|
JP3101690B2
(ja)
|
1987-03-18 |
2000-10-23 |
エス・ビィ・2・インコーポレイテッド |
変性抗体の、または変性抗体に関する改良
|
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
US5468468A
(en)
|
1989-02-09 |
1995-11-21 |
The United States Of America, As Represented By The Secretary Of The Department Of Health & Human Services |
Method for making a monoclonal antibody, monoclonal antibodies to α PD
|
|
DE4205148A1
(de)
|
1991-05-25 |
1993-01-21 |
Boehringer Mannheim Gmbh |
Monoklonale antikoerper gegen c-kit
|
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
|
US6696548B2
(en)
|
1993-12-03 |
2004-02-24 |
St. Jude Children's Research Hospital |
Antibodies for recognition of alk protein tyrosine/kinase receptor
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5686292A
(en)
|
1995-06-02 |
1997-11-11 |
Genentech, Inc. |
Hepatocyte growth factor receptor antagonist antibodies and uses thereof
|
|
DE19638745C2
(de)
|
1996-09-11 |
2001-05-10 |
Schering Ag |
Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR)
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US20020136721A1
(en)
*
|
1998-02-17 |
2002-09-26 |
Schwall Ralph H. |
Hepatocyte growth factor receptor antagonists and uses thereof
|
|
DK1071700T3
(da)
|
1998-04-20 |
2010-06-07 |
Glycart Biotechnology Ag |
Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet
|
|
CA2704600C
(en)
|
1999-04-09 |
2016-10-25 |
Kyowa Kirin Co., Ltd. |
A method for producing antibodies with increased adcc activity
|
|
AU5286999A
(en)
|
1999-07-23 |
2001-02-13 |
Glaxo Group Limited |
Combination of an anti-ep-cam antibody with a chemotherapeutic agent
|
|
US8071072B2
(en)
|
1999-10-08 |
2011-12-06 |
Hoffmann-La Roche Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD44
|
|
EP1229125A4
(en)
|
1999-10-19 |
2005-06-01 |
Kyowa Hakko Kogyo Kk |
PROCESS FOR PREPARING A POLYPEPTIDE
|
|
JP4132547B2
(ja)
|
2000-03-01 |
2008-08-13 |
富士フイルム株式会社 |
画像形成材料及びそれを用いた平版印刷版原版
|
|
US20020119148A1
(en)
|
2000-09-01 |
2002-08-29 |
Gerritsen Mary E. |
ErbB4 antagonists
|
|
US7101976B1
(en)
|
2000-09-12 |
2006-09-05 |
Purdue Research Foundation |
EphA2 monoclonal antibodies and methods of making and using same
|
|
CA2953239A1
(en)
|
2000-10-06 |
2002-04-18 |
Kyowa Hakko Kirin Co., Ltd. |
Antibody composition-producing cell
|
|
CA2424977C
(en)
|
2000-10-06 |
2008-03-18 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for purifying antibody
|
|
ME00502B
(me)
|
2001-01-05 |
2011-10-10 |
Amgen Fremont Inc |
Antitjela za insulinu sličan receptor faktora i rasta
|
|
AU2002307037B2
(en)
|
2001-04-02 |
2008-08-07 |
Biogen Idec Inc. |
Recombinant antibodies coexpressed with GnTIII
|
|
EP1383785B1
(en)
|
2001-05-03 |
2011-03-16 |
Merck Patent GmbH |
Recombinant tumor specific antibody and use thereof
|
|
US6972324B2
(en)
|
2001-05-18 |
2005-12-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Antibodies specific for CD44v6
|
|
CA2450793A1
(en)
|
2001-06-20 |
2002-12-27 |
Prochon Biotech Ltd. |
Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
|
|
EP1406931A2
(en)
|
2001-07-19 |
2004-04-14 |
Universität Zürich |
Modification of human variable domains
|
|
CA2463879C
(en)
|
2001-10-25 |
2012-12-04 |
Genentech, Inc. |
Glycoprotein compositions
|
|
EP1469878B1
(en)
|
2002-01-31 |
2011-03-23 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Fgfr agonists
|
|
EP2298346A3
(en)
|
2002-03-04 |
2011-11-16 |
Imclone LLC |
Human antibodies specific to kdr and uses thereof
|
|
JP4585968B2
(ja)
|
2002-05-10 |
2010-11-24 |
パーデュー・リサーチ・ファウンデーション |
EphA2アゴニストモノクローナル抗体およびその使用法
|
|
US20080008713A1
(en)
|
2002-06-28 |
2008-01-10 |
Domantis Limited |
Single domain antibodies against tnfr1 and methods of use therefor
|
|
US7232888B2
(en)
|
2002-07-01 |
2007-06-19 |
Massachusetts Institute Of Technology |
Antibodies against tumor surface antigens
|
|
BRPI0407446A
(pt)
|
2003-02-13 |
2006-01-31 |
Pharmacia Corp |
Anticorpos para c-met para o tratamento de cânceres
|
|
ITMI20031127A1
(it)
|
2003-06-05 |
2004-12-06 |
Uni Degli Studi Del Piemont E Orientale Am |
Anticorpi anti-hgf-r e loro uso
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
AU2004266159A1
(en)
|
2003-08-22 |
2005-03-03 |
Biogen Idec Ma Inc. |
Improved antibodies having altered effector function and methods for making the same
|
|
EP2060270A3
(en)
|
2003-10-16 |
2009-12-09 |
Imclone LLC |
Fibroblast growth factor receptor-1 inhibitors and methods of treatment thereof
|
|
WO2005063815A2
(en)
|
2003-11-12 |
2005-07-14 |
Biogen Idec Ma Inc. |
Fcϝ receptor-binding polypeptide variants and methods related thereto
|
|
WO2005047327A2
(en)
|
2003-11-12 |
2005-05-26 |
Biogen Idec Ma Inc. |
NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO
|
|
PT1718677E
(pt)
|
2003-12-19 |
2012-07-18 |
Genentech Inc |
Fragmentos de anticorpo monovalentes úteis como agentes terapêuticos
|
|
DK1771482T3
(da)
|
2004-07-22 |
2014-10-20 |
Genentech Inc |
HER2-antistofsammensætning
|
|
CA2575402A1
(en)
|
2004-08-05 |
2006-02-09 |
Genentech, Inc. |
Humanized anti-cmet antagonists
|
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
|
CN101155830B
(zh)
|
2005-02-04 |
2014-06-18 |
雷文生物技术公司 |
结合epha2的抗体及其使用方法
|
|
PL1871805T3
(pl)
|
2005-02-07 |
2020-03-31 |
Roche Glycart Ag |
Cząsteczki wiążące antygen, które wiążą egfr, wektory kodujące te cząsteczki oraz ich zastosowania
|
|
NZ561211A
(en)
|
2005-03-25 |
2011-03-31 |
Genentech Inc |
Methods and compositions for modulating hyperstabilized C-met
|
|
BRPI0611445A2
(pt)
|
2005-05-09 |
2010-09-08 |
Glycart Biotechnology Ag |
molécula de ligação a antìgeno glicomanipulada, polinucleotìdeo, polipeptìdeo, vetor, célula hospedeira, método para produção, uso e composição farmacêutica
|
|
CA2612449A1
(en)
|
2005-06-17 |
2006-12-28 |
Imclone Systems Incorporated |
Receptor antagonists for treatment of metastatic bone cancer
|
|
AR056857A1
(es)
|
2005-12-30 |
2007-10-24 |
U3 Pharma Ag |
Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
|
|
AU2007213920B2
(en)
|
2006-02-09 |
2013-08-29 |
Amgen Research (Munich) Gmbh |
Treatment of metastatic breast cancer
|
|
CA2646508A1
(en)
|
2006-03-17 |
2007-09-27 |
Biogen Idec Ma Inc. |
Stabilized polypeptide compositions
|
|
US8101727B2
(en)
|
2006-03-30 |
2012-01-24 |
Novartis Ag |
Compositions and methods of use for antibodies of c-Met
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之c-kit抗體
|
|
BRPI0710971A2
(pt)
|
2006-04-28 |
2011-05-31 |
Esbatech Ag |
anticorpos que se ligam ao domìnio extracelular do receptor tirosina cinase alk,seu uso, vetor de expressão,método para produção de um antcorpo, vacina e epìtodo de alk
|
|
EP2094733A1
(en)
|
2006-11-03 |
2009-09-02 |
U3 Pharma GmbH |
Fgfr4 antibodies
|
|
UY30776A1
(es)
|
2006-12-21 |
2008-07-03 |
Medarex Inc |
Anticuerpos cd44
|
|
KR101598229B1
(ko)
|
2007-02-16 |
2016-02-26 |
메리맥 파마슈티컬즈, 인크. |
Erbb3에 대한 항체 및 이의 용도
|
|
ES2368764T3
(es)
|
2007-03-19 |
2011-11-22 |
Universität Stuttgart |
ANTAGONISTAS SELECTIVOS DE huTNFR1.
|
|
CA2682390A1
(en)
|
2007-04-17 |
2008-10-30 |
Imclone Llc |
Pdgfr.beta.-specific inhibitors
|
|
EP2144930A1
(en)
*
|
2007-04-18 |
2010-01-20 |
ZymoGenetics, Inc. |
Single chain fc, methods of making and methods of treatment
|
|
WO2008131575A2
(en)
|
2007-04-27 |
2008-11-06 |
Esbatech Ag |
Anti-alk antibodies suitable for treating metastatic cancers or tumors
|
|
EP2158318A2
(en)
|
2007-05-14 |
2010-03-03 |
Biogen Idec MA, Inc. |
Single-chain fc (scfc) regions, binding polypeptides comprising same, and methods related thereto
|
|
EP2014681A1
(en)
|
2007-07-12 |
2009-01-14 |
Pierre Fabre Medicament |
Novel antibodies inhibiting c-met dimerization, and uses thereof
|
|
CA2700815A1
(en)
|
2007-09-27 |
2009-04-02 |
Viventia Biotech Inc. |
Optimized nucleic acid sequences for the expression of vb4-845
|
|
JP5769969B2
(ja)
|
2007-11-12 |
2015-08-26 |
ユー3・ファーマ・ゲーエムベーハー |
Axl抗体
|
|
CL2008003449A1
(es)
|
2007-11-21 |
2010-02-19 |
Imclone Llc |
Anticuerpo o fragmentos del mismo contra el receptor de proteína estimulante de macrófagos/ron; composición farmacéutica que lo comprende; uso para inhibir angiogénesis, crecimiento tumoral, proliferación, migración e invasión de células tumorales, activación de ron o fosforilación de mapk y/o akt; y uso para tratar cáncer.
|
|
JP6157046B2
(ja)
|
2008-01-07 |
2017-07-05 |
アムジェン インコーポレイテッド |
静電的ステアリング(electrostaticsteering)効果を用いた抗体Fcヘテロ二量体分子を作製するための方法
|
|
JP2011509687A
(ja)
|
2008-01-22 |
2011-03-31 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
Ron抗体およびその使用
|
|
MX2010011145A
(es)
*
|
2008-04-11 |
2011-04-11 |
Merrimack Pharmaceuticals Inc |
Enlazadores de la albumina de suero humana y conjugados de la misma.
|
|
US20100009390A1
(en)
|
2008-05-09 |
2010-01-14 |
The Regents Of The University Of California |
Mutant antibodies with high affinity for egfr
|
|
EP2313435A4
(en)
|
2008-07-01 |
2012-08-08 |
Aveo Pharmaceuticals Inc |
FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) BINDING PROTEINS
|
|
WO2010064090A1
(en)
|
2008-12-02 |
2010-06-10 |
Pierre Fabre Medicament |
Process for the modulation of the antagonistic activity of a monoclonal antibody
|
|
EP2417164A1
(en)
|
2009-04-07 |
2012-02-15 |
Roche Glycart AG |
Bispecific anti-erbb-2/anti-c-met antibodies
|
|
KR20120024763A
(ko)
|
2009-05-15 |
2012-03-14 |
추가이 세이야쿠 가부시키가이샤 |
항axl 항체
|
|
GB0909904D0
(en)
*
|
2009-06-09 |
2009-07-22 |
Affitech As |
Product
|
|
WO2011028952A1
(en)
*
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
EP2496601B1
(en)
|
2009-11-05 |
2017-06-07 |
F. Hoffmann-La Roche AG |
Methods and composition for secretion of heterologous polypeptides
|
|
PT3904391T
(pt)
*
|
2010-03-10 |
2024-10-14 |
Genmab As |
Anticorpos monoclonais contra c-met
|
|
MX343227B
(es)
|
2010-04-09 |
2016-10-28 |
Aveo Pharmaceuticals Inc |
Anticuerpos anti-erbb3.
|
|
RU2012153241A
(ru)
|
2010-05-11 |
2014-06-20 |
Авео Фармасьютикалз, Инк. |
Антитела к fgfr2
|
|
RU2577986C2
(ru)
|
2010-06-18 |
2016-03-20 |
Дженентек, Инк. |
Антитела против axl и способы их применения
|
|
AR082194A1
(es)
|
2010-07-06 |
2012-11-21 |
Aveo Pharmaceuticals Inc |
Anticuerpos anti-ron
|
|
TW201217527A
(en)
|
2010-07-09 |
2012-05-01 |
Biogen Idec Hemophilia Inc |
Processable single chain molecules and polypeptides made using same
|
|
CA2843158A1
(en)
|
2011-08-26 |
2013-03-07 |
Merrimack Pharmaceuticals, Inc. |
Tandem fc bispecific antibodies
|
|
HK1220465A1
(zh)
*
|
2013-03-06 |
2017-05-05 |
Merrimack Pharmaceuticals, Inc. |
抗c-met串联fc双特异性抗体
|