JP2016506366A5 - - Google Patents

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Publication number
JP2016506366A5
JP2016506366A5 JP2015541857A JP2015541857A JP2016506366A5 JP 2016506366 A5 JP2016506366 A5 JP 2016506366A5 JP 2015541857 A JP2015541857 A JP 2015541857A JP 2015541857 A JP2015541857 A JP 2015541857A JP 2016506366 A5 JP2016506366 A5 JP 2016506366A5
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JP
Japan
Prior art keywords
insulin
wild
prior
patent document
documents cited
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JP2015541857A
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English (en)
Japanese (ja)
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JP2016506366A (ja
JP6584953B2 (ja
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Priority claimed from PCT/US2013/068585 external-priority patent/WO2014071405A2/en
Publication of JP2016506366A publication Critical patent/JP2016506366A/ja
Publication of JP2016506366A5 publication Critical patent/JP2016506366A5/ja
Application granted granted Critical
Publication of JP6584953B2 publication Critical patent/JP6584953B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015541857A 2012-11-05 2013-11-05 長時間作用型単鎖インスリン類似体 Expired - Fee Related JP6584953B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261722350P 2012-11-05 2012-11-05
US61/722,350 2012-11-05
PCT/US2013/068585 WO2014071405A2 (en) 2012-11-05 2013-11-05 Long-acting single-chain insulin analogues

Publications (3)

Publication Number Publication Date
JP2016506366A JP2016506366A (ja) 2016-03-03
JP2016506366A5 true JP2016506366A5 (enExample) 2016-12-15
JP6584953B2 JP6584953B2 (ja) 2019-10-02

Family

ID=50628271

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015541857A Expired - Fee Related JP6584953B2 (ja) 2012-11-05 2013-11-05 長時間作用型単鎖インスリン類似体

Country Status (15)

Country Link
US (2) US9499600B2 (enExample)
EP (1) EP2914620B1 (enExample)
JP (1) JP6584953B2 (enExample)
KR (1) KR102163936B1 (enExample)
CN (2) CN105008395B (enExample)
AU (1) AU2013337250B2 (enExample)
BR (1) BR112015010194B1 (enExample)
CA (1) CA2890719C (enExample)
EA (1) EA201590882A1 (enExample)
ES (1) ES2694418T3 (enExample)
IL (1) IL238651B (enExample)
MX (1) MX2015005662A (enExample)
PH (1) PH12015500989A1 (enExample)
SG (1) SG11201503522RA (enExample)
WO (1) WO2014071405A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014015078A1 (en) * 2012-07-17 2014-01-23 Michael Weiss O-linked carbohydrate-modified insulin analogues
US9624287B2 (en) 2012-07-17 2017-04-18 Case Western Reserve University O-linked carbohydrate-modified insulin analogues
KR102351111B1 (ko) 2014-01-13 2022-01-14 써멀린 다이어비티즈, 엘엘씨 초속효성 인슐린 제형 및 약제학적 전달 시스템
CZ308383B6 (cs) * 2014-06-30 2020-07-15 Ústav Organické Chemie A Biochemie Akademie Věd Čr, V.V.I. Derivát inzulinu s cyklickou strukturou v C-konci B-řetězce
CA2961037A1 (en) * 2014-10-06 2016-04-14 Case Western Reserve University Biphasic single-chain insulin analogues
AR105616A1 (es) 2015-05-07 2017-10-25 Lilly Co Eli Proteínas de fusión
EP3393498A4 (en) * 2015-12-23 2019-08-07 Case Western Reserve University SECULATION OF ULTRASTABILEN INSULIN ANALOGUE WITH POLYMER MELTS
JP2022507627A (ja) * 2018-11-19 2022-01-18 ケース ウェスタン リザーブ ユニバーシティ ポリ－アラニンｃ－ドメインのサブセグメントを有する単鎖インスリンアナログ
WO2020120477A1 (en) 2018-12-11 2020-06-18 Sanofi Insulin analogs having reduced insulin receptor binding affinity
TW202434620A (zh) 2019-07-31 2024-09-01 美商美國禮來大藥廠 鬆弛素(relaxin)類似物及其使用方法
AU2020399194A1 (en) * 2019-12-10 2022-07-28 Sanofi A method of forming a conjugate of a sulfonamide and a polypeptide
CN118201954A (zh) 2021-09-20 2024-06-14 克云生物科技股份公司 精氨酸酶-胰岛素融合蛋白

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE270306T1 (de) * 2000-10-02 2004-07-15 Univ Yonsei Seoul Einkettige insulinanaloge
KR100449454B1 (ko) 2000-10-02 2004-09-21 이현철 단일사슬 인슐린 유도체의 유전자를 포함하는 당뇨병치료용 벡터
US20060217290A1 (en) * 2003-04-29 2006-09-28 Kohn Wayne D Insulin analogs having protracted time action
KR100508616B1 (ko) * 2003-06-20 2005-08-17 신항철 염기성 아미노산 첨가를 통한 활성이 증가된 단일사슬 인슐린 아날로그
JP5697831B2 (ja) * 2003-12-03 2015-04-08 ノヴォ ノルディスク アー／エス 単鎖インシュリン
WO2008043033A2 (en) * 2006-10-04 2008-04-10 Case Western Reserve University Fibrillation-resistant insulin and insulin analogues
WO2009132129A2 (en) * 2008-04-22 2009-10-29 Case Western Reserve University Isoform-specific insulin analogues
KR101853606B1 (ko) * 2009-07-06 2018-05-03 사노피-아벤티스 도이칠란트 게엠베하 메티오닌을 함유하는 수성 인슐린 제제
TW201105346A (en) * 2009-07-06 2011-02-16 Sanofi Aventis Deutschland Heat-stable and vibration-stable insulin preparations
US8399407B2 (en) 2009-09-17 2013-03-19 Case Western Reserve University Non-standard insulin analogues
KR20150021011A (ko) * 2011-10-27 2015-02-27 케이스 웨스턴 리저브 유니버시티 초고도 농축된, 속효성 인슐린 유사체 제형
JP2015507916A (ja) * 2012-01-20 2015-03-16 ケース ウェスタン リザーブ ユニバーシティＣａｓｅ Ｗｅｓｔｅｒｎｒｅｓｅｒｖｅ Ｕｎｉｖｅｒｓｉｔｙ グルタミン酸安定化インスリン類似体
CN108383902A (zh) * 2012-09-26 2018-08-10 印第安纳大学研究及科技有限公司 胰岛素类似物二聚体

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