JP2015520165A5 - - Google Patents
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- JP2015520165A5 JP2015520165A5 JP2015512903A JP2015512903A JP2015520165A5 JP 2015520165 A5 JP2015520165 A5 JP 2015520165A5 JP 2015512903 A JP2015512903 A JP 2015512903A JP 2015512903 A JP2015512903 A JP 2015512903A JP 2015520165 A5 JP2015520165 A5 JP 2015520165A5
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- JP
- Japan
- Prior art keywords
- salt
- compound
- formula
- process according
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261648534P | 2012-05-17 | 2012-05-17 | |
| US61/648,534 | 2012-05-17 | ||
| PCT/US2013/041687 WO2013173779A1 (en) | 2012-05-17 | 2013-05-17 | Process for making amino acid compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015520165A JP2015520165A (ja) | 2015-07-16 |
| JP2015520165A5 true JP2015520165A5 (cg-RX-API-DMAC7.html) | 2016-06-30 |
| JP6196294B2 JP6196294B2 (ja) | 2017-09-13 |
Family
ID=48483247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512903A Active JP6196294B2 (ja) | 2012-05-17 | 2013-05-17 | アミノ酸化合物を製造するためのプロセス |
Country Status (21)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2861582T3 (pl) | 2012-05-17 | 2016-11-30 | Sposób wytwarzania hydroksylowanych związków cyklopentylopirymidynowych | |
| KR102123131B1 (ko) | 2012-05-17 | 2020-06-15 | 제넨테크, 인크. | 하이드록실화 사이클로펜타피리미딘 화합물 및 이의 염의 제조 방법 |
| CA2873663C (en) | 2012-05-17 | 2020-01-14 | Genentech, Inc. | Amorphous form of an akt inhibiting pyrimidinyl-cyclopentane compound, compositions and methods thereof |
| MA37649B1 (fr) | 2012-05-17 | 2017-03-31 | Array Biopharma Inc | Procédé de fabrication de composés cyclopentylpyrimidines hydroxylées |
| KR102698200B1 (ko) * | 2013-11-15 | 2024-08-26 | 에프. 호프만-라 로슈 아게 | 피리미딘일사이클로펜테인 화합물의 제조 방법 |
| EP3626710B1 (en) | 2014-09-26 | 2022-02-16 | F. Hoffmann-La Roche AG | Process for preparing an intermediate in the synthesis of (cyclopentyl[d]pyrimidin-4-yl)piperazine compounds |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663327A (en) * | 1984-05-23 | 1987-05-05 | Bayer Aktiengesellschaft | 1-heteroaryl-4-aryl-pyrazolin-5-ones |
| CA2178829A1 (en) | 1993-12-12 | 1995-06-15 | Yigal Cohen | A novel method to protect plants from fungal infection |
| WO1998044797A1 (en) | 1997-04-07 | 1998-10-15 | Merck & Co., Inc. | A method of treating cancer |
| US6201023B1 (en) | 1997-06-10 | 2001-03-13 | Agrogene Ltd. | Methods and compositions to protect crops against plant parasitic nematodes |
| EP0982300A3 (en) | 1998-07-29 | 2000-03-08 | Societe Civile Bioprojet | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
| JP2003524618A (ja) | 1999-03-03 | 2003-08-19 | メルク エンド カムパニー インコーポレーテッド | プレニル蛋白トランスフェラーゼ阻害剤 |
| WO2001022963A1 (en) | 1999-09-27 | 2001-04-05 | Merck & Co., Inc. | Method of preventing osteoporosis |
| CA2526506A1 (en) | 2003-06-09 | 2004-12-16 | Boehringer Ingelheim International Gmbh | Inhibitors of papilloma virus |
| FR2892416B1 (fr) * | 2005-10-20 | 2008-06-27 | Sanofi Aventis Sa | Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique |
| US8927546B2 (en) | 2006-02-28 | 2015-01-06 | Dart Neuroscience (Cayman) Ltd. | Therapeutic piperazines |
| US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| UA95641C2 (xx) * | 2006-07-06 | 2011-08-25 | Эррей Биофарма Инк. | Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы |
| WO2009047255A1 (en) | 2007-10-09 | 2009-04-16 | Ucb Pharma, S.A. | Heterobicyclic compounds as histamine h4-receptor antagonists |
| CN102459165B (zh) | 2009-04-15 | 2015-09-02 | Abbvie公司 | 抗病毒化合物 |
| US8436002B2 (en) | 2009-10-23 | 2013-05-07 | Eli Lilly And Company | AKT inhibitors |
| EP2592933B1 (en) | 2010-07-16 | 2017-04-05 | Anderson Gaweco | Mif inhibitors and their uses |
| WO2012177925A1 (en) | 2011-06-21 | 2012-12-27 | The Board Institute, Inc. | Akt inhibitors for treating cancer expressing a magi3 - akt3 fusion gene |
| KR102123131B1 (ko) | 2012-05-17 | 2020-06-15 | 제넨테크, 인크. | 하이드록실화 사이클로펜타피리미딘 화합물 및 이의 염의 제조 방법 |
| MA37649B1 (fr) | 2012-05-17 | 2017-03-31 | Array Biopharma Inc | Procédé de fabrication de composés cyclopentylpyrimidines hydroxylées |
| CA2889855A1 (en) | 2012-11-01 | 2014-05-08 | Robert S. Katz | Methods for treating fibromyalgia |
| WO2014127350A1 (en) | 2013-02-18 | 2014-08-21 | The Scripps Research Institute | Modulators of vasopressin receptors with therapeutic potential |
| CN105473141A (zh) | 2013-03-15 | 2016-04-06 | 实发生物医学公司 | 治疗和/或预防心血管疾病的抗pcsk9化合物和方法 |
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2013
- 2013-05-17 NZ NZ702939A patent/NZ702939A/en not_active IP Right Cessation
- 2013-05-17 PL PL13724711T patent/PL2850054T3/pl unknown
- 2013-05-17 KR KR1020147035263A patent/KR102074535B1/ko active Active
- 2013-05-17 WO PCT/US2013/041687 patent/WO2013173779A1/en not_active Ceased
- 2013-05-17 CA CA2873658A patent/CA2873658C/en active Active
- 2013-05-17 EP EP13724711.0A patent/EP2850054B1/en active Active
- 2013-05-17 CN CN201380037572.0A patent/CN104520263B/zh active Active
- 2013-05-17 US US14/401,095 patent/US9278917B2/en active Active
- 2013-05-17 MY MYPI2014703417A patent/MY171538A/en unknown
- 2013-05-17 MX MX2014013863A patent/MX350443B/es active IP Right Grant
- 2013-05-17 SG SG11201407625WA patent/SG11201407625WA/en unknown
- 2013-05-17 JP JP2015512903A patent/JP6196294B2/ja active Active
- 2013-05-17 AU AU2013262516A patent/AU2013262516B2/en active Active
- 2013-05-17 ES ES13724711.0T patent/ES2668477T3/es active Active
- 2013-05-17 BR BR112014028585-3A patent/BR112014028585B1/pt active IP Right Grant
- 2013-05-17 RU RU2014150991A patent/RU2643146C2/ru active
- 2013-05-17 HR HRP20180948TT patent/HRP20180948T1/hr unknown
- 2013-05-17 TR TR2018/07444T patent/TR201807444T4/tr unknown
- 2013-05-17 MA MA37751A patent/MA37751B1/fr unknown
- 2013-05-17 SI SI201331043T patent/SI2850054T1/en unknown
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2014
- 2014-11-11 IL IL235630A patent/IL235630A/en active IP Right Grant