JP2015523986A - ラキニモドを使用する眼炎症性疾患の治療 - Google Patents

ラキニモドを使用する眼炎症性疾患の治療 Download PDF

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Publication number
JP2015523986A
JP2015523986A JP2015516113A JP2015516113A JP2015523986A JP 2015523986 A JP2015523986 A JP 2015523986A JP 2015516113 A JP2015516113 A JP 2015516113A JP 2015516113 A JP2015516113 A JP 2015516113A JP 2015523986 A JP2015523986 A JP 2015523986A
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Prior art keywords
laquinimod
pharmaceutically acceptable
acceptable salt
subject
effective amount
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Pending
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JP2015516113A
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English (en)
Japanese (ja)
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JP2015523986A5 (enExample
Inventor
カイェ、ジョエル
ハラーク、フセイン
タルシック、ノラ
Original Assignee
テバ ファーマシューティカル インダストリーズ リミティド
テバ ファーマシューティカル インダストリーズ リミティド
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Publication of JP2015523986A publication Critical patent/JP2015523986A/ja
Publication of JP2015523986A5 publication Critical patent/JP2015523986A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015516113A 2012-06-05 2013-06-04 ラキニモドを使用する眼炎症性疾患の治療 Pending JP2015523986A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261655526P 2012-06-05 2012-06-05
US61/655,526 2012-06-05
PCT/US2013/044058 WO2013184650A2 (en) 2012-06-05 2013-06-04 Treatment of ocular inflammatory diseases using laquinimod

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017158674A Division JP2018024677A (ja) 2012-06-05 2017-08-21 ラキニモドを使用する眼炎症性疾患の治療

Publications (2)

Publication Number Publication Date
JP2015523986A true JP2015523986A (ja) 2015-08-20
JP2015523986A5 JP2015523986A5 (enExample) 2016-07-21

Family

ID=49671002

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015516113A Pending JP2015523986A (ja) 2012-06-05 2013-06-04 ラキニモドを使用する眼炎症性疾患の治療
JP2017158674A Withdrawn JP2018024677A (ja) 2012-06-05 2017-08-21 ラキニモドを使用する眼炎症性疾患の治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017158674A Withdrawn JP2018024677A (ja) 2012-06-05 2017-08-21 ラキニモドを使用する眼炎症性疾患の治療

Country Status (10)

Country Link
US (6) US20130324574A1 (enExample)
EP (1) EP2854767A4 (enExample)
JP (2) JP2015523986A (enExample)
AR (1) AR092842A1 (enExample)
CA (1) CA2874767A1 (enExample)
IL (1) IL235874A0 (enExample)
RU (1) RU2014151992A (enExample)
TW (1) TW201400117A (enExample)
UY (1) UY34843A (enExample)
WO (1) WO2013184650A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023509336A (ja) * 2019-12-19 2023-03-08 アクティブ バイオテック エービー 過剰血管新生に関連する眼疾患を治療する化合物

Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
WO2013116657A1 (en) 2012-02-03 2013-08-08 Teva Pharmaceutical Industries Ltd. USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNFα THERAPY
TW201400117A (zh) * 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
TW201410244A (zh) 2012-08-13 2014-03-16 Teva Pharma 用於治療ｇａｂａ媒介之疾病之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ）
WO2015073697A1 (en) * 2013-11-15 2015-05-21 Teva Pharmaceutical Industries Ltd. Treatment of glaucoma using laquinimod
HK1231413A1 (zh) 2014-04-29 2017-12-22 Teva Pharmaceutical Industries Ltd. 用於治疗具有高残疾状况的复发-缓解型多发性硬化症(rrms)的患者的拉喹莫德
AU2022248724A1 (en) * 2021-04-01 2023-11-02 Active Biotech Ab Laquinimod formulation for ocular use

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Cited By (2)

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JP2023509336A (ja) * 2019-12-19 2023-03-08 アクティブ バイオテック エービー 過剰血管新生に関連する眼疾患を治療する化合物
JP7730816B2 (ja) 2019-12-19 2025-08-28 アクティブ バイオテック エービー 過剰血管新生に関連する眼疾患を治療する化合物

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US20130324574A1 (en) 2013-12-05
AR092842A1 (es) 2015-05-06
US20170231971A1 (en) 2017-08-17
UY34843A (es) 2013-12-31
US11654140B2 (en) 2023-05-23
WO2013184650A3 (en) 2015-07-02
WO2013184650A2 (en) 2013-12-12
IL235874A0 (en) 2015-01-29
US20180071275A1 (en) 2018-03-15
US20170333420A1 (en) 2017-11-23
TW201400117A (zh) 2014-01-01
US20250134881A1 (en) 2025-05-01
EP2854767A4 (en) 2016-04-27
RU2014151992A (ru) 2016-07-27
JP2018024677A (ja) 2018-02-15
US20210386731A1 (en) 2021-12-16
CA2874767A1 (en) 2013-12-12
EP2854767A2 (en) 2015-04-08

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