|
US9745291B2
(en)
|
2012-12-21 |
2017-08-29 |
Epizyme, Inc. |
PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof
|
|
WO2014100716A1
(en)
|
2012-12-21 |
2014-06-26 |
Epizyme, Inc. |
Prmt5 inhibitors and uses thereof
|
|
US9908887B2
(en)
|
2012-12-21 |
2018-03-06 |
Epizyme, Inc. |
PRMT5 inhibitors and uses thereof
|
|
JP2016505597A
(ja)
|
2012-12-21 |
2016-02-25 |
エピザイム,インコーポレイティド |
Prmt5阻害剤およびその使用
|
|
US8993555B2
(en)
|
2012-12-21 |
2015-03-31 |
Epizyme, Inc. |
PRMT5 inhibitors and uses thereof
|
|
US9120757B2
(en)
|
2013-03-14 |
2015-09-01 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
|
US9023883B2
(en)
|
2013-03-14 |
2015-05-05 |
Epizyme, Inc. |
PRMT1 inhibitors and uses thereof
|
|
EP2970136A1
(en)
|
2013-03-14 |
2016-01-20 |
Epizyme, Inc. |
Arginine methyl transferase inhibtors and uses thereof
|
|
WO2014153226A1
(en)
|
2013-03-14 |
2014-09-25 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
|
EP2970181B1
(en)
|
2013-03-14 |
2017-06-07 |
Epizyme, Inc. |
Arginine methyltransferase inhibitors and uses thereof
|
|
JP2016514164A
(ja)
|
2013-03-14 |
2016-05-19 |
エピザイム,インコーポレイティド |
アルギニンメチルトランスフェラーゼ阻害剤としてのピラゾール誘導体およびその使用
|
|
EP2970266B1
(en)
|
2013-03-15 |
2018-01-31 |
Epizyme, Inc. |
1-phenoxy-3-(alkylamino)-propan-2-ol derivatives as carm1 inhibitors and uses thereof
|
|
US9738651B2
(en)
|
2013-03-15 |
2017-08-22 |
Epizyme, Inc. |
CARM1 inhibitors and uses thereof
|
|
JO3805B1
(ar)
|
2013-10-10 |
2021-01-31 |
Araxes Pharma Llc |
مثبطات كراس جي12سي
|
|
US10653693B2
(en)
|
2014-08-04 |
2020-05-19 |
Epizyme, Inc. |
PRMT5 inhibitors and uses thereof
|
|
ES2928164T3
(es)
|
2015-10-19 |
2022-11-15 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
MD3377488T2
(ro)
|
2015-11-19 |
2023-02-28 |
Incyte Corp |
Compuși heterociclici ca imunomodulatori
|
|
MA44075A
(fr)
|
2015-12-17 |
2021-05-19 |
Incyte Corp |
Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1
|
|
MY199705A
(en)
|
2015-12-22 |
2023-11-20 |
Incyte Corp |
Heterocyclic compounds as immunomodulators
|
|
WO2017192961A1
(en)
|
2016-05-06 |
2017-11-09 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
WO2017205464A1
(en)
|
2016-05-26 |
2017-11-30 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
KR102685249B1
(ko)
|
2016-06-20 |
2024-07-17 |
인사이트 코포레이션 |
면역조절제로서의 복소환식 화합물
|
|
MA45669A
(fr)
|
2016-07-14 |
2019-05-22 |
Incyte Corp |
Composés hétérocycliques utilisés comme immunomodulateurs
|
|
WO2018044783A1
(en)
|
2016-08-29 |
2018-03-08 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
JP7231226B2
(ja)
|
2016-11-07 |
2023-03-01 |
ユニバーシティ オブ マサチューセッツ |
顔面肩甲上腕型筋ジストロフィーのための治療標的
|
|
WO2018119224A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Tetrahydro imidazo[4,5-c]pyridine derivatives as pd-l1 internalization inducers
|
|
CA3047991A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Bicyclic heteroaromatic compounds as immunomodulators
|
|
PE20191532A1
(es)
|
2016-12-22 |
2019-10-23 |
Incyte Corp |
Compuestos heterociclicos como inmunomoduladores
|
|
EP3558973B1
(en)
|
2016-12-22 |
2021-09-15 |
Incyte Corporation |
Pyridine derivatives as immunomodulators
|
|
EP3558989B1
(en)
|
2016-12-22 |
2021-04-14 |
Incyte Corporation |
Triazolo[1,5-a]pyridine derivatives as immunomodulators
|
|
WO2018140513A1
(en)
|
2017-01-26 |
2018-08-02 |
Araxes Pharma Llc |
1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1yl)prop-2-en-1-one derivatives and similar compounds as kras g12c modulators for treating cancer
|
|
US11358959B2
(en)
|
2017-01-26 |
2022-06-14 |
Araxes Pharma Llc |
Benzothiophene and benzothiazole compounds and methods of use thereof
|
|
CN110382482A
(zh)
|
2017-01-26 |
2019-10-25 |
亚瑞克西斯制药公司 |
稠合的杂-杂二环化合物及其使用方法
|
|
EP3573954A1
(en)
|
2017-01-26 |
2019-12-04 |
Araxes Pharma LLC |
Fused bicyclic benzoheteroaromatic compounds and methods of use thereof
|
|
US11136308B2
(en)
|
2017-01-26 |
2021-10-05 |
Araxes Pharma Llc |
Substituted quinazoline and quinazolinone compounds and methods of use thereof
|
|
EP3680241A1
(en)
|
2017-03-20 |
2020-07-15 |
Forma Therapeutics, Inc. |
Pyrrolopyrrole compositions as pyruvate kinase (pkr) activators
|
|
CN110869358A
(zh)
|
2017-05-25 |
2020-03-06 |
亚瑞克西斯制药公司 |
Kras的共价抑制剂
|
|
CN110831933A
(zh)
|
2017-05-25 |
2020-02-21 |
亚瑞克西斯制药公司 |
喹唑啉衍生物作为突变kras、hras或nras的调节剂
|
|
RS64055B1
(sr)
|
2018-03-30 |
2023-04-28 |
Incyte Corp |
Heterociklična jedinjenja kao imunomodulatori
|
|
MD3790877T2
(ro)
|
2018-05-11 |
2023-08-31 |
Incyte Corp |
Derivați de tetrahidro-imidazo[4,5-c]piridină în calitate de imunomodulatori PD-L1
|
|
BR112021001709A2
(pt)
*
|
2018-08-01 |
2021-05-04 |
Araxes Pharma Llc |
compostos espiro heterocíclicos e métodos de uso dos mesmos para o tratamento de câncer
|
|
WO2020061255A1
(en)
|
2018-09-19 |
2020-03-26 |
Forma Therapeutics, Inc. |
Activating pyruvate kinase r
|
|
US10675274B2
(en)
|
2018-09-19 |
2020-06-09 |
Forma Therapeutics, Inc. |
Activating pyruvate kinase R
|
|
AU2020303943B2
(en)
|
2019-06-28 |
2026-01-29 |
Als Therapy Development Institute |
Inhibition of dipeptide repeat proteins
|
|
JP7665593B2
(ja)
|
2019-08-09 |
2025-04-21 |
インサイト・コーポレイション |
Pd-1/pd-l1阻害剤の塩
|
|
HUE072832T2
(hu)
|
2019-09-19 |
2025-12-28 |
Novo Nordisk Healthcare Ag |
Piruvát kináz R-t (PKR) aktiváló készítmények
|
|
AR120109A1
(es)
|
2019-09-30 |
2022-02-02 |
Incyte Corp |
Compuestos de pirido[3,2-d]pirimidina como inmunomoduladores
|
|
PE20230407A1
(es)
|
2019-11-11 |
2023-03-07 |
Incyte Corp |
Sales y formas cristalinas de un inhibidor de pd-1/pd-l1
|
|
JP2023518396A
(ja)
*
|
2020-03-18 |
2023-05-01 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
Carm1の阻害によるがん治療法
|
|
TW202233616A
(zh)
|
2020-11-06 |
2022-09-01 |
美商英塞特公司 |
用於製備pd-1/pd-l1抑制劑以及其鹽及結晶形式之方法
|
|
WO2022099075A1
(en)
|
2020-11-06 |
2022-05-12 |
Incyte Corporation |
Crystalline form of a pd-1/pd-l1 inhibitor
|
|
WO2022099018A1
(en)
|
2020-11-06 |
2022-05-12 |
Incyte Corporation |
Process of preparing a pd-1/pd-l1 inhibitor
|
|
US12128035B2
(en)
|
2021-03-19 |
2024-10-29 |
Novo Nordisk Health Care Ag |
Activating pyruvate kinase R
|