JP2016515214A5 - - Google Patents
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- JP2016515214A5 JP2016515214A5 JP2016502075A JP2016502075A JP2016515214A5 JP 2016515214 A5 JP2016515214 A5 JP 2016515214A5 JP 2016502075 A JP2016502075 A JP 2016502075A JP 2016502075 A JP2016502075 A JP 2016502075A JP 2016515214 A5 JP2016515214 A5 JP 2016515214A5
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- Prior art keywords
- droplet
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- downstream
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361798516P | 2013-03-15 | 2013-03-15 | |
| US61/798,516 | 2013-03-15 | ||
| PCT/US2014/026185 WO2014151658A1 (en) | 2013-03-15 | 2014-03-13 | High-speed on demand microfluidic droplet generation and manipulation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016515214A JP2016515214A (ja) | 2016-05-26 |
| JP2016515214A5 true JP2016515214A5 (enExample) | 2017-04-13 |
| JP6461905B2 JP6461905B2 (ja) | 2019-01-30 |
Family
ID=51581005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502075A Expired - Fee Related JP6461905B2 (ja) | 2013-03-15 | 2014-03-13 | 高速オンデマンド型マイクロ流体液滴生成及び操作 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10071359B2 (enExample) |
| EP (1) | EP2972405B1 (enExample) |
| JP (1) | JP6461905B2 (enExample) |
| KR (1) | KR102168053B1 (enExample) |
| CN (1) | CN105452873B (enExample) |
| AU (1) | AU2014233699B2 (enExample) |
| CA (1) | CA2909687A1 (enExample) |
| WO (1) | WO2014151658A1 (enExample) |
Families Citing this family (58)
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| US9364831B2 (en) | 2009-08-08 | 2016-06-14 | The Regents Of The University Of California | Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting |
| US9176504B2 (en) | 2011-02-11 | 2015-11-03 | The Regents Of The University Of California | High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation |
| GB2539836B (en) | 2012-08-13 | 2017-03-29 | Univ California | Methods for detecting target nucleic acids in sample lysate droplets |
| US10071359B2 (en) | 2013-03-15 | 2018-09-11 | The Regents Of The University Of California | High-speed on demand microfluidic droplet generation and manipulation |
| EP3160654A4 (en) | 2014-06-27 | 2017-11-15 | The Regents of The University of California | Pcr-activated sorting (pas) |
| CN105441309B (zh) * | 2014-08-27 | 2018-04-27 | 中国科学院苏州纳米技术与纳米仿生研究所 | 循环式单细胞捕获转移芯片 |
| CN105441308B (zh) * | 2014-08-27 | 2018-03-20 | 中国科学院苏州纳米技术与纳米仿生研究所 | 循环式单细胞捕获芯片 |
| WO2016064755A2 (en) * | 2014-10-20 | 2016-04-28 | The Regents Of The University Of Califronia | Rapid modulation of droplet composition with membrane microvalves |
| US10434507B2 (en) | 2014-10-22 | 2019-10-08 | The Regents Of The University Of California | High definition microdroplet printer |
| US11111519B2 (en) | 2015-02-04 | 2021-09-07 | The Regents Of The University Of California | Sequencing of nucleic acids via barcoding in discrete entities |
| WO2016133783A1 (en) * | 2015-02-17 | 2016-08-25 | Zalous, Inc. | Microdroplet digital pcr system |
| CN106290492A (zh) * | 2015-05-11 | 2017-01-04 | 宁波大学 | 驱动用构件易拆解并可循环再用的霍乱诊断用装置 |
| US9855555B2 (en) | 2015-05-20 | 2018-01-02 | University Of Maryland | Generation and trapping of aqueous droplets in a microfluidic chip with an air continuous phase |
| CN106290856A (zh) * | 2015-05-26 | 2017-01-04 | 宁波大学 | 四通道并且双驱动耦合运作的艾滋病诊断用微流控装置 |
| CN106290931A (zh) * | 2015-05-26 | 2017-01-04 | 宁波大学 | 以廉价疏水材质作基片的亚型猪流感检测用多通道装置 |
| CN106290857A (zh) * | 2015-05-26 | 2017-01-04 | 宁波大学 | 多通道且双驱动耦合运作的霍乱诊断用微流控芯片装置 |
| CN106290932A (zh) * | 2015-05-26 | 2017-01-04 | 宁波大学 | 包含疏水基片的双驱动耦合的艾滋病诊断用多通道装置 |
| CN106290933A (zh) * | 2015-05-26 | 2017-01-04 | 宁波大学 | 双机制驱动耦合运作的霍乱诊断用微流控芯片装置 |
| CN106290930A (zh) * | 2015-05-26 | 2017-01-04 | 宁波大学 | 含疏水基片的双驱动耦合的亚型猪流感多通道检测装置 |
| CN105136763B (zh) * | 2015-09-10 | 2017-10-13 | 大连海事大学 | 基于气液界面单细胞捕获及叶绿素荧光表征的单微藻细胞活性动态监测新方法与装置 |
| CN106556708A (zh) * | 2015-09-24 | 2017-04-05 | 宁波大学 | 两种驱动方式耦合运作的含疏水基片的微流控芯片装置 |
| EP3269444A1 (en) * | 2016-07-14 | 2018-01-17 | Base4 Innovation Ltd | Method of identifying droplets in a stack and an associated sequencer |
| US11142791B2 (en) | 2016-08-10 | 2021-10-12 | The Regents Of The University Of California | Combined multiple-displacement amplification and PCR in an emulsion microdroplet |
| US11376595B2 (en) | 2016-11-30 | 2022-07-05 | Pilot Gene Technologies (Hangzhou) Co., Ltd. | Droplet digital PCR chip |
| WO2018119301A1 (en) | 2016-12-21 | 2018-06-28 | The Regents Of The University Of California | Single cell genomic sequencing using hydrogel based droplets |
| EP3645167A4 (en) | 2017-06-28 | 2021-02-24 | Bio-rad Laboratories, Inc. | DROPLET DETECTION SYSTEM AND METHOD |
| CN107694475B (zh) * | 2017-09-25 | 2021-02-19 | 南京航空航天大学 | 一种微纳物质的环状聚集物成形装置 |
| US20200376740A1 (en) | 2017-10-03 | 2020-12-03 | Cornell University | Systems and methods for micropatterning objects |
| US10501739B2 (en) | 2017-10-18 | 2019-12-10 | Mission Bio, Inc. | Method, systems and apparatus for single cell analysis |
| CN107904155B (zh) * | 2017-10-19 | 2021-06-22 | 广州市第一人民医院 | 一种用于液体分散的微流控芯片及其应用、使用方法 |
| US11045805B2 (en) | 2017-11-01 | 2021-06-29 | Bio-Rad Laboratories, Inc. | Microfluidic system and method for arranging objects |
| JP7030361B2 (ja) * | 2017-11-06 | 2022-03-07 | 北京新▲い▼生物科技有限公司 | 微小液滴生成装置 |
| WO2020002197A1 (en) | 2018-06-27 | 2020-01-02 | Institut Curie | Method of inducing or preventing the merging of droplets |
| EP3586964A1 (en) | 2018-06-27 | 2020-01-01 | Inorevia | Method of manipulating droplets in a channel |
| US11173464B2 (en) | 2018-07-30 | 2021-11-16 | Hrl Laboratories, Llc | Methods for dissolving droplet particle assembly with co-solvent, and particle assemblies obtained therefrom |
| US11167287B2 (en) | 2018-07-30 | 2021-11-09 | Hrl Laboratories, Llc | Dissolving droplet microfluidic particle assembly devices and methods, and particle assemblies obtained therefrom |
| US11845061B1 (en) | 2018-07-30 | 2023-12-19 | Hrl Laboratories, Llc | Complex structures obtained from dissolving-droplet nanoparticle assembly |
| EP3613498A1 (en) * | 2018-08-24 | 2020-02-26 | Université de Liège | Microfluidic module for co-encapsulation in droplets |
| CN109456890A (zh) * | 2018-11-23 | 2019-03-12 | 大连理工大学 | 一种分层带状共培养4种肝细胞的微流控芯片及其应用 |
| CN111215159B (zh) * | 2018-11-26 | 2024-10-25 | 上海欣戈赛生物科技有限公司 | 微流控芯片及基于该芯片融合样本的方法 |
| CA3138806A1 (en) | 2019-05-22 | 2020-11-26 | Dalia Dhingra | Method and apparatus for simultaneous targeted sequencing of dna, rna and protein |
| WO2021003255A1 (en) | 2019-07-01 | 2021-01-07 | Mission Bio | Method and apparatus to normalize quantitative readouts in single-cell experiments |
| US20220250077A1 (en) * | 2019-07-24 | 2022-08-11 | Hewlett-Packard Development Company, L.P. | Digital microfluidics device with droplet processing components |
| US12194660B2 (en) | 2019-08-30 | 2025-01-14 | Drexel University | 3D capillary self-assembly of long aspect ratio particles |
| US12372465B2 (en) | 2019-11-15 | 2025-07-29 | Scintimetrics, Inc. | Compositions and methods based on diffusion of fluorophores |
| CN115485068A (zh) * | 2020-01-24 | 2022-12-16 | 康比纳蒂股份有限公司 | 用于微流体装置制造的方法和系统 |
| US11376812B2 (en) | 2020-02-11 | 2022-07-05 | Helicoid Industries Inc. | Shock and impact resistant structures |
| US12275227B2 (en) | 2020-02-11 | 2025-04-15 | Helicoid Industries, Inc. | Composite materials and structures |
| CN115279482B (zh) * | 2020-03-13 | 2024-12-13 | 国立研究开发法人科学技术振兴机构 | 微液滴、气泡生成装置 |
| CN112871227B (zh) * | 2021-01-07 | 2022-10-11 | 中国科学院青岛生物能源与过程研究所 | 基于光热效应进行微量液滴操控的微流控芯片及方法 |
| US11852297B2 (en) | 2021-06-01 | 2023-12-26 | Helicoid Industries Inc. | Containers and methods for protecting pressure vessels |
| US11346499B1 (en) | 2021-06-01 | 2022-05-31 | Helicoid Industries Inc. | Containers and methods for protecting pressure vessels |
| IT202100014972A1 (it) | 2021-06-09 | 2021-09-09 | Iodo S R L | Sistema microfluidico a liquidi espansi per la produzione di drug carrier |
| CN113652333B (zh) * | 2021-08-03 | 2023-03-21 | 中国科学院上海微系统与信息技术研究所 | 一种优化流体分布的微柱式多相位移通道 |
| JP2025526269A (ja) | 2022-06-27 | 2025-08-13 | ヘリコイド インダストリーズ インコーポレイテッド | 空気力学的構造物の前縁保護のための高耐衝撃性強化繊維 |
| US11802870B1 (en) | 2022-12-13 | 2023-10-31 | Panazee | Kinetic immunoassay systems and methods |
| US12030053B1 (en) | 2023-05-05 | 2024-07-09 | Panazee Inc. | Multi-step kinetic immunoassay systems and methods |
| CN119633919A (zh) * | 2024-12-31 | 2025-03-18 | 利德健康科技(广州)有限公司 | 液滴生成结构、微流控流道、微流控芯片及液滴生成方法 |
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| JP2832117B2 (ja) | 1991-11-29 | 1998-12-02 | キヤノン株式会社 | サンプル測定デバイス及びサンプル測定システム |
| US6143496A (en) | 1997-04-17 | 2000-11-07 | Cytonix Corporation | Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly |
| US7214298B2 (en) | 1997-09-23 | 2007-05-08 | California Institute Of Technology | Microfabricated cell sorter |
| US6899137B2 (en) | 1999-06-28 | 2005-05-31 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US6524456B1 (en) | 1999-08-12 | 2003-02-25 | Ut-Battelle, Llc | Microfluidic devices for the controlled manipulation of small volumes |
| US20060128006A1 (en) | 1999-11-10 | 2006-06-15 | Gerhardt Antimony L | Hydrodynamic capture and release mechanisms for particle manipulation |
| CA2390375A1 (en) | 1999-11-10 | 2001-05-17 | Massachusetts Institute Of Technology | Cell analysis and sorting apparatus for manipulation of cells |
| JP2001158099A (ja) | 1999-12-02 | 2001-06-12 | Fuji Xerox Co Ltd | インクジェット記録ヘッド及びインクジェット記録装置 |
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| GB0105831D0 (en) | 2001-03-09 | 2001-04-25 | Toumaz Technology Ltd | Method for dna sequencing utilising enzyme linked field effect transistors |
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| US7901939B2 (en) | 2002-05-09 | 2011-03-08 | University Of Chicago | Method for performing crystallization and reactions in pressure-driven fluid plugs |
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| WO2004091763A2 (en) * | 2003-04-10 | 2004-10-28 | President And Fellows Of Harvard College | Formation and control of fluidic species |
| GB0315438D0 (en) * | 2003-07-02 | 2003-08-06 | Univ Manchester | Analysis of mixed cell populations |
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| JP4661942B2 (ja) | 2008-05-13 | 2011-03-30 | ソニー株式会社 | マイクロチップとその流路構造 |
| KR100955845B1 (ko) * | 2008-05-15 | 2010-05-04 | 재단법인서울대학교산학협력재단 | 액적 병합장치 및 이를 이용한 액적 병합 방법 |
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| KR100967414B1 (ko) * | 2008-11-27 | 2010-07-01 | 한국과학기술원 | 유체 방울 혼합용 미세 유체 제어 장치 및 이를 이용하여 유체 방울을 혼합하는 방법 |
| JP2010169551A (ja) * | 2009-01-23 | 2010-08-05 | Foundation For The Promotion Of Industrial Science | 駆動部を有する微小液滴の配列装置 |
| WO2010092845A1 (ja) | 2009-02-13 | 2010-08-19 | コニカミノルタホールディングス株式会社 | マイクロ流路構造体及びマイクロポンプ |
| KR101125060B1 (ko) * | 2009-07-22 | 2012-03-21 | 한국과학기술원 | 입자를 포획하는 미세유체 소자 및 이를 이용한 입자 포획 방법 |
| US9364831B2 (en) | 2009-08-08 | 2016-06-14 | The Regents Of The University Of California | Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting |
| US9625454B2 (en) | 2009-09-04 | 2017-04-18 | The Research Foundation For The State University Of New York | Rapid and continuous analyte processing in droplet microfluidic devices |
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| US20110114190A1 (en) | 2009-11-16 | 2011-05-19 | The Hong Kong University Of Science And Technology | Microfluidic droplet generation and/or manipulation with electrorheological fluid |
| US9772261B2 (en) | 2010-02-12 | 2017-09-26 | Fluidion Sas | Passive micro-vessel and sensor |
| BR112012020285B1 (pt) | 2010-02-12 | 2020-12-29 | Dan Angelescu | dispositivo, ferramenta, sistema e método para comunicar sua posição por emissão acústica |
| US20130217113A1 (en) | 2010-07-15 | 2013-08-22 | Advanced Liquid Logic Inc. | System for and methods of promoting cell lysis in droplet actuators |
| US9176504B2 (en) | 2011-02-11 | 2015-11-03 | The Regents Of The University Of California | High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation |
| GB201211342D0 (en) * | 2012-06-26 | 2012-08-08 | Cambridge Entpr Ltd | Microfluidic device |
| US9757726B2 (en) | 2013-03-14 | 2017-09-12 | Inguran, Llc | System for high throughput sperm sorting |
| US10071359B2 (en) | 2013-03-15 | 2018-09-11 | The Regents Of The University Of California | High-speed on demand microfluidic droplet generation and manipulation |
-
2014
- 2014-03-13 US US14/775,611 patent/US10071359B2/en active Active
- 2014-03-13 AU AU2014233699A patent/AU2014233699B2/en not_active Ceased
- 2014-03-13 EP EP14768515.0A patent/EP2972405B1/en active Active
- 2014-03-13 CN CN201480025551.1A patent/CN105452873B/zh active Active
- 2014-03-13 CA CA2909687A patent/CA2909687A1/en not_active Abandoned
- 2014-03-13 JP JP2016502075A patent/JP6461905B2/ja not_active Expired - Fee Related
- 2014-03-13 KR KR1020157029843A patent/KR102168053B1/ko active Active
- 2014-03-13 WO PCT/US2014/026185 patent/WO2014151658A1/en not_active Ceased
-
2018
- 2018-08-28 US US16/115,470 patent/US10780413B2/en active Active
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