JP2015536905A5 - - Google Patents
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- Publication number
- JP2015536905A5 JP2015536905A5 JP2015534883A JP2015534883A JP2015536905A5 JP 2015536905 A5 JP2015536905 A5 JP 2015536905A5 JP 2015534883 A JP2015534883 A JP 2015534883A JP 2015534883 A JP2015534883 A JP 2015534883A JP 2015536905 A5 JP2015536905 A5 JP 2015536905A5
- Authority
- JP
- Japan
- Prior art keywords
- order
- milk
- lactoferrin
- treat
- rnase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000013336 milk Nutrition 0.000 claims 15
- 239000008267 milk Substances 0.000 claims 15
- 210000004080 milk Anatomy 0.000 claims 15
- 108010063045 Lactoferrin Proteins 0.000 claims 13
- 102100032241 Lactotransferrin Human genes 0.000 claims 13
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 claims 13
- 235000021242 lactoferrin Nutrition 0.000 claims 13
- 229940078795 lactoferrin Drugs 0.000 claims 13
- 150000003839 salts Chemical class 0.000 claims 10
- 238000001914 filtration Methods 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 239000003102 growth factor Substances 0.000 claims 8
- 102000006382 Ribonucleases Human genes 0.000 claims 7
- 108010083644 Ribonucleases Proteins 0.000 claims 7
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 6
- 239000012466 permeate Substances 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 3
- 239000012465 retentate Substances 0.000 claims 3
- 239000011780 sodium chloride Substances 0.000 claims 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 206010000234 Abortion spontaneous Diseases 0.000 claims 1
- 208000009206 Abruptio Placentae Diseases 0.000 claims 1
- 102100027211 Albumin Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 208000028564 B-cell non-Hodgkin lymphoma Diseases 0.000 claims 1
- 241000186000 Bifidobacterium Species 0.000 claims 1
- 208000020084 Bone disease Diseases 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 241000193403 Clostridium Species 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 206010056340 Diabetic ulcer Diseases 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 208000001951 Fetal Death Diseases 0.000 claims 1
- 208000001362 Fetal Growth Retardation Diseases 0.000 claims 1
- 206010055690 Foetal death Diseases 0.000 claims 1
- 206010070531 Foetal growth restriction Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 206010022971 Iron Deficiencies Diseases 0.000 claims 1
- 208000006816 Neonatal Sepsis Diseases 0.000 claims 1
- 206010048685 Oral infection Diseases 0.000 claims 1
- 208000005107 Premature Birth Diseases 0.000 claims 1
- 208000006399 Premature Obstetric Labor Diseases 0.000 claims 1
- 206010036590 Premature baby Diseases 0.000 claims 1
- 206010040070 Septic Shock Diseases 0.000 claims 1
- 206010052779 Transplant rejections Diseases 0.000 claims 1
- 206010047115 Vasculitis Diseases 0.000 claims 1
- 208000036142 Viral infection Diseases 0.000 claims 1
- 206010052428 Wound Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 208000007502 anemia Diseases 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 208000036654 deficiency anemia Diseases 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 231100000479 fetal death Toxicity 0.000 claims 1
- 208000030941 fetal growth restriction Diseases 0.000 claims 1
- 210000003754 fetus Anatomy 0.000 claims 1
- 208000004104 gestational diabetes Diseases 0.000 claims 1
- 230000012010 growth Effects 0.000 claims 1
- 230000003463 hyperproliferative effect Effects 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 208000018773 low birth weight Diseases 0.000 claims 1
- 231100000533 low birth weight Toxicity 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 238000005374 membrane filtration Methods 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 208000015994 miscarriage Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000011164 ossification Effects 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 201000001245 periodontitis Diseases 0.000 claims 1
- 201000008532 placental abruption Diseases 0.000 claims 1
- 201000011461 pre-eclampsia Diseases 0.000 claims 1
- 230000035935 pregnancy Effects 0.000 claims 1
- 230000002028 premature Effects 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 201000001474 proteinuria Diseases 0.000 claims 1
- 230000003537 radioprotector Effects 0.000 claims 1
- 208000023504 respiratory system disease Diseases 0.000 claims 1
- 230000036303 septic shock Effects 0.000 claims 1
- 210000004927 skin cell Anatomy 0.000 claims 1
- 208000000995 spontaneous abortion Diseases 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 208000014001 urinary system disease Diseases 0.000 claims 1
- 208000019206 urinary tract infection Diseases 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
- 230000029663 wound healing Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012904391A AU2012904391A0 (en) | 2012-10-08 | Improved process for purifying milk proteins and products thereof | |
| AU2012904391 | 2012-10-08 | ||
| AU2013204858 | 2013-04-12 | ||
| AU2013204858A AU2013204858B2 (en) | 2012-10-08 | 2013-04-12 | Improved process for purifying milk proteins and products thereof |
| PCT/AU2013/001152 WO2014056025A1 (en) | 2012-10-08 | 2013-10-08 | Improved process for purifying lactoferrin from milk and products thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015536905A JP2015536905A (ja) | 2015-12-24 |
| JP2015536905A5 true JP2015536905A5 (https=) | 2016-11-24 |
| JP6475163B2 JP6475163B2 (ja) | 2019-02-27 |
Family
ID=50476773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015534883A Expired - Fee Related JP6475163B2 (ja) | 2012-10-08 | 2013-10-08 | 乳汁からラクトフェリンを精製するための改良されたプロセスおよびその製品 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10016487B2 (https=) |
| EP (1) | EP2904006A4 (https=) |
| JP (1) | JP6475163B2 (https=) |
| KR (1) | KR20150068404A (https=) |
| CN (1) | CN104768971B (https=) |
| AU (1) | AU2013204858B2 (https=) |
| BR (1) | BR112015007674A2 (https=) |
| CA (1) | CA2886892A1 (https=) |
| IN (1) | IN2015DN02971A (https=) |
| NZ (1) | NZ631826A (https=) |
| RU (1) | RU2683228C2 (https=) |
| WO (1) | WO2014056025A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013204858B2 (en) | 2012-10-08 | 2015-06-25 | Saputo Dairy Australia Pty Limited | Improved process for purifying milk proteins and products thereof |
| CN106215174A (zh) * | 2016-08-04 | 2016-12-14 | 无锡科捷诺生物科技有限责任公司 | 一种人乳铁蛋白的制剂化制备方法 |
| US12465619B2 (en) | 2018-06-22 | 2025-11-11 | Fonterra Co-Operative Group Limited | Use of polar lipids to treat or prevent gestational diabetes mellitus |
| JP7370224B2 (ja) * | 2019-11-08 | 2023-10-27 | ライオン株式会社 | ラクトフェリン含有腸溶製剤 |
| FR3115037B1 (fr) * | 2020-10-12 | 2025-02-21 | Cie Laitiere Europeenne | Procédé de purification de fraction de protéines cationiques et fraction ainsi obtenue |
| CN113278063A (zh) * | 2021-05-13 | 2021-08-20 | 上海仁统生物科技中心 | 一种利用超滤法自初乳中获取乳铁蛋白的方法 |
| CA3229787A1 (en) * | 2021-08-23 | 2023-03-02 | Christopher HLUBB | Lactoferrin compositions and methods of use |
| PL248495B1 (pl) * | 2023-05-07 | 2025-12-22 | Polmlek Spolka Z Ograniczona Odpowiedzialnoscia | Sposób uzyskiwania laktoferyny w proszku z surowego mleka |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2584727B1 (fr) * | 1985-07-11 | 1988-06-17 | Roussel Uclaf | Procede d'extraction de proteines du lait, produits, application du procede, et compositions pharmaceutiques |
| US5221734A (en) | 1987-10-01 | 1993-06-22 | Ciba-Geigy Corporation | Process for preparing a polypeptide growth factor for milk |
| GB8729031D0 (en) * | 1987-12-11 | 1988-01-27 | Express Foods Group Ltd | Isolation of immunoglobulin rich fraction from whey |
| JP2686831B2 (ja) | 1989-09-22 | 1997-12-08 | 雪印乳業株式会社 | 鉄結合性蛋白質を分離、精製し、採取する方法 |
| ATE129125T1 (de) * | 1992-01-15 | 1995-11-15 | Campina Melkunie Bv | Verfahren zur isolierung von lactoferrin und lactoperoxidase aus milch und milchprodukten. |
| JPH05202098A (ja) | 1992-01-29 | 1993-08-10 | Snow Brand Milk Prod Co Ltd | 乳質原料から生理活性物質の製造法 |
| US5756680A (en) * | 1994-01-05 | 1998-05-26 | Sepragen Corporation | Sequential separation of whey proteins and formulations thereof |
| ATE209862T1 (de) * | 1994-02-16 | 2001-12-15 | Pharming Intellectual Pty Bv | Isolierung von lactoferrin aus milch |
| NL1005677C2 (nl) | 1997-03-27 | 1998-09-29 | Campina Melkunie Bv | Werkwijze voor het winnen van groeifactoren, of een samenstelling die één of meer groeifactoren bevat, uit melk of een derivaat daarvan. |
| US20040219225A1 (en) * | 2001-07-20 | 2004-11-04 | Kivits Marinus Gerardus Cornel | Process for obtaining growth factor (tgf-beta and igf-1), lactoperoxidase and immunoglobulins preparations from milk products having low mutual cross-contamination |
| US6875459B2 (en) * | 2001-09-10 | 2005-04-05 | Henry B. Kopf | Method and apparatus for separation of milk, colostrum, and whey |
| DK1480524T3 (da) * | 2002-03-07 | 2013-07-15 | Upfront Chromatography As | Fremgangsmåde til isolering af lactoferrin |
| FR2841747B1 (fr) * | 2002-07-02 | 2004-08-20 | Cie Laitiere Europeenne | Isolat de proteines de lait et procede pour sa preparation |
| GB0313892D0 (en) * | 2003-06-16 | 2003-07-23 | Hannah Res Inst | Control of lactation |
| US20050208638A1 (en) * | 2004-03-22 | 2005-09-22 | Chao Wu | Process for preparing bioactive protein-enriched whey products |
| US8252341B2 (en) | 2004-09-14 | 2012-08-28 | Paul Brazeau | Isolation of growth and differentiating factors from colostrum |
| US20090324733A1 (en) * | 2005-09-09 | 2009-12-31 | Murray Goulburn Co-Opeartive Co Limited | Composition of Whey Growth Factor Extract for Reducing Muscle Inflammation |
| FR2901796A1 (fr) | 2006-05-31 | 2007-12-07 | Lab Francais Du Fractionnement | Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait |
| JP5276004B2 (ja) * | 2006-11-10 | 2013-08-28 | マリー ゴールバーン シーオー−オペレイティブ シーオー．リミテッド | アンギオゲニンの調製方法 |
| EP2293678A4 (en) * | 2008-05-14 | 2011-06-22 | Agriculture Victoria Serv Pty | ANGIOGENIC-ENRICHED MILK FRACTIONS |
| RU2579661C2 (ru) * | 2009-01-28 | 2016-04-10 | Жан-Поль ПЕРРОДЭН | Способ производства лактоферрина, фракция, содержащая лактоферрин, и ее применения |
| WO2010122988A1 (ja) * | 2009-04-23 | 2010-10-28 | 株式会社ジェイ・エム・エス | 医療用コネクタ構造 |
| JPWO2012015037A1 (ja) * | 2010-07-30 | 2013-09-12 | 森永乳業株式会社 | 抗菌活性増強剤 |
| AU2013204858B2 (en) | 2012-10-08 | 2015-06-25 | Saputo Dairy Australia Pty Limited | Improved process for purifying milk proteins and products thereof |
-
2013
- 2013-04-12 AU AU2013204858A patent/AU2013204858B2/en active Active
- 2013-10-08 CA CA2886892A patent/CA2886892A1/en not_active Abandoned
- 2013-10-08 WO PCT/AU2013/001152 patent/WO2014056025A1/en not_active Ceased
- 2013-10-08 CN CN201380055328.7A patent/CN104768971B/zh not_active Expired - Fee Related
- 2013-10-08 EP EP13844731.3A patent/EP2904006A4/en not_active Withdrawn
- 2013-10-08 US US14/434,324 patent/US10016487B2/en active Active
- 2013-10-08 NZ NZ631826A patent/NZ631826A/en not_active IP Right Cessation
- 2013-10-08 RU RU2015116933A patent/RU2683228C2/ru not_active IP Right Cessation
- 2013-10-08 KR KR1020157010356A patent/KR20150068404A/ko not_active Abandoned
- 2013-10-08 BR BR112015007674A patent/BR112015007674A2/pt not_active Application Discontinuation
- 2013-10-08 JP JP2015534883A patent/JP6475163B2/ja not_active Expired - Fee Related
-
2015
- 2015-04-09 IN IN2971DEN2015 patent/IN2015DN02971A/en unknown
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