JP2022501064A5 - - Google Patents
Info
- Publication number
- JP2022501064A5 JP2022501064A5 JP2021525114A JP2021525114A JP2022501064A5 JP 2022501064 A5 JP2022501064 A5 JP 2022501064A5 JP 2021525114 A JP2021525114 A JP 2021525114A JP 2021525114 A JP2021525114 A JP 2021525114A JP 2022501064 A5 JP2022501064 A5 JP 2022501064A5
- Authority
- JP
- Japan
- Prior art keywords
- lipid
- mol
- nucleic acid
- particles
- total lipids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024202026A JP2025019119A (ja) | 2018-11-09 | 2024-11-20 | ケイ素を含有するカチオン性脂質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862758108P | 2018-11-09 | 2018-11-09 | |
| US62/758,108 | 2018-11-09 | ||
| PCT/US2019/060556 WO2020097520A1 (en) | 2018-11-09 | 2019-11-08 | Cationic lipids containing silicon |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024202026A Division JP2025019119A (ja) | 2018-11-09 | 2024-11-20 | ケイ素を含有するカチオン性脂質 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022501064A JP2022501064A (ja) | 2022-01-06 |
| JP2022501064A5 true JP2022501064A5 (enExample) | 2022-11-04 |
Family
ID=70612265
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525114A Pending JP2022501064A (ja) | 2018-11-09 | 2019-11-08 | ケイ素を含有するカチオン性脂質 |
| JP2024202026A Pending JP2025019119A (ja) | 2018-11-09 | 2024-11-20 | ケイ素を含有するカチオン性脂質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024202026A Pending JP2025019119A (ja) | 2018-11-09 | 2024-11-20 | ケイ素を含有するカチオン性脂質 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US12350383B2 (enExample) |
| EP (1) | EP3877001A4 (enExample) |
| JP (2) | JP2022501064A (enExample) |
| KR (1) | KR20210105888A (enExample) |
| CN (1) | CN113286622A (enExample) |
| AU (1) | AU2019376006A1 (enExample) |
| BR (1) | BR112021008953A2 (enExample) |
| CA (1) | CA3119051A1 (enExample) |
| EA (1) | EA202191315A1 (enExample) |
| IL (1) | IL282957A (enExample) |
| MX (1) | MX2021005462A (enExample) |
| SG (1) | SG11202104682PA (enExample) |
| WO (1) | WO2020097520A1 (enExample) |
| ZA (1) | ZA202103229B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20240586T1 (hr) | 2018-10-09 | 2024-07-19 | The University Of British Columbia | Sastavi i sustavi koji sadrže transfekcijske sposobne vezikle bez organskih otapala i deterdženta i s njim povezanim postupcima |
| CA3112837A1 (en) * | 2018-10-19 | 2020-04-23 | Translate Bio, Inc. | Pumpless encapsulation of messenger rna |
| CN114729376A (zh) | 2019-09-23 | 2022-07-08 | 欧米茄治疗公司 | 用于调节肝细胞核因子4α(HNF4α)基因表达的组合物和方法 |
| EP4048807A1 (en) | 2019-09-23 | 2022-08-31 | Omega Therapeutics, Inc. | Compositions and methods for modulating apolipoprotein b (apob) gene expression |
| CA3173528A1 (en) | 2020-03-11 | 2021-09-16 | Omega Therapeutics, Inc. | Compositions and methods for modulating forkhead box p3 (foxp3) gene expression |
| WO2022011156A1 (en) * | 2020-07-10 | 2022-01-13 | Genevant Sciences Gmbh | Lipid nanoparticles for delivering therapeutics to lungs |
| CZ310613B6 (cs) | 2020-09-23 | 2026-01-28 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Lipidoidy pro transfekci nukleových kyselin a jejich použití |
| EP4367242A2 (en) | 2021-07-07 | 2024-05-15 | Omega Therapeutics, Inc. | Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression |
| CZ310443B6 (cs) | 2021-07-19 | 2025-06-25 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití |
| EP4716741A2 (en) | 2023-05-23 | 2026-04-01 | Flagship Labs 114, Inc. | Compositions and methods for reducing cxcl9, cxcl10, and cxcl11 gene expression |
| WO2025129128A1 (en) | 2023-12-15 | 2025-06-19 | Vivasor, Inc. | Compositions and methods for non-viral delivery of therapeutic compounds |
| WO2025133951A1 (en) | 2023-12-21 | 2025-06-26 | Genevant Sciences Gmbh | Ionizable lipids suitable for lipid nanoparticles |
| WO2025166325A1 (en) | 2024-02-02 | 2025-08-07 | Editas Medicine, Inc. | MODIFIED GUIDE RNAs |
| WO2025213138A1 (en) | 2024-04-05 | 2025-10-09 | Editas Medicine, Inc. | Crispr/rna-guided nuclease related methods and compositions for treating primary open angle glaucoma |
| WO2026022677A1 (en) | 2024-07-22 | 2026-01-29 | Genevant Sciences Gmbh | Permanently charged cationic lipids |
| WO2026022656A2 (en) | 2024-07-22 | 2026-01-29 | Genevant Sciences Gmbh | Lipid particle formulations with permanently charged cationic lipids |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4618689A (en) | 1985-07-18 | 1986-10-21 | General Electric Company | Novel aminofunctional silicone compositions |
| JPH08166679A (ja) * | 1994-12-13 | 1996-06-25 | Fuji Xerox Co Ltd | 電子写真感光体およびのその製造方法 |
| DE10058620A1 (de) * | 2000-11-25 | 2002-05-29 | Degussa | Verfahren zur Herstellung von Aminoalkylsilanen |
| EP1519714B1 (en) | 2002-06-28 | 2010-10-20 | Protiva Biotherapeutics Inc. | Method and apparatus for producing liposomes |
| CA2532228C (en) * | 2003-07-16 | 2017-02-14 | Protiva Biotherapeutics, Inc. | Lipid encapsulated interfering rna |
| CA2605068A1 (en) * | 2005-04-15 | 2006-10-26 | The Board Of Regents Of The University Of Texas System | Delivery of sirna by neutral lipid compositions |
| US20070292688A1 (en) * | 2005-08-18 | 2007-12-20 | Eastman Kodak Company | Silylamine modified nanoparticulate carriers |
| ITMI20061766A1 (it) * | 2006-09-15 | 2008-03-16 | N P T S R L | Prepolimeri silano-terminati e relativi formulati adesivo-sigillanti |
| CA2721333C (en) | 2008-04-15 | 2020-12-01 | Protiva Biotherapeutics, Inc. | Novel lipid formulations for nucleic acid delivery |
| CA2740000C (en) | 2008-10-09 | 2017-12-12 | Tekmira Pharmaceuticals Corporation | Improved amino lipids and methods for the delivery of nucleic acids |
| EP2287212B1 (en) * | 2009-08-21 | 2014-03-26 | China Petroleum & Chemical Corporation | A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component |
| US9006417B2 (en) | 2010-06-30 | 2015-04-14 | Protiva Biotherapeutics, Inc. | Non-liposomal systems for nucleic acid delivery |
| US9028603B2 (en) * | 2011-06-09 | 2015-05-12 | The Research Foundation Of State University Of New York | Anti-fouling coating compositions and methods for preventing the fouling of surfaces |
| US10517822B2 (en) * | 2013-11-06 | 2019-12-31 | The University Of Chicago | Nanoscale carriers for the delivery or co-delivery of chemotherapeutics, nucleic acids and photosensitizers |
| WO2017019891A2 (en) * | 2015-07-29 | 2017-02-02 | Protiva Biotherapeutics, Inc. | Compositions and methods for silencing hepatitis b virus gene expression |
| CN106834355B (zh) * | 2015-12-07 | 2021-02-23 | 北京大学 | 一种阳离子复合脂质纳米盘及其制备方法和用途 |
| EP3269785A1 (de) * | 2016-07-13 | 2018-01-17 | Nitrochemie Aschau GmbH | Zusammensetzung für silikonkautschukmassen |
| AU2017379901B2 (en) * | 2016-12-21 | 2024-02-15 | Arbutus Biopharma Corporation | Methods for ameliorating infusion reactions |
| WO2019051257A2 (en) | 2017-09-11 | 2019-03-14 | Arbutus Biopharma Corporation | METHODS OF TREATING HEPATITIS B TYPE INFECTIONS |
| EP3959314A4 (en) * | 2019-04-26 | 2023-02-08 | Genevant Sciences Gmbh | LIPIDNANOPARTICLES |
| WO2022011156A1 (en) | 2020-07-10 | 2022-01-13 | Genevant Sciences Gmbh | Lipid nanoparticles for delivering therapeutics to lungs |
| AU2021403156A1 (en) * | 2020-12-18 | 2023-07-13 | Genevant Sciences Gmbh | Peg lipids and lipid nanoparticles |
-
2019
- 2019-11-08 AU AU2019376006A patent/AU2019376006A1/en active Pending
- 2019-11-08 JP JP2021525114A patent/JP2022501064A/ja active Pending
- 2019-11-08 MX MX2021005462A patent/MX2021005462A/es unknown
- 2019-11-08 CA CA3119051A patent/CA3119051A1/en active Pending
- 2019-11-08 CN CN201980088071.2A patent/CN113286622A/zh active Pending
- 2019-11-08 BR BR112021008953-5A patent/BR112021008953A2/pt unknown
- 2019-11-08 SG SG11202104682PA patent/SG11202104682PA/en unknown
- 2019-11-08 EA EA202191315A patent/EA202191315A1/ru unknown
- 2019-11-08 US US17/291,873 patent/US12350383B2/en active Active
- 2019-11-08 WO PCT/US2019/060556 patent/WO2020097520A1/en not_active Ceased
- 2019-11-08 KR KR1020217017640A patent/KR20210105888A/ko not_active Ceased
- 2019-11-08 EP EP19881045.9A patent/EP3877001A4/en active Pending
-
2021
- 2021-05-05 IL IL282957A patent/IL282957A/en unknown
- 2021-05-12 ZA ZA2021/03229A patent/ZA202103229B/en unknown
-
2024
- 2024-11-20 JP JP2024202026A patent/JP2025019119A/ja active Pending
-
2025
- 2025-05-27 US US19/219,802 patent/US20250281422A1/en active Pending
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