JP2015534810A5 - - Google Patents

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JP2015534810A5
JP2015534810A5 JP2015539940A JP2015539940A JP2015534810A5 JP 2015534810 A5 JP2015534810 A5 JP 2015534810A5 JP 2015539940 A JP2015539940 A JP 2015539940A JP 2015539940 A JP2015539940 A JP 2015539940A JP 2015534810 A5 JP2015534810 A5 JP 2015534810A5
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pen
microfluidic device
housing
micro
medium
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JP2015539940A
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JP2015534810A (ja
JP6529908B2 (ja
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JP2015539940A 2012-10-31 2013-10-30 生物学的微小物体用ペン Active JP6529908B2 (ja)

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Application Number Priority Date Filing Date Title
JP2019092189A JP6902572B2 (ja) 2012-10-31 2019-05-15 生物学的微小物体用ペン

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261720956P 2012-10-31 2012-10-31
US61/720,956 2012-10-31
US14/060,117 2013-10-22
US14/060,117 US9857333B2 (en) 2012-10-31 2013-10-22 Pens for biological micro-objects
PCT/US2013/067479 WO2014070873A1 (en) 2012-10-31 2013-10-30 Pens for biological micro-objects

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Publications (3)

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JP2015534810A JP2015534810A (ja) 2015-12-07
JP2015534810A5 true JP2015534810A5 (OSRAM) 2016-12-08
JP6529908B2 JP6529908B2 (ja) 2019-06-12

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JP2019092189A Active JP6902572B2 (ja) 2012-10-31 2019-05-15 生物学的微小物体用ペン
JP2021102379A Ceased JP2021141902A (ja) 2012-10-31 2021-06-21 生物学的微小物体用ペン

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JP2021102379A Ceased JP2021141902A (ja) 2012-10-31 2021-06-21 生物学的微小物体用ペン

Country Status (11)

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US (4) US9857333B2 (OSRAM)
EP (2) EP3885043A1 (OSRAM)
JP (3) JP6529908B2 (OSRAM)
KR (3) KR102340691B1 (OSRAM)
CN (2) CN108070582B (OSRAM)
AU (3) AU2013337937B2 (OSRAM)
CA (1) CA2888810C (OSRAM)
DK (1) DK2914965T3 (OSRAM)
IL (2) IL272535B2 (OSRAM)
SG (2) SG10201606540RA (OSRAM)
WO (1) WO2014070873A1 (OSRAM)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10010882B2 (en) * 2013-10-22 2018-07-03 Berkeley Lights, Inc. Microfluidic devices having isolation pens and methods of testing biological micro-objects with same
DK3473700T3 (da) * 2013-10-22 2020-07-13 Berkeley Lights Inc Mikrofluidanordninger med isoleringsaflukker og fremgangsmåder til test af biologiske mikroobjekter dermed
CA2925326C (en) 2013-10-22 2021-05-25 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
US9889445B2 (en) * 2013-10-22 2018-02-13 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
US20150166326A1 (en) 2013-12-18 2015-06-18 Berkeley Lights, Inc. Capturing Specific Nucleic Acid Materials From Individual Biological Cells In A Micro-Fluidic Device
US20150306598A1 (en) * 2014-04-25 2015-10-29 Berkeley Lights, Inc. DEP Force Control And Electrowetting Control In Different Sections Of The Same Microfluidic Apparatus
US20150306599A1 (en) 2014-04-25 2015-10-29 Berkeley Lights, Inc. Providing DEP Manipulation Devices And Controllable Electrowetting Devices In The Same Microfluidic Apparatus
US11192107B2 (en) 2014-04-25 2021-12-07 Berkeley Lights, Inc. DEP force control and electrowetting control in different sections of the same microfluidic apparatus
US20150352547A1 (en) 2014-06-06 2015-12-10 Berkeley Lights, Inc. Isolating Microfluidic Structures and Trapping Bubbles
CN107257711B (zh) 2014-12-05 2019-11-22 加利福尼亚大学董事会 具有集成网状地线的单面光致动微流体器件
CN107249742B (zh) 2014-12-08 2019-12-06 伯克利之光生命科技公司 微流体装置中定向流动的致动微流体结构及使用它的方法
SG11201704558QA (en) 2014-12-08 2017-07-28 Berkeley Lights Inc Microfluidic device comprising lateral/vertical transistor structures and process of making and using same
WO2016094522A1 (en) * 2014-12-09 2016-06-16 Berkeley Lights, Inc. Automated detection of assay-positive areas in microfluidic devices
EP3230717B1 (en) 2014-12-09 2021-08-18 Berkeley Lights, Inc. Automated detection and identification of micro-objects in microfluidic devices
AU2015360611B2 (en) 2014-12-10 2021-04-01 Berkeley Lights, Inc. Systems for operating electrokinetic devices
US9744533B2 (en) * 2014-12-10 2017-08-29 Berkeley Lights, Inc. Movement and selection of micro-objects in a microfluidic apparatus
AU2016226008A1 (en) * 2015-03-04 2017-10-26 Berkeley Lights, Inc. Generation and selection of embryos in vitro
HK1246623A1 (zh) * 2015-03-04 2018-09-14 伯克利之光生命科技公司 体外胚胎的生殖和选择
AU2016250689B2 (en) * 2015-04-22 2021-07-08 Berkeley Lights, Inc. Microfluidic cell culture
SG11201708557TA (en) 2015-04-22 2017-11-29 Berkeley Lights Inc Freezing and archiving cells on a microfluidic device
US10751715B1 (en) 2015-04-22 2020-08-25 Berkeley Lights, Inc. Microfluidic reporter cell assay methods and kits thereof
US10101250B2 (en) 2015-04-22 2018-10-16 Berkeley Lights, Inc. Manipulation of cell nuclei in a micro-fluidic device
TWI744230B (zh) * 2015-04-22 2021-11-01 美商伯克利之光生命科技公司 微流體器件及在該微流體器件中培養生物細胞之方法
US10799865B2 (en) 2015-10-27 2020-10-13 Berkeley Lights, Inc. Microfluidic apparatus having an optimized electrowetting surface and related systems and methods
SG11201802968VA (en) * 2015-10-27 2018-05-30 Berkeley Lights Inc Microfluidic electrowetting device apparatus having a covalently bound hydrophobic surface
IL299366A (en) 2015-11-23 2023-02-01 Berkeley Lights Inc In situ-generated microfluidic isolation structures, kits and methods of use thereof
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
CN114878807A (zh) 2015-12-08 2022-08-09 伯克利之光生命科技公司 微流体设备和试剂盒及其使用方法
JP6964590B2 (ja) * 2015-12-30 2021-11-10 バークレー ライツ,インコーポレイテッド 光学的に駆動される対流及び変位のマイクロ流体デバイス、そのキット及び方法
TWI808934B (zh) 2015-12-31 2023-07-21 美商伯克利之光生命科技公司 經工程化以表現促發炎多肽之腫瘤浸潤細胞
TWI756199B (zh) 2016-01-15 2022-03-01 美商伯克利之光生命科技公司 製造患者專ㄧ性抗癌治療劑之方法及使用該治療劑之治療方法
WO2017160991A1 (en) 2016-03-16 2017-09-21 Lavieu Gregory G Methods, systems and devices for selection and generation of genome edited clones
EP3922716A1 (en) * 2016-03-17 2021-12-15 Berkeley Lights, Inc. Selection and cloning of t lymphocytes in a microfluidic device
CN115896099A (zh) 2016-03-31 2023-04-04 伯克利之光生命科技公司 核酸稳定试剂、试剂盒及其使用方法
US10675625B2 (en) * 2016-04-15 2020-06-09 Berkeley Lights, Inc Light sequencing and patterns for dielectrophoretic transport
EP3446102B1 (en) 2016-04-15 2025-12-10 Bruker Cellular Analysis, Inc. Methods, systems, computer program and non-transitory computer-readable medium for in-pen assays
AU2017271673B2 (en) 2016-05-26 2022-04-14 Berkeley Lights, Inc. Covalently modified surfaces, kits, and methods of preparation and use
WO2017220534A1 (en) * 2016-06-21 2017-12-28 Quantumdx Group Limited Improved target cell concentration using dielectrophoresis (dep)
EP3487510B1 (en) 2016-07-21 2023-07-19 Berkeley Lights, Inc. Sorting of t lymphocytes in a microfluidic device
WO2018064640A1 (en) 2016-10-01 2018-04-05 Berkeley Lights, Inc. Dna barcode compositions and methods of in situ identification in a microfluidic device
KR102669330B1 (ko) 2016-12-01 2024-05-28 버클리 라잇츠, 인크. 미세유체 디바이스에서의 마이크로-객체의 자동화된 검출 및 재포지셔닝
KR102551430B1 (ko) 2016-12-01 2023-07-05 버클리 라잇츠, 인크. 미세-객체들을 이미징하기 위한 장치들, 시스템들 및 방법들
JP7356351B2 (ja) 2016-12-12 2023-10-04 エクセラ・バイオサイエンシーズ・インコーポレイテッド マイクロキャピラリーアレイを使用したスクリーニングのための方法およびシステム
EP3562796B1 (en) 2016-12-30 2023-04-19 Xcella Biosciences, Inc. Multi-stage sample recovery system
EP3562594A4 (en) 2016-12-30 2020-09-09 The Regents of University of California PROCESSES FOR SELECTING AND GENERATING T-LYMPHOCYTES MODIFIED BY THE GENOME
JPWO2018207454A1 (ja) * 2017-05-12 2020-03-19 株式会社ニコン 対象物操作装置、及び対象物操作方法
KR20200026878A (ko) 2017-06-06 2020-03-11 지머젠 인코포레이티드 균류 균주를 개량하기 위한 htp 게놈 공학 플랫폼
EP4620977A3 (en) 2017-07-21 2025-12-17 Bruker Cellular Analysis, Inc. Antigen-presenting synthetic surfaces, covalently functionalized surfaces, activated t cells, and uses thereof
US11684917B2 (en) 2017-09-29 2023-06-27 Schlumberger Technology Corporation Microfluidic technique for detection of multi-contact miscibility
WO2019075476A2 (en) 2017-10-15 2019-04-18 Berkeley Lights, Inc. METHODS, SYSTEMS AND KITS FOR ENCLOSED TESTS
CN108300654B (zh) * 2018-02-09 2021-08-17 华中科技大学同济医学院附属协和医院 评估可移动生物活体药代动力学的芯片及实时检测系统
DE102018203047A1 (de) * 2018-03-01 2019-09-05 Robert Bosch Gmbh Mikrofluidische Vorrichtung
WO2019173276A1 (en) * 2018-03-06 2019-09-12 Waters Technologies Corporation A high surface area chromatographic device with low pressure drop
KR20210015947A (ko) 2018-05-31 2021-02-10 버클리 라잇츠, 인크. 미세유체 디바이스에서의 마이크로-객체의 자동 검출 및 특성화
WO2019236848A1 (en) 2018-06-06 2019-12-12 Zymergen Inc. Manipulation of genes involved in signal transduction to control fungal morphology during fermentation and production
CA3054046A1 (en) * 2018-09-04 2020-03-04 The Governing Council Of The University Of Toronto Patterned optoelectronic tweezers
GB2577074B (en) 2018-09-12 2022-06-01 Quantumdx Group Ltd Microfluidic device with DEP arrays
WO2020056339A1 (en) * 2018-09-14 2020-03-19 Berkeley Lights, Inc. Methods for assaying binding affinity
EP3853352A4 (en) 2018-09-21 2022-08-10 Berkeley Lights, Inc. FUNCTIONALIZED TRUCK PLATE, PROCESS FOR ITS MANUFACTURE AND ITS USE
WO2020076852A1 (en) * 2018-10-10 2020-04-16 Stamm Vegh Corporation Continuous flow microbioreactor
EP3863757A4 (en) 2018-10-11 2022-07-20 Berkeley Lights, Inc. SYSTEMS AND METHODS FOR IDENTIFICATION OF OPTIMIZED PROTEIN PRODUCTION AND KITS THEREFORE
EP3867353A4 (en) 2018-10-18 2022-07-27 Berkeley Lights, Inc. PROTO-ANTIGEN PRESENTING SYNTHETIC SURFACES, ACTIVATED T-CELLS AND THEIR USES
JP2022506154A (ja) 2018-11-01 2022-01-17 バークレー ライツ,インコーポレイテッド マイクロ流体環境において生体細胞をアッセイする方法
SG11202104544WA (en) 2018-11-19 2021-06-29 Berkeley Lights Inc Microfluidic device with programmable switching elements
ES2987081T3 (es) 2018-12-06 2024-11-13 Xcella Biosciences Inc Carga lateral de arreglos de microcapilares
WO2020168258A1 (en) 2019-02-15 2020-08-20 Berkeley Lights, Inc. Laser-assisted repositioning of a micro-object and culturing of an attachment-dependent cell in a microfluidic environment
WO2020223555A1 (en) 2019-04-30 2020-11-05 Berkeley Lights, Inc. Methods for encapsulating and assaying cells
US20220226829A1 (en) * 2019-06-05 2022-07-21 Amgen Inc. Systems for performing cellular analysis and related devices for conditioning environments adjacent chips in such systems
CN110618095A (zh) * 2019-11-08 2019-12-27 武汉大学深圳研究院 一种光流控水体溶解氧探测器
KR20220113683A (ko) 2019-11-17 2022-08-16 버클리 라잇츠, 인크. 생물학적 샘플의 분석을 위한 시스템 및 방법
KR20220137692A (ko) 2020-02-03 2022-10-12 스탬 베그 코포레이션 3d 프린팅을 위한 플랫폼, 시스템, 및 디바이스
AU2021235901A1 (en) 2020-03-09 2022-10-06 Berkeley Lights, Inc. Methods, systems and kits for in-pen assays
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
CA3189006A1 (en) 2020-09-07 2022-03-10 Matthew Asuka KUBIT Methods of assaying a biological cell
WO2023032827A1 (ja) 2021-08-31 2023-03-09 キヤノン株式会社 ポリウレタンを含む非発泡の成形体
EP4239333A1 (en) 2022-03-03 2023-09-06 Lonza Biologics plc Method for selecting clonal cells expressing correctly assembled multi-specific binding molecules
EP4598680A1 (en) * 2022-10-03 2025-08-13 Bruker Cellular Analysis, Inc. Micro-object displacement within a microfluidic environment

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997040385A1 (en) 1996-04-25 1997-10-30 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US6294063B1 (en) 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
US6942776B2 (en) 1999-05-18 2005-09-13 Silicon Biosystems S.R.L. Method and apparatus for the manipulation of particles by means of dielectrophoresis
JP2003524738A (ja) 1999-06-28 2003-08-19 カリフォルニア インスティチュート オブ テクノロジー 微細製作エラストマーバルブおよびポンプシステム
US20030007894A1 (en) 2001-04-27 2003-01-09 Genoptix Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles
ITTO20010411A1 (it) 2001-05-02 2002-11-02 Silicon Biosystems S R L Metodo e dispositivo per l'esecuzione di test e saggi ad alta processivita' ed alto valore biologico su cellule e/o composti.
US7075162B2 (en) * 2001-08-30 2006-07-11 Fluidigm Corporation Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes
CN1291035C (zh) * 2001-10-09 2006-12-20 清华大学 用于样品制备和分析的集成式生物芯片系统
US7312085B2 (en) 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
CA2480728A1 (en) 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
US6958132B2 (en) 2002-05-31 2005-10-25 The Regents Of The University Of California Systems and methods for optical actuation of microfluidics based on opto-electrowetting
US7790443B2 (en) 2002-08-27 2010-09-07 Vanderbilt University Bioreactors with substance injection capacity
WO2004065618A2 (en) 2003-01-16 2004-08-05 Thermogenic Imaging Methods and devices for monitoring cellular metabolism in microfluidic cell-retaining chambers
CA2521171C (en) 2003-04-03 2013-05-28 Fluidigm Corp. Microfluidic devices and methods of using same
DE112004001376D2 (de) * 2003-05-19 2006-04-13 Knoell Hans Forschung Ev Vorrichtung und Verfahren zur Strukturierung von Flüssigkeiten und zum zudosieren von Reaktionsflüssigkeiten zu in Separationsmedium eingebetteten Flüssigkeitskompartimenten
JP4328168B2 (ja) 2003-10-02 2009-09-09 ソニー株式会社 毛細管現象を利用する物質間の相互作用検出部と該検出部を用いる方法及びバイオアッセイ用基板
US7425253B2 (en) 2004-01-29 2008-09-16 Massachusetts Institute Of Technology Microscale sorting cytometer
WO2005100541A2 (en) * 2004-04-12 2005-10-27 The Regents Of The University Of California Optoelectronic tweezers for microparticle and cell manipulation
US20080257735A1 (en) 2004-09-24 2008-10-23 Regents Of The University Of California Microfluidic Device for Enabling the Controlled Growth of Cells and Methods Relating to Same
US20060091015A1 (en) 2004-11-01 2006-05-04 Applera Corporation Surface modification for non-specific adsorption of biological material
EP1851304A4 (en) 2005-02-23 2009-10-21 Cook William A Australia CULTURE DEVICE
ES2865180T3 (es) 2005-07-07 2021-10-15 Univ California Aparato para formación de cultivo celular
CA2616504A1 (en) 2005-08-19 2007-03-01 The Regents Of The University Of California Microfluidic methods for diagnostics and cellular analysis
CN101548004A (zh) * 2005-08-19 2009-09-30 加利福尼亚大学董事会 用于诊断学和细胞分析的微流体方法
WO2007102839A2 (en) 2005-10-27 2007-09-13 Applera Corporation Optoelectronic separation of biomolecules
US8124015B2 (en) 2006-02-03 2012-02-28 Institute For Systems Biology Multiplexed, microfluidic molecular assay device and assay method
EP2125219B1 (en) 2007-01-19 2016-08-10 Fluidigm Corporation High precision microfluidic devices and methods
WO2008119066A1 (en) 2007-03-28 2008-10-02 The Regents Of The University Of California Single-sided lateral-field and phototransistor-based optoelectronic tweezers
EP2150350B1 (en) 2007-05-24 2012-04-25 The Regents of the University of California Integrated fluidics devices with magnetic sorting
EP2078958A1 (en) 2007-10-25 2009-07-15 Koninklijke Philips Electronics N.V. A reconfigurable microfluidic filter based on eletric fields
BRPI0910898B1 (pt) 2008-04-03 2021-09-14 The Regents Of The University Of California Dispositivo eletrocinético de corrente alternada para isolar analitos em nano escala a partir de amostras de alta condutividade em uma região de alto campo dieletroforético (dep), método para separar analitos em nano escala a partir de grandes entidades em uma amostra de alta condutância e sistema para separação de material biológico
JP2009273459A (ja) * 2008-04-15 2009-11-26 Tosoh Corp 細胞選別装置、およびそれを用いた細胞選別方法
EP2279238A2 (en) 2008-04-21 2011-02-02 Cell Kinetics, Ltd. Flat cell carriers with cell traps
KR101464023B1 (ko) 2008-07-28 2014-11-20 에이저 시스템즈 엘엘시 가변 보상된 플라이 하이트 측정용 시스템들 및 방법들
GB2464300A (en) 2008-10-10 2010-04-14 Univ Dublin City Microfluidic multiplexed cellular and molecular analysis device and method
JP2012522518A (ja) 2009-04-03 2012-09-27 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 細胞および生体粒子を選別するための方法および装置
US20100273681A1 (en) 2009-04-27 2010-10-28 Wisconsin Alumni Research Foundation Combinatorial chemistry reaction cell with optical tweezers
GB0909923D0 (en) 2009-06-09 2009-07-22 Oxford Gene Tech Ip Ltd Picowell capture devices for analysing single cells or other particles
GB0910330D0 (en) * 2009-06-16 2009-07-29 Univ Leiden A biological microfluidics chip and related methods
JP2011000079A (ja) * 2009-06-19 2011-01-06 Univ Of Tokyo 粒子を操作する方法及びマイクロ流体装置
CN201834907U (zh) * 2010-04-15 2011-05-18 四川国兴盛生物科技有限公司 半封闭式围栏
WO2011149032A1 (ja) 2010-05-26 2011-12-01 東ソー株式会社 生体試料固定装置
CN101947124B (zh) 2010-06-25 2012-07-04 博奥生物有限公司 一种集成式微流控芯片装置及其使用方法
EP2589952A4 (en) * 2010-06-30 2014-05-14 Tosoh Corp PARTICLE FASTENING STRUCTURE AND PARTICLE ANALYSIS DEVICE
US10087408B2 (en) 2010-07-07 2018-10-02 The University Of British Columbia System and method for microfluidic cell culture
US9188593B2 (en) 2010-07-16 2015-11-17 The University Of British Columbia Methods for assaying cellular binding interactions
US9533306B2 (en) 2010-08-02 2017-01-03 The Regents Of The University Of California Single sided continuous optoelectrowetting (SCEOW) device for droplet manipulation with light patterns
JP5804620B2 (ja) * 2010-08-09 2015-11-04 一般財団法人生産技術研究奨励会 電気的機能を持つマイクロチャンバーアレイ装置およびそれを用いた検査対象物解析方法
WO2012037030A2 (en) 2010-09-14 2012-03-22 The Regents Of The University Of California Method and device for isolating cells from heterogeneous solution using microfluidic trapping vortices
EP3035031B1 (en) 2010-12-03 2022-06-01 Cellply S.R.L. Microanalysis of cellular function
WO2012072823A1 (en) 2010-12-03 2012-06-07 Mindseeds Laboratories Srl Rapid screening of monoclonal antibodies
CN102580794B (zh) * 2011-01-13 2014-03-19 博奥生物有限公司 可定位细胞及生物体的微流控芯片及其应用
US9227200B2 (en) 2011-06-03 2016-01-05 The Regents Of The University Of California Microfluidic devices with flexible optically transparent electrodes
ES2797448T3 (es) 2011-08-01 2020-12-02 Bio Rad Laboratories Sistema de captura de células
US10626435B2 (en) 2012-03-28 2020-04-21 Northeastern University Nanofluidic device for isolating, growing, and characterizing microbial cells
EP2978855B1 (en) 2013-03-28 2021-01-13 The University of British Columbia Microfluidic devices and methods for use thereof in multicellular assays of secretion

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