JP2023513698A5 - - Google Patents
Info
- Publication number
- JP2023513698A5 JP2023513698A5 JP2022548450A JP2022548450A JP2023513698A5 JP 2023513698 A5 JP2023513698 A5 JP 2023513698A5 JP 2022548450 A JP2022548450 A JP 2022548450A JP 2022548450 A JP2022548450 A JP 2022548450A JP 2023513698 A5 JP2023513698 A5 JP 2023513698A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound according
- hydrocarbyl
- alkenyl
- lipid particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062975116P | 2020-02-11 | 2020-02-11 | |
| US62/975,116 | 2020-02-11 | ||
| PCT/US2021/017676 WO2021163339A1 (en) | 2020-02-11 | 2021-02-11 | Cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023513698A JP2023513698A (ja) | 2023-04-03 |
| JP2023513698A5 true JP2023513698A5 (enExample) | 2024-02-21 |
| JP7843707B2 JP7843707B2 (ja) | 2026-04-10 |
Family
ID=77292598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022548450A Active JP7843707B2 (ja) | 2020-02-11 | 2021-02-11 | 肝星細胞への治療薬の脂質ナノ粒子送達のためのカチオン性脂質 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12673963B2 (enExample) |
| EP (1) | EP4103172A4 (enExample) |
| JP (1) | JP7843707B2 (enExample) |
| KR (1) | KR20220140531A (enExample) |
| CN (1) | CN115697321A (enExample) |
| AU (1) | AU2021218409A1 (enExample) |
| BR (1) | BR112022015803A2 (enExample) |
| CA (1) | CA3170547A1 (enExample) |
| IL (1) | IL295441B1 (enExample) |
| MX (1) | MX2022009861A (enExample) |
| WO (1) | WO2021163339A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3364949A4 (en) * | 2015-10-22 | 2019-07-31 | ModernaTX, Inc. | CANCER VACCINES |
| CN117045791B (zh) * | 2023-03-22 | 2025-10-03 | 中国药科大学 | 肝星状细胞neu1的靶向过表达剂在制备治疗肝纤维化的药物中的应用 |
| US20250381150A1 (en) | 2024-03-08 | 2025-12-18 | Genzyme Corporation | Lipid nanoparticles |
| JP2025168864A (ja) * | 2024-04-30 | 2025-11-12 | 信越化学工業株式会社 | 含窒素多官能オルガノキシシラン化合物の製造方法 |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| WO2026022656A2 (en) | 2024-07-22 | 2026-01-29 | Genevant Sciences Gmbh | Lipid particle formulations with permanently charged cationic lipids |
| WO2026022677A1 (en) | 2024-07-22 | 2026-01-29 | Genevant Sciences Gmbh | Permanently charged cationic lipids |
| WO2026030375A2 (en) | 2024-07-30 | 2026-02-05 | Genzyme Corporation | Lipid nanoparticles and methods of manufacture and use thereof |
| CN121622610A (zh) * | 2024-09-05 | 2026-03-10 | 苏州慧疗生物医药科技有限公司 | 向细胞内递送遗传物质的三组分脂质纳米颗粒及组合物 |
| WO2026142951A1 (en) | 2024-12-23 | 2026-07-02 | Genzyme Corporation | Pharmaceutical system |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB709345A (en) | 1950-08-28 | 1954-05-19 | California Research Corp | Unsymmetrical alkoxy (tri- and tetra-) siloxanes and processes for making the same |
| US2713064A (en) | 1953-12-07 | 1955-07-12 | Dow Corning | Bis-(trialkoxysilyl) benzenes and their use |
| US3029269A (en) * | 1956-08-21 | 1962-04-10 | California Research Corp | Silicon esters |
| DE1180359B (de) | 1962-05-15 | 1964-10-29 | Ruhrchemie Ag | Verfahren zur kontinuierlichen Herstellung von Orthokieselsaeureestern |
| NL134718C (enExample) | 1966-12-01 | |||
| US3810843A (en) * | 1971-05-28 | 1974-05-14 | Gen Electric | Silicone-silica compositions |
| CH632765A5 (de) * | 1977-09-09 | 1982-10-29 | Ciba Geigy Ag | Verfahren zur herstellung von siliciummodifizierten phthalsaeurederivaten. |
| CH641470A5 (de) | 1978-08-30 | 1984-02-29 | Ciba Geigy Ag | Imidgruppen enthaltende silane. |
| US4329486A (en) * | 1981-06-29 | 1982-05-11 | Olin Corporation | Process for preparing alkoxysilane cluster compounds by reacting a trialkoxysilanol with an amidated alkoxysilane cluster compound |
| JPH086040B2 (ja) * | 1990-10-26 | 1996-01-24 | 信越化学工業株式会社 | オルガノポリシロキサン組成物 |
| US5534592A (en) * | 1995-09-22 | 1996-07-09 | The Goodyear Tire & Rubber Company | High performance blend for tire treads |
| EP1519714B1 (en) | 2002-06-28 | 2010-10-20 | Protiva Biotherapeutics Inc. | Method and apparatus for producing liposomes |
| WO2005055248A2 (en) * | 2003-11-28 | 2005-06-16 | Merck Patent Gmbh | Organic semiconducting layer formulations comprising polyacenes and organic binder polymers |
| EP2099953B1 (en) * | 2006-09-29 | 2019-04-03 | Momentive Performance Materials Inc. | Storage stable composition of partial and/or complete condensate of hydrolyzable organofunctional silane |
| JP5316743B2 (ja) * | 2007-11-01 | 2013-10-16 | Ｊｓｒ株式会社 | ケイ素含有膜形成用組成物およびケイ素含有絶縁膜の形成方法 |
| JP5133092B2 (ja) | 2008-03-06 | 2013-01-30 | 花王株式会社 | 機能性物質放出剤 |
| EP2279254B1 (en) | 2008-04-15 | 2017-07-05 | Protiva Biotherapeutics Inc. | Novel lipid formulations for nucleic acid delivery |
| CN101724127A (zh) | 2008-10-16 | 2010-06-09 | 住友橡胶工业株式会社 | 聚合物、橡胶组合物及使用该橡胶组合物的轮胎 |
| EP2391343B1 (en) | 2009-01-29 | 2017-03-01 | Arbutus Biopharma Corporation | Improved lipid formulation for the delivery of nucleic acids |
| EP4481047A3 (en) | 2010-06-03 | 2025-04-16 | Alnylam Pharmaceuticals, Inc. | Biodegradable lipids for the delivery of active agents |
| US9006417B2 (en) | 2010-06-30 | 2015-04-14 | Protiva Biotherapeutics, Inc. | Non-liposomal systems for nucleic acid delivery |
| WO2012166949A1 (en) | 2011-05-31 | 2012-12-06 | Regents Of The University Of Minnesota | Silicate prodrugs and nanoparticles |
| CN102911401B (zh) | 2012-11-08 | 2014-04-23 | 广州市回天精细化工有限公司 | 一种羟基清除剂、其制备方法及含有它的硫化硅橡胶 |
| WO2015130584A2 (en) | 2014-02-25 | 2015-09-03 | Merck Sharp & Dohme Corp. | Lipid nanoparticle vaccine adjuvants and antigen delivery systems |
| CA2953341C (en) | 2014-06-25 | 2023-01-24 | Acuitas Therapeutics Inc. | Lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| CN106794141B (zh) | 2014-07-16 | 2021-05-28 | 诺华股份有限公司 | 将核酸包封在脂质纳米粒主体中的方法 |
| WO2018081480A1 (en) | 2016-10-26 | 2018-05-03 | Acuitas Therapeutics, Inc. | Lipid nanoparticle formulations |
| JP6614014B2 (ja) * | 2016-04-26 | 2019-12-04 | 信越化学工業株式会社 | 含窒素オルガノキシシラン化合物およびその製造方法 |
| WO2017205566A1 (en) | 2016-05-27 | 2017-11-30 | Preceres Inc. | Oxidized aminolipidoids and uses thereof |
| WO2019089828A1 (en) | 2017-10-31 | 2019-05-09 | Acuitas Therapeutics, Inc. | Lamellar lipid nanoparticles |
| DE102017221259A1 (de) * | 2017-11-28 | 2019-05-29 | Evonik Degussa Gmbh | Silanmischungen und Verfahren zu deren Herstellung |
| CN111565700B (zh) * | 2017-12-21 | 2023-06-09 | 3M创新有限公司 | 包括硅烷处理过的表面的无机牙科用填充剂 |
| CN108239103B (zh) | 2018-01-02 | 2020-09-01 | 深圳市广业电子科技有限公司 | 一种含有多肟基硅的硅氮化合物 |
| US11690804B2 (en) | 2018-07-02 | 2023-07-04 | Aptamir Therapeutics, Inc. | Targeted delivery of therapeutic agents to human adipocytes |
| AU2021403156A1 (en) * | 2020-12-18 | 2023-07-13 | Genevant Sciences Gmbh | Peg lipids and lipid nanoparticles |
-
2021
- 2021-02-11 CA CA3170547A patent/CA3170547A1/en active Pending
- 2021-02-11 BR BR112022015803A patent/BR112022015803A2/pt unknown
- 2021-02-11 KR KR1020227028723A patent/KR20220140531A/ko active Pending
- 2021-02-11 MX MX2022009861A patent/MX2022009861A/es unknown
- 2021-02-11 US US17/797,760 patent/US12673963B2/en active Active
- 2021-02-11 JP JP2022548450A patent/JP7843707B2/ja active Active
- 2021-02-11 AU AU2021218409A patent/AU2021218409A1/en active Pending
- 2021-02-11 WO PCT/US2021/017676 patent/WO2021163339A1/en not_active Ceased
- 2021-02-11 CN CN202180022603.XA patent/CN115697321A/zh active Pending
- 2021-02-11 IL IL295441A patent/IL295441B1/en unknown
- 2021-02-11 EP EP21753059.1A patent/EP4103172A4/en active Pending
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