JP2016517390A - ヘパリノイド、即時作用性麻酔薬、及び緩衝液を含む安定組成物 - Google Patents

ヘパリノイド、即時作用性麻酔薬、及び緩衝液を含む安定組成物 Download PDF

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Publication number
JP2016517390A
JP2016517390A JP2015555403A JP2015555403A JP2016517390A JP 2016517390 A JP2016517390 A JP 2016517390A JP 2015555403 A JP2015555403 A JP 2015555403A JP 2015555403 A JP2015555403 A JP 2015555403A JP 2016517390 A JP2016517390 A JP 2016517390A
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JP
Japan
Prior art keywords
buffer
composition
heparinoid
heparin
lidocaine
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Pending
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JP2015555403A
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English (en)
Japanese (ja)
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JP2016517390A5 (enExample
Inventor
パーソンズ、シー．ローエル
Original Assignee
ウリゲン ファーマシューティカルズ、インコーポレイテッド
ウリゲン ファーマシューティカルズ、インコーポレイテッド
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Application filed by ウリゲン ファーマシューティカルズ、インコーポレイテッド, ウリゲン ファーマシューティカルズ、インコーポレイテッド filed Critical ウリゲン ファーマシューティカルズ、インコーポレイテッド
Publication of JP2016517390A publication Critical patent/JP2016517390A/ja
Publication of JP2016517390A5 publication Critical patent/JP2016517390A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Anesthesiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015555403A 2013-01-28 2014-01-28 ヘパリノイド、即時作用性麻酔薬、及び緩衝液を含む安定組成物 Pending JP2016517390A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361757592P 2013-01-28 2013-01-28
US61/757,592 2013-01-28
PCT/US2014/013352 WO2014171986A1 (en) 2013-01-28 2014-01-28 Stable compositions comprising heparinoid, acute-acting anesthetic, and buffer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018152223A Division JP2019006783A (ja) 2013-01-28 2018-08-13 ヘパリノイド、即時作用性麻酔薬、及び緩衝液を含む安定組成物

Publications (2)

Publication Number Publication Date
JP2016517390A true JP2016517390A (ja) 2016-06-16
JP2016517390A5 JP2016517390A5 (enExample) 2017-03-02

Family

ID=51731742

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015555403A Pending JP2016517390A (ja) 2013-01-28 2014-01-28 ヘパリノイド、即時作用性麻酔薬、及び緩衝液を含む安定組成物
JP2018152223A Pending JP2019006783A (ja) 2013-01-28 2018-08-13 ヘパリノイド、即時作用性麻酔薬、及び緩衝液を含む安定組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018152223A Pending JP2019006783A (ja) 2013-01-28 2018-08-13 ヘパリノイド、即時作用性麻酔薬、及び緩衝液を含む安定組成物

Country Status (13)

Country Link
US (1) US20150359816A1 (enExample)
EP (1) EP2948154A4 (enExample)
JP (2) JP2016517390A (enExample)
KR (1) KR20160008496A (enExample)
CN (1) CN105263503A (enExample)
AU (2) AU2014254472A1 (enExample)
BR (1) BR112015018047A8 (enExample)
CA (1) CA2899636C (enExample)
IL (1) IL240194B (enExample)
MX (1) MX2015009696A (enExample)
SG (1) SG11201505853RA (enExample)
WO (1) WO2014171986A1 (enExample)
ZA (1) ZA201505814B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022520895A (ja) * 2019-04-26 2022-04-01 ティーシーエム バイオテック インターナショナル コーポレーション 再発性尿路感染症の予防のための医薬組成物
JP2022550658A (ja) * 2019-07-18 2022-12-05 シー ローウェル パーソンズ 膀胱痛症状の緩和を促進するための、膀胱内ヘパリンおよびアルカリ化リドカインによる治療前の、膀胱壁のアルカリ化

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10117847B2 (en) * 2015-12-04 2018-11-06 Ventis Pharma Extended duration local anesthetic formulation
CA3090767A1 (en) 2017-02-27 2018-08-30 Urigen N.A. Treatment of lower urinary tract epithelium with glucagon like peptide 2
CN111787915A (zh) 2017-04-12 2020-10-16 尤里根制药股份有限公司 注射器中包含局部麻醉剂、缓冲剂和糖胺聚糖的稳定性提高的制品
EP3400951B1 (de) * 2017-05-12 2019-12-11 Farco-Pharma GmbH Blaseninstillationszusammensetzung enthaltend chondoitinsulfat (4,5 mg/ml), hyaluronsäure (16 mg/ml) und phosphatpuffer (ph 6,1 bis 7,9) mit erhöhter lagerstabiliät zur behandlung von cystitis
EP3415163B1 (de) * 2017-06-13 2023-02-22 Farco-Pharma GmbH Zusammensetzung mit lokalanästhetischer wirkung und deren verwendung
TWI887239B (zh) * 2019-05-17 2025-06-21 日商半導體能源研究所股份有限公司 發光元件、發光裝置、電子機器及照明裝置
CN115814099B (zh) * 2022-12-19 2024-04-26 成都蓉生药业有限责任公司 一种人凝血因子ix的干热处理稳定剂及其制剂与制备方法
MX2023012862A (es) * 2023-10-27 2023-11-09 Mar Mariana Guerrero Composicion topica de agentes esclerosantes en portadores acuosos.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008537535A (ja) * 2005-01-14 2008-09-18 ウーリゲン、インコーポレイテッド 下部尿路障害を治療するためのキット及び改良された組成物
JP2011529762A (ja) * 2008-08-04 2011-12-15 アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエ 麻酔剤を含有するヒアルロン酸系ゲル
WO2012094515A1 (en) * 2011-01-06 2012-07-12 Parsons C Lowell Method for manufacturing composition comprising local anesthetic, heparinoid, and buffer
US20120321693A1 (en) * 2009-08-13 2012-12-20 Benjamin David Sullivan Prg4 treatment for interstitial cystitis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5603695A (en) * 1995-06-07 1997-02-18 Erickson; Kim Device for alkalizing local anesthetic injection medication
SI1708722T1 (sl) * 2004-01-28 2014-10-30 The Regents Of The University Of California Nova intersticijska terapija za takojšnje simptome sprostitve in kronična terapija pri intersticijskem cistitisu
WO2007073397A1 (en) * 2005-12-19 2007-06-28 Urigen, Inc. Kits and improved compositions for treating lower urinary tract discorders
US9486747B2 (en) * 2014-08-12 2016-11-08 The Curators Of The University Of Missouri Nanocomposite membranes with advanced antifouling properties under visible light irradiation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008537535A (ja) * 2005-01-14 2008-09-18 ウーリゲン、インコーポレイテッド 下部尿路障害を治療するためのキット及び改良された組成物
JP2011529762A (ja) * 2008-08-04 2011-12-15 アラーガン・アンデュストリー・ソシエテ・パール・アクシオン・サンプリフィエ 麻酔剤を含有するヒアルロン酸系ゲル
US20120321693A1 (en) * 2009-08-13 2012-12-20 Benjamin David Sullivan Prg4 treatment for interstitial cystitis
WO2012094515A1 (en) * 2011-01-06 2012-07-12 Parsons C Lowell Method for manufacturing composition comprising local anesthetic, heparinoid, and buffer

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022520895A (ja) * 2019-04-26 2022-04-01 ティーシーエム バイオテック インターナショナル コーポレーション 再発性尿路感染症の予防のための医薬組成物
JP7083968B2 (ja) 2019-04-26 2022-06-13 ティーシーエム バイオテック インターナショナル コーポレーション 再発性尿路感染症の予防のための医薬組成物
JP2022550658A (ja) * 2019-07-18 2022-12-05 シー ローウェル パーソンズ 膀胱痛症状の緩和を促進するための、膀胱内ヘパリンおよびアルカリ化リドカインによる治療前の、膀胱壁のアルカリ化

Also Published As

Publication number Publication date
BR112015018047A2 (pt) 2017-07-18
CN105263503A (zh) 2016-01-20
IL240194A0 (en) 2015-09-24
CA2899636C (en) 2021-05-25
SG11201505853RA (en) 2015-08-28
AU2014254472A1 (en) 2015-08-20
US20150359816A1 (en) 2015-12-17
WO2014171986A1 (en) 2014-10-23
CA2899636A1 (en) 2014-10-23
AU2018247284A1 (en) 2018-11-01
JP2019006783A (ja) 2019-01-17
EP2948154A4 (en) 2016-09-14
EP2948154A1 (en) 2015-12-02
ZA201505814B (en) 2016-11-30
IL240194B (en) 2021-12-01
KR20160008496A (ko) 2016-01-22
MX2015009696A (es) 2016-03-31
BR112015018047A8 (pt) 2019-11-05

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