JP2016518827A - 細胞外核酸の安定化および単離 - Google Patents

細胞外核酸の安定化および単離 Download PDF

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Publication number
JP2016518827A
JP2016518827A JP2016503572A JP2016503572A JP2016518827A JP 2016518827 A JP2016518827 A JP 2016518827A JP 2016503572 A JP2016503572 A JP 2016503572A JP 2016503572 A JP2016503572 A JP 2016503572A JP 2016518827 A JP2016518827 A JP 2016518827A
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cell
sample
nucleic acid
butanamide
stabilization
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JP2016518827A5 (enExample
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ラルフ ヴュリヒ，
ラルフ ヴュリヒ，
トルステン フォス，
トルステン フォス，
ダニエル グレルツ，
ダニエル グレルツ，
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Qiagen GmbH
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Qiagen GmbH
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2016503572A 2013-03-18 2014-03-18 細胞外核酸の安定化および単離 Pending JP2016518827A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP13159834.4 2013-03-18
EP13159834 2013-03-18
EP13180086 2013-08-12
EP13180086.4 2013-08-12
PCT/EP2014/000726 WO2014146782A1 (en) 2013-03-18 2014-03-18 Stabilization and isolation of extracellular nucleic acids

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JP2016518827A true JP2016518827A (ja) 2016-06-30
JP2016518827A5 JP2016518827A5 (enExample) 2017-02-16

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JP2016503570A Active JP6407248B2 (ja) 2013-03-18 2014-03-18 細胞外核酸の安定化および単離

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US (2) US10144952B2 (enExample)
EP (2) EP2976425B1 (enExample)
JP (2) JP2016518827A (enExample)
CN (2) CN105164258B (enExample)
WO (2) WO2014146780A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022515969A (ja) * 2019-01-04 2022-02-24 キアゲン ゲーエムベーハー 尿安定化
JPWO2024070504A1 (enExample) * 2022-09-29 2024-04-04

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11021733B2 (en) 2011-09-26 2021-06-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
ES2574956T3 (es) 2011-09-26 2016-06-23 Preanalytix Gmbh Estabilización y aislamiento de ácidos nucleicos extracelulares
AU2012314514B2 (en) 2011-09-26 2018-03-15 Qiagen Gmbh Stabilisation and isolation of extracellular nucleic acids
US20150225712A1 (en) * 2012-08-21 2015-08-13 Qiagen Gmbh Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
CA2884915C (en) 2012-09-25 2022-05-17 Qiagen Gmbh Stabilisation of biological samples
CA2886389A1 (en) 2012-09-28 2014-04-03 Cepheid Methods for dna and rna extraction from fixed paraffin-embedded tissue samples
WO2014146780A1 (en) 2013-03-18 2014-09-25 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
EP3447141B1 (en) * 2013-03-18 2020-08-05 PreAnalytiX GmbH Stabilisation of biological samples
US20160374330A1 (en) 2014-03-18 2016-12-29 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
EP3325647B1 (en) * 2015-07-24 2020-02-19 Cepheid Compositions and methods for dna and rna extraction from tissue samples
CA3005694A1 (en) * 2015-11-20 2017-05-26 Qiagen Gmbh Method of preparing sterilized compositions for stabilization of extracellular nucleic acids
EP4043475B1 (en) * 2016-03-31 2023-09-20 Berkeley Lights, Inc. Nucleic acid stabilization reagent, kits, and methods of use thereof
CA3025569A1 (en) 2016-05-27 2017-11-30 Norgen Biotek Corp. Preservation of cell-free nucleic acids in biological samples
JP7109424B2 (ja) * 2016-08-17 2022-07-29 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 体液に基づくセルフリーＤＮＡ（ｃｆＤＮＡ）アッセイを通して臓器損傷状態を査定するための新規のイムノプローブに基づく方法
EP3358020B1 (en) 2017-01-05 2021-05-19 Biodesix, Inc. Diagnostic test system for specific, sensitive and reproducible detection of circulating nucleic acids in whole blood
US11591638B2 (en) * 2017-08-02 2023-02-28 Sarstedt Ag & Co. Kg Process and composition for the stabilization of cell-free nucleic acids and cells
CA3148731A1 (en) 2019-09-24 2021-04-01 Qiagen Gmbh Multimodal analysis of stabilized cell-containing bodily fluid samples
US20230203586A1 (en) * 2020-05-29 2023-06-29 The Rockefeller University Method and system for rna isolation from self-collected and small volume samples
JP7635480B2 (ja) * 2020-11-27 2025-02-26 大王製紙株式会社 Ｒｆｉｄタグ、採血管、及びアンテナ
EP4263383A4 (en) 2020-12-17 2024-10-23 Nephrosant, Inc. KITS FOR STABILIZATION OF URINE SAMPLES
CN118632688A (zh) 2021-11-19 2024-09-10 布朗卡布努斯有限公司 一种包含包装在药物递送载体中的治疗活性剂的组合物
EP4356731A1 (en) 2022-10-19 2024-04-24 Olga Alekseevna Gra Medium and device for collecting, storing and transporting biological samples, as well as their use for the stabilization of extracellular nucleic acids
EP4477751A1 (en) 2023-06-16 2024-12-18 QIAGEN GmbH Body fluid stabilization and processing

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000187033A (ja) * 1998-12-21 2000-07-04 Wako Pure Chem Ind Ltd 細胞染色液
JP2005501236A (ja) * 2001-08-23 2005-01-13 イムニベスト・コーポレイション 分析用の細胞および生物学的検体の安定化
JP2005524850A (ja) * 2002-05-07 2005-08-18 ベクトン・ディキンソン・アンド・カンパニー 採集装置
US20100255524A1 (en) * 2007-05-31 2010-10-07 Qiagen Gmbh Method for stabilising a biological sample
JP2014528719A (ja) * 2011-09-26 2014-10-30 プレアナリティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング 細胞外核酸の安定化および単離

Family Cites Families (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3389133A (en) 1966-08-10 1968-06-18 Schwarz Biores Inc Process for isolating and purifying soluble ribonucleic acid
US3903179A (en) 1973-10-15 1975-09-02 Gulf Research Development Co Method for preparing nitrocyclopropane from 3-chloro-1-nitropropane
JPS6083581A (ja) * 1983-10-13 1985-05-11 Hideaki Yamada シユ−ドモナス属細菌の培養法
US4938961A (en) 1989-04-28 1990-07-03 Geoffrey Collins Organ preservation solution containing pokyethylene gycol and method of performing cardioplegia
US5459073A (en) 1991-05-08 1995-10-17 Streck Laboratories, Inc. Method and composition for preserving antigens and process for utilizing cytological material produced by same
US5460797A (en) 1991-05-08 1995-10-24 Streck Laboratories, Inc. Method for fixing tissues and cells for analysis using oxazolidine compounds
GB9215002D0 (en) * 1992-07-15 1992-08-26 Univ Singapore Method of fixing biological tissue
DK0743950T3 (da) 1994-02-11 2002-03-25 Qiagen Gmbh Fremgangsmåde til adskillelse af dobbeltstrengede/enkeltstrengede nukleinsyre-strukturer
US5705628A (en) 1994-09-20 1998-01-06 Whitehead Institute For Biomedical Research DNA purification and isolation using magnetic particles
BR9510461A (pt) 1994-12-29 2004-01-06 Brookfield Eng Lab Instrumento rotacional e de medição rotacional com suporte axial e radial rìgido
US6673364B1 (en) 1995-06-07 2004-01-06 The University Of British Columbia Liposome having an exchangeable component
US20050158699A1 (en) 1995-06-07 2005-07-21 Kadkade Prakash G. Cryopreservation of plant cells
AU7514896A (en) * 1995-10-06 1997-04-28 E.I. Du Pont De Nemours And Company Nucleic acid fragments encoding stereospecific nitrile hydratase and amidase enzymes and recombinant microorganisms expressing those enzymes useful for the production of chiral amides and acides
ES2235225T3 (es) 1996-02-14 2005-07-01 Biomerieux B.V. Aislamiento de acidos nucleicos de ramalles simples.
US6156504A (en) 1996-03-15 2000-12-05 The Penn State Research Foundation Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
ES2347854T5 (es) 1996-03-26 2014-07-24 Michael S. Kopreski Método que permite el uso de RNA extracelular extraído de plasma o suero para detectar, monitorizar o evaluar un cáncer
US6077232A (en) 1996-12-27 2000-06-20 Sherwood Services Ag Anticoagulant composition
WO1998041651A1 (en) 1997-03-18 1998-09-24 Hsc Research & Development Limited Partnership Method for preparing chromatin
DE19726362A1 (de) 1997-06-21 1998-12-24 Schaeffler Waelzlager Ohg Vorrichtung zum Verändern der Steuerzeiten von Gaswechselventilen einer Brennkraftmaschine
US6723564B2 (en) * 1998-05-07 2004-04-20 Sequenom, Inc. IR MALDI mass spectrometry of nucleic acids using liquid matrices
US6534262B1 (en) 1998-05-14 2003-03-18 Whitehead Institute For Biomedical Research Solid phase technique for selectively isolating nucleic acids
DE19836559A1 (de) 1998-08-12 2000-03-23 Antigen Gmbh Gefäß zur Entnahme von Blut
US6407107B1 (en) * 1999-05-28 2002-06-18 The Board Of Trustees Of The Unversity Of Arkansas Derivatives of butyric acid and uses thereof
US6379930B1 (en) 1999-07-30 2002-04-30 Applied Gene Technologies, Inc. Stabilization of nucleic acid amplification cocktails
US6492103B1 (en) 2000-01-31 2002-12-10 Organ Recovery Systems, Inc. System for organ and tissue preservation and hypothermic blood substitution
DE10006662A1 (de) 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
CN1427729A (zh) 2000-03-23 2003-07-02 科利昂特有限公司 生物材料消毒方法
US7033810B2 (en) * 2000-04-18 2006-04-25 Amgen Inc. Sitosterolemia susceptibility gene (SSG): compositions and methods of use
DE10031236A1 (de) 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
US6602718B1 (en) 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
EP1482962A4 (en) * 2002-02-15 2009-12-23 Sloan Kettering Inst Cancer METHOD OF TREATING THIOREDOXIN-MEDIATED DISEASES (TRX)
US6977162B2 (en) 2002-03-01 2005-12-20 Ravgen, Inc. Rapid analysis of variations in a genome
WO2003086480A1 (en) 2002-04-10 2003-10-23 Clearant, Inc. Methods for sterilizing biological materials
US7442506B2 (en) 2002-05-08 2008-10-28 Ravgen, Inc. Methods for detection of genetic disorders
US20040054160A1 (en) 2002-09-16 2004-03-18 Santona Pal Nucleic-acid ink compositions for arraying onto a solid support
JP2006502415A (ja) 2002-10-10 2006-01-19 ベクトン・ディキンソン・アンド・カンパニー カスパーゼ阻害剤を有するサンプル収集システム
US20040167165A1 (en) * 2003-01-16 2004-08-26 Geetha Shankar Methods of treating conditions associated with an Edg-7 receptor
US7601491B2 (en) * 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
US7250270B2 (en) 2003-06-13 2007-07-31 Ambion, Inc. Methods and compositions for preparing tissue samples for RNA extraction
US20070208166A1 (en) * 2003-10-24 2007-09-06 Exelixis, Inc. Tao Kinase Modulators And Method Of Use
US7270799B2 (en) 2004-01-15 2007-09-18 Nst Neurosurvival Technologies Ltd. Perturbed membrane-binding compounds and methods of using the same
WO2005081867A2 (en) 2004-02-20 2005-09-09 The Regents Of The University Of C Alifornia Salivary mrna profiling, biomarkers, and related methods and kits of parts
EP1730305A2 (en) * 2004-02-28 2006-12-13 Chang-Ning J. Wang Nucleic acid complexes
US20080176209A1 (en) 2004-04-08 2008-07-24 Biomatrica, Inc. Integration of sample storage and sample management for life science
JP2008509226A (ja) 2004-05-24 2008-03-27 ジェンボールト コーポレイション 回収可能な形式での安定なタンパク質保管および安定な核酸保管
US20100190688A1 (en) 2004-07-12 2010-07-29 Bin Chao Tetrapeptide analogs
US7086126B2 (en) * 2004-07-30 2006-08-08 Speaks, Inc. Elastic band with snap-buckles for holding garment waistband
FR2883003B1 (fr) 2005-03-14 2008-04-11 Aldivia Sa Nouveaux antioxydants a base d'especes d'anacardiacees, plus particulierement de sclerocarya birrea, leurs procedes d'obtention et leurs applications
DE102005015005A1 (de) * 2005-04-01 2006-10-05 Qiagen Gmbh Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe
AU2011253662A1 (en) 2005-11-30 2011-12-22 Massachusetts Institute Of Technology Pathogen-detecting cell preservation systems
EP1804045B1 (de) 2005-12-30 2014-03-12 QIAGEN GmbH Ein Verfahren und ein Kit zur Behandlung einer biologischen Probe
CA2635978A1 (en) 2006-01-04 2007-07-12 Do-Coop Technologies Ltd. Solid-fluid composition
CA2637843C (en) 2006-01-20 2014-12-30 Reneuron, Inc. Method of improving cell proliferation of pancreatic progenitor cells in a pancreatic cell culture
US10925977B2 (en) * 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
GB0626021D0 (en) 2006-12-29 2007-02-07 Insense Ltd The stabilisation of proteins
US7828887B2 (en) 2007-04-23 2010-11-09 Hewlett-Packard Development Company, L.P. Dye-based ink formulations
JP5311760B2 (ja) 2007-05-25 2013-10-09 雪印メグミルク株式会社 美白剤
EP2027922A1 (de) 2007-08-02 2009-02-25 Qiagen GmbH Verfahren und Vorrichtung für das Fixieren/Stabilisieren einer Probe
US20100285468A1 (en) 2007-09-24 2010-11-11 Allelogic Biosciences Corporation Detection and/or quantification of nucleic acids
EP2259798B1 (en) * 2008-03-05 2013-12-11 Baxter International Inc. Surface-modified particles and methods for targeted drug delivery
US20100137575A1 (en) 2008-12-03 2010-06-03 Connolly D Michael Universal biological sample processing
US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
EP3290530B1 (en) 2009-02-18 2020-09-02 Streck Inc. Preservation of cell-free nucleic acids
US20100280233A1 (en) 2009-05-04 2010-11-04 Connolly Dennis M Method for sample preparation
US20150056604A1 (en) 2009-06-15 2015-02-26 Biovec Transfusion, Llc Compositions and methods for preserving platelet function
US20110027771A1 (en) 2009-07-31 2011-02-03 Artemis Health, Inc. Methods and compositions for cell stabilization
US8039613B2 (en) * 2009-08-28 2011-10-18 Promega Corporation Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
US8222397B2 (en) * 2009-08-28 2012-07-17 Promega Corporation Methods of optimal purification of nucleic acids and kit for use in performing such methods
NZ599583A (en) 2009-10-29 2013-09-27 Ascendis Pharma As Sterilization of biodegradable hydrogels
JP2013509883A (ja) 2009-11-06 2013-03-21 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ 臓器移植患者における移植片拒絶反応の非侵襲的診断方法
WO2011057184A1 (en) 2009-11-09 2011-05-12 Streck, Inc. Stabilization of rna in and extracting from intact cells within a blood sample
JP5773347B2 (ja) 2009-11-27 2015-09-02 国立大学法人 千葉大学 血液細胞の凍結保存剤
US8093427B2 (en) * 2010-06-09 2012-01-10 National Tsing Hua University Construction and screening of solution-phase derived library of fenbufen and ethacrynic acid
US20130095473A1 (en) 2010-06-14 2013-04-18 Qiagen Gmbh Method for determination of target cells or tissue for extraction of biomolecules from fixed biological samples
FR2964567B1 (fr) 2010-09-14 2013-03-15 Lvmh Rech Extrait d'orchidee
ES2668213T3 (es) 2011-05-03 2018-05-17 Agios Pharmaceuticals, Inc. Uso de activadores de piruvato quinasa para aumentar la vida útil de los glóbulos rojos de la sangre y tratar la anemia
ES2693672T3 (es) 2011-09-26 2018-12-13 Qiagen Gmbh Método rápido para aislar ácidos nucleicos extracelulares
EP2760999A1 (en) 2011-09-26 2014-08-06 Qiagen GmbH Methods for separating nucleic acids by size
AU2012314514B2 (en) * 2011-09-26 2018-03-15 Qiagen Gmbh Stabilisation and isolation of extracellular nucleic acids
US9994891B2 (en) 2011-10-11 2018-06-12 Qiagen Gmbh Sample processing method and sample processing cartridge
CA2855941A1 (en) 2011-11-14 2013-05-23 Advanced Cell Technology, Inc. Pharmaceutical preparations of human rpe cells and uses thereof
US9546358B2 (en) 2012-06-04 2017-01-17 New England Biolabs, Inc. Compositions and methods for reducing background DNA amplification
CA2884915C (en) 2012-09-25 2022-05-17 Qiagen Gmbh Stabilisation of biological samples
WO2014055936A1 (en) 2012-10-04 2014-04-10 Integenx Inc. Preservation of biological materials in non-aqueous fluid media
GB201303666D0 (en) 2013-03-01 2013-04-17 Goldsborough Andrew S Sample fixation and stabilisation
WO2014146780A1 (en) 2013-03-18 2014-09-25 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
EP3447141B1 (en) 2013-03-18 2020-08-05 PreAnalytiX GmbH Stabilisation of biological samples
US20160374330A1 (en) 2014-03-18 2016-12-29 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
CN106796219B (zh) 2014-08-07 2022-05-27 通用医疗公司 全血样品的稳定化

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000187033A (ja) * 1998-12-21 2000-07-04 Wako Pure Chem Ind Ltd 細胞染色液
JP2005501236A (ja) * 2001-08-23 2005-01-13 イムニベスト・コーポレイション 分析用の細胞および生物学的検体の安定化
JP2005524850A (ja) * 2002-05-07 2005-08-18 ベクトン・ディキンソン・アンド・カンパニー 採集装置
US20100255524A1 (en) * 2007-05-31 2010-10-07 Qiagen Gmbh Method for stabilising a biological sample
JP2014528719A (ja) * 2011-09-26 2014-10-30 プレアナリティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング 細胞外核酸の安定化および単離

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NAWAZ, M. ET AL.: "Degradation of Aliphatic Amide Mixture by Immobilized and Nonimmobilized Cells of Pseudomonas sp.", ENVIRON. SCI. TECHNOL., vol. 28, JPN6017043424, 1994, pages 1106 - 1109, ISSN: 0003833010 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022515969A (ja) * 2019-01-04 2022-02-24 キアゲン ゲーエムベーハー 尿安定化
JP7548904B2 (ja) 2019-01-04 2024-09-10 キアゲン ゲーエムベーハー 尿安定化
JPWO2024070504A1 (enExample) * 2022-09-29 2024-04-04
WO2024070504A1 (ja) * 2022-09-29 2024-04-04 積水メディカル株式会社 血液保存用組成物及び血液採取容器
JP7586593B2 (ja) 2022-09-29 2024-11-19 積水メディカル株式会社 血液保存用組成物及び血液採取容器

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US20160281132A1 (en) 2016-09-29
JP6407248B2 (ja) 2018-10-17
US20160281133A1 (en) 2016-09-29
EP2976425A1 (en) 2016-01-27
WO2014146780A1 (en) 2014-09-25
WO2014146782A1 (en) 2014-09-25
CN105164258B (zh) 2021-05-18
JP2016520293A (ja) 2016-07-14
EP2976425B1 (en) 2019-11-06
CN105121643A (zh) 2015-12-02
US10144952B2 (en) 2018-12-04
CN105164258A (zh) 2015-12-16
EP2976426A1 (en) 2016-01-27

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