JP2015531590A5 - - Google Patents

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Publication number
JP2015531590A5
JP2015531590A5 JP2015524483A JP2015524483A JP2015531590A5 JP 2015531590 A5 JP2015531590 A5 JP 2015531590A5 JP 2015524483 A JP2015524483 A JP 2015524483A JP 2015524483 A JP2015524483 A JP 2015524483A JP 2015531590 A5 JP2015531590 A5 JP 2015531590A5
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JP
Japan
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polypeptide
amino acid
nucleic acid
isolated
mutant
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JP2015524483A
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English (en)
Japanese (ja)
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JP6297556B2 (ja
JP2015531590A (ja
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Priority claimed from PCT/US2013/052395 external-priority patent/WO2014018926A1/en
Publication of JP2015531590A publication Critical patent/JP2015531590A/ja
Publication of JP2015531590A5 publication Critical patent/JP2015531590A5/ja
Application granted granted Critical
Publication of JP6297556B2 publication Critical patent/JP6297556B2/ja
Expired - Fee Related legal-status Critical Current
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JP2015524483A 2012-07-27 2013-07-26 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物 Expired - Fee Related JP6297556B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261676842P 2012-07-27 2012-07-27
US61/676,842 2012-07-27
US201361783763P 2013-03-14 2013-03-14
US61/783,763 2013-03-14
US201361829123P 2013-05-30 2013-05-30
US61/829,123 2013-05-30
PCT/US2013/052395 WO2014018926A1 (en) 2012-07-27 2013-07-26 Methods and compositions for determining resistance to androgen receptor therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018028558A Division JP6592545B2 (ja) 2012-07-27 2018-02-21 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物

Publications (3)

Publication Number Publication Date
JP2015531590A JP2015531590A (ja) 2015-11-05
JP2015531590A5 true JP2015531590A5 (https=) 2016-09-08
JP6297556B2 JP6297556B2 (ja) 2018-03-20

Family

ID=48948536

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2015524483A Expired - Fee Related JP6297556B2 (ja) 2012-07-27 2013-07-26 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物
JP2018028558A Expired - Fee Related JP6592545B2 (ja) 2012-07-27 2018-02-21 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物
JP2019171022A Ceased JP2020072655A (ja) 2012-07-27 2019-09-20 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018028558A Expired - Fee Related JP6592545B2 (ja) 2012-07-27 2018-02-21 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物
JP2019171022A Ceased JP2020072655A (ja) 2012-07-27 2019-09-20 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物

Country Status (34)

Country Link
US (2) US9617602B2 (https=)
EP (2) EP3653733A1 (https=)
JP (3) JP6297556B2 (https=)
KR (2) KR102210183B1 (https=)
CN (3) CN104685072A (https=)
AU (3) AU2013295543B2 (https=)
BR (2) BR122017017921A2 (https=)
CA (1) CA2879926A1 (https=)
CL (1) CL2015000194A1 (https=)
CO (1) CO7280477A2 (https=)
CR (1) CR20150022A (https=)
CY (1) CY1122651T1 (https=)
DK (1) DK2877599T3 (https=)
EA (2) EA029563B1 (https=)
EC (1) ECSP15007420A (https=)
ES (1) ES2764381T3 (https=)
GT (1) GT201500019A (https=)
HR (1) HRP20192342T1 (https=)
HU (1) HUE047781T2 (https=)
IL (2) IL236844B (https=)
LT (1) LT2877599T (https=)
MX (2) MX370507B (https=)
NI (1) NI201500004A (https=)
NZ (4) NZ740700A (https=)
PE (3) PE20150644A1 (https=)
PH (2) PH12015500175B1 (https=)
PL (1) PL2877599T3 (https=)
PT (1) PT2877599T (https=)
RS (1) RS59812B1 (https=)
SG (2) SG11201500184TA (https=)
SI (1) SI2877599T1 (https=)
SM (1) SMT201900735T1 (https=)
UA (1) UA118178C2 (https=)
WO (1) WO2014018926A1 (https=)

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WO2013158972A1 (en) 2012-04-20 2013-10-24 Cepheid Methods of detecting bladder cancer
US10206911B2 (en) 2012-10-26 2019-02-19 Memorial Sloan-Kettering Cancer Center Androgen receptor variants and methods for making and using
CN105143463A (zh) * 2013-02-25 2015-12-09 诺华股份有限公司 新的雄激素受体突变
EP2964786B1 (en) 2013-03-06 2018-12-19 Cepheid Methods of detecting bladder cancer
KR20150127720A (ko) 2013-03-14 2015-11-17 유니버시티 오브 매릴랜드, 발티모어 안드로겐 수용체 하향 조절제 및 그의 용도
CA2920317A1 (en) 2013-08-12 2015-02-19 Tokai Pharmaceuticals, Inc. Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
LT4095130T (lt) 2013-10-18 2024-04-25 Novartis Ag Žymėti prostatos specifinio membranos antigeno (psma) inhibitoriai, jų naudojimas kaip vizualizavimo medžiagų ir farmacinių medžiagų prostatos vėžiui gydyti
CA2940984A1 (en) * 2014-02-05 2015-08-13 Lek Pharmaceuticals D.D. Solid pharmaceutical compositions of androgen receptor antagonists
US10774387B2 (en) 2014-05-19 2020-09-15 The Johns Hopkins University Methods for identifying androgen receptor splice variants in subjects having castration resistant prostate cancer
WO2016033114A1 (en) * 2014-08-25 2016-03-03 The Johns Hopkins University Methods and compositions related to prostate cancer therapeutics
WO2017167815A1 (en) 2016-03-29 2017-10-05 Roche Diabetes Care Gmbh Method of operating a receiver for receiving analyte data, receiver and computer program product
US11702702B2 (en) * 2016-04-15 2023-07-18 Predicine, Inc. Systems and methods for detecting genetic alterations
CN106405085B (zh) * 2016-08-31 2018-03-27 天津市泌尿外科研究所 用于检测去势抵抗性前列腺癌的elisa试剂盒及使用方法
CN106290919B (zh) * 2016-08-31 2018-03-27 天津市泌尿外科研究所 用于检测去势抵抗性前列腺癌的elisa试剂盒及使用方法
CN106198985B (zh) * 2016-08-31 2018-03-27 天津市泌尿外科研究所 用于检测去势抵抗性前列腺癌的elisa试剂盒及使用方法
CN106526185B (zh) * 2016-10-28 2018-03-30 拜尔康(天津)医药科技有限公司 用于检测去势抵抗性前列腺癌的elisa试剂盒及检测方法
US10933059B2 (en) 2016-12-16 2021-03-02 Kangpu Biopharmaceuticals. Ltd. Combination, application thereof and treatment method
KR20200074950A (ko) * 2017-10-19 2020-06-25 예일 유니버시티 약초 추출물 및 이의 조성물에 의한 안드로겐 수용체의 억제
CN108018342A (zh) * 2017-12-04 2018-05-11 合肥艾迪康临床检验所有限公司 检测ar基因突变的引物和方法
CN109115742A (zh) * 2018-09-05 2019-01-01 中国农业科学院农业质量标准与检测技术研究所 一种抗雄激素效应的检测方法
CN109321569B (zh) * 2018-10-29 2022-04-12 迈杰转化医学研究(苏州)有限公司 一种引物探针组合物及其应用
KR102473989B1 (ko) 2018-11-28 2022-12-07 (주)바이오니아 안드로젠 수용체 특이적 서열을 포함하는 이중나선 올리고뉴클레오티드 구조체, 및 이를 포함하는 탈모 예방 및 발모용 조성물
JP2022549222A (ja) * 2019-09-23 2022-11-24 アキュター バイオテクノロジー インコーポレイテッド アンドロゲン受容体分解活性を有する新規尿素およびその使用
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WO2021110731A1 (en) * 2019-12-03 2021-06-10 Bayer Aktiengesellschaft Method for determining the response of prostate cancer patients to treatment with androgen receptor antagonists based on gene expression changes or super-enhancer protein-binding profiles
CN113533730B (zh) * 2021-07-23 2022-09-06 南方医科大学深圳医院 一种血浆外泌体标志物组合及其应用
WO2024001989A1 (en) * 2022-06-27 2024-01-04 Etern Biopharma (Shanghai) Co., Ltd. Compositions and methods for modulating molecules
CN117860773B (zh) * 2023-11-28 2024-07-16 四川大学华西医院 促进ar基因甲基化的药物及其在预防或治疗雄性激素脱发中的用途
CN117778322B (zh) * 2023-12-17 2025-02-07 苏州拓维生物技术有限公司 一种对恩杂鲁胺耐药的细胞系的筛选方法及其应用
CN121065176A (zh) * 2025-04-14 2025-12-05 羿美诚健(上海)生物医药有限公司 靶向雄激素受体的小核酸及其药物组合物和用途

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