JP2015527361A5 - - Google Patents
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- Publication number
- JP2015527361A5 JP2015527361A5 JP2015528549A JP2015528549A JP2015527361A5 JP 2015527361 A5 JP2015527361 A5 JP 2015527361A5 JP 2015528549 A JP2015528549 A JP 2015528549A JP 2015528549 A JP2015528549 A JP 2015528549A JP 2015527361 A5 JP2015527361 A5 JP 2015527361A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- liquid extract
- extraction solvent
- formulation
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 23
- 210000001519 tissue Anatomy 0.000 claims 18
- 239000007788 liquid Substances 0.000 claims 10
- 238000000605 extraction Methods 0.000 claims 6
- 239000002904 solvent Substances 0.000 claims 6
- 235000003373 curcuma longa Nutrition 0.000 claims 5
- 238000009472 formulation Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims 4
- 206010061218 Inflammation Diseases 0.000 claims 3
- 239000001215 curcuma longa l. root Substances 0.000 claims 3
- 239000002552 dosage form Substances 0.000 claims 3
- 230000004054 inflammatory process Effects 0.000 claims 3
- 210000004400 mucous membrane Anatomy 0.000 claims 3
- 235000003392 Curcuma domestica Nutrition 0.000 claims 2
- 244000008991 Curcuma longa Species 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 235000012754 curcumin Nutrition 0.000 claims 2
- 229940109262 curcumin Drugs 0.000 claims 2
- 239000004148 curcumin Substances 0.000 claims 2
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 claims 2
- 230000001804 emulsifying effect Effects 0.000 claims 2
- 239000000839 emulsion Substances 0.000 claims 2
- 230000002496 gastric effect Effects 0.000 claims 2
- 239000003921 oil Substances 0.000 claims 2
- 235000019198 oils Nutrition 0.000 claims 2
- 238000002791 soaking Methods 0.000 claims 2
- 235000013976 turmeric Nutrition 0.000 claims 2
- UEPVWRDHSPMIAZ-IZTHOABVSA-N (1e,4z,6e)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)hepta-1,4,6-trien-3-one Chemical compound C1=C(O)C(OC)=CC(\C=C\C(\O)=C\C(=O)\C=C\C=2C=CC(O)=CC=2)=C1 UEPVWRDHSPMIAZ-IZTHOABVSA-N 0.000 claims 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims 1
- HJTVQHVGMGKONQ-LUZURFALSA-N Curcumin II Natural products C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=CC(O)=CC=2)=C1 HJTVQHVGMGKONQ-LUZURFALSA-N 0.000 claims 1
- 206010058667 Oral toxicity Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 231100000460 acute oral toxicity Toxicity 0.000 claims 1
- JYTVKRNTTALBBZ-UHFFFAOYSA-N bis demethoxycurcumin Natural products C1=CC(O)=CC=C1C=CC(=O)CC(=O)C=CC1=CC=CC(O)=C1 JYTVKRNTTALBBZ-UHFFFAOYSA-N 0.000 claims 1
- PREBVFJICNPEKM-YDWXAUTNSA-N bisdemethoxycurcumin Chemical compound C1=CC(O)=CC=C1\C=C\C(=O)CC(=O)\C=C\C1=CC=C(O)C=C1 PREBVFJICNPEKM-YDWXAUTNSA-N 0.000 claims 1
- 235000012343 cottonseed oil Nutrition 0.000 claims 1
- 239000002385 cottonseed oil Substances 0.000 claims 1
- NMRUIRRIQNAQEB-UHFFFAOYSA-N demethoxycurcumin Natural products OC(=CC(C=CC1=CC(=C(C=C1)O)OC)=O)C=CC1=CC=C(C=C1)O NMRUIRRIQNAQEB-UHFFFAOYSA-N 0.000 claims 1
- YXAKCQIIROBKOP-UHFFFAOYSA-N di-p-hydroxycinnamoylmethane Natural products C=1C=C(O)C=CC=1C=CC(=O)C=C(O)C=CC1=CC=C(O)C=C1 YXAKCQIIROBKOP-UHFFFAOYSA-N 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 231100000053 low toxicity Toxicity 0.000 claims 1
- 231100000252 nontoxic Toxicity 0.000 claims 1
- 230000003000 nontoxic effect Effects 0.000 claims 1
- 231100000418 oral toxicity Toxicity 0.000 claims 1
- UEPVWRDHSPMIAZ-UHFFFAOYSA-N p-hydroxycinnamoyl feruloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(O)=CC(=O)C=CC=2C=CC(O)=CC=2)=C1 UEPVWRDHSPMIAZ-UHFFFAOYSA-N 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/590,188 | 2012-08-21 | ||
| US13/590,188 US20140056828A1 (en) | 2012-08-21 | 2012-08-21 | Novel formulations and uses for curcuma extracts |
| PCT/US2013/055499 WO2014031504A1 (en) | 2012-08-21 | 2013-08-19 | Novel formulations and uses for curcuma extracts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015527361A JP2015527361A (ja) | 2015-09-17 |
| JP2015527361A5 true JP2015527361A5 (enExample) | 2016-10-06 |
Family
ID=50148166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015528549A Pending JP2015527361A (ja) | 2012-08-21 | 2013-08-19 | ウコン属抽出物のための新規の処方物および使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (6) | US20140056828A1 (enExample) |
| EP (4) | EP3981418B1 (enExample) |
| JP (1) | JP2015527361A (enExample) |
| CN (1) | CN104717969A (enExample) |
| AU (1) | AU2013306104B2 (enExample) |
| HK (1) | HK1211834A1 (enExample) |
| WO (1) | WO2014031504A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140056828A1 (en) | 2012-08-21 | 2014-02-27 | Indiran Pather | Novel formulations and uses for curcuma extracts |
| EP3129003A1 (en) * | 2014-04-08 | 2017-02-15 | University of Massachusetts | Food matrices and methods of making and using |
| CN107405374A (zh) * | 2014-10-14 | 2017-11-28 | 比奥考金特有限责任公司 | 包含姜科提取物的组合物和方法 |
| US11576853B2 (en) * | 2015-04-29 | 2023-02-14 | CSI: Create.Solve. Innovate. LLC | Antioxidant compositions and methods of protecting skin, hair and nails against high energy blue-violet light |
| KR101858095B1 (ko) | 2015-11-26 | 2018-05-15 | 우수정 | 커큐민을 포함하는 강황 추출물을 유효 성분으로 포함하는 피부 미백, 주름 형성 억제, 및 소양증 완화용 화장품 조성물 |
| JP6805514B2 (ja) * | 2016-03-18 | 2020-12-23 | 日油株式会社 | 脱脂米ぬか抽出物を含有する組成物 |
| KR20180033747A (ko) * | 2016-09-26 | 2018-04-04 | 계명대학교 산학협력단 | 유화제 및 초음파를 이용한 강황으로부터 고함량의 커큐민 추출방법 |
| IL248150B (en) | 2016-09-29 | 2018-05-31 | Garti Nissim | Method for selective extraction of cannabinoids from a plant source |
| IL248148B (en) | 2016-09-29 | 2021-09-30 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | A method for extracting a compound from plant origin |
| IL248149B (en) | 2016-09-29 | 2020-03-31 | Garti Nissim | Formulations of dilutable cannabinoids and processes for their preparation |
| KR101855989B1 (ko) * | 2016-12-23 | 2018-05-09 | 강원대학교산학협력단 | 가용화제를 첨가한 물을 추출용매로 이용한 유용성분이 증가된 메밀 종자 추출물의 제조 방법 및 그에 따른 메밀 종자 추출물 |
| US10422033B2 (en) * | 2017-02-22 | 2019-09-24 | King Saud University | Green method for coating a substrate with silver nanoparticles |
| CN107456397B (zh) * | 2017-06-07 | 2021-06-15 | 青蛙王子（福建）婴童护理用品有限公司 | 儿童用姜黄素bb霜及其制备方法 |
| CN109315447A (zh) * | 2017-07-31 | 2019-02-12 | 安树义 | 一种果蔬霜霉病杀菌水剂及其生产工艺 |
| CN108697601A (zh) * | 2017-09-05 | 2018-10-23 | 拉芳家化股份有限公司 | 一种含有抗氧化剂的化妆品组合物 |
| US11413257B2 (en) | 2017-11-27 | 2022-08-16 | Lodaat Pharmaceuticals | Methods for preparing curcuminoid compositions |
| CN108743496B (zh) * | 2018-05-17 | 2021-06-11 | 珀莱雅化妆品股份有限公司 | 一种防晒增效微囊粉及其制备方法 |
| KR102298839B1 (ko) * | 2019-01-04 | 2021-09-07 | 주식회사 디네이쳐 | 천연물질의 선택적 추출 방법 |
| EP3946393A4 (en) * | 2019-04-01 | 2023-01-11 | Aveta Biomics, Inc. | METHODS AND COMPOSITIONS FOR THE TREATMENT OF DYSBIosis OF ORAL MICROBIOMA |
| US20220178936A1 (en) * | 2019-04-14 | 2022-06-09 | The Regents Of The University Of California | A sensitive lc-ms assay to measure curcuminoids in complex biological samples |
| SG10201906913YA (en) | 2019-07-26 | 2021-02-25 | Aastar Pte Ltd | Pharmaceutical preparation with curcuminoids nanoparticles and a method for producing the same |
| IT202000026236A1 (it) * | 2020-11-04 | 2022-05-04 | Iromed Group S R L | Composizione oftalmica |
| MX2023012562A (es) * | 2021-04-30 | 2023-10-30 | Sami Sabinsa Group Ltd | Composiciones para el tratamiento del sindrome de ovario poliquistico. |
| US11253481B1 (en) | 2021-07-12 | 2022-02-22 | King Abdulaziz University | Self-nanoemulsifying 3D-printed tablet composition and method of use thereof |
| US11298321B1 (en) | 2021-07-12 | 2022-04-12 | King Abdulaziz University | Methods for treating metabolic disorder |
| WO2023004522A1 (es) * | 2021-07-28 | 2023-02-02 | Universidad San Sebastián | Nanoemulsión para el cuidado de la piel con bioactivos a base de curcumina y micosporina |
| JP7321229B2 (ja) * | 2021-10-20 | 2023-08-04 | 義美食品股▲ふん▼有限公司 | ウコン根茎からクルクミノイドを分離する方法 |
| CN116210730B (zh) * | 2021-12-02 | 2024-04-02 | 四川省新兰月生物科技有限公司 | 柑橘防日灼的农药组合物 |
| CN114209798A (zh) * | 2021-12-10 | 2022-03-22 | 佛山市连艺生物科技有限公司 | 红火炬郁金醇提取物在制备抗紫外光老化药物中的应用 |
| CN114191526A (zh) * | 2021-12-10 | 2022-03-18 | 佛山市连艺生物科技有限公司 | 红火炬郁金精油在制备抗紫外光老化药物中的应用 |
| CN114306191B (zh) * | 2022-01-28 | 2024-01-09 | 海南医学院 | 一种天然植物防晒霜及其制备方法 |
| CN115501182A (zh) * | 2022-09-22 | 2022-12-23 | 武汉市农业科学院 | 一种牛蒡苷元液体纳米制剂及其制备方法 |
| US11805995B1 (en) * | 2022-11-22 | 2023-11-07 | King Faisal University | Saliva collection kit |
| JP2025007699A (ja) * | 2023-07-03 | 2025-01-17 | 国立大学法人神戸大学 | ヒストン脱アセチル化酵素４異常に伴う皮膚障害の予防及び／又は治療剤 |
| IT202300020355A1 (it) * | 2023-10-03 | 2025-04-03 | Erbagil S R L | Sistema estrattivo multifasico (s.e.m.) a tecniche combinate di estrazione di composti bioattivi da matrici vegetali e veicoli contenenti gli stessi |
| WO2025078841A2 (en) | 2023-10-11 | 2025-04-17 | Antikor Biopharma Limited | Antibodies, conjugates, and uses thereof |
| WO2025137752A1 (pt) * | 2023-12-29 | 2025-07-03 | Maciel Iara Mendes | PROCESSO DE OBTENÇÃO DE NANOESTRUTURAS COMPREENDENDO Curcuma longa; NANOESTRUTURAS DE C. longa; COMPOSIÇÕES COMPREENDENDO AS NANOESTRUTURAS DE C. longa |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8925473D0 (en) * | 1989-11-10 | 1989-12-28 | Unilever Plc | Sunscreen compositions |
| US5861415A (en) * | 1996-07-12 | 1999-01-19 | Sami Chemicals & Extracts, Ltd. | Bioprotectant composition, method of use and extraction process of curcuminoids |
| US7858331B2 (en) * | 2000-11-03 | 2010-12-28 | Dana Farber Cancer Institute, Inc. | Compositions and methods for the treatment of cancer |
| JP2003137799A (ja) | 2001-03-28 | 2003-05-14 | Kiyotoshi Oshiro | ウコン含有ジアシルグリセロール溶液とその製造方法。 |
| US8206753B2 (en) * | 2001-06-20 | 2012-06-26 | Metaproteomics, Llc | Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes |
| US20040121031A1 (en) * | 2002-12-09 | 2004-06-24 | Muhammed Majeed | Novel topical skin care and nutraceutical applications of Glabridin or extracts containing a defined amount (4-90%) of Glabridin |
| US7968115B2 (en) | 2004-03-05 | 2011-06-28 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of cancer |
| CN1274300C (zh) | 2003-12-11 | 2006-09-13 | 中国科学院生物物理研究所 | 用于改善姜黄素溶出度和生物利用度的药物组合物及其制备方法 |
| JP2005194246A (ja) | 2004-01-09 | 2005-07-21 | Ichimaru Pharcos Co Ltd | ＮＦ−κＢ活性化抑制剤 |
| JPWO2005097152A1 (ja) | 2004-03-31 | 2008-02-28 | 株式会社カネカ | 粘結性が改善されたウコン抽出物含有組成物 |
| US20060045928A1 (en) * | 2004-08-31 | 2006-03-02 | Seiri Oshiro | Composition containing herbal medicine component for promoting absorption and production method thereof |
| PL1890546T3 (pl) | 2005-05-30 | 2019-04-30 | Benny Antony | Sposób poprawiania biodostępności kurkuminy |
| US7763289B2 (en) | 2005-09-01 | 2010-07-27 | JoAl's Products, LLC | Topical turmeric skin care products |
| CN101227823B (zh) * | 2005-10-13 | 2012-05-23 | 莱拉营养食品有限公司 | 从姜黄提取物中制取四羟基姜黄色素和四氢四羟基姜黄色素浓缩成分的方法 |
| US20070196318A1 (en) | 2006-02-22 | 2007-08-23 | Marini Jan L | Cosmetic herbal compositions |
| MX2008011754A (es) * | 2006-03-17 | 2008-09-30 | Herbalscience Singapore Pte Ltd | Extractos y metodos que comprenden especies de curcuma. |
| JP2007320864A (ja) | 2006-05-30 | 2007-12-13 | Toshihiko Osawa | 非アルコール性脂肪肝炎予防・治療用組成物 |
| MX2010003726A (es) * | 2007-10-03 | 2010-09-14 | Sabell Corp | Composiciones herbarias y metodos de tratamiento de trastornos hepaticos. |
| TW201019949A (en) | 2008-10-16 | 2010-06-01 | Herbalscience Group Llc | Extracts of curcuma and methods of use thereof |
| US20100105644A1 (en) | 2008-10-27 | 2010-04-29 | The Regents Of The University Of Michigan | Botanical composition for enhanced skin repair and uses thereof |
| AU2009329035A1 (en) | 2008-12-01 | 2011-06-23 | Laila Pharmaceuticals Pvt. Ltd. | Topical formulation(s) for the treatment of inflammation, skin and mucosal disorders and other diseases thereof |
| IL210587A0 (en) | 2011-01-12 | 2011-03-31 | Adel Jamil Hidmi | Natural preparation for treatment of skin sores and lesions |
| US20140056828A1 (en) | 2012-08-21 | 2014-02-27 | Indiran Pather | Novel formulations and uses for curcuma extracts |
-
2012
- 2012-08-21 US US13/590,188 patent/US20140056828A1/en not_active Abandoned
- 2012-12-17 US US13/717,677 patent/US10231940B2/en active Active
- 2012-12-17 US US13/717,670 patent/US8815220B2/en active Active
-
2013
- 2013-08-19 HK HK15112645.7A patent/HK1211834A1/xx unknown
- 2013-08-19 JP JP2015528549A patent/JP2015527361A/ja active Pending
- 2013-08-19 EP EP21205715.2A patent/EP3981418B1/en active Active
- 2013-08-19 EP EP19214450.9A patent/EP3636273B1/en active Active
- 2013-08-19 WO PCT/US2013/055499 patent/WO2014031504A1/en not_active Ceased
- 2013-08-19 AU AU2013306104A patent/AU2013306104B2/en active Active
- 2013-08-19 EP EP13830806.9A patent/EP2887950A4/en not_active Withdrawn
- 2013-08-19 CN CN201380052627.5A patent/CN104717969A/zh active Pending
- 2013-08-19 EP EP22205174.0A patent/EP4147707A1/en active Pending
-
2019
- 2019-01-31 US US16/264,301 patent/US10973778B2/en active Active
-
2021
- 2021-03-10 US US17/198,102 patent/US12053439B2/en active Active
-
2024
- 2024-06-24 US US18/752,500 patent/US20240342112A1/en active Pending
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