IL240194B - Preparations containing the farinoid, an anesthetic agent with an acute effect and a buffer, and processes for their preparation - Google Patents

Preparations containing the farinoid, an anesthetic agent with an acute effect and a buffer, and processes for their preparation

Info

Publication number
IL240194B
IL240194B IL240194A IL24019415A IL240194B IL 240194 B IL240194 B IL 240194B IL 240194 A IL240194 A IL 240194A IL 24019415 A IL24019415 A IL 24019415A IL 240194 B IL240194 B IL 240194B
Authority
IL
Israel
Prior art keywords
heparinoid
acute
buffer
stable compositions
acting anesthetic
Prior art date
Application number
IL240194A
Other languages
English (en)
Hebrew (he)
Other versions
IL240194A0 (en
Inventor
Lowell Parsons C
Original Assignee
Vaneltix Pharma Inc
Lowell Parsons C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaneltix Pharma Inc, Lowell Parsons C filed Critical Vaneltix Pharma Inc
Publication of IL240194A0 publication Critical patent/IL240194A0/en
Publication of IL240194B publication Critical patent/IL240194B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Anesthesiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL240194A 2013-01-28 2015-07-28 Preparations containing the farinoid, an anesthetic agent with an acute effect and a buffer, and processes for their preparation IL240194B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361757592P 2013-01-28 2013-01-28
PCT/US2014/013352 WO2014171986A1 (en) 2013-01-28 2014-01-28 Stable compositions comprising heparinoid, acute-acting anesthetic, and buffer

Publications (2)

Publication Number Publication Date
IL240194A0 IL240194A0 (en) 2015-09-24
IL240194B true IL240194B (en) 2021-12-01

Family

ID=51731742

Family Applications (1)

Application Number Title Priority Date Filing Date
IL240194A IL240194B (en) 2013-01-28 2015-07-28 Preparations containing the farinoid, an anesthetic agent with an acute effect and a buffer, and processes for their preparation

Country Status (13)

Country Link
US (1) US20150359816A1 (enExample)
EP (1) EP2948154A4 (enExample)
JP (2) JP2016517390A (enExample)
KR (1) KR20160008496A (enExample)
CN (1) CN105263503A (enExample)
AU (2) AU2014254472A1 (enExample)
BR (1) BR112015018047A8 (enExample)
CA (1) CA2899636C (enExample)
IL (1) IL240194B (enExample)
MX (1) MX2015009696A (enExample)
SG (1) SG11201505853RA (enExample)
WO (1) WO2014171986A1 (enExample)
ZA (1) ZA201505814B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10117847B2 (en) * 2015-12-04 2018-11-06 Ventis Pharma Extended duration local anesthetic formulation
CA3090767A1 (en) 2017-02-27 2018-08-30 Urigen N.A. Treatment of lower urinary tract epithelium with glucagon like peptide 2
CN111787915A (zh) 2017-04-12 2020-10-16 尤里根制药股份有限公司 注射器中包含局部麻醉剂、缓冲剂和糖胺聚糖的稳定性提高的制品
EP3400951B1 (de) * 2017-05-12 2019-12-11 Farco-Pharma GmbH Blaseninstillationszusammensetzung enthaltend chondoitinsulfat (4,5 mg/ml), hyaluronsäure (16 mg/ml) und phosphatpuffer (ph 6,1 bis 7,9) mit erhöhter lagerstabiliät zur behandlung von cystitis
EP3415163B1 (de) * 2017-06-13 2023-02-22 Farco-Pharma GmbH Zusammensetzung mit lokalanästhetischer wirkung und deren verwendung
ES2968164T3 (es) * 2019-04-26 2024-05-08 Tcm Biotech Int Corp Composición farmacéutica para la prevención de infección urinaria recurrente
TWI887239B (zh) * 2019-05-17 2025-06-21 日商半導體能源研究所股份有限公司 發光元件、發光裝置、電子機器及照明裝置
AU2020315353A1 (en) 2019-07-18 2022-03-10 C. Lowell Parsons Alkalization of urinary bladder wall prior to treatment with intravesical heparin and alkalinized lidocaine to enhance relief of bladder pain symptoms
CN115814099B (zh) * 2022-12-19 2024-04-26 成都蓉生药业有限责任公司 一种人凝血因子ix的干热处理稳定剂及其制剂与制备方法
MX2023012862A (es) * 2023-10-27 2023-11-09 Mar Mariana Guerrero Composicion topica de agentes esclerosantes en portadores acuosos.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005072751A1 (en) * 2004-01-28 2005-08-11 The Regents Of The University Of California Novel interstitial therapy for immediate symptom relief and chronic therapy in interstitial cystitis
WO2007073397A1 (en) * 2005-12-19 2007-06-28 Urigen, Inc. Kits and improved compositions for treating lower urinary tract discorders
WO2012094515A1 (en) * 2011-01-06 2012-07-12 Parsons C Lowell Method for manufacturing composition comprising local anesthetic, heparinoid, and buffer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5603695A (en) * 1995-06-07 1997-02-18 Erickson; Kim Device for alkalizing local anesthetic injection medication
EP2839830B1 (en) * 2005-01-14 2019-05-15 Urigen, Inc. Kits and compositions for treating lower urinary tract disorders
US8357795B2 (en) * 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
ES2634505T3 (es) * 2009-08-13 2017-09-28 Lubris Llc Tratamiento de PRG4 para la cistitis intersticial
US9486747B2 (en) * 2014-08-12 2016-11-08 The Curators Of The University Of Missouri Nanocomposite membranes with advanced antifouling properties under visible light irradiation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005072751A1 (en) * 2004-01-28 2005-08-11 The Regents Of The University Of California Novel interstitial therapy for immediate symptom relief and chronic therapy in interstitial cystitis
WO2007073397A1 (en) * 2005-12-19 2007-06-28 Urigen, Inc. Kits and improved compositions for treating lower urinary tract discorders
WO2012094515A1 (en) * 2011-01-06 2012-07-12 Parsons C Lowell Method for manufacturing composition comprising local anesthetic, heparinoid, and buffer

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
: C. LOWELL PARSONS ET AL, " ALKALINIZED LIDOCAINE AND HEPARIN PROVIDE IMMEDIATE RELIEF OF PAIN AND URGENCY IN PATIENTS WITH INTERSTITIAL CYSTITIS", 1 January 2012 (2012-01-01) *
PARSONS ET AL, " SUCCESSFUL DOWNREGULATION OF BLADDER SENSORY NERVES WITH COMBINATION OF HEPARIN AND ALKALINIZED LIDOCAINE IN PATIENTS WITH INTERSTITIAL CYSTITIS", 1 January 2005 (2005-01-01) *
WELK ET AL, " DYSPAREUNIA RESPONSE IN PATIENTS WITH INTERSTITIAL CYSTITIS TREATED WITH INTRAVESICAL LIDOCAINE, BICARBONATE, AND HEPARIN", 30 January 2008 (2008-01-30) *
YI-SONG LV ET AL, " INTRAVESICAL HYALURONIC ACID AND ALKALINIZED LIDOCAINE FOR THE TREATMENT OF SEVERE PAINFUL BLADDER SYNDROME/INTERSTITIAL CYSTITIS" ,, 11 May 2012 (2012-05-11) *

Also Published As

Publication number Publication date
BR112015018047A2 (pt) 2017-07-18
CN105263503A (zh) 2016-01-20
IL240194A0 (en) 2015-09-24
CA2899636C (en) 2021-05-25
SG11201505853RA (en) 2015-08-28
AU2014254472A1 (en) 2015-08-20
US20150359816A1 (en) 2015-12-17
WO2014171986A1 (en) 2014-10-23
CA2899636A1 (en) 2014-10-23
AU2018247284A1 (en) 2018-11-01
JP2019006783A (ja) 2019-01-17
EP2948154A4 (en) 2016-09-14
JP2016517390A (ja) 2016-06-16
EP2948154A1 (en) 2015-12-02
ZA201505814B (en) 2016-11-30
KR20160008496A (ko) 2016-01-22
MX2015009696A (es) 2016-03-31
BR112015018047A8 (pt) 2019-11-05

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