|
EP2935240A1
(en)
|
2012-12-21 |
2015-10-28 |
Epizyme, Inc. |
Prmt5 inhibitors and uses thereof
|
|
WO2014100716A1
(en)
|
2012-12-21 |
2014-06-26 |
Epizyme, Inc. |
Prmt5 inhibitors and uses thereof
|
|
JP2016505002A
(ja)
|
2012-12-21 |
2016-02-18 |
エピザイム，インコーポレイティド |
ジヒドロイソキノリンまたはテトラヒドロイソキノリンを含有するｐｒｍｔ５阻害剤およびその使用
|
|
CA2894157A1
(en)
|
2012-12-21 |
2014-06-26 |
Epizyme, Inc. |
Prmt5 inhibitors and uses thereof
|
|
KR102173874B1
(ko)
|
2012-12-21 |
2020-11-05 |
에피자임, 인코포레이티드 |
테트라하이드로- 및 디하이드로-이소퀴놀린 prmt5 억제제 및 이의 용도
|
|
US9120757B2
(en)
|
2013-03-14 |
2015-09-01 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
|
WO2014144659A1
(en)
|
2013-03-14 |
2014-09-18 |
Epizyme, Inc. |
Pyrazole derivatives as prmt1 inhibitors and uses thereof
|
|
ES2837034T3
(es)
|
2013-03-14 |
2021-06-29 |
Epizyme Inc |
Inhibidores de arginina metiltransferasa y usos de los mismos
|
|
CA2903264A1
(en)
|
2013-03-14 |
2014-11-06 |
Epizyme, Inc. |
Pyrazole derivatives as arginine methyltransferase inhibitors and uses thereof
|
|
US9133189B2
(en)
|
2013-03-14 |
2015-09-15 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
|
US9045455B2
(en)
|
2013-03-14 |
2015-06-02 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
|
US9738651B2
(en)
|
2013-03-15 |
2017-08-22 |
Epizyme, Inc. |
CARM1 inhibitors and uses thereof
|
|
US9718816B2
(en)
|
2013-03-15 |
2017-08-01 |
Epizyme, Inc. |
1-phenoxy-3-(alkylamino)-propan-2-ol derivatives as CARM1 inhibitors and uses thereof
|
|
JO3805B1
(ar)
|
2013-10-10 |
2021-01-31 |
Araxes Pharma Llc |
مثبطات كراس جي12سي
|
|
EP3177288A4
(en)
|
2014-08-04 |
2018-04-04 |
Epizyme, Inc. |
Prmt5 inhibitors and uses thereof
|
|
WO2017070089A1
(en)
|
2015-10-19 |
2017-04-27 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
ES2928856T3
(es)
|
2015-11-19 |
2022-11-23 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
WO2017106634A1
(en)
|
2015-12-17 |
2017-06-22 |
Incyte Corporation |
N-phenyl-pyridine-2-carboxamide derivatives and their use as pd-1/pd-l1 protein/protein interaction modulators
|
|
TWI850624B
(zh)
|
2015-12-22 |
2024-08-01 |
美商英塞特公司 |
作為免疫調節劑之雜環化合物
|
|
ES2906460T3
(es)
|
2016-05-06 |
2022-04-18 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
TW201808902A
(zh)
|
2016-05-26 |
2018-03-16 |
美商英塞特公司 |
作為免疫調節劑之雜環化合物
|
|
PT3472167T
(pt)
|
2016-06-20 |
2022-11-11 |
Incyte Corp |
Compostos heterocíclicos como imunomoduladores
|
|
US20180016260A1
(en)
|
2016-07-14 |
2018-01-18 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
MA46045A
(fr)
|
2016-08-29 |
2021-04-28 |
Incyte Corp |
Composés hétérocycliques utilisés comme immunomodulateurs
|
|
US11160823B2
(en)
|
2016-11-07 |
2021-11-02 |
University Of Massachusetts |
Therapeutic targets for facioscapulohumeral muscular dystrophy
|
|
RS63710B1
(sr)
|
2016-12-22 |
2022-11-30 |
Incyte Corp |
Derivati tetrahidro imidazo[4,5-c] piridina kao induktori internalizacije pd-l1
|
|
EP3558973B1
(en)
|
2016-12-22 |
2021-09-15 |
Incyte Corporation |
Pyridine derivatives as immunomodulators
|
|
JP7101678B2
(ja)
|
2016-12-22 |
2022-07-15 |
インサイト・コーポレイション |
免疫調節剤としての複素環式化合物
|
|
TW201835049A
(zh)
|
2016-12-22 |
2018-10-01 |
美商英塞特公司 |
作為免疫調節劑之雜環化合物
|
|
US20180179201A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
EP3573964A1
(en)
|
2017-01-26 |
2019-12-04 |
Araxes Pharma LLC |
Benzothiophene and benzothiazole compounds and methods of use thereof
|
|
JP7327802B2
(ja)
|
2017-01-26 |
2023-08-16 |
アラクセス ファーマ エルエルシー |
縮合ヘテロ－ヘテロ二環式化合物およびその使用方法
|
|
WO2018140512A1
(en)
|
2017-01-26 |
2018-08-02 |
Araxes Pharma Llc |
Fused bicyclic benzoheteroaromatic compounds and methods of use thereof
|
|
WO2018140514A1
(en)
|
2017-01-26 |
2018-08-02 |
Araxes Pharma Llc |
1-(6-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)azetidin-1-yl)prop-2-en-1-one derivatives and similar compounds as kras g12c inhibitors for the treatment of cancer
|
|
US11279689B2
(en)
|
2017-01-26 |
2022-03-22 |
Araxes Pharma Llc |
1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1 yl)prop-2-en-1-one derivatives and similar compounds as KRAS G12C modulators for treating cancer
|
|
LT3448859T
(lt)
|
2017-03-20 |
2019-10-25 |
Forma Therapeutics Inc |
Pirolpirolo kompozicijos, kaip piruvato kinazės (pkr) aktyvatoriai
|
|
CN110831933A
(zh)
|
2017-05-25 |
2020-02-21 |
亚瑞克西斯制药公司 |
喹唑啉衍生物作为突变kras、hras或nras的调节剂
|
|
CA3063440A1
(en)
|
2017-05-25 |
2018-11-29 |
Araxes Pharma Llc |
Covalent inhibitors of kras
|
|
RS66699B1
(sr)
|
2018-03-30 |
2025-05-30 |
Incyte Corp |
Heterociklična jedinjenja kao imunomodulatori
|
|
TW202425987A
(zh)
|
2018-05-11 |
2024-07-01 |
美商英塞特公司 |
作為免疫調節劑之雜環化合物
|
|
CN112584833A
(zh)
*
|
2018-08-01 |
2021-03-30 |
亚瑞克西斯制药公司 |
杂环螺化合物及其用于治疗癌症的使用方法
|
|
ES2989438T3
(es)
|
2018-09-19 |
2024-11-26 |
Novo Nordisk Healthcare Ag |
Activación de la piruvato cinasa R
|
|
US10675274B2
(en)
|
2018-09-19 |
2020-06-09 |
Forma Therapeutics, Inc. |
Activating pyruvate kinase R
|
|
JP2022539556A
(ja)
|
2019-06-28 |
2022-09-12 |
エイエルエス・セラピー・デベロップメント・インスティテュート |
ジペプチドリピートタンパク質の阻害
|
|
TW202115059A
(zh)
|
2019-08-09 |
2021-04-16 |
美商英塞特公司 |
Ｐｄ—１／ｐｄ—ｌ１抑制劑之鹽
|
|
HUE072832T2
(hu)
|
2019-09-19 |
2025-12-28 |
Novo Nordisk Healthcare Ag |
Piruvát kináz R-t (PKR) aktiváló készítmények
|
|
JP7559059B2
(ja)
|
2019-09-30 |
2024-10-01 |
インサイト・コーポレイション |
免疫調節剤としてのピリド［３，２－ｄ］ピリミジン化合物
|
|
PH12022551136A1
(en)
|
2019-11-11 |
2023-10-09 |
Incyte Corp |
Salts and crystalline forms of a pd-1/pd-l1 inhibitor
|
|
JP2023518396A
(ja)
*
|
2020-03-18 |
2023-05-01 |
デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド |
Ｃａｒｍ１の阻害によるがん治療法
|
|
TW202233616A
(zh)
|
2020-11-06 |
2022-09-01 |
美商英塞特公司 |
用於製備ｐｄ－１／ｐｄ－ｌ１抑制劑以及其鹽及結晶形式之方法
|
|
US11780836B2
(en)
|
2020-11-06 |
2023-10-10 |
Incyte Corporation |
Process of preparing a PD-1/PD-L1 inhibitor
|
|
TW202233615A
(zh)
|
2020-11-06 |
2022-09-01 |
美商英塞特公司 |
Ｐｄ—１／ｐｄ—ｌ１抑制劑之結晶形式
|
|
US12128035B2
(en)
|
2021-03-19 |
2024-10-29 |
Novo Nordisk Health Care Ag |
Activating pyruvate kinase R
|