JP2015522083A5 - - Google Patents
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- Publication number
- JP2015522083A5 JP2015522083A5 JP2015521871A JP2015521871A JP2015522083A5 JP 2015522083 A5 JP2015522083 A5 JP 2015522083A5 JP 2015521871 A JP2015521871 A JP 2015521871A JP 2015521871 A JP2015521871 A JP 2015521871A JP 2015522083 A5 JP2015522083 A5 JP 2015522083A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- dihydromyricetin
- product
- composition
- cosmetic product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- KJXSIXMJHKAJOD-LSDHHAIUSA-N Ampelopsin Natural products C1([C@@H]2[C@H](C(C3=C(O)C=C(O)C=C3O2)=O)O)=CC(O)=C(O)C(O)=C1 KJXSIXMJHKAJOD-LSDHHAIUSA-N 0.000 claims description 180
- KQILIWXGGKGKNX-UHFFFAOYSA-N dihydromyricetin Natural products OC1C(=C(Oc2cc(O)cc(O)c12)c3cc(O)c(O)c(O)c3)O KQILIWXGGKGKNX-UHFFFAOYSA-N 0.000 claims description 155
- -1 dihydromyricetin compound Chemical class 0.000 claims description 139
- 238000000034 method Methods 0.000 claims description 82
- 239000002537 cosmetic Substances 0.000 claims description 80
- 125000000217 alkyl group Chemical group 0.000 claims description 53
- 125000004404 heteroalkyl group Chemical group 0.000 claims description 46
- 150000003839 salts Chemical class 0.000 claims description 46
- 241000196324 Embryophyta Species 0.000 claims description 41
- 239000000203 mixture Substances 0.000 claims description 41
- 150000001875 compounds Chemical class 0.000 claims description 40
- 229910052739 hydrogen Inorganic materials 0.000 claims description 38
- 239000001257 hydrogen Substances 0.000 claims description 38
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 38
- 125000004450 alkenylene group Chemical group 0.000 claims description 30
- 125000002947 alkylene group Chemical group 0.000 claims description 30
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
- 125000003342 alkenyl group Chemical group 0.000 claims description 23
- 125000003545 alkoxy group Chemical group 0.000 claims description 23
- 125000001475 halogen functional group Chemical group 0.000 claims description 23
- 125000005017 substituted alkenyl group Chemical group 0.000 claims description 23
- 125000000547 substituted alkyl group Chemical group 0.000 claims description 23
- 239000000463 material Substances 0.000 claims description 17
- 125000004398 2-methyl-2-butyl group Chemical group CC(C)(CC)* 0.000 claims description 15
- 125000006232 ethoxy propyl group Chemical group [H]C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 15
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 15
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 claims description 15
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 15
- 125000001973 tert-pentyl group Chemical group [H]C([H])([H])C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 15
- 230000001815 facial effect Effects 0.000 claims description 12
- 201000004384 Alopecia Diseases 0.000 claims description 10
- 241001092400 Leptarrhena pyrolifolia Species 0.000 claims description 10
- 244000248162 Xanthoceras sorbifolium Species 0.000 claims description 9
- 235000008375 Decussocarpus nagi Nutrition 0.000 claims description 8
- 244000132436 Myrica rubra Species 0.000 claims description 8
- 235000014631 Myrica rubra Nutrition 0.000 claims description 8
- 239000008266 hair spray Substances 0.000 claims description 8
- 239000002453 shampoo Substances 0.000 claims description 8
- 240000001829 Catharanthus roseus Species 0.000 claims description 7
- 241000404305 Erica arborea Species 0.000 claims description 7
- 241001432232 Glochidion sumatranum Species 0.000 claims description 7
- 240000001794 Manilkara zapota Species 0.000 claims description 7
- 235000011339 Manilkara zapota Nutrition 0.000 claims description 7
- 241000124033 Salix Species 0.000 claims description 7
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 claims description 7
- 235000008586 Hovenia Nutrition 0.000 claims description 6
- 241000405398 Hovenia Species 0.000 claims description 6
- 241001018563 Nekemias grossedentata Species 0.000 claims description 6
- 235000008593 Pinus contorta Nutrition 0.000 claims description 6
- 241000218606 Pinus contorta Species 0.000 claims description 6
- 241000245187 Rhododendron ferrugineum Species 0.000 claims description 6
- 230000037326 chronic stress Effects 0.000 claims description 6
- 239000007933 dermal patch Substances 0.000 claims description 6
- 230000003676 hair loss Effects 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 210000004761 scalp Anatomy 0.000 claims description 6
- 230000000475 sunscreen effect Effects 0.000 claims description 6
- 239000000516 sunscreening agent Substances 0.000 claims description 6
- 230000003779 hair growth Effects 0.000 claims description 5
- 241000563984 Ampelopsis Species 0.000 claims description 4
- 208000010201 Exanthema Diseases 0.000 claims description 4
- 244000010000 Hovenia dulcis Species 0.000 claims description 4
- 235000008584 Hovenia dulcis Nutrition 0.000 claims description 4
- 235000009388 Parthenocissus quinquefolia Nutrition 0.000 claims description 4
- 235000005205 Pinus Nutrition 0.000 claims description 4
- 241000218602 Pinus <genus> Species 0.000 claims description 4
- 231100000360 alopecia Toxicity 0.000 claims description 4
- 230000003796 beauty Effects 0.000 claims description 4
- 201000005884 exanthem Diseases 0.000 claims description 4
- 230000003020 moisturizing effect Effects 0.000 claims description 4
- 230000003658 preventing hair loss Effects 0.000 claims description 4
- 206010037844 rash Diseases 0.000 claims description 4
- 235000009240 Xanthoceras sorbifolium Nutrition 0.000 claims description 3
- 230000001939 inductive effect Effects 0.000 claims description 3
- 230000009759 skin aging Effects 0.000 claims description 3
- 241000421432 Glochidion Species 0.000 claims description 2
- 230000002996 emotional effect Effects 0.000 claims description 2
- 208000024963 hair loss Diseases 0.000 claims description 2
- 230000003340 mental effect Effects 0.000 claims description 2
- 229940116852 myricetin Drugs 0.000 claims description 2
- PCOBUQBNVYZTBU-UHFFFAOYSA-N myricetin Natural products OC1=C(O)C(O)=CC(C=2OC3=CC(O)=C(O)C(O)=C3C(=O)C=2)=C1 PCOBUQBNVYZTBU-UHFFFAOYSA-N 0.000 claims description 2
- 235000007743 myricetin Nutrition 0.000 claims description 2
- 230000036620 skin dryness Effects 0.000 claims description 2
- 231100000046 skin rash Toxicity 0.000 claims description 2
- 239000004909 Moisturizer Substances 0.000 claims 2
- 230000001333 moisturizer Effects 0.000 claims 2
- 0 *C(*Oc1c(C(C([C@@](c(cc2O*C(O*)=*)cc(O*C(O*)=O)c2O*C(O)=O)O2)O)=O)c2cc(O*C(O*)=O)c1)=O Chemical compound *C(*Oc1c(C(C([C@@](c(cc2O*C(O*)=*)cc(O*C(O*)=O)c2O*C(O)=O)O2)O)=O)c2cc(O*C(O*)=O)c1)=O 0.000 description 5
- 230000032683 aging Effects 0.000 description 2
- 230000003659 hair regrowth Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261671624P | 2012-07-13 | 2012-07-13 | |
| US61/671,624 | 2012-07-13 | ||
| PCT/US2013/050399 WO2014012075A2 (en) | 2012-07-13 | 2013-07-12 | Compositions and methods for treating hair loss and delaying aging of skin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015522083A JP2015522083A (ja) | 2015-08-03 |
| JP2015522083A5 true JP2015522083A5 (enExample) | 2016-09-01 |
Family
ID=49916708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015521871A Pending JP2015522083A (ja) | 2012-07-13 | 2013-07-12 | 脱毛の処置および皮膚の加齢の遅延 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US9789047B2 (enExample) |
| EP (1) | EP2872133B1 (enExample) |
| JP (1) | JP2015522083A (enExample) |
| CN (1) | CN104797250A (enExample) |
| AU (1) | AU2013289963B2 (enExample) |
| CA (1) | CA2878914A1 (enExample) |
| ES (1) | ES2733351T3 (enExample) |
| HU (1) | HUE044816T2 (enExample) |
| MX (1) | MX362488B (enExample) |
| TW (1) | TWI669116B (enExample) |
| WO (1) | WO2014012075A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9789047B2 (en) | 2012-07-13 | 2017-10-17 | Phyto Tech Corp. | Treating hair loss and delaying aging of skin |
| CN107427474A (zh) | 2015-04-13 | 2017-12-01 | 株式会社Lg生活健康 | 含有调节神经递质释放的成分的可溶性微针 |
| KR101803201B1 (ko) | 2015-07-30 | 2017-11-30 | 성균관대학교산학협력단 | 미리세틴 유도체를 함유하는 snare 복합체 형성 억제용 조성물 |
| WO2017018847A1 (ko) * | 2015-07-30 | 2017-02-02 | 성균관대학교 산학협력단 | 미리세틴 유도체를 함유하는 snare 복합체 형성 억제용 조성물 |
| CN105816507A (zh) * | 2016-04-20 | 2016-08-03 | 中国科学院武汉植物园 | 一种白芨愈伤护肤制剂及其制备方法 |
| CN107496241A (zh) * | 2017-09-07 | 2017-12-22 | 师海全 | 一种含有文冠果生物活性成分的面膜的制备方法 |
| CN107802562A (zh) * | 2017-12-17 | 2018-03-16 | 周建福 | 一种洗发膏 |
| GR1010117B (el) | 2020-07-14 | 2021-11-08 | Uni Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε, | Διατροφικο συμπληρωμα για την απο του στοματος χορηγηση συνδυασμου διυδρομυρισετινης, χολινης και μιας ή περισσοτερων βιταμινων με αντιοξειδωτικη δραση, χρησιμων για τη φυσιολογικη λειτουργια του ηπατος |
| DE102020213959A1 (de) * | 2020-11-06 | 2022-05-12 | Beiersdorf Aktiengesellschaft | Verwendung von Dihydromyricetin als epigenetischer Wirkstoff zur kosmetischen oder dermatologischen Hautpflege |
| JP7606737B2 (ja) | 2020-12-09 | 2024-12-26 | 日本メナード化粧品株式会社 | 筋肉疲労改善剤 |
| US12194021B2 (en) | 2021-05-24 | 2025-01-14 | University Of Southern California | Modified herbal compositions for neuromodulation |
| KR102713600B1 (ko) * | 2021-09-17 | 2024-10-07 | 주식회사 인트론바이오테크놀로지 | 보툴리눔 신경독소 대체 신규소재 및 이의 제조방법 |
| CN114507205A (zh) * | 2022-04-19 | 2022-05-17 | 北京佳福瑞生物科技有限公司 | 二氢杨梅素四氢吡咯复合物及其制备方法和应用 |
| CN115177612A (zh) * | 2022-08-01 | 2022-10-14 | 杭州凤禾植物科技有限公司 | 一种具有增发作用的组合物 |
| CN115317392B (zh) * | 2022-08-23 | 2023-10-24 | 广东领康日用品有限公司 | 一种控油去屑氨基酸洗发水及其制备方法 |
| CN117243862A (zh) * | 2023-08-09 | 2023-12-19 | 科丝美诗(中国)化妆品有限公司 | 一种莓茶提取物的制备方法、莓茶提取物及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63208506A (ja) * | 1987-02-24 | 1988-08-30 | Nonogawa Shoji:Kk | 化粧料 |
| JP3597210B2 (ja) | 1993-08-27 | 2004-12-02 | 花王株式会社 | 養毛料 |
| JP5201771B2 (ja) | 2001-04-06 | 2013-06-05 | 丸善製薬株式会社 | テストステロン５α−レダクターゼ阻害剤、アンドロゲン受容体結合阻害剤、抗男性ホルモン剤及び養毛化粧料。 |
| JP5614910B2 (ja) | 2001-07-09 | 2014-10-29 | 丸善製薬株式会社 | 薬剤性肝炎治療剤 |
| JP2004269430A (ja) * | 2003-03-10 | 2004-09-30 | Ichimaru Pharcos Co Ltd | 毛髪処理用組成物及び損傷毛用毛髪化粧料 |
| WO2009052518A2 (en) | 2007-10-19 | 2009-04-23 | Aspen Benefits Group, Llc | Methods and compositions directed to reduction of facial hair hirsutism in females |
| CN101485655B (zh) * | 2009-02-12 | 2012-08-22 | 华南理工大学 | 二氢杨梅素在制备防治肿瘤放化疗不良反应的药物的应用 |
| DE102009055916A1 (de) * | 2009-11-27 | 2011-06-01 | Beiersdorf Ag | Verwendung von Dihydromyricetin gegen Altershaut |
| US8309142B1 (en) * | 2010-06-11 | 2012-11-13 | RMV Trademarks, LLC | Formulations and methods for preventing eyebrow hair loss |
| CN102225923A (zh) * | 2011-04-14 | 2011-10-26 | 湖南朗林生物制品有限公司 | 藤茶中二氢杨梅素的制备方法 |
| US9789047B2 (en) | 2012-07-13 | 2017-10-17 | Phyto Tech Corp. | Treating hair loss and delaying aging of skin |
-
2013
- 2013-07-12 US US14/414,428 patent/US9789047B2/en not_active Expired - Fee Related
- 2013-07-12 WO PCT/US2013/050399 patent/WO2014012075A2/en not_active Ceased
- 2013-07-12 MX MX2015000365A patent/MX362488B/es active IP Right Grant
- 2013-07-12 JP JP2015521871A patent/JP2015522083A/ja active Pending
- 2013-07-12 CN CN201380046985.5A patent/CN104797250A/zh active Pending
- 2013-07-12 HU HUE13817337 patent/HUE044816T2/hu unknown
- 2013-07-12 AU AU2013289963A patent/AU2013289963B2/en not_active Ceased
- 2013-07-12 EP EP13817337.2A patent/EP2872133B1/en active Active
- 2013-07-12 CA CA2878914A patent/CA2878914A1/en not_active Abandoned
- 2013-07-12 ES ES13817337T patent/ES2733351T3/es active Active
- 2013-07-15 TW TW102125290A patent/TWI669116B/zh active
-
2016
- 2016-08-31 US US15/252,849 patent/US9949912B2/en active Active
-
2017
- 2017-04-07 US US15/481,492 patent/US10426718B2/en active Active
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