|
US4356170A
(en)
|
1981-05-27 |
1982-10-26 |
Canadian Patents & Development Ltd. |
Immunogenic polysaccharide-protein conjugates
|
|
SE8205892D0
(sv)
|
1982-10-18 |
1982-10-18 |
Bror Morein |
Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
|
|
US5916588A
(en)
|
1984-04-12 |
1999-06-29 |
The Liposome Company, Inc. |
Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
|
|
US6090406A
(en)
|
1984-04-12 |
2000-07-18 |
The Liposome Company, Inc. |
Potentiation of immune responses with liposomal adjuvants
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
AU627226B2
(en)
|
1988-08-25 |
1992-08-20 |
Liposome Company, Inc., The |
Influenza vaccine and novel adjuvants
|
|
DE3841091A1
(de)
|
1988-12-07 |
1990-06-13 |
Behringwerke Ag |
Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung
|
|
ES2055785T3
(es)
|
1989-01-17 |
1994-09-01 |
Eniricerche Spa |
Peptidos sinteticos y su uso como vehiculos universales para la preparacion de conjugados inmunogenos aptos para el desarrollo de vacunas sinteticas.
|
|
HU212924B
(en)
|
1989-05-25 |
1996-12-30 |
Chiron Corp |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
US5334379A
(en)
|
1989-07-14 |
1994-08-02 |
American Cyanamid Company |
Cytokine and hormone carriers for conjugate vaccines
|
|
IT1237764B
(it)
|
1989-11-10 |
1993-06-17 |
Eniricerche Spa |
Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
|
|
SE466259B
(sv)
|
1990-05-31 |
1992-01-20 |
Arne Forsgren |
Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
|
|
IL98715A0
(en)
|
1990-08-13 |
1992-07-15 |
American Cyanamid Co |
Filamentous hemaglutinin of bodetella pertussis as a carrier molecule for conjugate vaccines
|
|
US5153312A
(en)
|
1990-09-28 |
1992-10-06 |
American Cyanamid Company |
Oligosaccharide conjugate vaccines
|
|
IT1262896B
(it)
|
1992-03-06 |
1996-07-22 |
|
Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
|
|
UA40597C2
(uk)
|
1992-06-25 |
2001-08-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Вакцинна композиція,спосіб лікування ссавців, що страждають або сприйнятливі до інфекції, спосіб лікування ссавців, що страждають на рак, спосіб одержання вакцинної композиції, композиція ад'ювантів
|
|
IL102687A
(en)
|
1992-07-30 |
1997-06-10 |
Yeda Res & Dev |
Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
|
|
ZA937034B
(en)
|
1992-09-24 |
1995-06-23 |
Brigham & Womens Hospital |
Group B streptococcus type II and type V polysaccharide-protein conjugate vaccines
|
|
EP0667787B1
(en)
|
1992-09-24 |
2001-07-18 |
Brigham And Women's Hospital |
Group b streptococcus type ii and type v polysaccharide-protein conjugate vaccines
|
|
EP0616034B1
(en)
|
1993-03-05 |
2004-10-20 |
Wyeth Holdings Corporation |
Plasmid for production of CRM protein and diphtheria toxin
|
|
EP1175912A1
(en)
|
1993-03-23 |
2002-01-30 |
SmithKline Beecham Biologics SA |
Vaccine compositions containing 3-O deacylated monophosphoryl lipid A
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
|
US6429199B1
(en)
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
AUPM873294A0
(en)
|
1994-10-12 |
1994-11-03 |
Csl Limited |
Saponin preparations and use thereof in iscoms
|
|
UA56132C2
(uk)
|
1995-04-25 |
2003-05-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
|
|
US6284884B1
(en)
|
1995-06-07 |
2001-09-04 |
North American Vaccine, Inc. |
Antigenic group B streptococcus type II and type III polysaccharide fragments having a 2,5-anhydro-D-mannose terminal structure and conjugate vaccine thereof
|
|
JP4108746B2
(ja)
*
|
1995-06-07 |
2008-06-25 |
ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
ヘルパーウイルスを含まないａａｖ産生
|
|
DE69615362T3
(de)
|
1995-06-07 |
2006-07-20 |
Smithkline Beecham Biologicals S.A. |
Impfstoff mit einem polysaccharidantigen-trägerprotein-konjugat und einem trägerprotein
|
|
GB9513261D0
(en)
|
1995-06-29 |
1995-09-06 |
Smithkline Beecham Biolog |
Vaccines
|
|
WO1998040100A1
(en)
|
1997-03-10 |
1998-09-17 |
Ottawa Civic Loeb Research Institute |
USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE AS AN ADJUVANT
|
|
US6426074B1
(en)
*
|
1997-03-19 |
2002-07-30 |
The Brigham And Women's Hospital Inc. |
Group B Streptococcus vaccine
|
|
US6818222B1
(en)
|
1997-03-21 |
2004-11-16 |
Chiron Corporation |
Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
|
|
US6299881B1
(en)
|
1997-03-24 |
2001-10-09 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
|
|
CA2284606A1
(en)
|
1997-03-26 |
1998-10-01 |
Brigham And Women's Hospital, Inc. |
Method for generating saccharide fragments
|
|
FR2763244B1
(fr)
|
1997-05-14 |
2003-08-01 |
Pasteur Merieux Serums Vacc |
Composition vaccinale multivalente a porteur mixte
|
|
GB9712347D0
(en)
|
1997-06-14 |
1997-08-13 |
Smithkline Beecham Biolog |
Vaccine
|
|
GB9713156D0
(en)
|
1997-06-20 |
1997-08-27 |
Microbiological Res Authority |
Vaccines
|
|
DE69815692T2
(de)
|
1997-09-05 |
2004-04-29 |
Glaxosmithkline Biologicals S.A. |
Öl in wasser emulsionen mit saponinen
|
|
EP1900818A3
(en)
|
1997-11-06 |
2008-06-11 |
Novartis Vaccines and Diagnostics S.r.l. |
Neisserial antigens
|
|
GB9725084D0
(en)
|
1997-11-28 |
1998-01-28 |
Medeva Europ Ltd |
Vaccine compositions
|
|
SG152917A1
(en)
|
1998-01-14 |
2009-06-29 |
Chiron Srl |
Neisseria meningitidis antigens
|
|
EP1053015A2
(en)
|
1998-02-12 |
2000-11-22 |
American Cyanamid Company |
Pneumococcal and meningococcal vaccines formulated with interleukin-12
|
|
US7018637B2
(en)
|
1998-02-23 |
2006-03-28 |
Aventis Pasteur, Inc |
Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
|
|
US6303114B1
(en)
|
1998-03-05 |
2001-10-16 |
The Medical College Of Ohio |
IL-12 enhancement of immune responses to T-independent antigens
|
|
AU746163B2
(en)
|
1998-04-09 |
2002-04-18 |
Smithkline Beecham Biologicals (Sa) |
Adjuvant compositions
|
|
EP2261350A3
(en)
|
1998-05-01 |
2012-01-04 |
Novartis Vaccines and Diagnostics, Inc. |
Neisseria meningitidis antigens and compositions
|
|
US6562798B1
(en)
|
1998-06-05 |
2003-05-13 |
Dynavax Technologies Corp. |
Immunostimulatory oligonucleotides with modified bases and methods of use thereof
|
|
GB9817052D0
(en)
|
1998-08-05 |
1998-09-30 |
Smithkline Beecham Biolog |
Vaccine
|
|
MXPA01003557A
(es)
|
1998-10-09 |
2004-04-05 |
Chiron Corp |
Secuencias genomicas de neisseria y metodos para su uso.
|
|
CA2773698C
(en)
|
1998-10-16 |
2015-05-19 |
Glaxosmithkline Biologicals S.A. |
Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof
|
|
AU1626199A
(en)
|
1998-12-04 |
2000-06-26 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
A vi-repa conjugate vaccine for immunization against salmonella typhi
|
|
US6146902A
(en)
|
1998-12-29 |
2000-11-14 |
Aventis Pasteur, Inc. |
Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
|
|
MXPA01007895A
(es)
|
1999-02-03 |
2003-07-21 |
Biosante Pharmaceuticals Inc |
Particulas terapeuticas de fosfato de calcio, metodos de manufactura y usos.
|
|
EP1034792A1
(en)
|
1999-03-11 |
2000-09-13 |
Pasteur Merieux Serums Et Vaccins |
Intranasal delivery of pneumococcal polysaccharide vaccines
|
|
MY125202A
(en)
|
1999-03-19 |
2006-07-31 |
Smithkline Beecham Biologicals S A |
Vaccine
|
|
FR2791895B1
(fr)
|
1999-03-23 |
2001-06-15 |
Pasteur Merieux Serums Vacc |
Utilisation de trehalose pour stabiliser un vaccin liquide
|
|
WO2000061761A2
(en)
|
1999-04-09 |
2000-10-19 |
Techlab, Inc. |
Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines
|
|
IL148672A0
(en)
|
1999-09-24 |
2002-09-12 |
Smithkline Beecham Biolog |
Use of combination of polyxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines
|
|
HK1046861A1
(zh)
|
1999-09-24 |
2003-01-30 |
Smithkline Beecham Biologicals S.A. |
包括聚氧乙烯烷基酯或者醚以及至少一種非離子表面活性劑的佐劑
|
|
JP4948731B2
(ja)
|
1999-12-02 |
2012-06-06 |
ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド |
凍結乾燥の際に生物学的分子を安定化するための組成物および方法
|
|
ATE476988T1
(de)
|
2000-01-17 |
2010-08-15 |
Novartis Vaccines & Diagnostic |
Membranvesikel (omv) impfstoff, der n. meningitidis serogruppe b membranproteine enthält
|
|
AU3108001A
(en)
|
2000-01-20 |
2001-12-24 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory nucleic acids for inducing a th2 immune response
|
|
GB0007432D0
(en)
|
2000-03-27 |
2000-05-17 |
Microbiological Res Authority |
Proteins for use as carriers in conjugate vaccines
|
|
GB0108364D0
(en)
|
2001-04-03 |
2001-05-23 |
Glaxosmithkline Biolog Sa |
Vaccine composition
|
|
JP2004509970A
(ja)
|
2000-09-26 |
2004-04-02 |
ハイブリドン・インコーポレイテッド |
位置的化学変化による免疫刺激オリゴヌクレオチドアナログの免疫刺激活性の調節
|
|
ES2330083T3
(es)
|
2000-10-27 |
2009-12-04 |
Novartis Vaccines And Diagnostics S.R.L. |
Acidos nucleicos y proteinas de estreptococos de los grupos a y b.
|
|
WO2002091998A2
(en)
|
2001-05-11 |
2002-11-21 |
Aventis Pasteur, Inc. |
Novel meningitis conjugate vaccine
|
|
EP1409013B1
(en)
|
2001-07-26 |
2009-11-18 |
Novartis Vaccines and Diagnostics S.r.l. |
Vaccines comprising aluminium adjuvants and histidine
|
|
CN1599623B
(zh)
|
2001-09-14 |
2011-05-11 |
赛托斯生物技术公司 |
免疫刺激物向病毒样颗粒内的包装:制备方法与用途
|
|
WO2003024480A2
(en)
|
2001-09-14 |
2003-03-27 |
Cytos Biotechnology Ag |
In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles
|
|
WO2003035836A2
(en)
|
2001-10-24 |
2003-05-01 |
Hybridon Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
|
|
GB0210128D0
(en)
|
2002-05-02 |
2002-06-12 |
Chiron Spa |
Nucleic acids and proteins from streptococcus groups A & B
|
|
AU2003257003A1
(en)
|
2002-07-30 |
2004-02-16 |
Baxter Healthcare S.A. |
Chimeric multivalent polysaccharide conjugate vaccines
|
|
US20070053924A1
(en)
|
2002-08-26 |
2007-03-08 |
Herve Tettelin |
Conserved and specific streptococcal genomes
|
|
PT1551357E
(pt)
|
2002-09-13 |
2014-10-10 |
Novartis Vaccines & Diagnostic |
Vacina contra os estreptococos do grupo b
|
|
US7521062B2
(en)
|
2002-12-27 |
2009-04-21 |
Novartis Vaccines & Diagnostics, Inc. |
Thiosemicarbazones as anti-virals and immunopotentiators
|
|
ES2391770T3
(es)
|
2003-01-21 |
2012-11-29 |
Novartis Vaccines And Diagnostics, Inc. |
Uso de compuestos de triptantrina para la potenciación inmune
|
|
KR101206544B1
(ko)
|
2003-06-23 |
2012-11-30 |
박스터 헬쓰케어 에스.에이. |
백신용 담체 단백질
|
|
GB0323103D0
(en)
|
2003-10-02 |
2003-11-05 |
Chiron Srl |
De-acetylated saccharides
|
|
GB0411387D0
(en)
|
2004-05-21 |
2004-06-23 |
Chiron Srl |
Analysis of saccharide length
|
|
MX2007005202A
(es)
|
2004-11-01 |
2007-07-09 |
Brigham & Womens Hospital |
Polisacaridos de estreptococo modificados y usos de los mismos.
|
|
EP1828231A2
(en)
|
2004-12-22 |
2007-09-05 |
Novartis Vaccines and Diagnostics, Inc. |
Group b streptococcus
|
|
GB0502096D0
(en)
*
|
2005-02-01 |
2005-03-09 |
Chiron Srl |
Purification of streptococcal capsular polysaccharide
|
|
GB0502095D0
(en)
*
|
2005-02-01 |
2005-03-09 |
Chiron Srl |
Conjugation of streptococcal capsular saccharides
|
|
CA2636983A1
(en)
|
2006-01-13 |
2007-07-26 |
Baxter International Inc. |
Method for purifying polysaccharides
|
|
US20100150943A1
(en)
|
2006-07-26 |
2010-06-17 |
Novartis Ag |
Immunogenic compositions for gram positive bacteria
|
|
WO2008028957A2
(en)
|
2006-09-07 |
2008-03-13 |
Glaxosmithkline Biologicals S.A. |
Vaccine
|
|
ITBO20060890A1
(it)
|
2006-12-28 |
2008-06-29 |
Bg Informatica S R L |
Dispositivo per la valutazione della sensibilita' cutanea alle vibrazioni di un soggetto, ed in particolare di un soggetto diabetico
|
|
ES2677353T3
(es)
|
2007-03-23 |
2018-08-01 |
Wyeth Llc |
Procedimiento abreviado de purificación para la producción de polisacáridos capsulares de Streptococcus pneumoniae
|
|
HRP20160995T1
(hr)
|
2007-04-16 |
2016-10-21 |
Minervax Aps |
Cjepivo fuzijskog proteina
|
|
GB0713880D0
(en)
|
2007-07-17 |
2007-08-29 |
Novartis Ag |
Conjugate purification
|
|
GB0818453D0
(en)
|
2008-10-08 |
2008-11-12 |
Novartis Ag |
Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
|
|
GB0802503D0
(en)
|
2008-02-11 |
2008-03-19 |
Novartis Ag |
Hybrid polypeptide
|
|
GB201101665D0
(en)
|
2011-01-31 |
2011-03-16 |
Novartis Ag |
Immunogenic compositions
|
|
GB201121301D0
(en)
|
2011-12-12 |
2012-01-25 |
Novartis Ag |
Method
|
|
ES2690526T3
(es)
|
2012-10-03 |
2018-11-21 |
Glaxosmithkline Biologicals S.A. |
Composiciones inmunogénicas
|