JP2023518944A5 - - Google Patents

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Publication number
JP2023518944A5
JP2023518944A5 JP2022556074A JP2022556074A JP2023518944A5 JP 2023518944 A5 JP2023518944 A5 JP 2023518944A5 JP 2022556074 A JP2022556074 A JP 2022556074A JP 2022556074 A JP2022556074 A JP 2022556074A JP 2023518944 A5 JP2023518944 A5 JP 2023518944A5
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JP
Japan
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lipid
alkyl
lipid particles
compound according
alkynyl
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JP2022556074A
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English (en)
Japanese (ja)
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JP7709981B2 (ja
JP2023518944A (ja
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Priority claimed from PCT/US2021/022201 external-priority patent/WO2021188389A2/en
Publication of JP2023518944A publication Critical patent/JP2023518944A/ja
Publication of JP2023518944A5 publication Critical patent/JP2023518944A5/ja
Application granted granted Critical
Publication of JP7709981B2 publication Critical patent/JP7709981B2/ja
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JP2022556074A 2020-03-17 2021-03-12 肝星細胞への治療薬の脂質ナノ粒子送達のためのカチオン性脂質 Active JP7709981B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062990939P 2020-03-17 2020-03-17
US62/990,939 2020-03-17
PCT/US2021/022201 WO2021188389A2 (en) 2020-03-17 2021-03-12 Cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells

Publications (3)

Publication Number Publication Date
JP2023518944A JP2023518944A (ja) 2023-05-09
JP2023518944A5 true JP2023518944A5 (enExample) 2024-03-22
JP7709981B2 JP7709981B2 (ja) 2025-07-17

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ID=77772142

Family Applications (1)

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JP2022556074A Active JP7709981B2 (ja) 2020-03-17 2021-03-12 肝星細胞への治療薬の脂質ナノ粒子送達のためのカチオン性脂質

Country Status (5)

Country Link
US (1) US20230150926A1 (enExample)
EP (1) EP4121018A4 (enExample)
JP (1) JP7709981B2 (enExample)
KR (1) KR20220154740A (enExample)
WO (1) WO2021188389A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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CN114105799B (zh) * 2022-01-25 2022-05-10 中山大学附属第七医院(深圳) 一种氨基脂质及其制备方法和应用
CN119677852A (zh) 2022-07-29 2025-03-21 麻省理工学院 抑制信号调节蛋白α(SIRPα)基因表达的组合物和方法
CN116999397B (zh) * 2023-07-23 2026-01-16 中国人民解放军空军军医大学 双膜融合靶向纳米递药系统的制备方法及其应用
US20250381150A1 (en) 2024-03-08 2025-12-18 Genzyme Corporation Lipid nanoparticles
WO2026003582A2 (en) 2024-06-27 2026-01-02 Axelyf ehf. Lipids and lipid nanoparticles
WO2026030375A2 (en) 2024-07-30 2026-02-05 Genzyme Corporation Lipid nanoparticles and methods of manufacture and use thereof
WO2026142951A1 (en) 2024-12-23 2026-07-02 Genzyme Corporation Pharmaceutical system

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