JP2015535607A - 生体試料を収集するための医療装置および方法 - Google Patents
生体試料を収集するための医療装置および方法 Download PDFInfo
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
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- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
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Abstract
Description
本出願は、2013年3月29日出願の米国仮出願第61/806,667号および2012年11月20日出願の米国仮出願第61/728,682号に対する優先権を主張する。これらの内容は全体として本明細書に参考として組み込まれる。
110 細長管状部材、細長管状体
112 近位端
113 開口部
114 遠位端
116 ねじ山、くびれ部
118 区画
120 フィルターアセンブリ
122 フィルター膜
124 基部部材
126 平面状底面
128 上方に延びる壁
130 蓋
200 圧縮カバー
220 第2のフィルターアセンブリ
222 フィルター膜
224 基部部材
228 上方に延びる壁
229 ベローズ
310 試料
320 フィルターアセンブリ
322 フィルター膜
324 基部部材
400 圧縮カバー
410 平面状上面
412 側壁
430 ベローズ
510B 管状部材
510a 管状部材、細長管状ピース
510b 管状部材、細長管状ピース
512a シェルフ、リップ
512b シェルフ、リップ
522 フィルター膜
522a ピーク部
522b 谷部
530 ポスト
532 凹部
534 リブ
600 カバー
610 管状体、細長管状部材
612 プランジャ
612b シェルフ
614 プランジャ
622 フィルター膜
622a 構造的補強特徴、シェルフ
622b 支柱
702 試料投入チャンバ、細長管状体
704 支持ポスト、支持部材
705 チャネル、スロット
710 細長管状部材、細長管状体、チューブ
722 支持部材、構成部品、フィルター膜
810a チューブ、細長管状部材
810b チューブ、細長管状部材
812 シェルフ
830a 第1のキャップ
830b 第2のキャップ
910 細長管状体
910a 第1のチューブ、第1の細長管状体
910a’ 位置
910a’’ 位置
910a’’’ 位置
910b 第2の細長管状体
922 フィルター膜
1010 細長管状体
1012 構造的保持特徴
1013 遠位端
1014 閉鎖機構
1016 係止機構
1110 細長管状体
1112 出口
1113 非平面
1114 サイドポート
1120 フィルター膜、下側濾過面
1122 上側濾過面、上面
1123 下側濾過面、下面
1124 縁部分、ハウジング
1704 支持部材
1705 チャネル
2000 外付け注射器
2001 リザーバ
2300 細胞ブロック装置
2310 細長管状体
2312 近位端
2314 遠位端
2318 区画
2320 細長管状体、試料投入チャンバ
2330 カバー
2340 フィルター膜、フィルターアセンブリ
2412 構造的保持特徴
2413 遠位端
2414 閉鎖機構
2416 係止機構
2600 コンテナ
2900 細胞ブロック装置
2910 細長管状体
2912 構造的保持特徴、リップ、近位端
2914 遠位端
2918 区画
2920 試料投入チャンバ、試料投入チューブ
2924 遠位部分、下端
2930 カバー
2940 濾過挿入物、フィルター膜
2940’ 切片、スライス
2950 クランプ部材
2952 側壁
2953 孔
2954 側壁
2960 濾過後キャップ
3200 コンテナ
3210 上面
3220 底面
3500 モールド
3510 上部
3520 底部
3522 区画
3600 スライド
3952 側壁
3954 側壁
4160 濾過後キャップ
4162 発泡体
4164 ワックス
4166 フィルター
4360 濾過後キャップ
4362 発泡体
4364 ワックス/LDPE部分
4440 フィルター膜
4442 スロット
4460 カバー
4462 フランジ
4466 表面
4468 垂直リブ
4740 フィルター膜
4742 溝
4745 孔
4940 フィルター膜
4950 入口
4966 多孔質フィルター膜、多孔質フィルターメッシュ
4970 バルブ
5210 細長管状体、外部チューブ
5212 構造的保持特徴
5220 試料投入チューブ、試料投入チャンバ、管状体
5224 下端、遠位部分
5230 支持キャップ
5240 フィルター膜
5242 溝
5250 クランプ
5253 孔
5260 ステムバルブ、バルブステム
5262 球根状遠位端、ステムバルブ
5270 ばね
5520 試料投入チャンバ
5520’ 孔、開口部
5540 フィルター膜
5560 回転円板バルブ
5560’ 円板バルブ孔
5620 試料投入チャンバ
5620’ 開口部
5640 フィルター膜
5660a 中実部材
5660b’ 摺動バルブ孔、中央孔
5760a 上部ピース
5760b 下部ピース
5920’ サブチャンバ
5940 フィルター膜
5940’ 一致孔
6140 一体成形型被保持物チャンバ、フィルター膜
6142 密封リング
6150 入口
6170 膜
6172 薄い壁膜、リザーバ、キャビティ、膜壁
6200 コンテナ、容器
6201 蓋
6202 底部
6203 スリーブ
6204 スリーブ
6240 フィルター膜
6250 入口
6255 コンテナポート
6270 膜
6272 リザーバ
Claims (20)
- 上面および底面を有するフィルター膜と、
縁であって、
前記フィルター膜に外接し、その内部に配置される溝を備える、上方に延びる側壁、および
前記フィルター膜の前記底面に隣接して配置される前記縁の底面を有する縁と
を備え、
前記フィルター膜および縁は切片化可能である、生物学的フィルター。 - 下方に延びる側壁および中心部分を有するフランジを有するカバーをさらに含み、前記中心部分は隆起した表面を有する、請求項1に記載の生物学的フィルター。
- 前記隆起した表面はドームである、請求項2に記載の生物学的フィルター。
- 前記隆起した表面は、前記フランジの下に配置される先端を有する、請求項3に記載の生物学的フィルター。
- 前記カバーのフランジはリップ部分を備え、前記リップ部分は前記縁の溝に嵌め合い係合するように構成される、請求項2に記載の生物学的フィルター。
- 前記縁の前記底面は前記側壁間に垂直に延び、複数の孔を備える、請求項2に記載の生物学的フィルター。
- 前記カバーの側壁は複数のリブを備える、請求項1に記載の生物学的フィルター。
- 前記縁の少なくとも一部は波状のピーク部および谷部を備える、請求項1に記載の生物学的フィルター。
- 前記縁の少なくとも一部は平坦な表面を備える、請求項1に記載の生物学的フィルター。
- 前記縁はワックスから構成される、請求項1に記載の生物学的フィルター。
- それらの間の内部空間を規定する近位端および遠位端を有する試料投入チャンバと、
前記試料投入チャンバの前記遠位端に配置されるフィルター膜と、
前記試料投入チャンバ内に配置され、閉鎖位置に付勢されて前記試料投入チャンバと前記フィルター膜との間の流体連通を防ぐ、バルブステムと
を備える医療装置。 - クランプをさらに備え、前記フィルター膜は前記クランプにより保持される、請求項11に記載の医療装置。
- 前記クランプは、少なくとも1つの孔を有する底面および側壁を備える、請求項12に記載の医療装置。
- 前記クランプは螺合により前記試料投入チャンバに取り付けられる、請求項12に記載の医療装置。
- 前記バルブステムは、前記試料投入チャンバを超えて近位方向に延びる、請求項11に記載の医療装置。
- 前記バルブステムはばねを受容するための孔を備える、請求項11に記載の医療装置。
- 前記ばねは前記試料投入チャンバの前記近位端を横切って延び、前記側壁と係合する、請求項16に記載の医療装置。
- キャップをさらに備え、前記キャップは前記バルブステムの近位端と係合して前記バルブを開き、前記試料投入チャンバと前記フィルター膜とを流体連通可能にする、請求項11に記載の医療装置。
- 前記試料投入チャンバの前記遠位端は、前記近位端よりも幅狭の開口部を有する、請求項11に記載の医療装置。
- 前記バルブステムは、前記閉鎖位置にあるとき、前記試料投入チャンバの前記側壁と嵌め合い係合する、請求項11に記載の医療装置。
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