WO2001035071A2 - Cell analysis and sorting apparatus for manipulation of cells - Google Patents
Cell analysis and sorting apparatus for manipulation of cells Download PDFInfo
- Publication number
- WO2001035071A2 WO2001035071A2 PCT/US2000/030815 US0030815W WO0135071A2 WO 2001035071 A2 WO2001035071 A2 WO 2001035071A2 US 0030815 W US0030815 W US 0030815W WO 0135071 A2 WO0135071 A2 WO 0135071A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- substrate
- well
- cell
- chamber
- resistor
- Prior art date
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1484—Electro-optical investigation, e.g. flow cytometers microstructural devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1468—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle
- G01N15/147—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/0005—Field flow fractionation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
-
- G01N15/149—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
- G01N2015/1415—Control of particle position
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU15925/01A AU1592501A (en) | 1999-11-10 | 2000-11-10 | Cell analysis and sorting apparatus for manipulation of cells |
EP00978464A EP1236032A2 (en) | 1999-11-10 | 2000-11-10 | Cell analysis and sorting apparatus for manipulation of cells |
JP2001536950A JP2003514236A (en) | 1999-11-10 | 2000-11-10 | Cell analysis and sorting equipment for manipulating cells |
CA002390375A CA2390375A1 (en) | 1999-11-10 | 2000-11-10 | Cell analysis and sorting apparatus for manipulation of cells |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16464399P | 1999-11-10 | 1999-11-10 | |
US60/164,643 | 1999-11-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001035071A2 true WO2001035071A2 (en) | 2001-05-17 |
WO2001035071A3 WO2001035071A3 (en) | 2002-02-21 |
Family
ID=22595424
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/030815 WO2001035071A2 (en) | 1999-11-10 | 2000-11-10 | Cell analysis and sorting apparatus for manipulation of cells |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1236032A2 (en) |
JP (1) | JP2003514236A (en) |
AU (1) | AU1592501A (en) |
CA (1) | CA2390375A1 (en) |
WO (1) | WO2001035071A2 (en) |
Cited By (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002044319A2 (en) * | 2000-11-29 | 2002-06-06 | Picoliter Inc. | Spatially directed ejection of cells from a carrier fluid |
US6893836B2 (en) | 2000-11-29 | 2005-05-17 | Picoliter Inc. | Spatially directed ejection of cells from a carrier fluid |
WO2006080000A1 (en) * | 2005-01-25 | 2006-08-03 | Seng Enterprises Ltd. | Device for the studying individual cells |
US7403647B2 (en) | 2004-09-13 | 2008-07-22 | Seng Enterprises Ltd. | Method for identifying an image of a well in an image of a well-bearing component |
US7405071B2 (en) | 2003-02-27 | 2008-07-29 | Seng Enterprises Ltd. | Method and device for manipulating individual small objects |
US7544805B2 (en) | 2004-02-03 | 2009-06-09 | Chemagis Ltd. | Stable amorphous forms of montelukast sodium |
EP2145610A1 (en) | 2004-03-08 | 2010-01-20 | Allergan Medical S.A. | Closure system for tubular organs |
EP2156888A2 (en) | 2005-05-03 | 2010-02-24 | Oxford Gene Technology IP Limited | Device and process for analysing individual cells |
US7888110B2 (en) | 2003-06-26 | 2011-02-15 | Seng Enterprises Ltd. | Pico liter well holding device and method of making the same |
EP2359689A1 (en) | 2002-09-27 | 2011-08-24 | The General Hospital Corporation | Microfluidic device for cell separation and use thereof |
US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
US8168389B2 (en) | 2006-06-14 | 2012-05-01 | The General Hospital Corporation | Fetal cell analysis using sample splitting |
US8195415B2 (en) | 2008-09-20 | 2012-06-05 | The Board Of Trustees Of The Leland Stanford Junior University | Noninvasive diagnosis of fetal aneuploidy by sequencing |
US8585971B2 (en) | 2005-04-05 | 2013-11-19 | The General Hospital Corporation | Devices and method for enrichment and alteration of cells and other particles |
US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
US9739699B2 (en) | 2007-11-15 | 2017-08-22 | Seng Enterprises Ltd. | Device for the study of living cells |
JP2018504284A (en) * | 2014-11-19 | 2018-02-15 | アイメック・ヴェーゼットウェーImec Vzw | Microbubble generator, system, and manufacturing method |
US9975118B2 (en) | 2007-11-15 | 2018-05-22 | Seng Enterprises Ltd. | Device for the study of living cells |
US10071359B2 (en) | 2013-03-15 | 2018-09-11 | The Regents Of The University Of California | High-speed on demand microfluidic droplet generation and manipulation |
CN108698814A (en) * | 2015-12-30 | 2018-10-23 | 伯克利之光生命科技公司 | Microfluidic device, kit and its method of convection current and displacement for optical drive |
EP3424598A1 (en) | 2006-06-14 | 2019-01-09 | Verinata Health, Inc | Rare cell analysis using sample splitting and dna tags |
US10190082B2 (en) | 2003-06-26 | 2019-01-29 | Seng Enterprises Ltd. | Multiwell plate |
US10226768B2 (en) | 2009-08-08 | 2019-03-12 | The Regents Of The University Of California | Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting |
US10232368B2 (en) | 2011-02-11 | 2019-03-19 | The Regents Of The University Of California | High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation |
US10324011B2 (en) | 2013-03-15 | 2019-06-18 | The Trustees Of Princeton University | Methods and devices for high throughput purification |
US10591391B2 (en) | 2006-06-14 | 2020-03-17 | Verinata Health, Inc. | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
US10704090B2 (en) | 2006-06-14 | 2020-07-07 | Verinata Health, Inc. | Fetal aneuploidy detection by sequencing |
CN112567224A (en) * | 2018-08-15 | 2021-03-26 | 索尼公司 | Particle acquisition method, particle capture chamber and particle analysis system |
US11142746B2 (en) | 2013-03-15 | 2021-10-12 | University Of Maryland, Baltimore | High efficiency microfluidic purification of stem cells to improve transplants |
US11229912B2 (en) | 2018-03-27 | 2022-01-25 | Hewlett-Packard Development Company, L.P. | Particle separation |
US11493428B2 (en) | 2013-03-15 | 2022-11-08 | Gpb Scientific, Inc. | On-chip microfluidic processing of particles |
US11492585B2 (en) | 2019-05-31 | 2022-11-08 | Canon Medical Systems Corporation | Cell identification system and cell identification method |
US11612890B2 (en) | 2019-04-30 | 2023-03-28 | Berkeley Lights, Inc. | Methods for encapsulating and assaying cells |
Families Citing this family (2)
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JP2011000079A (en) * | 2009-06-19 | 2011-01-06 | Univ Of Tokyo | Method for operating particle and micro fluid device |
JP6334274B2 (en) * | 2014-06-03 | 2018-05-30 | 積水化学工業株式会社 | Suspension transfer method |
Citations (4)
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US4894343A (en) * | 1986-11-19 | 1990-01-16 | Hitachi, Ltd. | Chamber plate for use in cell fusion and a process for production thereof |
US5506141A (en) * | 1982-05-10 | 1996-04-09 | Bar-Ilan University | Apertured cell carrier |
DE19712309A1 (en) * | 1996-11-16 | 1998-05-20 | Nmi Univ Tuebingen | Microelement arrangement, method for contacting cells in a liquid environment and method for producing a microelement arrangement |
WO1999031503A1 (en) * | 1997-12-17 | 1999-06-24 | Horst Vogel | Positioning and electrophysiological characterization of individual cells and reconstituted membrane systems on microstructured carriers |
-
2000
- 2000-11-10 AU AU15925/01A patent/AU1592501A/en not_active Abandoned
- 2000-11-10 JP JP2001536950A patent/JP2003514236A/en not_active Withdrawn
- 2000-11-10 WO PCT/US2000/030815 patent/WO2001035071A2/en active Application Filing
- 2000-11-10 EP EP00978464A patent/EP1236032A2/en not_active Withdrawn
- 2000-11-10 CA CA002390375A patent/CA2390375A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5506141A (en) * | 1982-05-10 | 1996-04-09 | Bar-Ilan University | Apertured cell carrier |
US4894343A (en) * | 1986-11-19 | 1990-01-16 | Hitachi, Ltd. | Chamber plate for use in cell fusion and a process for production thereof |
DE19712309A1 (en) * | 1996-11-16 | 1998-05-20 | Nmi Univ Tuebingen | Microelement arrangement, method for contacting cells in a liquid environment and method for producing a microelement arrangement |
WO1999031503A1 (en) * | 1997-12-17 | 1999-06-24 | Horst Vogel | Positioning and electrophysiological characterization of individual cells and reconstituted membrane systems on microstructured carriers |
Cited By (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002044319A3 (en) * | 2000-11-29 | 2004-04-08 | Picoliter Inc | Spatially directed ejection of cells from a carrier fluid |
US6893836B2 (en) | 2000-11-29 | 2005-05-17 | Picoliter Inc. | Spatially directed ejection of cells from a carrier fluid |
WO2002044319A2 (en) * | 2000-11-29 | 2002-06-06 | Picoliter Inc. | Spatially directed ejection of cells from a carrier fluid |
EP2359689A1 (en) | 2002-09-27 | 2011-08-24 | The General Hospital Corporation | Microfluidic device for cell separation and use thereof |
US10081014B2 (en) | 2002-09-27 | 2018-09-25 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
US8895298B2 (en) | 2002-09-27 | 2014-11-25 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
US11052392B2 (en) | 2002-09-27 | 2021-07-06 | The General Hospital Corporation | Microfluidic device for cell separation and uses thereof |
US7405071B2 (en) | 2003-02-27 | 2008-07-29 | Seng Enterprises Ltd. | Method and device for manipulating individual small objects |
US7888110B2 (en) | 2003-06-26 | 2011-02-15 | Seng Enterprises Ltd. | Pico liter well holding device and method of making the same |
US10190082B2 (en) | 2003-06-26 | 2019-01-29 | Seng Enterprises Ltd. | Multiwell plate |
US7544805B2 (en) | 2004-02-03 | 2009-06-09 | Chemagis Ltd. | Stable amorphous forms of montelukast sodium |
EP2145610A1 (en) | 2004-03-08 | 2010-01-20 | Allergan Medical S.A. | Closure system for tubular organs |
US7403647B2 (en) | 2004-09-13 | 2008-07-22 | Seng Enterprises Ltd. | Method for identifying an image of a well in an image of a well-bearing component |
WO2006080000A1 (en) * | 2005-01-25 | 2006-08-03 | Seng Enterprises Ltd. | Device for the studying individual cells |
US10786817B2 (en) | 2005-04-05 | 2020-09-29 | The General Hospital Corporation | Devices and method for enrichment and alteration of cells and other particles |
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JP2003514236A (en) | 2003-04-15 |
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EP1236032A2 (en) | 2002-09-04 |
AU1592501A (en) | 2001-06-06 |
CA2390375A1 (en) | 2001-05-17 |
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