JP2016503800A5 - - Google Patents
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- JP2016503800A5 JP2016503800A5 JP2015549743A JP2015549743A JP2016503800A5 JP 2016503800 A5 JP2016503800 A5 JP 2016503800A5 JP 2015549743 A JP2015549743 A JP 2015549743A JP 2015549743 A JP2015549743 A JP 2015549743A JP 2016503800 A5 JP2016503800 A5 JP 2016503800A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- items
- compound according
- pharmaceutical composition
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261745452P | 2012-12-21 | 2012-12-21 | |
| US61/745,452 | 2012-12-21 | ||
| US13/830,346 US9233974B2 (en) | 2012-12-21 | 2013-03-14 | Antiviral compounds |
| US13/830,346 | 2013-03-14 | ||
| PCT/US2013/076734 WO2014100500A1 (en) | 2012-12-21 | 2013-12-19 | Antiviral compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016503800A JP2016503800A (ja) | 2016-02-08 |
| JP2016503800A5 true JP2016503800A5 (https=) | 2017-01-12 |
| JP6333849B2 JP6333849B2 (ja) | 2018-05-30 |
Family
ID=50974893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015549743A Active JP6333849B2 (ja) | 2012-12-21 | 2013-12-19 | 抗ウイルス化合物 |
Country Status (28)
| Country | Link |
|---|---|
| US (5) | US9233974B2 (https=) |
| EP (3) | EP3404030A1 (https=) |
| JP (1) | JP6333849B2 (https=) |
| KR (2) | KR102164390B1 (https=) |
| CN (2) | CN107011350A (https=) |
| AP (1) | AP2015008511A0 (https=) |
| AR (1) | AR094262A1 (https=) |
| AU (1) | AU2013361195B2 (https=) |
| BR (1) | BR112015014333A8 (https=) |
| CA (1) | CA2893963C (https=) |
| CL (1) | CL2015001702A1 (https=) |
| CR (1) | CR20150370A (https=) |
| EA (2) | EA027828B1 (https=) |
| ES (1) | ES2626392T3 (https=) |
| HK (2) | HK1214594A1 (https=) |
| IL (1) | IL239496A0 (https=) |
| MA (1) | MA38261A1 (https=) |
| MD (1) | MD20150062A2 (https=) |
| MX (1) | MX2015007888A (https=) |
| PE (1) | PE20151423A1 (https=) |
| PH (1) | PH12015501354A1 (https=) |
| PL (1) | PL2935279T3 (https=) |
| PT (1) | PT2935279T (https=) |
| SG (1) | SG11201504746PA (https=) |
| SI (1) | SI2935279T1 (https=) |
| TW (2) | TW201835087A (https=) |
| UY (1) | UY35241A (https=) |
| WO (1) | WO2014100500A1 (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ710567A (en) | 2010-11-17 | 2017-01-27 | Gilead Sciences Inc | Antiviral compounds |
| CN105837584B (zh) | 2011-11-16 | 2018-07-13 | 吉利德制药有限责任公司 | 作为抗病毒化合物的缩合的咪唑基咪唑 |
| US20130309196A1 (en) * | 2012-05-16 | 2013-11-21 | Gilead Sciences, Inc. | Antiviral compounds |
| BR112015014457A2 (pt) | 2012-12-21 | 2017-11-21 | Alios Biopharma Inc | composto ou sal farmaceuticamente aceitável do mesmo e composição farmacêutica e respectivos usos e processos para melhorar ou tratar infecção de hcv, para inibir a atividade da ns5b polimerase do vírus da hepatite c e a replicação de vírus da hepatite c |
| US9398640B2 (en) | 2012-12-21 | 2016-07-19 | Halliburton Energy Services, Inc. | Digital multi-use thermo-cup |
| UA111305C2 (uk) | 2012-12-21 | 2016-04-11 | Пфайзер Інк. | Конденсовані лактами арилу та гетероарилу |
| US9604982B2 (en) | 2013-03-14 | 2017-03-28 | Janssen Pharmaceutica Nv | P2X7 modulators |
| TWI644671B (zh) | 2013-03-14 | 2018-12-21 | 比利時商健生藥品公司 | Ｐ２ｘ７調節劑 |
| US9040534B2 (en) | 2013-03-14 | 2015-05-26 | Janssen Pharmaceutica Nv | [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators |
| JO3509B1 (ar) | 2013-03-14 | 2020-07-05 | Janssen Pharmaceutica Nv | معدلات p2x7 |
| ES2845473T3 (es) | 2013-03-14 | 2021-07-26 | Boehringer Ingelheim Int | (Bencil-ciano-metil)-amidas sustituidas de ácido 2-aza-biciclo[2.2.1]heptano-3-carboxílico inhibidores de la catepsina- C |
| US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
| US9775831B2 (en) | 2013-07-17 | 2017-10-03 | Bristol-Myers Squibb Company | Combinations comprising biphenyl derivatives for use in the treatment of HCV |
| PT3038601T (pt) | 2013-08-27 | 2020-06-30 | Gilead Pharmasset Llc | Formulação combinada de dois compostos antivirais |
| TWI721947B (zh) | 2014-06-11 | 2021-03-21 | 美商基利法瑪席特有限責任公司 | 抗病毒化合物的固態形式 |
| TN2016000529A1 (en) | 2014-06-17 | 2018-04-04 | Pfizer | Substituted dihydroisoquinolinone compounds |
| AU2015315693B2 (en) | 2014-09-12 | 2020-01-16 | Janssen Pharmaceutica Nv | P2X7 modulating n-acyl-triazolopyrazines |
| WO2016039977A1 (en) | 2014-09-12 | 2016-03-17 | Janssen Pharmaceutica Nv | P2x7 modulators |
| EP3511331A1 (en) | 2014-09-12 | 2019-07-17 | Boehringer Ingelheim International GmbH | Spirocyclic inhibitors of cathepsin c |
| JP7381190B2 (ja) | 2014-12-26 | 2023-11-15 | エモリー・ユニバーシテイ | Ｎ４－ヒドロキシシチジン及び誘導体並びにそれに関連する抗ウイルス用途 |
| CN110372559A (zh) * | 2014-12-29 | 2019-10-25 | 重庆博腾制药科技股份有限公司 | 一种(4S)-N-Boc-4--甲氧基甲基-L-脯氨酸的合成方法 |
| WO2017023631A1 (en) | 2015-08-06 | 2017-02-09 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| CN105732765B (zh) * | 2016-02-01 | 2019-07-26 | 杭州科巢生物科技有限公司 | 丙肝药物维帕他韦的新合成方法 |
| CN106916134B (zh) * | 2016-04-14 | 2020-04-17 | 苏州楚凯药业有限公司 | 一种10,11-二氢-5H-苯并[d]萘并[2,3-b]吡喃酮衍生物的制备方法 |
| CN109641874A (zh) | 2016-05-10 | 2019-04-16 | C4医药公司 | 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体 |
| ES2990061T3 (es) | 2016-05-10 | 2024-11-28 | C4 Therapeutics Inc | Degronímeros espirocíclicos para la degradación de proteínas diana |
| CN109790143A (zh) | 2016-05-10 | 2019-05-21 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
| EP3454856B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| EA201892375A1 (ru) | 2016-05-27 | 2019-08-30 | Джилид Сайэнс, Инк. | Способы лечения инфекций, вызываемых вирусом гепатита b |
| CN106831737B (zh) * | 2017-02-27 | 2020-03-17 | 上海众强药业有限公司 | 维帕他韦及其衍生物的制备 |
| CN110769822A (zh) | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| AU2018335411B2 (en) * | 2017-09-21 | 2024-06-27 | Riboscience Llc | 4'-fluoro-2'-methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication |
| PT3706762T (pt) | 2017-12-07 | 2024-12-05 | Univ Emory | N4-hidroxicitidina e derivados e utilizações antivirais relacionadas com os mesmos |
| KR20210069079A (ko) | 2018-09-28 | 2021-06-10 | 얀센 파마슈티카 엔.브이. | 모노아실글리세롤 리파아제 조절제 |
| MY205440A (en) | 2018-09-28 | 2024-10-21 | Janssen Pharmaceutica Nv | Monoacylglycerol lipase modulators |
| JP7697934B2 (ja) | 2019-09-30 | 2025-06-24 | ヤンセン ファーマシューティカ エヌ．ベー． | 放射線標識されたｍｇｌ ｐｅｔリガンド |
| BR112022019077A2 (pt) | 2020-03-26 | 2022-12-27 | Janssen Pharmaceutica Nv | Moduladores da monoacilglicerol lipase |
| US12037340B2 (en) | 2021-05-21 | 2024-07-16 | Gilead Sciences, Inc. | Pentacyclic derivatives as Zika virus inhibitors |
| US12497408B2 (en) | 2021-05-21 | 2025-12-16 | Gilead Sciences, Inc. | Tetracyclic compounds and methods for the treatment of Zika virus infection |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816570A (en) | 1982-11-30 | 1989-03-28 | The Board Of Regents Of The University Of Texas System | Biologically reversible phosphate and phosphonate protective groups |
| US4968788A (en) | 1986-04-04 | 1990-11-06 | Board Of Regents, The University Of Texas System | Biologically reversible phosphate and phosphonate protective gruops |
| EP0481214B1 (en) | 1990-09-14 | 1998-06-24 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Prodrugs of phosphonates |
| US5543523A (en) | 1994-11-15 | 1996-08-06 | Regents Of The University Of Minnesota | Method and intermediates for the synthesis of korupensamines |
| RS51974B (sr) | 2004-07-16 | 2012-02-29 | Gilead Sciences Inc. | Antivirusna jedinjenja |
| US7741347B2 (en) * | 2007-05-17 | 2010-06-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US20120040977A1 (en) * | 2009-02-23 | 2012-02-16 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| NZ710567A (en) | 2010-11-17 | 2017-01-27 | Gilead Sciences Inc | Antiviral compounds |
| US8552047B2 (en) * | 2011-02-07 | 2013-10-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| US20130309196A1 (en) * | 2012-05-16 | 2013-11-21 | Gilead Sciences, Inc. | Antiviral compounds |
| AR091279A1 (es) | 2012-06-08 | 2015-01-21 | Gilead Sciences Inc | Inhibidores macrociclicos de virus flaviviridae |
-
2013
- 2013-03-14 US US13/830,346 patent/US9233974B2/en active Active
- 2013-12-19 ES ES13819144.0T patent/ES2626392T3/es active Active
- 2013-12-19 MX MX2015007888A patent/MX2015007888A/es unknown
- 2013-12-19 SG SG11201504746PA patent/SG11201504746PA/en unknown
- 2013-12-19 CN CN201710186037.1A patent/CN107011350A/zh active Pending
- 2013-12-19 MD MDA20150062A patent/MD20150062A2/ro not_active Application Discontinuation
- 2013-12-19 EP EP18169933.1A patent/EP3404030A1/en not_active Withdrawn
- 2013-12-19 JP JP2015549743A patent/JP6333849B2/ja active Active
- 2013-12-19 EA EA201590868A patent/EA027828B1/ru not_active IP Right Cessation
- 2013-12-19 MA MA38261A patent/MA38261A1/fr unknown
- 2013-12-19 PT PT138191440T patent/PT2935279T/pt unknown
- 2013-12-19 SI SI201330634A patent/SI2935279T1/sl unknown
- 2013-12-19 KR KR1020157018764A patent/KR102164390B1/ko active Active
- 2013-12-19 CN CN201380066203.4A patent/CN104918943B/zh active Active
- 2013-12-19 AP AP2015008511A patent/AP2015008511A0/xx unknown
- 2013-12-19 WO PCT/US2013/076734 patent/WO2014100500A1/en not_active Ceased
- 2013-12-19 PL PL13819144T patent/PL2935279T3/pl unknown
- 2013-12-19 AU AU2013361195A patent/AU2013361195B2/en active Active
- 2013-12-19 CA CA2893963A patent/CA2893963C/en active Active
- 2013-12-19 PE PE2015001025A patent/PE20151423A1/es not_active Application Discontinuation
- 2013-12-19 BR BR112015014333A patent/BR112015014333A8/pt not_active Application Discontinuation
- 2013-12-19 KR KR1020207028460A patent/KR20200118903A/ko not_active Ceased
- 2013-12-19 HK HK16102505.6A patent/HK1214594A1/zh unknown
- 2013-12-19 EA EA201790781A patent/EA201790781A3/ru unknown
- 2013-12-19 EP EP17160687.4A patent/EP3239152A1/en not_active Withdrawn
- 2013-12-19 EP EP13819144.0A patent/EP2935279B1/en active Active
- 2013-12-20 AR ARP130105004A patent/AR094262A1/es unknown
- 2013-12-20 TW TW106146566A patent/TW201835087A/zh unknown
- 2013-12-20 UY UY0001035241A patent/UY35241A/es not_active Application Discontinuation
- 2013-12-20 TW TW102147531A patent/TWI613202B/zh active
-
2015
- 2015-06-15 PH PH12015501354A patent/PH12015501354A1/en unknown
- 2015-06-17 CL CL2015001702A patent/CL2015001702A1/es unknown
- 2015-06-18 IL IL239496A patent/IL239496A0/en unknown
- 2015-07-10 CR CR20150370A patent/CR20150370A/es unknown
- 2015-12-03 US US14/957,988 patent/US20160083395A1/en not_active Abandoned
-
2016
- 2016-08-24 US US15/246,074 patent/US20160362416A1/en not_active Abandoned
-
2017
- 2017-08-16 US US15/679,014 patent/US20170369502A1/en not_active Abandoned
-
2018
- 2018-01-22 US US15/876,909 patent/US20180244684A1/en not_active Abandoned
- 2018-04-10 HK HK18104658.5A patent/HK1245263A1/en unknown
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