JP2015527361A5 - - Google Patents
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- Publication number
- JP2015527361A5 JP2015527361A5 JP2015528549A JP2015528549A JP2015527361A5 JP 2015527361 A5 JP2015527361 A5 JP 2015527361A5 JP 2015528549 A JP2015528549 A JP 2015528549A JP 2015528549 A JP2015528549 A JP 2015528549A JP 2015527361 A5 JP2015527361 A5 JP 2015527361A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- liquid extract
- extraction solvent
- formulation
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 23
- 210000001519 tissue Anatomy 0.000 claims 18
- 239000007788 liquid Substances 0.000 claims 10
- 238000000605 extraction Methods 0.000 claims 6
- 239000002904 solvent Substances 0.000 claims 6
- 235000003373 curcuma longa Nutrition 0.000 claims 5
- 238000009472 formulation Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims 4
- 206010061218 Inflammation Diseases 0.000 claims 3
- 239000001215 curcuma longa l. root Substances 0.000 claims 3
- 239000002552 dosage form Substances 0.000 claims 3
- 230000004054 inflammatory process Effects 0.000 claims 3
- 210000004400 mucous membrane Anatomy 0.000 claims 3
- 235000003392 Curcuma domestica Nutrition 0.000 claims 2
- 244000008991 Curcuma longa Species 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 235000012754 curcumin Nutrition 0.000 claims 2
- 229940109262 curcumin Drugs 0.000 claims 2
- 239000004148 curcumin Substances 0.000 claims 2
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 claims 2
- 230000001804 emulsifying effect Effects 0.000 claims 2
- 239000000839 emulsion Substances 0.000 claims 2
- 230000002496 gastric effect Effects 0.000 claims 2
- 239000003921 oil Substances 0.000 claims 2
- 235000019198 oils Nutrition 0.000 claims 2
- 238000002791 soaking Methods 0.000 claims 2
- 235000013976 turmeric Nutrition 0.000 claims 2
- UEPVWRDHSPMIAZ-IZTHOABVSA-N (1e,4z,6e)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)hepta-1,4,6-trien-3-one Chemical compound C1=C(O)C(OC)=CC(\C=C\C(\O)=C\C(=O)\C=C\C=2C=CC(O)=CC=2)=C1 UEPVWRDHSPMIAZ-IZTHOABVSA-N 0.000 claims 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims 1
- HJTVQHVGMGKONQ-LUZURFALSA-N Curcumin II Natural products C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=CC(O)=CC=2)=C1 HJTVQHVGMGKONQ-LUZURFALSA-N 0.000 claims 1
- 206010058667 Oral toxicity Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 231100000460 acute oral toxicity Toxicity 0.000 claims 1
- JYTVKRNTTALBBZ-UHFFFAOYSA-N bis demethoxycurcumin Natural products C1=CC(O)=CC=C1C=CC(=O)CC(=O)C=CC1=CC=CC(O)=C1 JYTVKRNTTALBBZ-UHFFFAOYSA-N 0.000 claims 1
- PREBVFJICNPEKM-YDWXAUTNSA-N bisdemethoxycurcumin Chemical compound C1=CC(O)=CC=C1\C=C\C(=O)CC(=O)\C=C\C1=CC=C(O)C=C1 PREBVFJICNPEKM-YDWXAUTNSA-N 0.000 claims 1
- 235000012343 cottonseed oil Nutrition 0.000 claims 1
- 239000002385 cottonseed oil Substances 0.000 claims 1
- NMRUIRRIQNAQEB-UHFFFAOYSA-N demethoxycurcumin Natural products OC(=CC(C=CC1=CC(=C(C=C1)O)OC)=O)C=CC1=CC=C(C=C1)O NMRUIRRIQNAQEB-UHFFFAOYSA-N 0.000 claims 1
- YXAKCQIIROBKOP-UHFFFAOYSA-N di-p-hydroxycinnamoylmethane Natural products C=1C=C(O)C=CC=1C=CC(=O)C=C(O)C=CC1=CC=C(O)C=C1 YXAKCQIIROBKOP-UHFFFAOYSA-N 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 231100000053 low toxicity Toxicity 0.000 claims 1
- 231100000252 nontoxic Toxicity 0.000 claims 1
- 230000003000 nontoxic effect Effects 0.000 claims 1
- 231100000418 oral toxicity Toxicity 0.000 claims 1
- UEPVWRDHSPMIAZ-UHFFFAOYSA-N p-hydroxycinnamoyl feruloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(O)=CC(=O)C=CC=2C=CC(O)=CC=2)=C1 UEPVWRDHSPMIAZ-UHFFFAOYSA-N 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/590,188 US20140056828A1 (en) | 2012-08-21 | 2012-08-21 | Novel formulations and uses for curcuma extracts |
| US13/590,188 | 2012-08-21 | ||
| PCT/US2013/055499 WO2014031504A1 (en) | 2012-08-21 | 2013-08-19 | Novel formulations and uses for curcuma extracts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015527361A JP2015527361A (ja) | 2015-09-17 |
| JP2015527361A5 true JP2015527361A5 (enExample) | 2016-10-06 |
Family
ID=50148166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015528549A Pending JP2015527361A (ja) | 2012-08-21 | 2013-08-19 | ウコン属抽出物のための新規の処方物および使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (6) | US20140056828A1 (enExample) |
| EP (4) | EP3636273B1 (enExample) |
| JP (1) | JP2015527361A (enExample) |
| CN (1) | CN104717969A (enExample) |
| AU (1) | AU2013306104B2 (enExample) |
| HK (1) | HK1211834A1 (enExample) |
| WO (1) | WO2014031504A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140056828A1 (en) | 2012-08-21 | 2014-02-27 | Indiran Pather | Novel formulations and uses for curcuma extracts |
| EP3129003A1 (en) * | 2014-04-08 | 2017-02-15 | University of Massachusetts | Food matrices and methods of making and using |
| WO2016061284A1 (en) * | 2014-10-14 | 2016-04-21 | Biocogent, Llc | Compositions and methods comprising extracts of zingiberaceae |
| US11576853B2 (en) * | 2015-04-29 | 2023-02-14 | CSI: Create.Solve. Innovate. LLC | Antioxidant compositions and methods of protecting skin, hair and nails against high energy blue-violet light |
| KR101858095B1 (ko) | 2015-11-26 | 2018-05-15 | 우수정 | 커큐민을 포함하는 강황 추출물을 유효 성분으로 포함하는 피부 미백, 주름 형성 억제, 및 소양증 완화용 화장품 조성물 |
| JP6805514B2 (ja) * | 2016-03-18 | 2020-12-23 | 日油株式会社 | 脱脂米ぬか抽出物を含有する組成物 |
| KR20180033747A (ko) * | 2016-09-26 | 2018-04-04 | 계명대학교 산학협력단 | 유화제 및 초음파를 이용한 강황으로부터 고함량의 커큐민 추출방법 |
| IL248148B (en) * | 2016-09-29 | 2021-09-30 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | A method for extracting a compound from plant origin |
| IL248150B (en) | 2016-09-29 | 2018-05-31 | Garti Nissim | Method for selective extraction of cannabinoids from a plant source |
| IL248149B (en) | 2016-09-29 | 2020-03-31 | Garti Nissim | Formulations of dilutable cannabinoids and processes for their preparation |
| KR101855989B1 (ko) * | 2016-12-23 | 2018-05-09 | 강원대학교산학협력단 | 가용화제를 첨가한 물을 추출용매로 이용한 유용성분이 증가된 메밀 종자 추출물의 제조 방법 및 그에 따른 메밀 종자 추출물 |
| US10422033B2 (en) * | 2017-02-22 | 2019-09-24 | King Saud University | Green method for coating a substrate with silver nanoparticles |
| CN107456397B (zh) * | 2017-06-07 | 2021-06-15 | 青蛙王子（福建）婴童护理用品有限公司 | 儿童用姜黄素bb霜及其制备方法 |
| CN109315447A (zh) * | 2017-07-31 | 2019-02-12 | 安树义 | 一种果蔬霜霉病杀菌水剂及其生产工艺 |
| WO2019047002A1 (zh) * | 2017-09-05 | 2019-03-14 | 拉芳家化股份有限公司 | 一种含有抗氧化剂的化妆品组合物 |
| WO2019104050A1 (en) * | 2017-11-27 | 2019-05-31 | Lodaat Pharmaceuticals | Methods for preparing curcuminoid compositions |
| CN108743496B (zh) * | 2018-05-17 | 2021-06-11 | 珀莱雅化妆品股份有限公司 | 一种防晒增效微囊粉及其制备方法 |
| KR102298839B1 (ko) * | 2019-01-04 | 2021-09-07 | 주식회사 디네이쳐 | 천연물질의 선택적 추출 방법 |
| WO2020206040A1 (en) * | 2019-04-01 | 2020-10-08 | Aveta Biomics, Inc. | Methods and compositions for treating dysbiosis of oral microbiome |
| WO2020214600A1 (en) * | 2019-04-14 | 2020-10-22 | The Regents Of The University Of California | A sensitive lc-ms assay to measure curcuminoids in complex biological samples |
| SG10201906913YA (en) * | 2019-07-26 | 2021-02-25 | Aastar Pte Ltd | Pharmaceutical preparation with curcuminoids nanoparticles and a method for producing the same |
| IT202000026236A1 (it) * | 2020-11-04 | 2022-05-04 | Iromed Group S R L | Composizione oftalmica |
| US11298321B1 (en) | 2021-07-12 | 2022-04-12 | King Abdulaziz University | Methods for treating metabolic disorder |
| US11253481B1 (en) | 2021-07-12 | 2022-02-22 | King Abdulaziz University | Self-nanoemulsifying 3D-printed tablet composition and method of use thereof |
| WO2023004522A1 (es) * | 2021-07-28 | 2023-02-02 | Universidad San Sebastián | Nanoemulsión para el cuidado de la piel con bioactivos a base de curcumina y micosporina |
| JP7321229B2 (ja) * | 2021-10-20 | 2023-08-04 | 義美食品股▲ふん▼有限公司 | ウコン根茎からクルクミノイドを分離する方法 |
| CN116210730B (zh) * | 2021-12-02 | 2024-04-02 | 四川省新兰月生物科技有限公司 | 柑橘防日灼的农药组合物 |
| CN114191526A (zh) * | 2021-12-10 | 2022-03-18 | 佛山市连艺生物科技有限公司 | 红火炬郁金精油在制备抗紫外光老化药物中的应用 |
| CN114209798A (zh) * | 2021-12-10 | 2022-03-22 | 佛山市连艺生物科技有限公司 | 红火炬郁金醇提取物在制备抗紫外光老化药物中的应用 |
| CN114306191B (zh) * | 2022-01-28 | 2024-01-09 | 海南医学院 | 一种天然植物防晒霜及其制备方法 |
| CN115501182A (zh) * | 2022-09-22 | 2022-12-23 | 武汉市农业科学院 | 一种牛蒡苷元液体纳米制剂及其制备方法 |
| US11805995B1 (en) * | 2022-11-22 | 2023-11-07 | King Faisal University | Saliva collection kit |
| JP2025007699A (ja) * | 2023-07-03 | 2025-01-17 | 国立大学法人神戸大学 | ヒストン脱アセチル化酵素４異常に伴う皮膚障害の予防及び／又は治療剤 |
| IT202300020355A1 (it) * | 2023-10-03 | 2025-04-03 | Erbagil S R L | Sistema estrattivo multifasico (s.e.m.) a tecniche combinate di estrazione di composti bioattivi da matrici vegetali e veicoli contenenti gli stessi |
| WO2025078841A2 (en) | 2023-10-11 | 2025-04-17 | Antikor Biopharma Limited | Antibodies, conjugates, and uses thereof |
| WO2025137752A1 (pt) * | 2023-12-29 | 2025-07-03 | Maciel Iara Mendes | PROCESSO DE OBTENÇÃO DE NANOESTRUTURAS COMPREENDENDO Curcuma longa; NANOESTRUTURAS DE C. longa; COMPOSIÇÕES COMPREENDENDO AS NANOESTRUTURAS DE C. longa |
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|---|---|---|---|---|
| GB8925473D0 (en) * | 1989-11-10 | 1989-12-28 | Unilever Plc | Sunscreen compositions |
| US5861415A (en) * | 1996-07-12 | 1999-01-19 | Sami Chemicals & Extracts, Ltd. | Bioprotectant composition, method of use and extraction process of curcuminoids |
| US7858331B2 (en) * | 2000-11-03 | 2010-12-28 | Dana Farber Cancer Institute, Inc. | Compositions and methods for the treatment of cancer |
| JP2003137799A (ja) | 2001-03-28 | 2003-05-14 | Kiyotoshi Oshiro | ウコン含有ジアシルグリセロール溶液とその製造方法。 |
| US8206753B2 (en) * | 2001-06-20 | 2012-06-26 | Metaproteomics, Llc | Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes |
| US20040121031A1 (en) * | 2002-12-09 | 2004-06-24 | Muhammed Majeed | Novel topical skin care and nutraceutical applications of Glabridin or extracts containing a defined amount (4-90%) of Glabridin |
| US7968115B2 (en) | 2004-03-05 | 2011-06-28 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of cancer |
| CN1274300C (zh) | 2003-12-11 | 2006-09-13 | 中国科学院生物物理研究所 | 用于改善姜黄素溶出度和生物利用度的药物组合物及其制备方法 |
| JP2005194246A (ja) | 2004-01-09 | 2005-07-21 | Ichimaru Pharcos Co Ltd | ＮＦ−κＢ活性化抑制剤 |
| JPWO2005097152A1 (ja) | 2004-03-31 | 2008-02-28 | 株式会社カネカ | 粘結性が改善されたウコン抽出物含有組成物 |
| US20060045928A1 (en) * | 2004-08-31 | 2006-03-02 | Seiri Oshiro | Composition containing herbal medicine component for promoting absorption and production method thereof |
| PL1890546T3 (pl) | 2005-05-30 | 2019-04-30 | Benny Antony | Sposób poprawiania biodostępności kurkuminy |
| US7763289B2 (en) | 2005-09-01 | 2010-07-27 | JoAl's Products, LLC | Topical turmeric skin care products |
| EP1933625B1 (en) * | 2005-10-13 | 2014-07-09 | Laila Nutraceuticals | Process for producing enriched fractions of tetrahydroxycurcumin and tetrahydrotetrahydroxy-curcumin from the extracts of curcuma longa |
| US20070196318A1 (en) | 2006-02-22 | 2007-08-23 | Marini Jan L | Cosmetic herbal compositions |
| KR20090007564A (ko) * | 2006-03-17 | 2009-01-19 | 허발사이언스 싱가포르 피티이 리미티드 | 쿠르쿠마 종을 포함한 추출물 및 이를 수득하는 방법 |
| JP2007320864A (ja) | 2006-05-30 | 2007-12-13 | Toshihiko Osawa | 非アルコール性脂肪肝炎予防・治療用組成物 |
| CA2701190C (en) * | 2007-10-03 | 2017-12-05 | Sabell Corporation | Herbal compositions and methods for treating hepatic disorders |
| TW201019949A (en) | 2008-10-16 | 2010-06-01 | Herbalscience Group Llc | Extracts of curcuma and methods of use thereof |
| US20100105644A1 (en) | 2008-10-27 | 2010-04-29 | The Regents Of The University Of Michigan | Botanical composition for enhanced skin repair and uses thereof |
| AU2009329035A1 (en) * | 2008-12-01 | 2011-06-23 | Laila Pharmaceuticals Pvt. Ltd. | Topical formulation(s) for the treatment of inflammation, skin and mucosal disorders and other diseases thereof |
| IL210587A0 (en) * | 2011-01-12 | 2011-03-31 | Adel Jamil Hidmi | Natural preparation for treatment of skin sores and lesions |
| US20140056828A1 (en) | 2012-08-21 | 2014-02-27 | Indiran Pather | Novel formulations and uses for curcuma extracts |
-
2012
- 2012-08-21 US US13/590,188 patent/US20140056828A1/en not_active Abandoned
- 2012-12-17 US US13/717,677 patent/US10231940B2/en active Active
- 2012-12-17 US US13/717,670 patent/US8815220B2/en active Active
-
2013
- 2013-08-19 EP EP19214450.9A patent/EP3636273B1/en active Active
- 2013-08-19 EP EP22205174.0A patent/EP4147707A1/en active Pending
- 2013-08-19 WO PCT/US2013/055499 patent/WO2014031504A1/en not_active Ceased
- 2013-08-19 EP EP13830806.9A patent/EP2887950A4/en not_active Withdrawn
- 2013-08-19 HK HK15112645.7A patent/HK1211834A1/xx unknown
- 2013-08-19 AU AU2013306104A patent/AU2013306104B2/en active Active
- 2013-08-19 EP EP21205715.2A patent/EP3981418B1/en active Active
- 2013-08-19 JP JP2015528549A patent/JP2015527361A/ja active Pending
- 2013-08-19 CN CN201380052627.5A patent/CN104717969A/zh active Pending
-
2019
- 2019-01-31 US US16/264,301 patent/US10973778B2/en active Active
-
2021
- 2021-03-10 US US17/198,102 patent/US12053439B2/en active Active
-
2024
- 2024-06-24 US US18/752,500 patent/US20240342112A1/en active Pending
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