JP2015534564A5 - - Google Patents
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- JP2015534564A5 JP2015534564A5 JP2015535889A JP2015535889A JP2015534564A5 JP 2015534564 A5 JP2015534564 A5 JP 2015534564A5 JP 2015535889 A JP2015535889 A JP 2015535889A JP 2015535889 A JP2015535889 A JP 2015535889A JP 2015534564 A5 JP2015534564 A5 JP 2015534564A5
- Authority
- JP
- Japan
- Prior art keywords
- lingo
- combination
- combination according
- antibody molecule
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261711638P | 2012-10-09 | 2012-10-09 | |
| US61/711,638 | 2012-10-09 | ||
| PCT/US2013/063873 WO2014058875A2 (en) | 2012-10-09 | 2013-10-08 | Combination therapies and uses for treatment of demyelinating disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017247590A Division JP2018044014A (ja) | 2012-10-09 | 2017-12-25 | 脱髄障害の治療のための併用療法および使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015534564A JP2015534564A (ja) | 2015-12-03 |
| JP2015534564A5 true JP2015534564A5 (https=) | 2016-11-24 |
Family
ID=49484444
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015535889A Withdrawn JP2015534564A (ja) | 2012-10-09 | 2013-10-08 | 脱髄障害の治療のための併用療法および使用 |
| JP2017247590A Withdrawn JP2018044014A (ja) | 2012-10-09 | 2017-12-25 | 脱髄障害の治療のための併用療法および使用 |
| JP2020004952A Withdrawn JP2020055881A (ja) | 2012-10-09 | 2020-01-16 | 脱髄障害の治療のための併用療法および使用 |
| JP2021176294A Pending JP2022023182A (ja) | 2012-10-09 | 2021-10-28 | 脱髄障害の治療のための併用療法および使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017247590A Withdrawn JP2018044014A (ja) | 2012-10-09 | 2017-12-25 | 脱髄障害の治療のための併用療法および使用 |
| JP2020004952A Withdrawn JP2020055881A (ja) | 2012-10-09 | 2020-01-16 | 脱髄障害の治療のための併用療法および使用 |
| JP2021176294A Pending JP2022023182A (ja) | 2012-10-09 | 2021-10-28 | 脱髄障害の治療のための併用療法および使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20150238602A1 (https=) |
| EP (2) | EP3750560A3 (https=) |
| JP (4) | JP2015534564A (https=) |
| KR (2) | KR102257645B1 (https=) |
| CN (2) | CN104870014A (https=) |
| AU (3) | AU2013329421A1 (https=) |
| BR (1) | BR112015007780A2 (https=) |
| CA (1) | CA2887682A1 (https=) |
| EA (1) | EA201590709A1 (https=) |
| HK (1) | HK1213794A1 (https=) |
| IL (2) | IL238117B (https=) |
| MX (2) | MX2015004436A (https=) |
| WO (1) | WO2014058875A2 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2982695T3 (da) | 2008-07-09 | 2019-05-13 | Biogen Ma Inc | Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf |
| CN104470541A (zh) | 2012-05-14 | 2015-03-25 | 比奥根艾迪克Ma公司 | 用于治疗涉及运动神经元的疾患的lingo-2拮抗剂 |
| US20170283804A1 (en) * | 2014-09-19 | 2017-10-05 | Ionis Pharmaceuticals, Inc. | Antisense compounds and uses thereof |
| EP4056179A1 (en) | 2014-12-11 | 2022-09-14 | Actelion Pharmaceuticals Ltd | Dosing regimen for ponesimod, a selective s1p1 receptor agonist |
| MA41139B1 (fr) | 2014-12-11 | 2026-02-27 | Laboratoires Juvise Pharmaceuticals | Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque |
| JP2018504400A (ja) * | 2015-01-08 | 2018-02-15 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | Lingo‐1拮抗薬及び脱髄障害の治療のための使用 |
| WO2016156468A1 (en) | 2015-03-31 | 2016-10-06 | Vhsquared Limited | Polypeptides |
| HK1250011A1 (zh) | 2015-03-31 | 2018-11-23 | Sorriso Pharmaceuticals, Inc. | 具有蛋白酶可切割接头的肽构建体 |
| AU2016270373A1 (en) | 2015-06-05 | 2018-01-04 | Vertex Pharmaceuticals Incorporated | Triazoles for the treatment of demyelinating diseases |
| JP7149257B2 (ja) * | 2016-07-13 | 2022-10-06 | バイオジェン・エムエイ・インコーポレイテッド | Lingo-1アンタゴニストの投与計画及び脱髄障害の処置のための使用 |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| HUE071047T2 (hu) | 2016-08-31 | 2025-07-28 | Mapi Pharma Ltd | Glatiramer-acetátot tartalmazó depórendszerek |
| WO2018106646A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Aminotriazoles for the treatment of demyelinating diseases |
| WO2018106643A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Heterocyclic azoles for the treatment of demyelinating diseases |
| WO2018106641A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Pyrazoles for the treatment of demyelinating diseases |
| CN110382052A (zh) | 2017-03-26 | 2019-10-25 | Mapi医药公司 | 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统 |
| US20200181235A1 (en) * | 2017-05-15 | 2020-06-11 | Oncoimmune, Inc. | Methods of use of soluble cd24 for neuroprotection and remyelination |
| US11412968B2 (en) | 2017-09-12 | 2022-08-16 | Get Together, Inc | System and method for a digital therapeutic delivery of generalized clinician tips (GCT) |
| JP2021521189A (ja) * | 2018-04-13 | 2021-08-26 | モデハイ シェヴィオンCHEVION, Mordechai | 脱髄の治療のための組成物及び方法 |
| JP7680377B2 (ja) | 2019-06-21 | 2025-05-20 | ソリッソ ファーマシューティカルズ,インク. | ポリペプチド |
| WO2020254827A1 (en) | 2019-06-21 | 2020-12-24 | Vhsquared Limited | Polypeptides |
| KR20220063148A (ko) | 2019-06-21 | 2022-05-17 | 소리소 파마슈티컬스 인크. | 조성물 |
| CN113584041A (zh) * | 2021-04-15 | 2021-11-02 | 浙江警察学院 | 一种转基因斑马鱼(mbp:egfp)脱脊髓疾病模型的构建方法 |
| KR102898110B1 (ko) * | 2022-06-13 | 2025-12-12 | 고려대학교 산학협력단 | 키나아제 저해제를 유효성분으로 포함하는 탈수초성 질환 예방 또는 치료용 약학적 조성물 |
| WO2024249568A1 (en) | 2023-05-30 | 2024-12-05 | Paragon Therapeutics, Inc. | Alpha4beta7 integrin antibody compositions and methods of use |
| CN121889424A (zh) | 2023-08-14 | 2026-04-17 | 派拉冈医疗公司 | α4β7整联蛋白结合蛋白及使用方法 |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| AU584417B2 (en) | 1985-04-01 | 1989-05-25 | Lonza Group Ag | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| EP0436597B1 (en) | 1988-09-02 | 1997-04-02 | Protein Engineering Corporation | Generation and selection of recombinant varied binding proteins |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| WO1991000906A1 (en) | 1989-07-12 | 1991-01-24 | Genetics Institute, Inc. | Chimeric and transgenic animals capable of producing human antibodies |
| EP1690934A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| EP0585287B1 (en) | 1990-07-10 | 1999-10-13 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
| ATE352612T1 (de) | 1990-08-29 | 2007-02-15 | Pharming Intellectual Pty Bv | Homologe rekombination in säugetier-zellen |
| CA2405246A1 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with alterred binding properties |
| EP0575485A1 (en) | 1991-03-01 | 1993-12-29 | Dyax Corp. | Process for the development of binding mini-proteins |
| DK0580737T3 (da) | 1991-04-10 | 2004-11-01 | Scripps Research Inst | Heterodimere receptorbiblioteker ved anvendelse af phagemider |
| EP0519596B1 (en) | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | A method for reducing the immunogenicity of antibody variable domains |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| IE922437A1 (en) | 1991-07-25 | 1993-01-27 | Idec Pharma Corp | Recombinant antibodies for human therapy |
| AU701578B2 (en) | 1992-08-21 | 1999-02-04 | Vrije Universiteit Brussel | Immunoglobulins devoid of light chains |
| DE669986T1 (de) | 1992-11-13 | 1996-10-10 | Idec Pharma Corp | Völlig unfunktionelle konsensus-kozak-sequenzen zur säugetier-exprimierung. |
| US5736137A (en) | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
| DK0678122T3 (da) | 1993-01-12 | 2000-03-06 | Biogen Inc | Rekombinante anti-VLA4 antistofmolekyler |
| WO1994017828A2 (en) | 1993-02-09 | 1994-08-18 | Biogen, Inc. | Treatment for insulin dependent diabetes |
| DE4343034C1 (de) * | 1993-12-16 | 1995-06-08 | Rentschler Arzneimittel | Verwendung von Pentoxifyllin zur Behandlung von Multipler Sklerose |
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| US20030166282A1 (en) | 2002-02-01 | 2003-09-04 | David Brown | High potency siRNAS for reducing the expression of target genes |
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| ZA200505869B (en) * | 2003-01-24 | 2006-11-29 | Elan Pharm Inc | Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents |
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| WO2004085648A2 (en) | 2003-03-19 | 2004-10-07 | Biogen Idec Ma Inc. | Nogo receptor binding protein |
| KR20040086884A (ko) | 2003-03-22 | 2004-10-13 | 제일모직주식회사 | 난연성 열가소성 수지 조성물 |
| PT1776136E (pt) | 2004-06-24 | 2012-12-05 | Biogen Idec Inc | Tratamento de estados que envolvem desmielinização |
| US8128926B2 (en) | 2007-01-09 | 2012-03-06 | Biogen Idec Ma Inc. | Sp35 antibodies and uses thereof |
| CN101636168B (zh) * | 2007-01-09 | 2013-05-29 | 比奥根艾迪克Ma公司 | Sp35抗体及其用途 |
| DK2982695T3 (da) | 2008-07-09 | 2019-05-13 | Biogen Ma Inc | Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf |
| IT1395574B1 (it) | 2009-09-14 | 2012-10-16 | Guala Dispensing Spa | Dispositivo di erogazione |
| UA113507C2 (xx) | 2011-02-07 | 2017-02-10 | Модулятори s1p | |
| GB201103526D0 (en) * | 2011-03-02 | 2011-04-13 | Summit Corp Plc | Selective glycosidase inhibitors and uses thereof |
-
2013
- 2013-10-08 JP JP2015535889A patent/JP2015534564A/ja not_active Withdrawn
- 2013-10-08 EP EP20173044.7A patent/EP3750560A3/en not_active Withdrawn
- 2013-10-08 US US14/434,292 patent/US20150238602A1/en not_active Abandoned
- 2013-10-08 AU AU2013329421A patent/AU2013329421A1/en not_active Abandoned
- 2013-10-08 WO PCT/US2013/063873 patent/WO2014058875A2/en not_active Ceased
- 2013-10-08 KR KR1020157012062A patent/KR102257645B1/ko not_active Expired - Fee Related
- 2013-10-08 EA EA201590709A patent/EA201590709A1/ru unknown
- 2013-10-08 CN CN201380063471.0A patent/CN104870014A/zh active Pending
- 2013-10-08 HK HK16101834.0A patent/HK1213794A1/zh unknown
- 2013-10-08 BR BR112015007780A patent/BR112015007780A2/pt not_active Application Discontinuation
- 2013-10-08 CN CN201811360254.9A patent/CN109364250A/zh active Pending
- 2013-10-08 KR KR1020217015388A patent/KR20210063443A/ko not_active Ceased
- 2013-10-08 CA CA2887682A patent/CA2887682A1/en not_active Abandoned
- 2013-10-08 EP EP13780458.9A patent/EP2906240A2/en not_active Withdrawn
- 2013-10-08 MX MX2015004436A patent/MX2015004436A/es unknown
-
2015
- 2015-04-02 IL IL23811715A patent/IL238117B/en active IP Right Grant
- 2015-04-08 MX MX2020006431A patent/MX2020006431A/es unknown
-
2017
- 2017-12-25 JP JP2017247590A patent/JP2018044014A/ja not_active Withdrawn
-
2018
- 2018-02-20 US US15/900,369 patent/US20190038744A1/en not_active Abandoned
- 2018-05-25 AU AU2018203688A patent/AU2018203688A1/en not_active Abandoned
-
2019
- 2019-10-06 IL IL269852A patent/IL269852B/en unknown
- 2019-12-10 US US16/708,695 patent/US20200276303A1/en not_active Abandoned
-
2020
- 2020-01-16 JP JP2020004952A patent/JP2020055881A/ja not_active Withdrawn
- 2020-05-15 AU AU2020203196A patent/AU2020203196A1/en not_active Abandoned
- 2020-11-30 US US17/107,554 patent/US20210260185A1/en not_active Abandoned
-
2021
- 2021-10-28 JP JP2021176294A patent/JP2022023182A/ja active Pending
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