JP2016519659A5 - - Google Patents
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- JP2016519659A5 JP2016519659A5 JP2016502225A JP2016502225A JP2016519659A5 JP 2016519659 A5 JP2016519659 A5 JP 2016519659A5 JP 2016502225 A JP2016502225 A JP 2016502225A JP 2016502225 A JP2016502225 A JP 2016502225A JP 2016519659 A5 JP2016519659 A5 JP 2016519659A5
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- Japan
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361794094P | 2013-03-15 | 2013-03-15 | |
| US61/794,094 | 2013-03-15 | ||
| PCT/US2014/026722 WO2014151953A1 (en) | 2013-03-15 | 2014-03-13 | Compounds and methods for inducing chondrogenesis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016519659A JP2016519659A (ja) | 2016-07-07 |
| JP2016519659A5 true JP2016519659A5 (https=) | 2017-04-13 |
| JP6579623B2 JP6579623B2 (ja) | 2019-09-25 |
Family
ID=51528123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502225A Active JP6579623B2 (ja) | 2013-03-15 | 2014-03-13 | 軟骨形成を誘導するための化合物及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US9452170B2 (https=) |
| EP (1) | EP2968330B1 (https=) |
| JP (1) | JP6579623B2 (https=) |
| KR (1) | KR102283996B1 (https=) |
| CN (3) | CN107007587A (https=) |
| AU (1) | AU2014236719B2 (https=) |
| CA (1) | CA2904160C (https=) |
| ES (1) | ES2900815T3 (https=) |
| HK (1) | HK1224172A1 (https=) |
| WO (1) | WO2014151953A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012129562A2 (en) * | 2011-03-24 | 2012-09-27 | The Scripps Research Institute | Compounds and methods for inducing chondrogenesis |
| ES2900815T3 (es) | 2013-03-15 | 2022-03-18 | Scripps Research Inst | Compuestos y métodos para inducir la condrogénesis |
| CN105294533A (zh) * | 2015-12-02 | 2016-02-03 | 宋彤云 | 一种治疗骨病的药物组合物 |
| CN109963579A (zh) * | 2016-11-14 | 2019-07-02 | 诺华股份有限公司 | 用于治疗软骨损伤和关节炎的方法和组合物 |
| AU2018257769A1 (en) * | 2017-04-24 | 2019-11-07 | The Scripps Research Institute | Methods for inducing chondrogenesis |
| UY37759A (es) * | 2017-06-09 | 2019-01-31 | Novartis Ag | Compuestos y composiciones para inducir condrogénesis |
| CN107056677A (zh) * | 2017-06-19 | 2017-08-18 | 常州大学 | 一种3‑烷基2,3‑二氢异吲哚啉酮衍生物的合成方法 |
| RU2020134972A (ru) * | 2018-03-29 | 2022-04-29 | Элекс Байотек, Инк. | Соединения для лечения сердечных аритмий и сердечной недостаточности |
| CN110937987B (zh) * | 2018-09-25 | 2022-09-06 | 深圳市灵兰生物医药科技有限公司 | 一种化合物的合成路线及在抗糖尿病药物制备领域的应用 |
| AU2019362747A1 (en) * | 2018-10-15 | 2021-06-03 | Gero Pte. Ltd. | PFKFB3 inhibitors and their uses |
| CN109730999B (zh) * | 2018-12-28 | 2021-12-24 | 中山大学 | 噻唑苯甲酰胺衍生在制备抗骨质疏松、抗骨关节炎药物中的应用 |
| WO2020142865A1 (zh) * | 2019-01-07 | 2020-07-16 | 江苏凯迪恩医药科技有限公司 | 一种苯甲酰胺类化合物、中间体、制备方法及应用 |
| EP3946301A4 (en) * | 2019-04-02 | 2023-08-09 | The University of Chicago | REMODILINS FOR RESPIRATORY TRACT REMODELING AND ORGAN FIBROSIS |
| JP7566405B2 (ja) * | 2020-08-05 | 2024-10-15 | エルジー・ケム・リミテッド | 変形性関節症の緩和又は治療するためのカスパーゼ阻害剤の使用 |
| CN114763346B (zh) * | 2021-01-15 | 2025-06-10 | 华东师范大学 | 一类用于诱导软骨形成的化合物及其应用 |
| CN114763347B (zh) * | 2021-01-15 | 2024-06-21 | 华东师范大学 | 一类用于诱导间充质干细胞向软骨分化的化合物及其应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1016623A (en) | 1911-09-06 | 1912-02-06 | Harry Haller Jr | Photographic-printing device. |
| CH489993A (de) | 1967-12-19 | 1970-05-15 | Ciba Geigy | Das Pflanzenwachstum regulierendes und phytocides Mittel |
| FR2059977A1 (https=) | 1969-08-14 | 1971-06-11 | Socibre | |
| KR0143565B1 (ko) | 1988-06-13 | 1998-07-15 | 사노 가즈오 | 피발산의 p-치환된 페닐 에스테르 유도체, 그의 제조 방법 및 이를 포함하는 조성물. |
| JPH0320253A (ja) * | 1988-06-13 | 1991-01-29 | Ono Pharmaceut Co Ltd | ピバル酸 ｐ―置換フェニルエステル誘導体、それらの製造方法およびそれらを有効成分として含有するエラスターゼ阻害剤 |
| JPH0959236A (ja) | 1995-08-23 | 1997-03-04 | Dai Ichi Seiyaku Co Ltd | ベンズアミド化合物 |
| US5729014A (en) | 1996-07-11 | 1998-03-17 | Varian Associates, Inc. | Method for injection of externally produced ions into a quadrupole ion trap |
| PL337020A1 (en) | 1997-05-22 | 2000-07-31 | Searle & Co | Substituted pyrazoles as kinase p38 inhibitors |
| US6514977B1 (en) | 1997-05-22 | 2003-02-04 | G.D. Searle & Company | Substituted pyrazoles as p38 kinase inhibitors |
| US6040321A (en) * | 1997-11-12 | 2000-03-21 | Bristol-Myers Squibb Company | Aminothiazole inhibitors of cyclin dependent kinases |
| US6632961B1 (en) | 1998-05-22 | 2003-10-14 | Abbott Laboratories | Antiangiogenic drug to treat cancer, arthritis and retinopathy |
| WO2002060859A2 (en) | 2000-12-20 | 2002-08-08 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| JP2005194191A (ja) * | 2001-12-28 | 2005-07-21 | Ajinomoto Co Inc | 抗肥満薬、脂肪肝治療薬 |
| US7087604B2 (en) * | 2002-03-08 | 2006-08-08 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| US7288538B2 (en) | 2003-02-20 | 2007-10-30 | Encysive Pharmaceuticals, Inc. | Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists |
| MXPA05012086A (es) | 2003-05-12 | 2006-02-22 | Pfizer Prod Inc | Inhibidores de benzamida del receptor p2x7. |
| EP1660072A2 (en) * | 2003-07-29 | 2006-05-31 | Universitätsklinikum Münster | Means and methods for treating a disease which is associated with an excess transport of hyaluronan across a lipid bilayer |
| US7163937B2 (en) | 2003-08-21 | 2007-01-16 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| US7863317B2 (en) * | 2003-08-21 | 2011-01-04 | Bristol-Myers Squibb Company | Lactams of alkylated acyclic diamine derivatives as modulators of chemokine receptor activity |
| US20070054916A1 (en) * | 2004-10-01 | 2007-03-08 | Amgen Inc. | Aryl nitrogen-containing bicyclic compounds and methods of use |
| US7776869B2 (en) | 2004-10-18 | 2010-08-17 | Amgen Inc. | Heteroaryl-substituted alkyne compounds and method of use |
| EP1820795A4 (en) * | 2004-12-07 | 2010-10-20 | Toyama Chemical Co Ltd | NEW ANTHRANILIC ACID DERIVATIVE OR SALT FROM IT |
| KR100787131B1 (ko) * | 2006-07-04 | 2007-12-21 | 한국생명공학연구원 | Ｈｉｆ―１ 활성을 저해하는 화합물, 이의 제조방법 및이를 유효성분으로 함유하는 약학적 조성물 |
| US8569378B2 (en) * | 2007-07-20 | 2013-10-29 | Toshiyuki Sakai | p27 protein inducer |
| CN101815514B (zh) * | 2007-10-05 | 2012-05-09 | 塞诺菲-安万特德国有限公司 | 磺酰基取代的2-磺酰基氨基苯甲酸n-苯基酰胺在治疗疼痛中的应用 |
| US8143269B2 (en) * | 2008-10-03 | 2012-03-27 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
| AU2010273570B2 (en) | 2009-07-14 | 2014-07-03 | Novartis Ag | Mesenchymal stem cell differentiation |
| SI2576548T1 (sl) * | 2010-05-26 | 2015-11-30 | Adverio Pharma Gmbh | Uporaba sGC stimulatorjev, sGC aktivatorjev, samih in v kombinacijah s PDE5 inhibitorji za zdravljenje sistemske skleroze |
| WO2012129562A2 (en) | 2011-03-24 | 2012-09-27 | The Scripps Research Institute | Compounds and methods for inducing chondrogenesis |
| ES2900815T3 (es) | 2013-03-15 | 2022-03-18 | Scripps Research Inst | Compuestos y métodos para inducir la condrogénesis |
| EP3143026B1 (en) | 2014-05-13 | 2024-07-10 | Novartis AG | Compounds and compositions for inducing chondrogenesis |
-
2014
- 2014-03-13 ES ES14770543T patent/ES2900815T3/es active Active
- 2014-03-13 US US14/210,198 patent/US9452170B2/en active Active
- 2014-03-13 CN CN201710295821.6A patent/CN107007587A/zh active Pending
- 2014-03-13 AU AU2014236719A patent/AU2014236719B2/en active Active
- 2014-03-13 US US14/774,673 patent/US10500210B2/en active Active
- 2014-03-13 CN CN201480028421.3A patent/CN105228626A/zh active Pending
- 2014-03-13 WO PCT/US2014/026722 patent/WO2014151953A1/en not_active Ceased
- 2014-03-13 KR KR1020157026707A patent/KR102283996B1/ko active Active
- 2014-03-13 JP JP2016502225A patent/JP6579623B2/ja active Active
- 2014-03-13 EP EP14770543.8A patent/EP2968330B1/en active Active
- 2014-03-13 CA CA2904160A patent/CA2904160C/en active Active
- 2014-03-13 HK HK16107019.4A patent/HK1224172A1/zh unknown
- 2014-03-13 CN CN202211717279.6A patent/CN116059196A/zh active Pending
-
2019
- 2019-11-15 US US16/685,555 patent/US11045476B2/en active Active
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