
2017-05-10 |
夏尔人类遗传性治疗公司 |
用于递送核酸的可生物降解脂质
|
|
UA121863C2
(uk)
|
2014-06-24 |
2020-08-10 |
Транслейт Байо, Інк. |
Стереохімічно збагачені композиції для доставки нуклеїнових кислот
|
|
EP3164112A1
(en)
|
2014-07-02 |
2017-05-10 |
Shire Human Genetic Therapies, Inc. |
Encapsulation of messenger rna
|
|
WO2016090262A1
(en)
|
2014-12-05 |
2016-06-09 |
Shire Human Genetic Therapies, Inc. |
Messenger rna therapy for treatment of articular disease
|
|
CA2979695C
(en)
|
2015-03-19 |
2025-02-06 |
Translate Bio Inc |
RNA THERAPY FOR POMPE DISEASE
|
|
WO2016165825A1
(en)
|
2015-04-13 |
2016-10-20 |
Curevac Ag |
Method for producing rna compositions
|
|
WO2016197132A1
(en)
*
|
2015-06-04 |
2016-12-08 |
Protiva Biotherapeutics Inc. |
Treating hepatitis b virus infection using crispr
|
|
WO2016197133A1
(en)
*
|
2015-06-04 |
2016-12-08 |
Protiva Biotherapeutics, Inc. |
Delivering crispr therapeutics with lipid nanoparticles
|
|
WO2017019935A1
(en)
*
|
2015-07-30 |
2017-02-02 |
Modernatx, Inc. |
Multimeric mrna
|
|
US11564893B2
(en)
|
2015-08-17 |
2023-01-31 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
|
DK3350157T3
(da)
|
2015-09-17 |
2022-02-14 |
Modernatx Inc |
Forbindelser og sammensætninger til intracellulær afgivelse af terapeutiske midler
|
|
CA3001852A1
(en)
|
2015-10-14 |
2017-04-20 |
Translate Bio, Inc. |
Modification of rna-related enzymes for enhanced production
|
|
MX391259B
(es)
|
2015-10-14 |
2025-03-21 |
X Therma Inc |
Composiciones y métodos para reducir la formación de cristales de hielo.
|
|
MA46316A
(fr)
|
2015-10-22 |
2021-03-24 |
Modernatx Inc |
Vaccin contre le cytomégalovirus humain
|
|
AU2016377681B2
(en)
|
2015-12-22 |
2021-05-13 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of agents
|
|
JP7150608B6
(ja)
|
2016-04-08 |
2022-11-11 |
トランスレイト バイオ， インコーポレイテッド |
多量体コード核酸及びその使用
|
|
US20190167811A1
(en)
|
2016-04-13 |
2019-06-06 |
Modernatx, Inc. |
Lipid compositions and their uses for intratumoral polynucleotide delivery
|
|
CN109414451B
(zh)
*
|
2016-05-16 |
2022-08-12 |
德克萨斯大学系统董事会 |
用于作为纳米粒递送tRNA的组合物及其使用方法
|
|
JP2019522047A
(ja)
|
2016-06-13 |
2019-08-08 |
トランスレイト バイオ， インコーポレイテッド |
オルニチントランスカルバミラーゼ欠損症治療のためのメッセンジャーｒｎａ療法
|
|
EP3478838A1
(en)
*
|
2016-06-30 |
2019-05-08 |
Arbutus Biopharma Corporation |
Compositions and methods for delivering messenger rna
|
|
KR20190026819A
(ko)
|
2016-07-07 |
2019-03-13 |
루비우스 테라퓨틱스, 아이엔씨. |
외인성 rna를 발현하는 치료용 세포 시스템과 관련된 조성물 및 방법
|
|
WO2018075980A1
(en)
|
2016-10-21 |
2018-04-26 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
US12491261B2
(en)
|
2016-10-26 |
2025-12-09 |
Acuitas Therapeutics, Inc. |
Lipid nanoparticle formulations
|
|
US11583504B2
(en)
|
2016-11-08 |
2023-02-21 |
Modernatx, Inc. |
Stabilized formulations of lipid nanoparticles
|
|
SG11201906744VA
(en)
*
|
2017-01-27 |
2019-08-27 |
Methodist Hospital |
Core/shell structure platform for immunotherapy
|
|
MX2019010155A
(es)
|
2017-02-27 |
2020-12-10 |
Translate Bio Inc |
Arnm de cftr optimizado por codón novedoso.
|
|
CA3055653A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Lipid nanoparticle formulation
|
|
EP3595713A4
(en)
|
2017-03-15 |
2021-01-13 |
ModernaTX, Inc. |
Respiratory syncytial virus vaccine
|
|
AU2018234692B2
(en)
|
2017-03-15 |
2022-06-02 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
|
ES2911186T3
(es)
*
|
2017-03-15 |
2022-05-18 |
Modernatx Inc |
Formas cristalinas de aminolípidos
|
|
MA49138A
(fr)
|
2017-05-16 |
2020-03-25 |
Translate Bio Inc |
Traitement de la fibrose kystique par administration d'arnm à codons optimisés codant pour la cftr
|
|
WO2018213731A1
(en)
|
2017-05-18 |
2018-11-22 |
Modernatx, Inc. |
Polynucleotides encoding tethered interleukin-12 (il12) polypeptides and uses thereof
|
|
WO2018232120A1
(en)
|
2017-06-14 |
2018-12-20 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of agents
|
|
EP3638292A1
(en)
|
2017-06-14 |
2020-04-22 |
ModernaTX, Inc. |
Polynucleotides encoding coagulation factor viii
|
|
US11786607B2
(en)
|
2017-06-15 |
2023-10-17 |
Modernatx, Inc. |
RNA formulations
|
|
US20190046649A1
(en)
*
|
2017-08-09 |
2019-02-14 |
University Of Maryland, Baltimore County |
Delivery device and use thereof for loading cell plasma membranes
|
|
WO2019040516A1
(en)
|
2017-08-22 |
2019-02-28 |
Rubius Therapeutics, Inc. |
METHODS AND COMPOSITIONS OF LIPID NANOPARTICLES FOR THE PRODUCTION OF MODIFIED ERYTHROID CELLS
|
|
MX2020002348A
(es)
|
2017-08-31 |
2020-10-08 |
Modernatx Inc |
Métodos de elaboración de nanopartículas lipídicas.
|
|
CA3084061A1
(en)
|
2017-12-20 |
2019-06-27 |
Translate Bio, Inc. |
Improved composition and methods for treatment of ornithine transcarbamylase deficiency
|
|
TWI894123B
(zh)
*
|
2017-12-27 |
2025-08-21 |
日商武田藥品工業有限公司 |
含核酸之脂質奈米粒子及其用途
|
|
US20190330591A1
(en)
|
2018-01-10 |
2019-10-31 |
Rubius Therapeutics, Inc. |
Amplifiable rnas for therapeutic cell systems
|
|
US11911453B2
(en)
|
2018-01-29 |
2024-02-27 |
Modernatx, Inc. |
RSV RNA vaccines
|
|
WO2020041793A1
(en)
|
2018-08-24 |
2020-02-27 |
Translate Bio, Inc. |
Methods for purification of messenger rna
|
|
US12263248B2
(en)
|
2018-09-19 |
2025-04-01 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
|
US12090235B2
(en)
|
2018-09-20 |
2024-09-17 |
Modernatx, Inc. |
Preparation of lipid nanoparticles and methods of administration thereof
|
|
JP7387745B2
(ja)
*
|
2018-10-01 |
2023-11-28 |
アルニラム・ファーマシューティカルズ・インコーポレーテッド |
活性物質の送達のための生分解性脂質
|
|
KR20210093232A
(ko)
|
2018-10-09 |
2021-07-27 |
더 유니버시티 오브 브리티시 콜롬비아 |
유기용매와 세제가 없는 형질감염 적격 소포를 포함하는 조성물과 시스템 및 관련 방법
|
|
MX2021004357A
(es)
|
2018-10-18 |
2021-05-31 |
Takeda Pharmaceuticals Co |
Metodo para la activacion y proliferacion de las celulas t.
|
|
AU2019362031A1
(en)
*
|
2018-10-19 |
2021-04-08 |
Translate Bio, Inc. |
Pumpless encapsulation of messenger RNA
|
|
CN113728101A
(zh)
*
|
2018-11-09 |
2021-11-30 |
阿布特斯生物制药公司 |
脂质纳米颗粒制剂
|
|
EP3877521A4
(en)
*
|
2018-11-09 |
2022-07-27 |
Arbutus Biopharma Corporation |
Lipid nanoparticle formulations
|
|
AU2019384557B2
(en)
|
2018-11-21 |
2025-07-17 |
Translate Bio, Inc. |
Treatment of cystic fibrosis by delivery of nebulized mRNA encoding CFTR
|
|
MA55321A
(fr)
|
2019-03-15 |
2022-01-19 |
Modernatx Inc |
Vaccins à base d'arn contre le vih
|
|
EP3999642A1
(en)
|
2019-07-19 |
2022-05-25 |
Flagship Pioneering Innovations VI, LLC |
Recombinase compositions and methods of use
|
|
HUE068356T2
(hu)
*
|
2019-08-14 |
2024-12-28 |
Acuitas Therapeutics Inc |
Javított lipid nanorészecskék nukleinsavak bejuttatására
|
|
KR20220103923A
(ko)
*
|
2019-09-19 |
2022-07-25 |
모더나티엑스, 인크. |
치료제의 세포내 전달을 위한 신규한 헤드기 지질 화합물 및 조성물
|
|
CA3154618A1
(en)
|
2019-09-19 |
2021-03-25 |
Modernatx, Inc. |
Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents
|
|
US20220396556A1
(en)
*
|
2019-10-18 |
2022-12-15 |
The Trustees Of The University Of Pennsylvania |
Lipid and Lipid Nanoparticle Formulation for Drug Delivery
|
|
JP7709981B2
(ja)
|
2020-03-17 |
2025-07-17 |
ジェネヴァント サイエンシズ ゲーエムベーハー |
肝星細胞への治療薬の脂質ナノ粒子送達のためのカチオン性脂質
|
|
MX2022011806A
(es)
|
2020-03-24 |
2023-01-11 |
Generation Bio Co |
Vectores de adn no virales y usos de estos para expresar agentes terapéuticos contra gaucher.
|
|
JP2023520764A
(ja)
|
2020-03-24 |
2023-05-19 |
ジェネレーション バイオ カンパニー |
第ｉｘ因子治療薬を発現するための非ウイルス性ｄｎａベクター及びその使用
|
|
CN117003658B
(zh)
|
2020-04-09 |
2025-10-14 |
苏州艾博生物科技有限公司 |
脂质纳米颗粒组合物
|
|
TW202204622A
(zh)
|
2020-04-09 |
2022-02-01 |
大陸商蘇州艾博生物科技有限公司 |
針對冠狀病毒之核酸疫苗
|
|
AU2021275213A1
(en)
|
2020-05-20 |
2023-02-02 |
Flagship Pioneering Innovations Vi, Llc |
Immunogenic compositions and uses thereof
|
|
IL298362A
(en)
|
2020-05-20 |
2023-01-01 |
Flagship Pioneering Innovations Vi Llc |
Coronavirus antigen compositions and their uses
|
|
AU2021281453A1
(en)
|
2020-05-29 |
2022-11-17 |
Flagship Pioneering Innovations Vi, Llc. |
Trem compositions and methods relating thereto
|
|
CA3180101A1
(en)
|
2020-05-29 |
2021-12-02 |
Flagship Pioneering Innovations Vi, Llc |
Trem compositions and methods relating thereto
|
|
CA3182994A1
(en)
|
2020-06-30 |
2022-01-06 |
Bo YING |
Lipid compounds and lipid nanoparticle compositions
|
|
MX2023000614A
(es)
|
2020-07-16 |
2023-02-13 |
Acuitas Therapeutics Inc |
Lipidos cationicos para usarse en nanoparticulas lipidicas.
|
|
WO2022040310A2
(en)
*
|
2020-08-18 |
2022-02-24 |
Ohio State Innovation Foundation |
Bioinspired lipid derivatives and uses thereof
|
|
JP2023537887A
(ja)
|
2020-08-20 |
2023-09-06 |
スージョウ・アボジェン・バイオサイエンシズ・カンパニー・リミテッド |
脂質化合物及び脂質ナノ粒子組成物
|
|
US11406703B2
(en)
|
2020-08-25 |
2022-08-09 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
WO2022051629A1
(en)
|
2020-09-03 |
2022-03-10 |
Flagship Pioneering Innovations Vi, Llc |
Immunogenic compositions and uses thereof
|
|
US20220218622A1
(en)
|
2020-10-14 |
2022-07-14 |
George Mason Research Foundation, Inc. |
Ionizable lipids and methods of manufacture and use thereof
|
|
WO2022099003A1
(en)
|
2020-11-06 |
2022-05-12 |
Sanofi |
Lipid nanoparticles for delivering mrna vaccines
|
|
PH12023500013A1
(en)
*
|
2020-12-04 |
2024-03-11 |
Tidal Therapeutics Inc |
Ionizable cationic lipids and lipi nanoparticles, and methods of synthesis and use thereof
|
|
US20240148663A1
(en)
|
2020-12-18 |
2024-05-09 |
Genevant Sciences Gmbh |
Peg lipids and lipid nanoparticles
|
|
JP2024501288A
(ja)
|
2020-12-23 |
2024-01-11 |
フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー |
修飾ｔｒｅｍの組成物及びその使用
|
|
CN116615472A
(zh)
|
2021-01-14 |
2023-08-18 |
苏州艾博生物科技有限公司 |
聚合物缀合的脂质化合物和脂质纳米颗粒组合物
|
|
WO2022152109A2
(en)
|
2021-01-14 |
2022-07-21 |
Suzhou Abogen Biosciences Co., Ltd. |
Lipid compounds and lipid nanoparticle compositions
|
|
US12036286B2
(en)
|
2021-03-18 |
2024-07-16 |
Seagen Inc. |
Selective drug release from internalized conjugates of biologically active compounds
|
|
CA3214085A1
(en)
|
2021-03-31 |
2022-10-06 |
Darby Rye Schmidt |
Thanotransmission polypeptides and their use in treating cancer
|
|
EP4329884A1
(en)
|
2021-04-27 |
2024-03-06 |
Generation Bio Co. |
Non-viral dna vectors expressing anti-coronavirus antibodies and uses thereof
|
|
AU2022264509A1
(en)
|
2021-04-27 |
2023-12-14 |
Generation Bio Co. |
Non-viral dna vectors expressing therapeutic antibodies and uses thereof
|
|
US20220389422A1
(en)
*
|
2021-05-06 |
2022-12-08 |
Arcturus Therapeutics, Inc. |
Ionizable cationic lipids for rna delivery
|
|
KR20240013087A
(ko)
|
2021-05-24 |
2024-01-30 |
쑤저우 아보젠 바이오사이언시스 컴퍼니 리미티드 |
지질 화합물 및 지질 나노입자 조성물
|
|
EP4377457A1
(en)
|
2021-07-26 |
2024-06-05 |
Flagship Pioneering Innovations VI, LLC |
Trem compositions and uses thereof
|
|
EP4271818B1
(en)
|
2021-09-17 |
2024-07-31 |
Flagship Pioneering Innovations VI, LLC |
Compositions and methods for producing circular polyribonucleotides
|
|
AU2022358824A1
(en)
|
2021-10-08 |
2024-04-11 |
Suzhou Abogen Biosciences Co., Ltd. |
Lipid compounds and lipid nanoparticle compositions
|
|
CN116064598B
(zh)
|
2021-10-08 |
2024-03-12 |
苏州艾博生物科技有限公司 |
冠状病毒的核酸疫苗
|
|
AR127312A1
(es)
|
2021-10-08 |
2024-01-10 |
Suzhou Abogen Biosciences Co Ltd |
Compuestos lipídicos ycomposiciones de nanopartículas lipídicas
|
|
TW202322826A
(zh)
|
2021-10-18 |
2023-06-16 |
美商旗艦先鋒創新有限責任公司 |
用於純化多核糖核苷酸之組成物及方法
|
|
WO2023081526A1
(en)
|
2021-11-08 |
2023-05-11 |
Orna Therapeutics, Inc. |
Lipid nanoparticle compositions for delivering circular polynucleotides
|
|
US20250352638A1
(en)
|
2021-11-24 |
2025-11-20 |
Flagship Pioneering Innovations Vi, Llc |
Coronavirus immunogen compositions and their uses
|
|
CA3238370A1
(en)
|
2021-11-24 |
2023-06-01 |
Flagship Pioneering Innovations Vi, Llc |
Varicella-zoster virus immunogen compositions and their uses
|
|
MX2024006440A
(es)
|
2021-11-24 |
2024-08-19 |
Flagship Pioneering Innovations Vi Llc |
Composiciones inmunogenicas y sus usos.
|
|
WO2023115013A1
(en)
|
2021-12-17 |
2023-06-22 |
Flagship Pioneering Innovations Vi, Llc |
Methods for enrichment of circular rna under denaturing conditions
|
|
JP2025500360A
(ja)
|
2021-12-22 |
2025-01-09 |
フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー |
ポリリボヌクレオチドを精製するための組成物及び方法
|
|
IL313714A
(en)
|
2021-12-23 |
2024-08-01 |
Flagship Pioneering Innovations Vi Llc |
Cyclic polyribonucleotides encoding antifusogenic polypeptides
|
|
US20250108007A1
(en)
|
2021-12-23 |
2025-04-03 |
Suzhou Abogen Biosciences Co., Ltd. |
Lipid compound and lipid nanoparticle composition
|
|
CN114409554A
(zh)
*
|
2022-01-27 |
2022-04-29 |
英维沃生物科技(苏州)有限公司 |
一种新型阳离子脂质化合物及其组合物和用途
|
|
EP4466250B1
(en)
|
2022-01-31 |
2025-03-26 |
Genevant Sciences Gmbh |
Ionizable cationic lipids for lipid nanoparticles
|
|
KR20240161965A
(ko)
|
2022-03-14 |
2024-11-13 |
제너레이션 바이오 컴퍼니 |
이종 프라임 부스트 백신 조성물 및 사용 방법
|
|
CN119072464A
(zh)
|
2022-03-25 |
2024-12-03 |
赛欧生物医药股份有限公司 |
新型可电离脂质和脂质纳米颗粒以及其使用方法
|
|
JP2025511756A
(ja)
|
2022-04-08 |
2025-04-16 |
フラッグシップ パイオニアリング イノベーションズ セブン，エルエルシー |
ワクチン及び関連する方法
|
|
CN114685784B
(zh)
*
|
2022-04-26 |
2023-09-15 |
北京清科胜因生物科技有限公司 |
一种用于核酸递送的聚(2-噁唑啉)脂质与脂质纳米颗粒及应用
|
|
WO2023220083A1
(en)
|
2022-05-09 |
2023-11-16 |
Flagship Pioneering Innovations Vi, Llc |
Trem compositions and methods of use for treating proliferative disorders
|
|
EP4522753A2
(en)
|
2022-05-13 |
2025-03-19 |
Flagship Pioneering Innovations VII, LLC |
Double stranded dna compositions and related methods
|
|
GB202208022D0
(en)
|
2022-05-31 |
2022-07-13 |
Sisaf Ltd |
Therapeutic compounds and compositions
|
|
EP4536197A1
(en)
|
2022-06-07 |
2025-04-16 |
Generation Bio Co. |
Lipid nanoparticle compositions and uses thereof
|
|
EP4544043A1
(en)
|
2022-06-22 |
2025-04-30 |
Flagship Pioneering Innovations VI, LLC |
Compositions of modified trems and uses thereof
|
|
GB202210794D0
(en)
|
2022-07-22 |
2022-09-07 |
Sisaf Ltd |
Lipid formulations
|
|
CN120129693A
(zh)
|
2022-08-01 |
2025-06-10 |
旗舰创业创新第七有限责任公司 |
免疫调节蛋白及相关方法
|
|
EP4569112A1
(en)
|
2022-08-12 |
2025-06-18 |
Remix Therapeutics Inc. |
Methods and compositions for modulating splicing at alternative splice sites
|
|
WO2024040222A1
(en)
|
2022-08-19 |
2024-02-22 |
Generation Bio Co. |
Cleavable closed-ended dna (cedna) and methods of use thereof
|
|
EP4581012A2
(en)
|
2022-08-31 |
2025-07-09 |
Sail Biomedicines, Inc. |
Novel ionizable lipids and lipid nanoparticles and methods of using the same
|
|
WO2024077191A1
(en)
|
2022-10-05 |
2024-04-11 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer
|
|
AU2023372397A1
(en)
|
2022-10-31 |
2025-05-08 |
Flagship Pioneering Innovations Vi, Llc |
Compositions and methods for purifying polyribonucleotides
|
|
TW202425959A
(zh)
|
2022-11-08 |
2024-07-01 |
美商歐納醫療公司 |
遞送多核苷酸的脂質及奈米顆粒組合物
|
|
TW202428289A
(zh)
|
2022-11-08 |
2024-07-16 |
美商歐納醫療公司 |
環狀rna組合物
|
|
EP4615465A1
(en)
|
2022-11-08 |
2025-09-17 |
Flagship Pioneering Innovations VI, LLC |
Compositions and methods for producing circular polyribonucleotides
|
|
WO2024102762A1
(en)
|
2022-11-08 |
2024-05-16 |
Orna Therapeutics, Inc. |
Lipids and lipid nanoparticle compositions for delivering polynucleotides
|
|
AU2023406303A1
(en)
|
2022-12-01 |
2025-05-29 |
Generation Bio Co. |
Lipid nanoparticles comprising nucleic acids, ionizable lipids, sterols, lipid anchored polymers and helper lipids, their uses
|
|
EP4626402A1
(en)
|
2022-12-01 |
2025-10-08 |
Generation Bio Co. |
Lipid nanoparticles comprising nucleic acids and lipid-anchored polymers
|
|
EP4626401A1
(en)
|
2022-12-01 |
2025-10-08 |
Generation Bio Co. |
Stealth lipid nanoparticle compositions for cell targeting
|
|
AU2023406321A1
(en)
|
2022-12-01 |
2025-05-29 |
Generation Bio Co. |
Novel polyglycerol-conjugated lipids and lipid nanoparticle compositions comprising the same
|
|
EP4630561A1
(en)
|
2022-12-09 |
2025-10-15 |
Takeda Pharmaceutical Company Limited |
Modified immunomodulators
|
|
TW202430215A
(zh)
|
2022-12-14 |
2024-08-01 |
美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 |
用於將治療劑遞送至骨之組成物和方法
|
|
US20240252520A1
(en)
|
2023-01-09 |
2024-08-01 |
Beth Israel Deaconess Medical Center, Inc. |
Therapeutic agents and their use for treating chronic wounds
|
|
TW202438673A
(zh)
|
2023-01-09 |
2024-10-01 |
美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 |
疫苗及相關方法
|
|
WO2024151673A2
(en)
|
2023-01-09 |
2024-07-18 |
President And Fellows Of Harvard College |
Recombinant nucleic acid molecules and their use in wound healing
|
|
WO2024151687A1
(en)
|
2023-01-09 |
2024-07-18 |
Flagship Pioneering Innovations V, Inc. |
Genetic switches and their use in treating cancer
|
|
TW202438515A
(zh)
|
2023-02-06 |
2024-10-01 |
美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 |
免疫調節組合物及相關方法
|
|
US20240293318A1
(en)
|
2023-02-13 |
2024-09-05 |
Flagship Pioneering Innovations Vii, Llc |
Cleavable linker-containing ionizable lipids and lipid carriers for therapeutic compositions
|
|
IL322201A
(en)
|
2023-02-17 |
2025-09-01 |
Flagship Pioneering Innovations Vii Llc |
DNA structures containing modified uracil
|
|
US20240293582A1
(en)
|
2023-02-17 |
2024-09-05 |
Flagship Pioneering Innovations Vii, Llc |
Dna compositions comprising modified cytosine
|
|
KR20250162610A
(ko)
|
2023-03-15 |
2025-11-18 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
폴리리보뉴클레오티드를 포함하는 조성물 및 이의 용도
|
|
WO2024192422A1
(en)
|
2023-03-15 |
2024-09-19 |
Flagship Pioneering Innovations Vi, Llc |
Immunogenic compositions and uses thereof
|
|
WO2024205657A2
(en)
|
2023-03-29 |
2024-10-03 |
Orna Therapeutics, Inc. |
Lipids and lipid nanoparticle compositions for delivering polynucleotides
|
|
WO2024200826A1
(en)
|
2023-03-30 |
2024-10-03 |
Ose Immunotherapeutics |
Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell inhibiting molecule and use thereof
|
|
WO2024200823A1
(en)
|
2023-03-30 |
2024-10-03 |
Ose Immunotherapeutics |
Lipid-based nanoparticle targeted at activated immune cells for the expression of immune cell enhancing molecule and use thereof
|
|
AR132276A1
(es)
|
2023-04-07 |
2025-06-11 |
Takeda Pharmaceuticals Co |
Complejo de conjugación
|
|
AU2024255972A1
(en)
|
2023-04-12 |
2025-10-23 |
Flagship Pioneering Innovations Vi, Llc |
Modified trems, compositions, and related methods thereof
|
|
AU2024252590A1
(en)
|
2023-04-12 |
2025-10-23 |
Flagship Pioneering Innovations Vi, Llc |
Trems for use in correction of missense mutations
|
|
WO2024220746A2
(en)
|
2023-04-21 |
2024-10-24 |
Flagship Pioneering Innovations Vii, Llc |
Rnai agents targeting fatty acid synthase and related methods
|
|
WO2024233308A2
(en)
|
2023-05-05 |
2024-11-14 |
Orna Therapeutics, Inc. |
Circular rna compositions and methods
|
|
WO2024236361A1
(en)
|
2023-05-15 |
2024-11-21 |
Takeda Pharmaceutical Company Limited |
Compositions and methods for delivery of nucleic acids to cells
|
|
WO2024236504A1
(en)
|
2023-05-15 |
2024-11-21 |
Takeda Pharmaceutical Company Limited |
Sequences and methods for delivery of dna and rna
|
|
WO2024258829A1
(en)
|
2023-06-12 |
2024-12-19 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
WO2025006684A1
(en)
|
2023-06-28 |
2025-01-02 |
Flagship Pioneering Innovations Vi, Llc |
Circular polyribonucleotides encoding antifusogenic polypeptides
|
|
WO2025024486A2
(en)
|
2023-07-25 |
2025-01-30 |
Flagship Pioneering Innovations Vii, Llc |
Cas endonucleases and related methods
|
|
WO2025027116A1
(en)
|
2023-08-01 |
2025-02-06 |
Institut Curie |
Nanoparticles comprising nucleic acid sequences encoding cyclic gmp-amp synthase
|
|
WO2025042786A1
(en)
|
2023-08-18 |
2025-02-27 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising circular polyribonucleotides and uses thereof
|
|
WO2025049690A1
(en)
|
2023-08-29 |
2025-03-06 |
Orna Therapeutics, Inc. |
Circular polyethylene glycol lipids
|
|
WO2025052278A1
(en)
|
2023-09-05 |
2025-03-13 |
Genevant Sciences Gmbh |
Pyrrolidine based cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells
|
|
WO2025054236A2
(en)
|
2023-09-06 |
2025-03-13 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
WO2025052180A2
(en)
|
2023-09-07 |
2025-03-13 |
Axelyf ehf. |
Lipids and lipid nanoparticles
|
|
WO2025064475A2
(en)
|
2023-09-18 |
2025-03-27 |
Flagship Pioneering Innovations Vii, Llc |
Ionizable lipidoid compositions and therapeutic uses thereof
|
|
WO2025072331A1
(en)
|
2023-09-26 |
2025-04-03 |
Flagship Pioneering Innovations Vii, Llc |
Cas nucleases and related methods
|
|
WO2025096807A2
(en)
|
2023-10-31 |
2025-05-08 |
Flagship Pioneering Innovations Vii, Llc |
Novel therapeutic dna forms
|
|
WO2025101501A1
(en)
|
2023-11-07 |
2025-05-15 |
Orna Therapeutics, Inc. |
Circular rna compositions
|
|
TW202535835A
(zh)
|
2023-11-14 |
2025-09-16 |
美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 |
可電離類脂質組成物及其治療用途
|
|
TW202523695A
(zh)
|
2023-11-22 |
2025-06-16 |
美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 |
用於治療非酒精性脂肪性肝病之方法及組成物
|
|
WO2025117877A2
(en)
|
2023-12-01 |
2025-06-05 |
Flagship Pioneering Innovations Vii, Llc |
Cas nucleases and related methods
|
|
WO2025133115A1
(en)
|
2023-12-21 |
2025-06-26 |
Ose Immunotherapeutics |
Lipid-based nanoparticles comprising il-35
|
|
US20250375499A1
(en)
|
2024-01-26 |
2025-12-11 |
Flagship Pioneering Innovations Vii, Llc |
Immunoreceptor inhibitory proteins and related methods
|
|
WO2025157978A1
(en)
*
|
2024-01-26 |
2025-07-31 |
Merck Patent Gmbh |
Ionizable lipids for use in lipid nanoparticles
|
|
WO2025194019A1
(en)
|
2024-03-14 |
2025-09-18 |
Flagship Pioneering Innovations Vii, Llc |
Methods for treating liver fibrosis and non-alcoholic fatty liver disease
|
|
WO2025194138A1
(en)
|
2024-03-14 |
2025-09-18 |
Tessera Therapeutics, Inc. |
St1cas9 compositions and methods for modulating a genome
|
|
WO2025217275A2
(en)
|
2024-04-10 |
2025-10-16 |
Flagship Pioneering Innovations Vii, Llc |
Immune cell targeted compositions and related methods
|
|
US20250353881A1
(en)
|
2024-05-16 |
2025-11-20 |
Flagship Pioneering Innovations Vii, Llc |
Immunoreceptor inhibitory proteins and related methods
|
|
WO2025245188A2
(en)
|
2024-05-21 |
2025-11-27 |
Flagship Pioneering Innovations Vii, Llc |
Methods of treating liver steatosis and non-alcoholic fatty liver disease
|
|
WO2025245111A1
(en)
|
2024-05-22 |
2025-11-27 |
Flagship Pioneering Innovations Vii, Llc |
Immunoreceptor targeting proteins and related methods
|