JP2016128507A5 - - Google Patents
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- Publication number
- JP2016128507A5 JP2016128507A5 JP2016058155A JP2016058155A JP2016128507A5 JP 2016128507 A5 JP2016128507 A5 JP 2016128507A5 JP 2016058155 A JP2016058155 A JP 2016058155A JP 2016058155 A JP2016058155 A JP 2016058155A JP 2016128507 A5 JP2016128507 A5 JP 2016128507A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- virus
- leukemia
- crystal
- hepatitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910259339.2 | 2009-12-18 | ||
| CN2009102593392A CN102101886A (zh) | 2009-12-18 | 2009-12-18 | 构象改变的重组干扰素晶体、其三维结构及应用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543445A Division JP2013514279A (ja) | 2009-12-18 | 2010-12-16 | 変更された空間構成を有する結晶性組換型インターフェロン、その三次元構造、およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016128507A JP2016128507A (ja) | 2016-07-14 |
| JP2016128507A5 true JP2016128507A5 (enExample) | 2016-08-25 |
Family
ID=44154975
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543445A Pending JP2013514279A (ja) | 2009-12-18 | 2010-12-16 | 変更された空間構成を有する結晶性組換型インターフェロン、その三次元構造、およびその使用 |
| JP2016058155A Pending JP2016128507A (ja) | 2009-12-18 | 2016-03-23 | 変更された空間構成を有する結晶性組換型インターフェロン、その三次元構造、およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543445A Pending JP2013514279A (ja) | 2009-12-18 | 2010-12-16 | 変更された空間構成を有する結晶性組換型インターフェロン、その三次元構造、およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8846025B2 (enExample) |
| EP (1) | EP2514761B1 (enExample) |
| JP (2) | JP2013514279A (enExample) |
| KR (1) | KR20120108985A (enExample) |
| CN (2) | CN102101886A (enExample) |
| AU (1) | AU2010333574B2 (enExample) |
| CA (1) | CA2784624C (enExample) |
| ES (1) | ES2631028T3 (enExample) |
| MY (1) | MY169650A (enExample) |
| SG (1) | SG181785A1 (enExample) |
| WO (1) | WO2011072487A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102101886A (zh) | 2009-12-18 | 2011-06-22 | 四川辉阳生命工程股份有限公司 | 构象改变的重组干扰素晶体、其三维结构及应用 |
| TWI726291B (zh) | 2013-01-07 | 2021-05-01 | 英屬維爾京群島商遠東超級實驗室有限公司 | 通過干擾素的經皮和/或經粘膜給藥治療骨癌、皮膚癌、皮下癌、粘膜癌和/或粘膜下癌的方法和組合物 |
| US9830422B1 (en) * | 2013-07-22 | 2017-11-28 | The Curators Of The University Of Missouri | In silico biological and pharmaceutical modeling |
| WO2015103643A2 (en) | 2014-01-06 | 2015-07-09 | The General Hospital Corporation | Integrin antagonists |
| WO2016180335A1 (en) * | 2015-05-12 | 2016-11-17 | Superlab Far East Limited | Methods of determining interferon having direct inhibitory effects on tumors and uses thereof |
| WO2019134318A1 (zh) * | 2018-05-09 | 2019-07-11 | 深圳晶泰科技有限公司 | 药物晶体结构全景分析系统及其全景分析方法 |
| CN111508568B (zh) * | 2020-04-20 | 2023-08-29 | 腾讯科技（深圳）有限公司 | 分子生成方法、装置及计算机可读存储介质和终端设备 |
| CN111658779A (zh) * | 2020-06-22 | 2020-09-15 | 四川大学华西医院 | 治疗新型冠状病毒肺炎的联合用药物 |
| CN113223631B (zh) * | 2021-05-06 | 2024-05-24 | 吉林大学 | 一种晶体结构解析方法及系统 |
| CN119670712B (zh) * | 2024-11-28 | 2025-10-03 | 中国人民解放军总医院 | 基于bert模型的临床知情同意书智能推荐装置 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4672108A (en) | 1981-12-07 | 1987-06-09 | Hoffmann-La Roche Inc. | Crystalline human leukocyte interferon |
| US6936694B1 (en) | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
| US5372808A (en) | 1990-10-17 | 1994-12-13 | Amgen Inc. | Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect |
| US5441734A (en) | 1993-02-25 | 1995-08-15 | Schering Corporation | Metal-interferon-alpha crystals |
| TW426523B (en) | 1995-04-06 | 2001-03-21 | Hoffmann La Roche | Interferon solution |
| US5480640A (en) | 1995-05-02 | 1996-01-02 | Schering Corporation | Alpha interferon for treating prostate cancer |
| US5972331A (en) | 1995-12-22 | 1999-10-26 | Schering Corporation | Crystalline interferon alpha for pulmonary delivery and method for producing the same |
| WO1999045389A2 (en) | 1998-03-06 | 1999-09-10 | Abbott Lab | Ligand screening and design by x-ray crystallography |
| CN1062565C (zh) | 1998-06-29 | 2001-02-28 | 深圳九先生物工程有限公司 | 重组人α型复合干扰素及其制备方法和用途 |
| US6833256B1 (en) * | 1999-06-22 | 2004-12-21 | University Of Maryland | Interferon tau mutants and methods for making them |
| EP2292652A2 (en) | 2000-11-03 | 2011-03-09 | Pestka Biomedical Laboratories, Inc. | Interferons uses and compositions related thereto |
| AU2002223350A1 (en) * | 2000-12-01 | 2002-06-11 | Eleanor N. Fish | Cytokine receptor binding peptides |
| CN1245215C (zh) * | 2001-02-28 | 2006-03-15 | 四川省生物工程研究中心 | 重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂 |
| US20060035327A1 (en) | 2001-02-28 | 2006-02-16 | Guangwen Wei | Recombinant super-compound interferon and uses thereof |
| FR2823764B1 (fr) * | 2001-04-24 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides et polypeptides du gene ifn alpha-17 |
| CN101001644B (zh) * | 2003-08-28 | 2011-09-21 | 辉阳科技美国公司 | 空间构象改变的干扰素及其应用 |
| AU2004269390A1 (en) * | 2003-08-28 | 2005-03-10 | Huiyangtech (Usa), Inc. | Uses of spatial configuration to modulate protein function |
| US7585647B2 (en) * | 2003-08-28 | 2009-09-08 | Guangwen Wei | Nucleic acid encoding recombinant interferon |
| KR101431172B1 (ko) | 2003-08-28 | 2014-08-19 | 수퍼랩 파 이스트 리미티드 | 변경된 공간 구조를 갖는 인터페론의 용도 |
| WO2005067963A1 (en) | 2003-12-23 | 2005-07-28 | Intermune, Inc. | Use of polyethylene glycol-modified interferon-alpha in therapeutic dosing regimens |
| CN1740197B (zh) * | 2004-08-26 | 2010-05-12 | 辉阳科技美国公司 | 具有全新空间构象且功效增强的重组干扰素、其制备方法及应用 |
| JP2006083126A (ja) * | 2004-09-17 | 2006-03-30 | Institute Of Physical & Chemical Research | タンパク質の結晶化試薬キット及び試薬キットを利用した結晶化スクリーニング方法 |
| WO2006134497A2 (en) | 2005-03-09 | 2006-12-21 | Guangwen Wei | Uses of recombinant super-compound interferons |
| CN1710197B (zh) * | 2005-06-17 | 2011-06-22 | 徐州师范大学 | 可变色彩色纤维防伪纸 |
| JP4744979B2 (ja) * | 2005-08-24 | 2011-08-10 | 独立行政法人理化学研究所 | ゼオライトを用いたタンパク質結晶化方法 |
| JP2008050225A (ja) * | 2006-08-25 | 2008-03-06 | National Institute Of Advanced Industrial & Technology | たんぱく質の合理的な結晶化条件探索法 |
| CN102101886A (zh) | 2009-12-18 | 2011-06-22 | 四川辉阳生命工程股份有限公司 | 构象改变的重组干扰素晶体、其三维结构及应用 |
| US20130184437A9 (en) | 2011-06-08 | 2013-07-18 | Guangwen Wei | Design and use of new recombinant interferons with altered spatial configuration and three-dimensional structure |
-
2009
- 2009-12-18 CN CN2009102593392A patent/CN102101886A/zh active Pending
-
2010
- 2010-12-16 EP EP10836926.5A patent/EP2514761B1/en active Active
- 2010-12-16 AU AU2010333574A patent/AU2010333574B2/en active Active
- 2010-12-16 WO PCT/CN2010/002055 patent/WO2011072487A1/zh not_active Ceased
- 2010-12-16 KR KR1020127017945A patent/KR20120108985A/ko not_active Ceased
- 2010-12-16 US US13/516,947 patent/US8846025B2/en active Active
- 2010-12-16 JP JP2012543445A patent/JP2013514279A/ja active Pending
- 2010-12-16 CN CN201080057897.1A patent/CN102770447B/zh active Active
- 2010-12-16 ES ES10836926.5T patent/ES2631028T3/es active Active
- 2010-12-16 SG SG2012044889A patent/SG181785A1/en unknown
- 2010-12-16 MY MYPI2012002756A patent/MY169650A/en unknown
- 2010-12-16 CA CA2784624A patent/CA2784624C/en active Active
- 2010-12-17 US US12/971,956 patent/US8415151B2/en active Active
-
2014
- 2014-08-15 US US14/461,360 patent/US9273109B2/en active Active
-
2016
- 2016-03-23 JP JP2016058155A patent/JP2016128507A/ja active Pending
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