JP2016518334A5 - - Google Patents
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- Publication number
- JP2016518334A5 JP2016518334A5 JP2016502514A JP2016502514A JP2016518334A5 JP 2016518334 A5 JP2016518334 A5 JP 2016518334A5 JP 2016502514 A JP2016502514 A JP 2016502514A JP 2016502514 A JP2016502514 A JP 2016502514A JP 2016518334 A5 JP2016518334 A5 JP 2016518334A5
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- JP
- Japan
- Prior art keywords
- alkyl
- haloalkyl
- cycloalkyl
- independently
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361787422P | 2013-03-15 | 2013-03-15 | |
| US61/787,422 | 2013-03-15 | ||
| PCT/US2014/027679 WO2014152738A1 (en) | 2013-03-15 | 2014-03-14 | Lxr modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016518334A JP2016518334A (ja) | 2016-06-23 |
| JP2016518334A5 true JP2016518334A5 (enExample) | 2017-04-20 |
| JP6456909B2 JP6456909B2 (ja) | 2019-01-23 |
Family
ID=51581300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502514A Expired - Fee Related JP6456909B2 (ja) | 2013-03-15 | 2014-03-14 | Ｌｘｒ調節因子 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9751869B2 (enExample) |
| EP (1) | EP2967073B9 (enExample) |
| JP (1) | JP6456909B2 (enExample) |
| CN (1) | CN105188380B (enExample) |
| ES (1) | ES2694001T3 (enExample) |
| WO (1) | WO2014152738A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014144037A1 (en) | 2013-03-15 | 2014-09-18 | Bristol-Myers Squibb Company | Lxr modulators |
| ITUA20164199A1 (it) * | 2016-06-08 | 2017-12-08 | Univ Degli Studi Del Piemonte Orientale Amedeo Avogadro | Modulatori di soce compisizioni e relativi usi |
| WO2018091389A1 (en) | 2016-11-17 | 2018-05-24 | Syngenta Participations Ag | Pesticidally active heterocyclic derivatives with sulphur containing substituents |
| WO2021028645A1 (en) | 2019-08-09 | 2021-02-18 | Kalvista Pharmaceuticals Limited | Plasma kallikrein inhibitors |
| CN113457708B (zh) * | 2021-06-30 | 2023-10-20 | 常州大学 | CoN@C多孔材料及其制备方法以及在芳香族腈类化合物的合成中的应用 |
| EP4536655A2 (en) * | 2022-06-10 | 2025-04-16 | Sionna Therapeutics Inc. | Compounds, compositions, and methods of using thereof |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0252290B1 (en) | 1986-06-10 | 1992-06-03 | CHIESI FARMACEUTICI S.p.A. | Pharmaceutical compositions containing levodopa methyl ester, preparation and therapeutic applications thereof |
| US5434178A (en) * | 1993-11-30 | 1995-07-18 | G.D. Searle & Co. | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation |
| US5908852A (en) * | 1994-11-14 | 1999-06-01 | G. D. Searle & Co. | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation |
| WO2000078972A2 (en) | 1999-06-18 | 2000-12-28 | Cv Therapeutics, Inc. | Regulation with binding cassette transporter protein abc1 |
| WO2001082917A2 (en) | 2000-05-03 | 2001-11-08 | Tularik Inc. | Treatment of hypertriglyceridemia and other conditions using lxr modulators |
| US6924311B2 (en) | 2001-10-17 | 2005-08-02 | X-Ceptor Therapeutics, Inc. | Methods for affecting various diseases utilizing LXR compounds |
| US7482366B2 (en) | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
| EP1465869B1 (en) | 2001-12-21 | 2013-05-15 | Exelixis Patent Company LLC | Modulators of lxr |
| US7247735B2 (en) * | 2002-07-26 | 2007-07-24 | Infineon Technologies Ag | Octupolar molecules used as organic semiconductors |
| AU2003293376A1 (en) | 2002-12-10 | 2004-06-30 | Imclone Systems Incorporated | Anti-angiogenic compounds and their use in cancer treatment |
| MY142651A (en) | 2003-03-18 | 2010-12-15 | Merck Sharp & Dohme | Biaryl substituted triazoles as sodium channel blockers |
| CA2522476A1 (en) | 2003-04-18 | 2004-11-04 | Merck & Co., Inc. | Biaryl substituted thiazoles, oxazoles and imidazoles as sodium channel blockers |
| JP2008533200A (ja) * | 2005-03-21 | 2008-08-21 | メルク エンド カムパニー インコーポレーテッド | 置換アリールおよびヘテロアリール誘導体、かかる化合物を含有する組成物および使用法 |
| MX2008000141A (es) | 2005-06-27 | 2008-04-07 | Exelixis Inc | Moduladores de lxr basados en imidazol. |
| EP2121621B1 (en) * | 2006-12-08 | 2014-05-07 | Exelixis Patent Company LLC | Lxr and fxr modulators |
| DK2435410T3 (da) | 2009-05-28 | 2017-04-10 | Exelixis Patent Co Llc | LXR-modulatorer |
| HUE040231T2 (hu) * | 2012-03-02 | 2019-02-28 | Ralexar Therapeutics Inc | Máj X receptor (LXR) modulátorok bõrbetegségek, rendellenességek és állapotok kezelésére |
| WO2014144037A1 (en) | 2013-03-15 | 2014-09-18 | Bristol-Myers Squibb Company | Lxr modulators |
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2014
- 2014-03-14 ES ES14770510T patent/ES2694001T3/es active Active
- 2014-03-14 US US14/774,839 patent/US9751869B2/en not_active Expired - Fee Related
- 2014-03-14 WO PCT/US2014/027679 patent/WO2014152738A1/en not_active Ceased
- 2014-03-14 EP EP14770510.7A patent/EP2967073B9/en active Active
- 2014-03-14 CN CN201480027521.4A patent/CN105188380B/zh not_active Expired - Fee Related
- 2014-03-14 JP JP2016502514A patent/JP6456909B2/ja not_active Expired - Fee Related