|
ATE180280T1
(de)
|
1991-03-05 |
1999-06-15 |
Wellcome Found |
Expression rekombinanter proteine in attenuierten bakterien
|
|
US5962406A
(en)
|
1991-10-25 |
1999-10-05 |
Immunex Corporation |
Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same
|
|
US5981724A
(en)
|
1991-10-25 |
1999-11-09 |
Immunex Corporation |
DNA encoding CD40 ligand, a cytokine that binds CD40
|
|
KR100283541B1
(ko)
|
1991-10-25 |
2001-03-02 |
크리스토퍼 엘. 와이트, 스코트 지. 홀퀴스트, 스티븐 엘. 말라스카 |
신규 사이토킨
|
|
US5716805A
(en)
|
1991-10-25 |
1998-02-10 |
Immunex Corporation |
Methods of preparing soluble, oligomeric proteins
|
|
US7405270B2
(en)
|
1991-10-25 |
2008-07-29 |
Immunex Corporation |
CD40-Ligand lacking native-pattern glycosylation
|
|
US5961974A
(en)
|
1991-10-25 |
1999-10-05 |
Immunex Corporation |
Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same
|
|
US5540926A
(en)
|
1992-09-04 |
1996-07-30 |
Bristol-Myers Squibb Company |
Soluble and its use in B cell stimulation
|
|
CA2143299A1
(en)
|
1992-09-04 |
1994-03-17 |
University Of Saskatchewan |
Novel bacterial vaccines using vaccine strains of pathogenic bacteria
|
|
US5565321A
(en)
|
1993-01-22 |
1996-10-15 |
Immunex Corporation |
Detection of mutations in a CD40 ligand gene
|
|
WO1995014487A1
(en)
|
1993-11-24 |
1995-06-01 |
The Australian National University |
Treatment of viral disease with cd40l peptide
|
|
DK0763057T3
(da)
|
1994-04-28 |
2006-03-27 |
Boehringer Ingelheim Pharma |
Fremgangsmåde til proliferering og differentiering af B celler og anvendelse deraf
|
|
AU699291B2
(en)
|
1995-03-01 |
1998-11-26 |
Immunex Corporation |
Method for stimulating an immune response
|
|
MX9709447A
(es)
|
1995-06-07 |
1998-02-28 |
Immunex Corp |
Nueva muteina cd4ol.
|
|
US6479258B1
(en)
|
1995-12-07 |
2002-11-12 |
Diversa Corporation |
Non-stochastic generation of genetic vaccines
|
|
US6713279B1
(en)
|
1995-12-07 |
2004-03-30 |
Diversa Corporation |
Non-stochastic generation of genetic vaccines and enzymes
|
|
US6306387B1
(en)
|
1997-05-29 |
2001-10-23 |
The Research Foundation Of State University Of New York |
Antigen delivery system
|
|
US20030045492A1
(en)
|
1997-08-13 |
2003-03-06 |
Tang De-Chu C. |
Vaccination by topical application of recombinant vectors
|
|
US6969609B1
(en)
|
1998-12-09 |
2005-11-29 |
The United States Of America As Represented By The Department Of Health And Human Serivces |
Recombinant vector expressing multiple costimulatory molecules and uses thereof
|
|
CA2223225A1
(en)
|
1997-11-28 |
1999-05-28 |
Canadian Red Cross Society |
Method for inhibiting in vivo immune response
|
|
JP2001526241A
(ja)
|
1997-12-19 |
2001-12-18 |
イミュネックス・コーポレーション |
Ｈｉｖ感染に対する感受性を低下させるための方法
|
|
GB9806449D0
(en)
|
1998-03-25 |
1998-05-27 |
Peptide Therapeutics Ltd |
Attenuated bacteria useful in vaccines
|
|
US6190669B1
(en)
|
1998-05-13 |
2001-02-20 |
University Of Maryland, Baltimore |
Attenuated mutants of salmonella which constitutively express the Vi antigen
|
|
IT1299583B1
(it)
|
1998-05-19 |
2000-03-16 |
Vander Way Limited |
Uso di proteine hmg-i per la preparazione di medicamenti ad attivita' citotossica
|
|
WO2000014240A2
(en)
|
1998-09-04 |
2000-03-16 |
Creatogen Aktiengesellschaft |
Attenuated salmonella sp12 mutants as antigen carriers
|
|
US7300774B1
(en)
|
1999-12-09 |
2007-11-27 |
The Regents Of The University Of California |
Multimeric fusion proteins of the TNF superfamily ligands
|
|
JP2003508016A
(ja)
|
1999-04-16 |
2003-03-04 |
エフ．ホフマン−ラ ロシュ アーゲー |
Ｃｄ４０／ｃｄ４０ｌキメラポリペプチドをコードする核酸、それらの生成方法及びそれらの使用
|
|
EP1067194A1
(en)
|
1999-04-16 |
2001-01-10 |
F. Hoffmann-La Roche Ag |
Vectors containing a gene coding for CD40 and/or CD40L under the control of a cytokine-inducible promoter which is a human acute phase amyloid A gene promoter. Methods for their production and uses thereof
|
|
US7803765B2
(en)
|
1999-05-05 |
2010-09-28 |
Phylogica Limited |
Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom
|
|
EP1246643A4
(en)
|
1999-10-14 |
2005-05-11 |
Jeffery A Ledbetter |
DNA VACCINES ENCODING ANTIGEN ASSOCIATED WITH CD40-BINDING DOMAIN
|
|
MXPA00012796A
(es)
|
1999-12-28 |
2002-05-23 |
Akzo Nobel Nv |
Vacuna de salmonella.
|
|
DE60136334D1
(en)
|
2000-02-02 |
2008-12-11 |
Us Health |
Cd40-ligand als adjuvant für respiratorisches syncytialvirus-impfstoff
|
|
AU5695701A
(en)
|
2000-03-17 |
2001-10-03 |
Upjohn Co |
Salmonella vaccine materials and methods
|
|
GB0015426D0
(en)
|
2000-06-24 |
2000-08-16 |
Univ Southampton |
Method for generating soluble highly multimeric proteins
|
|
AU2001273009A1
(en)
|
2000-06-26 |
2002-01-08 |
Maxygen, Inc. |
Methods and compositions for developing spore display systems for medicinal and industrial applications
|
|
AU2002221780A1
(en)
|
2000-10-31 |
2002-05-15 |
F.Hoffmann-La Roche Ag |
Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
|
|
EP1407004B1
(en)
|
2001-05-15 |
2009-08-05 |
Ortho-McNeil-Janssen Pharmaceuticals, Inc. |
Ex-vivo priming for generating cd40-ligand specific cytotoxic t lymphocytes to treat autoimmune and allergic disease
|
|
BR0209689A
(pt)
|
2001-05-15 |
2006-02-07 |
Long Island Jewish Res Inst |
Uso de fragmento de hmg como agente anti-inflamatório
|
|
US7220723B2
(en)
|
2001-05-15 |
2007-05-22 |
The Feinstein Institute For Medical Research |
Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
|
|
AU2002316560B2
(en)
|
2001-07-06 |
2008-05-01 |
Abic Biological Laboratories Ltd |
Nucleic acids encoding a recombinant 250 kDa antigen from Sporozoites/Merozoites of Eimeria maxima and their uses
|
|
ZA200400479B
(en)
|
2001-07-06 |
2006-05-31 |
Abic Biolog Lab Teva |
Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use
|
|
ITMI20011986A1
(it)
|
2001-09-25 |
2003-03-25 |
San Raffaele Centro Fond |
Metodo e composizione per l'attivazione di cellule presentanti l'antigene
|
|
US7378089B2
(en)
|
2001-10-02 |
2008-05-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Gene therapy for the prevention of autoimmune disease
|
|
CA2470640A1
(en)
|
2001-12-19 |
2003-06-26 |
Alcedo Biotech Gmbh |
Use of hmgb proteins and nucleic acids that code therefor
|
|
PL208287B1
(pl)
|
2001-12-21 |
2011-04-29 |
Immunex Corp |
Polipeptyd fuzyjny, sposób jego wytwarzania oraz kodujący go kwas nukleinowy, komórka gospodarza, rekombinowany wektor oraz sposób jego konstruowania
|
|
KR100965026B1
(ko)
|
2002-02-13 |
2010-06-21 |
이뮤놀로지 래보러토리스 인코포레이티드 |
미생물 감염증을 치료하기 위한 조성물 및 방법
|
|
US6923958B2
(en)
|
2002-03-02 |
2005-08-02 |
The Scripps Research Institute |
DNA vaccines encoding CEA and a CD40 ligand and methods of use thereof
|
|
WO2003096812A1
(en)
|
2002-04-15 |
2003-11-27 |
Washington University |
Regulated attenuation of live vaccines to enhance cross protective immunogenicity
|
|
US7495090B2
(en)
|
2002-05-23 |
2009-02-24 |
The Regents Of The University Of California |
Nucleic acids encoding chimeric CD154 polypeptides
|
|
AU2003295653B2
(en)
|
2002-11-20 |
2007-08-16 |
The Feinstein Institute Of Medical Research |
Use of HMGB polypeptides for increasing immune responses
|
|
US20040156851A1
(en)
|
2002-11-20 |
2004-08-12 |
Critical Therapeutics, Inc. |
HMGB1 combination therapies
|
|
US20040141948A1
(en)
|
2002-11-20 |
2004-07-22 |
Critical Therapeutics, Inc. |
Use of HMGB fragments as anti-inflammatory agents
|
|
WO2004046345A2
(en)
|
2002-11-20 |
2004-06-03 |
Critical Therapeutics, Inc. |
Use of hmgb fragments as anti-inflammatory agents
|
|
US20050181994A1
(en)
|
2003-01-06 |
2005-08-18 |
Xencor, Inc. |
Novel variants of CD40L protein
|
|
US20060014248A1
(en)
|
2003-01-06 |
2006-01-19 |
Xencor, Inc. |
TNF super family members with altered immunogenicity
|
|
US7696169B2
(en)
|
2003-06-06 |
2010-04-13 |
The Feinstein Institute For Medical Research |
Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
|
|
US7754209B2
(en)
|
2003-07-26 |
2010-07-13 |
Trubion Pharmaceuticals |
Binding constructs and methods for use thereof
|
|
WO2005025604A2
(en)
|
2003-09-10 |
2005-03-24 |
The General Hospital Corporation |
Use of hmgb and hmgb fragments to decrease specific immune response
|
|
WO2005035570A2
(en)
|
2003-10-10 |
2005-04-21 |
Xencor, Inc. |
Variants of cd40l protein
|
|
WO2005058950A2
(en)
|
2003-12-11 |
2005-06-30 |
Sidney Kimmel Cancer Center |
Methods for generating immunity to antigen
|
|
US8828957B2
(en)
|
2003-12-11 |
2014-09-09 |
Microvax, Llc |
Methods for generating immunity to antigen
|
|
WO2005113598A2
(en)
|
2004-05-21 |
2005-12-01 |
Xencor, Inc. |
Tnf super family members with altered immunogenicity
|
|
WO2006083301A2
(en)
|
2004-06-17 |
2006-08-10 |
Medimmune, Inc. |
Immunogenic compositions comprising hmgb1 polypeptides
|
|
EP1814576A2
(en)
|
2004-07-20 |
2007-08-08 |
Critical Therapeutics, Inc. |
Combination therapies of hmgb and complement inhibitors against inflammation
|
|
CN101044160A
(zh)
*
|
2004-08-19 |
2007-09-26 |
蛋白质组系统知识产权有限公司 |
结核分支杆菌感染的诊断和治疗方法及所用试剂
|
|
US8513008B2
(en)
|
2004-10-07 |
2013-08-20 |
Argos Therapeutics, Inc. |
Mature dendritic cell compositions and methods for culturing same
|
|
US20080145931A1
(en)
|
2004-10-07 |
2008-06-19 |
Argos Therapeutics, Inc. |
Mature Dendritic Cell Compositions and Methods of Culturing Same
|
|
WO2006105972A1
(en)
|
2005-04-07 |
2006-10-12 |
Universite Libre De Bruxelles |
Transgenic organism expressing cd40l and uses thereof
|
|
US7833979B2
(en)
|
2005-04-22 |
2010-11-16 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
|
WO2006130525A2
(en)
|
2005-05-31 |
2006-12-07 |
Sidney Kimmel Cancer Center |
Methods for immunotherapy of cancer
|
|
EP1909834A2
(en)
|
2005-07-18 |
2008-04-16 |
Critical Therapeutics, Inc. |
Use of hmgb1 antagonists for the treatment of inflammatory skin conditions
|
|
JP2009511452A
(ja)
|
2005-10-07 |
2009-03-19 |
プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ |
Ｃ型肝炎の予防および治療のための免疫刺激物質の組合せ
|
|
AU2006311752A1
(en)
|
2005-11-07 |
2007-05-18 |
Sidney Kimmel Cancer Center |
CD40 ligand fusion protein vaccine
|
|
WO2007054658A1
(en)
|
2005-11-14 |
2007-05-18 |
King's College London |
Control of immune responses
|
|
WO2007130725A2
(en)
|
2006-02-06 |
2007-11-15 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Use of hmgb1 for protection against ischemia reperfusion injury
|
|
WO2007103048A2
(en)
|
2006-03-01 |
2007-09-13 |
Regents Of The University Of Colorado |
Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity
|
|
US8802419B2
(en)
|
2006-03-02 |
2014-08-12 |
University Of Massachusetts |
Modified pathogens for use as vaccines
|
|
EP2857038B1
(en)
|
2006-09-18 |
2019-04-10 |
The Board of Trustees of the University of Arkansas |
Compositions and methods of enhancing immune responses
|
|
WO2008109825A2
(en)
|
2007-03-08 |
2008-09-12 |
Mayo Foundation For Medical Education And Research |
Inducing immune-mediated tumor cell death
|
|
CN101024076B
(zh)
|
2007-03-29 |
2010-08-18 |
中国农业大学 |
球虫的新用途
|
|
US9125854B2
(en)
|
2007-10-30 |
2015-09-08 |
The Board Of Trustees Of The University Of Arkansas |
Compositions and methods of enhancing immune responses to flagellated bacterium
|
|
PT2214701T
(pt)
*
|
2007-11-01 |
2016-11-02 |
Univ Guelph |
Composições e métodos de potenciar respostas imunes a eimeria
|
|
CN101234196A
(zh)
|
2007-11-30 |
2008-08-06 |
吉林大学 |
球虫重组卡介苗及制备方法
|
|
JP5710482B2
(ja)
|
2008-09-11 |
2015-04-30 |
アンスティテュ・パストゥール |
Ｈｍｇｂ１依存型誘発のｈｉｖ−１複製および持続の調節によるヒト免疫不全ウイルス感染の監視および阻害
|
|
CA2743262C
(en)
|
2008-11-13 |
2021-11-02 |
Intervet International B.V. |
Eimeria vaccine for turkeys
|
|
US20100150958A1
(en)
|
2008-12-15 |
2010-06-17 |
Vectogen Pty Ltd. |
Methods and Compositions for Use of a Coccidiosis Vaccine
|
|
JP2011072284A
(ja)
*
|
2009-10-01 |
2011-04-14 |
Mitsubishi Chemicals Corp |
抗体の製造方法及びそれに用いる免疫原性組成物
|
|
NO2525817T3
(enExample)
*
|
2010-01-21 |
2018-01-06 |
|
|
|
BR112012031211A2
(pt)
|
2010-06-09 |
2018-01-30 |
Univ Arkansas |
métodos e vacina para reduzir a infecção causada pelo campylobacter
|
|
AU2013338153B2
(en)
|
2012-10-29 |
2018-06-21 |
The Board Of Trustees Of The University Of Arkansas |
Novel mucosal adjuvants and delivery systems
|
|
EP2956165B1
(en)
|
2013-02-14 |
2019-09-11 |
The Board of Trustees of the University of Arkansas |
Compositions and methods of enhancing immune responses to eimeria or limiting eimeria infection
|
|
CN105142653B
(zh)
|
2013-03-15 |
2019-11-15 |
阿肯色大学评议会 |
增强对肠病原体免疫应答的组合物和方法
|