JP2015531400A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015531400A5 JP2015531400A5 JP2015535845A JP2015535845A JP2015531400A5 JP 2015531400 A5 JP2015531400 A5 JP 2015531400A5 JP 2015535845 A JP2015535845 A JP 2015535845A JP 2015535845 A JP2015535845 A JP 2015535845A JP 2015531400 A5 JP2015531400 A5 JP 2015531400A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- oral dosage
- progesterone
- amount
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006186 oral dosage form Substances 0.000 claims 80
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims 64
- 229960003387 progesterone Drugs 0.000 claims 32
- 239000000186 progesterone Substances 0.000 claims 32
- 210000002966 serum Anatomy 0.000 claims 9
- DNXHEGUUPJUMQT-CBZIJGRNSA-N Estrone Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 DNXHEGUUPJUMQT-CBZIJGRNSA-N 0.000 claims 7
- 239000004094 surface-active agent Substances 0.000 claims 7
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 6
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 claims 6
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 6
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 6
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 6
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 6
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 6
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 6
- 229920000639 hydroxypropylmethylcellulose acetate succinate Polymers 0.000 claims 6
- 239000002552 dosage form Substances 0.000 claims 4
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 claims 3
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 3
- RSEPBGGWRJCQGY-RBRWEJTLSA-N Estradiol valerate Chemical compound C1CC2=CC(O)=CC=C2[C@@H]2[C@@H]1[C@@H]1CC[C@H](OC(=O)CCCC)[C@@]1(C)CC2 RSEPBGGWRJCQGY-RBRWEJTLSA-N 0.000 claims 3
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 claims 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims 3
- ZUAAPNNKRHMPKG-UHFFFAOYSA-N acetic acid;butanedioic acid;methanol;propane-1,2-diol Chemical compound OC.CC(O)=O.CC(O)CO.OC(=O)CCC(O)=O ZUAAPNNKRHMPKG-UHFFFAOYSA-N 0.000 claims 3
- 229960005309 estradiol Drugs 0.000 claims 3
- 229930182833 estradiol Natural products 0.000 claims 3
- 229960004766 estradiol valerate Drugs 0.000 claims 3
- 229960002568 ethinylestradiol Drugs 0.000 claims 3
- 230000011599 ovarian follicle development Effects 0.000 claims 3
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims 3
- 230000001225 therapeutic effect Effects 0.000 claims 3
- 229920002675 Polyoxyl Polymers 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 239000004359 castor oil Substances 0.000 claims 2
- 235000019438 castor oil Nutrition 0.000 claims 2
- 239000008367 deionised water Substances 0.000 claims 2
- 229910021641 deionized water Inorganic materials 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 238000010828 elution Methods 0.000 claims 2
- 230000001076 estrogenic effect Effects 0.000 claims 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 229940068196 placebo Drugs 0.000 claims 2
- 239000000902 placebo Substances 0.000 claims 2
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 239000003826 tablet Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- PROQIPRRNZUXQM-UHFFFAOYSA-N (16alpha,17betaOH)-Estra-1,3,5(10)-triene-3,16,17-triol Natural products OC1=CC=C2C3CCC(C)(C(C(O)C4)O)C4C3CCC2=C1 PROQIPRRNZUXQM-UHFFFAOYSA-N 0.000 claims 1
- JWMFYGXQPXQEEM-NUNROCCHSA-N 5β-pregnane Chemical compound C([C@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](CC)[C@@]2(C)CC1 JWMFYGXQPXQEEM-NUNROCCHSA-N 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 125000000129 anionic group Chemical group 0.000 claims 1
- 239000003945 anionic surfactant Substances 0.000 claims 1
- 239000003433 contraceptive agent Substances 0.000 claims 1
- 230000002254 contraceptive effect Effects 0.000 claims 1
- 239000008157 edible vegetable oil Substances 0.000 claims 1
- PROQIPRRNZUXQM-ZXXIGWHRSA-N estriol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H]([C@H](O)C4)O)[C@@H]4[C@@H]3CCC2=C1 PROQIPRRNZUXQM-ZXXIGWHRSA-N 0.000 claims 1
- 229960001348 estriol Drugs 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 239000013563 matrix tablet Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 230000027758 ovulation cycle Effects 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
- 229940068968 polysorbate 80 Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/644,929 US9375437B2 (en) | 2010-06-18 | 2012-10-04 | Progesterone containing oral dosage forms and kits |
| US13/644,929 | 2012-10-04 | ||
| PCT/US2013/063584 WO2014055954A1 (en) | 2012-10-04 | 2013-10-04 | Progesterone containing oral dosage forms and kits |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015531400A JP2015531400A (ja) | 2015-11-02 |
| JP2015531400A5 true JP2015531400A5 (enExample) | 2016-11-24 |
Family
ID=50435610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015535845A Pending JP2015531400A (ja) | 2012-10-04 | 2013-10-04 | プロゲステロン含有経口投与形態およびキット |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9375437B2 (enExample) |
| EP (1) | EP2903620A4 (enExample) |
| JP (1) | JP2015531400A (enExample) |
| AU (1) | AU2013326866A1 (enExample) |
| BR (1) | BR112015007642A2 (enExample) |
| CA (1) | CA2926073A1 (enExample) |
| MX (1) | MX2015004309A (enExample) |
| RU (1) | RU2015116932A (enExample) |
| WO (1) | WO2014055954A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060003002A1 (en) * | 2003-11-03 | 2006-01-05 | Lipocine, Inc. | Pharmaceutical compositions with synchronized solubilizer release |
| EP2682111A1 (en) | 2009-12-31 | 2014-01-08 | Differential Drug Development Associates LLC | Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols |
| US8951996B2 (en) | 2011-07-28 | 2015-02-10 | Lipocine Inc. | 17-hydroxyprogesterone ester-containing oral compositions and related methods |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| EP2782584B1 (en) | 2011-11-23 | 2021-06-09 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| ES2907284T3 (es) | 2013-03-15 | 2022-04-22 | Marius Pharmaceuticals Llc | Formulaciones de emulsión |
| AU2015264003A1 (en) | 2014-05-22 | 2016-11-17 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| ES3005883T3 (en) | 2015-06-22 | 2025-03-17 | Lipocine Inc | 17-hydroxyprogesterone ester-containing oral compositions and related methods |
| SI3313408T1 (sl) * | 2015-06-23 | 2024-04-30 | Laboratorios Leon Farma Sa | Kontraceptiv na osnovi drospirenona za pacientko s prekomerno težo |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| WO2017105512A1 (en) | 2015-12-18 | 2017-06-22 | Proinvet Innovations S.A. | Formulations and methods for controlling the reproductive cycle and ovulation |
| US20170281647A1 (en) * | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| JP6758145B2 (ja) * | 2016-10-05 | 2020-09-23 | 株式会社ディーエイチシー | 油脂組成物及びカプセル剤 |
| US10285998B1 (en) | 2018-04-04 | 2019-05-14 | The Menopause Method, Inc. | Composition and method to aid in hormone replacement therapy |
| US12403146B2 (en) | 2019-10-30 | 2025-09-02 | Marius Pharmaceuticals, Inc. | Preferred oral testosterone undecanoate therapy to achieve testosterone replacement treatment |
| US12208103B1 (en) | 2021-05-07 | 2025-01-28 | Lipocine Inc. | Compositions and methods for treating CNS disorders |
| US11969434B1 (en) | 2022-08-29 | 2024-04-30 | Lipocine Inc. | Oral allopregnanolone compositions and methods of use |
| US11337987B1 (en) | 2021-05-07 | 2022-05-24 | Lipocine Inc. | Compositions and methods for treating central nervous system disorders |
| CN116077416B (zh) * | 2021-11-05 | 2024-12-06 | 深圳埃格林医药有限公司 | 一种包含孕激素的口服制剂及制备方法和应用 |
| US12186327B2 (en) | 2022-08-29 | 2025-01-07 | Lipocine Inc. | Oral allopregnanolone compositions and methods of use |
| WO2025178616A1 (en) * | 2024-02-21 | 2025-08-28 | Lipocine, Inc. | Oral allopregnanolone compositions and methods of use |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3164520A (en) | 1962-10-29 | 1965-01-05 | Olin Mathieson | Injectable steroid compositions containing at least 75% benzyl benzoate |
| FR2408345A1 (fr) | 1976-11-30 | 1979-06-08 | Besins Jean Louis | Nouvelle composition a action anti-conceptionnelle |
| US4230702A (en) | 1978-01-09 | 1980-10-28 | Kali-Chemie Pharma Gmbh | Readily enterally absorbable pharmaceutical compositions of per se poorly enterally absorbable pharmacologically active agents |
| US4439432A (en) | 1982-03-22 | 1984-03-27 | Peat Raymond F | Treatment of progesterone deficiency and related conditions with a stable composition of progesterone and tocopherols |
| US5140021A (en) | 1986-04-16 | 1992-08-18 | Genesis Systems Corporation | Method and dosage form for treatment of premenstrual syndrome |
| GB8730011D0 (en) | 1987-12-23 | 1988-02-03 | Smithkline Dauelsberg | Pharmaceutical compositions |
| WO1990008537A1 (en) | 1989-02-06 | 1990-08-09 | Abbott Laboratories | Pharmaceutical compositions for oral administration |
| IT1252867B (it) | 1991-12-31 | 1995-06-28 | Gentili Ist Spa | Composizioni farmaceutiche contenenti progesterone ad elevata biodisponibilita' |
| DK95093D0 (da) | 1993-08-20 | 1993-08-20 | Novo Nordisk As | Farmaceutisk formulering indeholdende et hormon |
| US5543150A (en) | 1993-09-15 | 1996-08-06 | Columbia Laboratories, Inc. | Method of progesterone delivery and affect thereof |
| GB9405304D0 (en) | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
| US5633011A (en) | 1994-08-04 | 1997-05-27 | Alza Corporation | Progesterone replacement therapy |
| CA2198099C (en) | 1994-08-23 | 2001-01-16 | Adam Milan | Use of tasteless, hydrolysed collagen and agent containing the same |
| DE19718012C1 (de) | 1997-04-29 | 1998-10-08 | Jenapharm Gmbh | Verfahren zur Herstellung peroral anwendbarer fester Arzneiformen mit gesteuerter Wirkstoffabgabe |
| DE19739916C2 (de) | 1997-09-11 | 2001-09-13 | Hesch Rolf Dieter | Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen |
| FR2772617B1 (fr) | 1997-12-19 | 2001-03-09 | Besins Iscovesco Lab | Comprime de progesterone et son procede de preparation |
| FR2775599B1 (fr) | 1998-03-09 | 2001-08-17 | Besins Iscovesco Lab | Composition pharmaceutique a base de progesterone naturelle de synthese et d'oestradiol et son procede de preparation |
| US6602521B1 (en) | 1998-09-29 | 2003-08-05 | Impax Pharmaceuticals, Inc. | Multiplex drug delivery system suitable for oral administration |
| US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US7374779B2 (en) | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| GB9907715D0 (en) | 1999-04-01 | 1999-05-26 | Scherer Corp R P | Pharmaceutical compositions |
| US20030236236A1 (en) | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
| US20020131988A1 (en) | 1999-12-16 | 2002-09-19 | Foster Todd P. | Pharmaceutical implant containing immediate-release and sustained-release components and method of administration |
| US6544553B1 (en) | 1999-12-28 | 2003-04-08 | Watson Pharmaceuticals, Inc. | Dosage forms and methods for oral delivery of progesterone |
| US20040022862A1 (en) | 2000-12-22 | 2004-02-05 | Kipp James E. | Method for preparing small particles |
| FR2818905A1 (fr) | 2000-12-28 | 2002-07-05 | Cll Pharma | Compositions pharmaceutiques colloidales micellaires renfermant un principe actif lipophile |
| FR2821555B1 (fr) | 2001-03-01 | 2003-05-16 | Besins Int Lab | Progestatif co-micronise avec un tensioactif, composition pharmaceutique le comprenant, leurs procedes de fabrication et leurs utilisations |
| FR2832065B1 (fr) | 2001-11-13 | 2004-11-05 | Besins Int Belgique | Composition pharmaceutique a base de progesterone micronisee son procede de preparation et ses utilisations |
| CN1622810A (zh) | 2002-03-14 | 2005-06-01 | 华生制药公司 | 孕酮口服药物传输系统 |
| US8216609B2 (en) * | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
| CN1231210C (zh) | 2002-08-20 | 2005-12-14 | 杭州容立医药科技有限公司 | 黄体酮胶囊组合物及其制备方法 |
| WO2004022065A1 (en) * | 2002-09-05 | 2004-03-18 | Pantarhei Bioscience B.V. | Pharmaceutical application of 15- or 16- substituted testosterone analogues |
| JP2004155780A (ja) | 2002-10-16 | 2004-06-03 | Taisho Pharmaceut Co Ltd | 生活習慣病改善剤組成物 |
| AU2003299659A1 (en) | 2002-12-13 | 2004-07-09 | Durect Corporation | Oral drug delivery system comprising high viscosity liquid carrier materials |
| CN1282459C (zh) | 2002-12-24 | 2006-11-01 | 上海医药工业研究院 | 黄体酮胶丸及制备方法 |
| ATE553378T1 (de) | 2003-02-06 | 2012-04-15 | Hologic Inc | Screening und behandlungsverfahren zur vorbeugung von frühgeburten |
| GB0305941D0 (en) | 2003-03-14 | 2003-04-23 | Camurus Ab | Composition |
| CN1299686C (zh) | 2003-04-03 | 2007-02-14 | 上海医药工业研究院 | 黄体酮半固体骨架制剂的组合物 |
| CN1623550A (zh) | 2003-12-04 | 2005-06-08 | 张伟 | 己酸羟孕酮口服制剂和用途 |
| GT200500186A (es) | 2004-07-07 | 2006-03-02 | Regimenes anticonceptivos con antagonistas del receptor de progesterona y kits | |
| US7473687B2 (en) * | 2005-03-24 | 2009-01-06 | Emory University | Methods for the treatment of a traumatic central nervous system injury |
| EA015155B1 (ru) | 2005-05-26 | 2011-06-30 | Тева Вуменс Хелс, Инк. | Дозированные формы для перорального применения, содержащие прогестерон, и способы их изготовления и использования |
| US8828981B2 (en) | 2007-02-06 | 2014-09-09 | George Creasy | Progesterone for the treatment or prevention of spontaneous preterm birth |
| AU2008303129B2 (en) | 2007-09-25 | 2013-08-01 | Formulex Pharma Innovations Ltd. | Compositions comprising lipophilic active compounds and method for their preparation |
| EP2219554A4 (en) | 2007-11-29 | 2011-05-25 | Gregg A Jackson | PROGESTER-CONTAINING COMPOSITIONS AND DEVICES |
| CN101960931B (zh) * | 2008-04-10 | 2012-09-05 | 松下电器产业株式会社 | 流焊装置和流焊方法 |
| WO2010117873A2 (en) | 2009-04-06 | 2010-10-14 | Banner Pharmacaps, Inc. | Progesterone solutions for increased bioavailability |
| AU2010313447A1 (en) | 2009-10-29 | 2012-05-31 | The Trustees Of The University Of Pennsylvania | Method of predicting risk of preterm birth |
| WO2011079047A1 (en) | 2009-12-23 | 2011-06-30 | Drugtech Corporation | Methods for reducing the occurrence of preterm delivery and other pregnancy-related conditions |
| CA2789238C (en) | 2010-03-09 | 2020-05-12 | Dignity Health | Methods for inhibiting preterm labor and uterine contractility disorders and preventing cervical ripening |
| US20110312928A1 (en) * | 2010-06-18 | 2011-12-22 | Lipocine Inc. | Progesterone Containing Oral Dosage Forms and Related Methods |
| US20110312927A1 (en) * | 2010-06-18 | 2011-12-22 | Satish Kumar Nachaegari | Progesterone Containing Oral Dosage Forms and Related Methods |
| US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| US8951996B2 (en) | 2011-07-28 | 2015-02-10 | Lipocine Inc. | 17-hydroxyprogesterone ester-containing oral compositions and related methods |
-
2012
- 2012-10-04 US US13/644,929 patent/US9375437B2/en active Active
-
2013
- 2013-10-04 BR BR112015007642A patent/BR112015007642A2/pt not_active Application Discontinuation
- 2013-10-04 CA CA2926073A patent/CA2926073A1/en not_active Abandoned
- 2013-10-04 RU RU2015116932A patent/RU2015116932A/ru not_active Application Discontinuation
- 2013-10-04 MX MX2015004309A patent/MX2015004309A/es unknown
- 2013-10-04 WO PCT/US2013/063584 patent/WO2014055954A1/en not_active Ceased
- 2013-10-04 EP EP13843181.2A patent/EP2903620A4/en not_active Withdrawn
- 2013-10-04 JP JP2015535845A patent/JP2015531400A/ja active Pending
- 2013-10-04 AU AU2013326866A patent/AU2013326866A1/en not_active Abandoned
-
2016
- 2016-04-05 US US15/090,866 patent/US20160213687A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015531400A5 (enExample) | ||
| RU2015116932A (ru) | Пероральные лекарственные формы и наборы, содержащие прогестерон | |
| US5422119A (en) | Transdermal hormone replacement therapy | |
| US8507465B2 (en) | Antiemetic-oral contraceptive combination | |
| JP2013529665A5 (enExample) | ||
| RS50262B (sr) | Farmaceutska kombinacija etinilestradiola i drospirenona za primenu kao kontraceptivnog sredstva | |
| WO2011160136A3 (en) | Progesterone containing oral dosage forms and related methods | |
| JP2010180236A5 (enExample) | ||
| WO2013022783A3 (en) | Progesterone containing oral dosage forms and related methods | |
| JP2010503632A (ja) | 経口改良放出製剤 | |
| TW200831107A (en) | Methods of hormonal treatment utilizing ascending-dose extended cycle regimens | |
| BG106915A (bg) | Дрозпиренон за хормонзаместваща терапия | |
| TW200815019A (en) | Extended step-down estrogen regimen | |
| KR20110045065A (ko) | 월경 억제, 피임 및 호르몬 대체 요법을 위한 약제 및 이를 투여하는 방법 | |
| RU2011146058A (ru) | Способ контрацепции, используемый по мере необходимости | |
| JP2004520375A (ja) | エストロゲン補充療法を受けている女性のホルモン不足の治療方法 | |
| JP2009501747A (ja) | トリメゲストンによる経口避妊 | |
| JP2005516913A5 (enExample) | ||
| Friend | Development of controlled release systems over the past 50 years in the area of contraception | |
| RU2482853C2 (ru) | Фармацевтическая композиция, способ ее получения и многофазный фармацевтический препарат для ингибирования овуляции у млекопитающего | |
| LaGuardia et al. | Suppression of estrogen-withdrawal headache with extended transdermal contraception | |
| JP2009512658A5 (enExample) | ||
| JP2002505280A (ja) | 一過性熱感を軽減するための塩酸フルオキセチン | |
| CN101189015A (zh) | 延长的雌激素定量给药避孕疗法 | |
| JP2011507853A5 (enExample) |