JP2015509963A5 - - Google Patents

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Publication number
JP2015509963A5
JP2015509963A5 JP2014560384A JP2014560384A JP2015509963A5 JP 2015509963 A5 JP2015509963 A5 JP 2015509963A5 JP 2014560384 A JP2014560384 A JP 2014560384A JP 2014560384 A JP2014560384 A JP 2014560384A JP 2015509963 A5 JP2015509963 A5 JP 2015509963A5
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JP
Japan
Prior art keywords
composition according
motomeko
toxoid
composition
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014560384A
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English (en)
Japanese (ja)
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JP2015509963A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2013/054674 external-priority patent/WO2013132043A1/en
Publication of JP2015509963A publication Critical patent/JP2015509963A/ja
Publication of JP2015509963A5 publication Critical patent/JP2015509963A5/ja
Pending legal-status Critical Current

Links

JP2014560384A 2012-03-08 2013-03-08 Ｔｌｒ４アゴニストを含む混合ワクチン Pending JP2015509963A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261608409P 2012-03-08 2012-03-08
US61/608,409 2012-03-08
US201261697745P 2012-09-06 2012-09-06
US61/697,745 2012-09-06
PCT/EP2013/054674 WO2013132043A1 (en) 2012-03-08 2013-03-08 Combination vaccines with tlr4 agonists

Publications (2)

Publication Number Publication Date
JP2015509963A JP2015509963A (ja) 2015-04-02
JP2015509963A5 true JP2015509963A5 (enExample) 2016-04-28

Family

ID=47844315

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014560384A Pending JP2015509963A (ja) 2012-03-08 2013-03-08 Ｔｌｒ４アゴニストを含む混合ワクチン

Country Status (5)

Country Link
US (1) US20150125486A1 (enExample)
EP (1) EP2822584A1 (enExample)
JP (1) JP2015509963A (enExample)
CN (1) CN104159603A (enExample)
WO (1) WO2013132043A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0822633D0 (en) * 2008-12-11 2009-01-21 Novartis Ag Formulation
US20140363461A1 (en) * 2011-09-01 2014-12-11 Fabio Bagnoli Adjuvanted formulations of staphylococcus aureus antigens
KR20200083571A (ko) * 2017-11-03 2020-07-08 다케다 백신즈 인코포레이티드 지카 바이러스를 비활성화시키기 위한, 그리고 비활성화의 완결도를 결정하기 위한 방법
JP7443233B2 (ja) 2017-11-30 2024-03-05 タケダ ワクチン，インコーポレイテッド ジカウイルスを不活性化する方法及び関連する方法
SG11202007688YA (en) 2018-02-12 2020-09-29 Inimmune Corp Toll-like receptor ligands
JP7605739B2 (ja) * 2018-12-05 2024-12-24 サノフィ パスツール インコーポレイテッド 百日咳ブースターワクチン
CN114206378B (zh) * 2019-05-23 2024-10-25 蒙大拿大学 基于tlr受体配体的疫苗佐剂

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057685A (en) 1972-02-02 1977-11-08 Abbott Laboratories Chemically modified endotoxin immunizing agent
US4673574A (en) 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
US4459286A (en) 1983-01-31 1984-07-10 Merck & Co., Inc. Coupled H. influenzae type B vaccine
US4663160A (en) 1983-03-14 1987-05-05 Miles Laboratories, Inc. Vaccines for gram-negative bacteria
US4761283A (en) 1983-07-05 1988-08-02 The University Of Rochester Immunogenic conjugates
US4808700A (en) 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
IT1187753B (it) 1985-07-05 1987-12-23 Sclavo Spa Coniugati glicoproteici ad attivita' immunogenica trivalente
US5204098A (en) 1988-02-16 1993-04-20 The United States Of America As Represented By The Department Of Health And Human Services Polysaccharide-protein conjugates
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
NL8802046A (nl) 1988-08-18 1990-03-16 Gen Electric Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen.
ES2055785T3 (es) 1989-01-17 1994-09-01 Eniricerche Spa Peptidos sinteticos y su uso como vehiculos universales para la preparacion de conjugados inmunogenos aptos para el desarrollo de vacunas sinteticas.
US5334379A (en) 1989-07-14 1994-08-02 American Cyanamid Company Cytokine and hormone carriers for conjugate vaccines
IT1237764B (it) 1989-11-10 1993-06-17 Eniricerche Spa Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
SE466259B (sv) 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
IL98715A0 (en) 1990-08-13 1992-07-15 American Cyanamid Co Filamentous hemaglutinin of bodetella pertussis as a carrier molecule for conjugate vaccines
US5153312A (en) 1990-09-28 1992-10-06 American Cyanamid Company Oligosaccharide conjugate vaccines
IT1262896B (it) 1992-03-06 1996-07-22 Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
ATE444079T1 (de) * 1992-05-23 2009-10-15 Glaxosmithkline Biolog Sa Kombinierte impfstoffe, die hepatitis b oberfläche antigen und andere antigenen enthalten
IL102687A (en) 1992-07-30 1997-06-10 Yeda Res & Dev Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
US5425946A (en) 1992-08-31 1995-06-20 North American Vaccine, Inc. Vaccines against group C Neisseria meningitidis
EP0658118B1 (en) 1992-08-31 2002-01-23 Baxter Healthcare S.A. Vaccines against group c neisseria meningitidis
EP1175912A1 (en) 1993-03-23 2002-01-30 SmithKline Beecham Biologics SA Vaccine compositions containing 3-O deacylated monophosphoryl lipid A
DE69615362T3 (de) 1995-06-07 2006-07-20 Smithkline Beecham Biologicals S.A. Impfstoff mit einem polysaccharidantigen-trägerprotein-konjugat und einem trägerprotein
US6299881B1 (en) 1997-03-24 2001-10-09 Henry M. Jackson Foundation For The Advancement Of Military Medicine Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
GB9713156D0 (en) 1997-06-20 1997-08-27 Microbiological Res Authority Vaccines
GB9806456D0 (en) * 1998-03-25 1998-05-27 Smithkline Beecham Biolog Vaccine composition
EP2261350A3 (en) 1998-05-01 2012-01-04 Novartis Vaccines and Diagnostics, Inc. Neisseria meningitidis antigens and compositions
CN1263510C (zh) 1998-08-19 2006-07-12 巴克斯特健康护理股份有限公司 多糖－蛋白质缀合物或寡糖－蛋白质缀合物、其制备方法及其应用
US20030130212A1 (en) 1999-01-14 2003-07-10 Rossignol Daniel P. Administration of an anti-endotoxin drug by intravenous infusion
US6551600B2 (en) 1999-02-01 2003-04-22 Eisai Co., Ltd. Immunological adjuvant compounds compositions and methods of use thereof
MY125202A (en) 1999-03-19 2006-07-31 Smithkline Beecham Biologicals S A Vaccine
WO2000061761A2 (en) 1999-04-09 2000-10-19 Techlab, Inc. Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines
JP4948731B2 (ja) 1999-12-02 2012-06-06 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 凍結乾燥の際に生物学的分子を安定化するための組成物および方法
GB0007432D0 (en) 2000-03-27 2000-05-17 Microbiological Res Authority Proteins for use as carriers in conjugate vaccines
EP2277541A1 (en) * 2000-06-29 2011-01-26 SmithKline Beecham Biologicals S.A. Multivalent vaccine composition
GB0108364D0 (en) * 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
EP1355673B1 (en) 2001-01-23 2012-05-30 Sanofi Pasteur Inc. Multivalent meningococcal polysaccharide-protein conjugate vaccine
WO2002091998A2 (en) 2001-05-11 2002-11-21 Aventis Pasteur, Inc. Novel meningitis conjugate vaccine
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
GB0202901D0 (en) 2002-02-07 2002-03-27 Glaxosmithkline Biolog Sa Novel vaccine
BR0308768A (pt) 2002-03-26 2005-02-15 Chiron Srl Sacarìdeos modificados possuindo estabilidade melhorada em água
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
AU2004251734B2 (en) 2003-06-23 2010-11-04 Baxalta GmbH Vaccines against group Y neisseria meningitidis and meningococcal combinations thereof
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
EP2425856A1 (en) 2005-04-08 2012-03-07 Wyeth LLC Multivalent pneumococcal polysaccharide-protein conjugate composition
MX2007012337A (es) 2005-04-08 2007-11-21 Wyeth Corp Separacion de contaminantes de polisacarido de streptococcus pneumoniae por manipulacion de ph.
US20070184072A1 (en) 2005-04-08 2007-08-09 Wyeth Multivalent pneumococcal polysaccharide-protein conjugate composition
US7955605B2 (en) 2005-04-08 2011-06-07 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
WO2007000341A2 (en) 2005-06-27 2007-01-04 Glaxosmithkline Biologicals S.A. Immunogenic composition
WO2007053455A2 (en) 2005-10-28 2007-05-10 Vaxinnate Corporation Polypeptide ligans for toll-like receptor 4 (tlr4)
GB0522765D0 (en) 2005-11-08 2005-12-14 Chiron Srl Combination vaccine manufacture
HUE032903T2 (hu) 2005-12-22 2017-11-28 Glaxosmithkline Biologicals Sa Streptococcus pneumoniae kapszulárispoliszacharid-konjugátumok
GB0616306D0 (en) * 2006-08-16 2006-09-27 Novartis Ag Vaccines
WO2008028957A2 (en) 2006-09-07 2008-03-13 Glaxosmithkline Biologicals S.A. Vaccine
RU2460539C2 (ru) 2006-10-10 2012-09-10 Вайет СПОСОБ ОЧИСТКИ ПОЛИСАХАРИДОВ Streptococcus pneumoniae 3 ТИПА (ВАРИАНТЫ)
CN105999275A (zh) 2010-09-01 2016-10-12 诺华有限公司 免疫增强剂吸附不溶性金属离子
ES2681698T3 (es) * 2011-03-02 2018-09-14 Glaxosmithkline Biologicals Sa Vacunas de combinación con menores dosis de antígeno y/o adyuvante

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