JP2016507723A5 - - Google Patents
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- JP2016507723A5 JP2016507723A5 JP2015545504A JP2015545504A JP2016507723A5 JP 2016507723 A5 JP2016507723 A5 JP 2016507723A5 JP 2015545504 A JP2015545504 A JP 2015545504A JP 2015545504 A JP2015545504 A JP 2015545504A JP 2016507723 A5 JP2016507723 A5 JP 2016507723A5
- Authority
- JP
- Japan
- Prior art keywords
- analysis
- subject
- proteins
- polyp
- adenoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 41
- 238000004458 analytical method Methods 0.000 claims 13
- 108090000623 proteins and genes Proteins 0.000 claims 13
- 102000004169 proteins and genes Human genes 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 102000004196 processed proteins & peptides Human genes 0.000 claims 9
- 208000003200 Adenoma Diseases 0.000 claims 7
- 206010001233 Adenoma benign Diseases 0.000 claims 7
- 208000037062 Polyps Diseases 0.000 claims 7
- 206010009944 Colon cancer Diseases 0.000 claims 6
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 6
- 206010048832 Colon adenoma Diseases 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 239000012472 biological sample Substances 0.000 claims 5
- 230000001900 immune effect Effects 0.000 claims 5
- 230000035945 sensitivity Effects 0.000 claims 5
- 208000004804 Adenomatous Polyps Diseases 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 238000004949 mass spectrometry Methods 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 3
- 210000001072 colon Anatomy 0.000 claims 3
- 201000002758 colorectal adenoma Diseases 0.000 claims 3
- 208000014081 polyp of colon Diseases 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 206010058314 Dysplasia Diseases 0.000 claims 2
- 238000002965 ELISA Methods 0.000 claims 2
- 206010048829 Rectal adenoma Diseases 0.000 claims 2
- 230000001413 cellular effect Effects 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 2
- 230000009257 reactivity Effects 0.000 claims 2
- 201000003780 rectum adenoma Diseases 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 238000004611 spectroscopical analysis Methods 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 102100022524 Alpha-1-antichymotrypsin Human genes 0.000 claims 1
- 102100040896 Growth/differentiation factor 15 Human genes 0.000 claims 1
- 101000678026 Homo sapiens Alpha-1-antichymotrypsin Proteins 0.000 claims 1
- 101000893549 Homo sapiens Growth/differentiation factor 15 Proteins 0.000 claims 1
- 101000869480 Homo sapiens Serum amyloid A-1 protein Proteins 0.000 claims 1
- 101100078144 Mus musculus Msrb1 gene Proteins 0.000 claims 1
- -1 PSGL Proteins 0.000 claims 1
- 102100032277 Serum amyloid A-1 protein Human genes 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 208000011769 benign colon neoplasm Diseases 0.000 claims 1
- 239000012503 blood component Substances 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 238000002052 colonoscopy Methods 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 210000000416 exudates and transudate Anatomy 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
- 238000003119 immunoblot Methods 0.000 claims 1
- 230000000951 immunodiffusion Effects 0.000 claims 1
- 238000000760 immunoelectrophoresis Methods 0.000 claims 1
- 238000001114 immunoprecipitation Methods 0.000 claims 1
- 238000012744 immunostaining Methods 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 210000002751 lymph Anatomy 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 230000002285 radioactive effect Effects 0.000 claims 1
- 238000003127 radioimmunoassay Methods 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261732024P | 2012-11-30 | 2012-11-30 | |
| US61/732,024 | 2012-11-30 | ||
| US201361772979P | 2013-03-05 | 2013-03-05 | |
| US61/772,979 | 2013-03-05 | ||
| PCT/US2013/072691 WO2014085826A2 (en) | 2012-11-30 | 2013-12-02 | Method for evaluation of presence of or risk of colon tumors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016507723A JP2016507723A (ja) | 2016-03-10 |
| JP2016507723A5 true JP2016507723A5 (cg-RX-API-DMAC7.html) | 2017-01-19 |
Family
ID=50828610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015545504A Pending JP2016507723A (ja) | 2012-11-30 | 2013-12-02 | 結腸腫瘍の存在またはリスクの評価方法 |
Country Status (11)
Families Citing this family (63)
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| US9141756B1 (en) | 2010-07-20 | 2015-09-22 | University Of Southern California | Multi-scale complex systems transdisciplinary analysis of response to therapy |
| CA2863819C (en) | 2012-02-09 | 2021-11-23 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections and methods of use thereof |
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| EP3167293B1 (en) * | 2014-07-11 | 2020-03-18 | Expression Pathology, Inc. | Srm/mrm assay for the gtpase kras protein (kras) |
| EP3699930B1 (en) | 2014-08-14 | 2024-02-07 | MeMed Diagnostics Ltd. | Computational analysis of biological data using manifold and a hyperplane |
| WO2016037134A1 (en) * | 2014-09-05 | 2016-03-10 | Nantomics, Llc | Systems and methods for determination of provenance |
| JP2017538938A (ja) * | 2014-12-11 | 2017-12-28 | ウイスコンシン・アルムニ・リサーチ・ファンデーション | 大腸癌の検出及び処置方法 |
| CN107209184B (zh) | 2014-12-11 | 2020-04-24 | 米密德诊断学有限公司 | 用于诊断多种感染的标记组合及其使用方法 |
| CN105807062A (zh) * | 2014-12-28 | 2016-07-27 | 复旦大学 | 人结肠癌蛋白Spondin-2在制备结肠癌诊断制剂中的应用 |
| CN105385752A (zh) * | 2015-03-23 | 2016-03-09 | 复旦大学 | 一种人结肠癌蛋白质标志物Spondin-2的检测方法及其检测试剂盒 |
| CA2982169A1 (en) | 2015-04-10 | 2016-10-13 | Applied Proteomics, Inc. | Protein biomarker panels for detecting colorectal cancer and advanced adenoma |
| EP3316875B1 (en) * | 2015-07-01 | 2021-11-17 | Duke University | Methods to diagnose acute respiratory infections |
| WO2017078787A1 (en) * | 2015-11-05 | 2017-05-11 | Vanderbilt University | Protein quantitation in multicellular tissue specimens |
| WO2017149548A1 (en) | 2016-03-03 | 2017-09-08 | Memed Diagnostics Ltd. | Rna determinants for distinguishing between bacterial and viral infections |
| EP3443497A1 (en) * | 2016-04-11 | 2019-02-20 | DiscernDx, Inc. | Mass spectrometric data analysis workflow |
| JP6754116B2 (ja) * | 2016-04-26 | 2020-09-09 | 学校法人近畿大学 | 大腸癌マーカー |
| CN107345236A (zh) * | 2016-05-04 | 2017-11-14 | 北京美泽福临科技发展有限公司 | 一种amy2b信使rna的特异性扩增引物和肝癌辅助诊断试剂盒 |
| CA3025004A1 (en) * | 2016-06-10 | 2017-12-14 | Wisconsin Alumni Research Foundation | Methods for detection, staging, and surveillance of colorectal adenomas and carcinomas |
| EP4141448A1 (en) | 2016-07-10 | 2023-03-01 | MeMed Diagnostics Ltd. | Protein signatures for distinguishing between bacterial and viral infections |
| WO2018011796A1 (en) | 2016-07-10 | 2018-01-18 | Memed Diagnostics Ltd. | Early diagnosis of infections |
| CN106202984B (zh) * | 2016-08-26 | 2018-09-04 | 赵毅 | 一种基于多层复杂网络对肿瘤miRNA标志物的筛选方法 |
| WO2018060998A1 (en) | 2016-09-29 | 2018-04-05 | Memed Diagnostics Ltd. | Methods of prognosis and treatment |
| EP3519834A4 (en) * | 2016-09-29 | 2020-06-17 | MeMed Diagnostics Ltd. | RISK ASSESSMENT AND DISEASE CLASSIFICATION METHODS |
| US20180100858A1 (en) * | 2016-10-07 | 2018-04-12 | Applied Proteomics, Inc. | Protein biomarker panels for detecting colorectal cancer and advanced adenoma |
| CN110214271B (zh) * | 2017-01-19 | 2022-11-15 | 株式会社岛津制作所 | 分析数据解析方法以及分析数据解析装置 |
| US11204355B2 (en) | 2017-02-20 | 2021-12-21 | Vanderbilt University | Immune checkpoint molecular fitness profiling by mass spectrometry |
| CN106919801B (zh) * | 2017-03-08 | 2023-07-18 | 杭州大伽信息科技有限公司 | 一种免疫组织化学染色辅助分析系统及使用方法 |
| CN106908608B (zh) * | 2017-04-17 | 2018-10-02 | 首都医科大学附属北京胸科医院 | 辅助诊断重症继发性肺结核的蛋白标志物 |
| US20180330059A1 (en) * | 2017-05-09 | 2018-11-15 | James Stewart Bates | Patient treatment systems and methods |
| US10455457B2 (en) | 2017-05-24 | 2019-10-22 | Qualcomm Incorporated | NR-SS unified operation mode in coordinated and uncoordinated bands |
| US11164679B2 (en) | 2017-06-20 | 2021-11-02 | Advinow, Inc. | Systems and methods for intelligent patient interface exam station |
| US20200124604A1 (en) * | 2017-06-30 | 2020-04-23 | National Institutes Of Biomedical Innovation, Health And Nutrition | Biomarker for detecting colorectal cancer |
| CN111164700B (zh) * | 2017-07-14 | 2024-10-29 | 余因子基因组学公司 | 使用下一代测序的免疫-肿瘤学应用 |
| CN109406785A (zh) * | 2017-08-18 | 2019-03-01 | 山东泽济生物科技有限公司 | 肿瘤血液标志物及其应用 |
| EP3721232A1 (en) * | 2017-12-05 | 2020-10-14 | DiscernDx, Inc. | Robust panels of colorectal cancer biomarkers |
| EP3732489B1 (en) * | 2017-12-29 | 2025-10-22 | Abbott Laboratories | Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury |
| ES2917629T3 (es) * | 2018-01-22 | 2022-07-11 | Liquid Biopsy Res Llc | Métodos para la detección del cáncer de colon y monitorización del tratamiento |
| US11348688B2 (en) | 2018-03-06 | 2022-05-31 | Advinow, Inc. | Systems and methods for audio medical instrument patient measurements |
| EP3776381A4 (en) | 2018-04-13 | 2022-01-05 | Freenome Holdings, Inc. | IMPLEMENTATION OF MACHINE LEARNING FOR MULTI-ANALYTE TESTS OF BIOLOGICAL SAMPLES |
| EP3818376A1 (en) * | 2018-07-05 | 2021-05-12 | EDP Biotech Corporation | Kits and methods for detecting markers |
| EA202190355A1 (ru) | 2018-08-08 | 2021-05-25 | Ридженерон Фармасьютикалз, Инк. | Применение жх-мс/мс для количественного определения белковых биомаркеров |
| EP3623813A1 (en) * | 2018-09-17 | 2020-03-18 | Institut d'Investigació Sanitària Pere Virgili | Methods for the prognosis of hiv-infected subjects |
| JP7539399B2 (ja) * | 2019-03-06 | 2024-08-23 | ディアデム エス．アール．エル． | アルツハイマー病の診断と予後判定におけるマーカーとしてのｐ５３ペプチド |
| WO2021097302A1 (en) * | 2019-11-13 | 2021-05-20 | University Of South Florida | Systems and methods of deep learning for colorectal polyp screening |
| CN110951707B (zh) * | 2019-12-31 | 2022-11-11 | 南京医科大学 | 丙酮酸激酶m2突变体及其在心血管疾病中的应用 |
| CN115616230A (zh) * | 2020-03-18 | 2023-01-17 | 龙海市第一医院 | 用于肝癌早期诊断的检测岩藻糖基化载脂蛋白h的elisa试剂盒 |
| WO2022006628A1 (en) * | 2020-07-08 | 2022-01-13 | Southern Adelaide Local Health Network Inc. | Computer-implemented method and system for identifying measurable features for use in a predictive model |
| CN112194719A (zh) * | 2020-09-01 | 2021-01-08 | 中日友好医院(中日友好临床医学研究所) | Crt抗原和mage-a1抗原的制备及其应用 |
| CN112034182A (zh) * | 2020-09-01 | 2020-12-04 | 复旦大学附属中山医院 | 一种结肠癌转移预测方法和系统 |
| CN112266961B (zh) * | 2020-10-29 | 2023-05-12 | 中山大学附属第六医院 | Tsg-6基因在预测结直肠癌转移及预后方面的应用 |
| CN112710856B (zh) * | 2020-12-16 | 2022-12-02 | 江西省肿瘤医院(江西省癌症中心) | 检测血清igf1蛋白的制剂在制备结直肠癌疗效监测试剂中的应用 |
| CN113447658B (zh) * | 2021-07-01 | 2022-04-19 | 浙江大学 | 一种检测抗过氧化物还原酶-1-IgG抗体的试剂盒 |
| CN113956327B (zh) * | 2021-10-11 | 2024-01-30 | 中山大学肿瘤防治中心 | 靶向人apc蛋白的多肽及其在制备药物中的应用 |
| EP4497005A1 (en) * | 2022-03-23 | 2025-01-29 | Serum Detect, Inc. | Biomarker signatures indicative of early stages of cancer |
| CN114445406B (zh) * | 2022-04-07 | 2022-08-09 | 武汉大学 | 肠镜图像分析方法、装置和医学图像处理设备 |
| TWI796228B (zh) | 2022-05-25 | 2023-03-11 | 臺中榮民總醫院 | 急性腎損傷預測系統及其方法 |
| CN114668836B (zh) * | 2022-05-27 | 2022-08-19 | 暨南大学 | Pdia6在制备治疗脊髓损伤和修复的药物中的应用 |
| CN114958794B (zh) * | 2022-06-14 | 2023-06-02 | 南京工业大学 | 一种苯乙醇胺-N-甲基转移酶hPNMT54及其克隆表达与应用 |
| CN116593431B (zh) * | 2023-04-09 | 2025-11-07 | 湖南科技大学三亚研究院 | 一种基于亲和传感器法的米酵菌酸毒素便携式检测装置及检测方法 |
| WO2024232926A1 (en) * | 2023-05-08 | 2024-11-14 | Venn Biosciences Corporation | Diagnosis of colorectal cancer using targeted quantification of peptides |
| WO2025058445A1 (ko) * | 2023-09-15 | 2025-03-20 | 연세대학교 산학협력단 | 대장암에 대한 정보 제공 방법 |
| CN118067993B (zh) * | 2024-04-17 | 2024-07-05 | 弗雷米德生物医药技术（天津）有限公司 | 一种用于肠息肉检测的联检试剂盒及其制备方法、检测方法和应用 |
| CN118496322A (zh) * | 2024-05-09 | 2024-08-16 | 昆明医科大学 | 一种靶向降解β-catenin的多肽型抑制剂及其应用 |
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| US5800347A (en) * | 1995-11-03 | 1998-09-01 | The General Hospital Corporation | ROC method for early detection of disease |
| NO954667D0 (no) * | 1995-11-17 | 1995-11-17 | Dagfinn Oegreid | Fremgangsmåte til deteksjon av Ki-ras mutasjoner |
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-
2013
- 2013-12-02 CN CN201380071930.XA patent/CN104969071B/zh not_active Expired - Fee Related
- 2013-12-02 WO PCT/US2013/072691 patent/WO2014085826A2/en not_active Ceased
- 2013-12-02 MX MX2015006757A patent/MX2015006757A/es unknown
- 2013-12-02 JP JP2015545504A patent/JP2016507723A/ja active Pending
- 2013-12-02 US US14/094,594 patent/US20140234854A1/en not_active Abandoned
- 2013-12-02 SG SG11201504241QA patent/SG11201504241QA/en unknown
- 2013-12-02 AU AU2013351947A patent/AU2013351947A1/en not_active Abandoned
- 2013-12-02 KR KR1020157017551A patent/KR20150090240A/ko not_active Withdrawn
- 2013-12-02 CA CA2893158A patent/CA2893158A1/en not_active Abandoned
- 2013-12-02 EP EP13858410.7A patent/EP2926138A4/en not_active Ceased
- 2013-12-02 BR BR112015012616A patent/BR112015012616A2/pt not_active IP Right Cessation
- 2013-12-02 CN CN201910577840.7A patent/CN110596385A/zh active Pending
-
2014
- 2014-10-28 US US14/526,265 patent/US20150111230A1/en not_active Abandoned
- 2014-10-28 US US14/526,221 patent/US20150111220A1/en not_active Abandoned
- 2014-10-28 US US14/526,282 patent/US20150111221A1/en not_active Abandoned
- 2014-10-28 US US14/526,181 patent/US20150111223A1/en not_active Abandoned
-
2017
- 2017-06-14 US US15/622,340 patent/US20170285033A1/en not_active Abandoned
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