PL2850054T3 - Sposób wytwarzania związków aminokwasowych - Google Patents

Sposób wytwarzania związków aminokwasowych

Info

Publication number
PL2850054T3
PL2850054T3 PL13724711T PL13724711T PL2850054T3 PL 2850054 T3 PL2850054 T3 PL 2850054T3 PL 13724711 T PL13724711 T PL 13724711T PL 13724711 T PL13724711 T PL 13724711T PL 2850054 T3 PL2850054 T3 PL 2850054T3
Authority
PL
Poland
Prior art keywords
amino acid
acid compounds
making amino
making
compounds
Prior art date
Application number
PL13724711T
Other languages
English (en)
Polish (pl)
Inventor
Travis Remarchuk
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of PL2850054T3 publication Critical patent/PL2850054T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/04Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/313Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of doubly bound oxygen containing functional groups, e.g. carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30Preparation of optical isomers
    • C07C227/32Preparation of optical isomers by stereospecific synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
PL13724711T 2012-05-17 2013-05-17 Sposób wytwarzania związków aminokwasowych PL2850054T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261648534P 2012-05-17 2012-05-17
PCT/US2013/041687 WO2013173779A1 (en) 2012-05-17 2013-05-17 Process for making amino acid compounds
EP13724711.0A EP2850054B1 (en) 2012-05-17 2013-05-17 Process for making amino acid compounds

Publications (1)

Publication Number Publication Date
PL2850054T3 true PL2850054T3 (pl) 2018-08-31

Family

ID=48483247

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13724711T PL2850054T3 (pl) 2012-05-17 2013-05-17 Sposób wytwarzania związków aminokwasowych

Country Status (21)

Country Link
US (1) US9278917B2 (cg-RX-API-DMAC7.html)
EP (1) EP2850054B1 (cg-RX-API-DMAC7.html)
JP (1) JP6196294B2 (cg-RX-API-DMAC7.html)
KR (1) KR102074535B1 (cg-RX-API-DMAC7.html)
CN (1) CN104520263B (cg-RX-API-DMAC7.html)
AU (1) AU2013262516B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014028585B1 (cg-RX-API-DMAC7.html)
CA (1) CA2873658C (cg-RX-API-DMAC7.html)
ES (1) ES2668477T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20180948T1 (cg-RX-API-DMAC7.html)
IL (1) IL235630A (cg-RX-API-DMAC7.html)
MA (1) MA37751B1 (cg-RX-API-DMAC7.html)
MX (1) MX350443B (cg-RX-API-DMAC7.html)
MY (1) MY171538A (cg-RX-API-DMAC7.html)
NZ (1) NZ702939A (cg-RX-API-DMAC7.html)
PL (1) PL2850054T3 (cg-RX-API-DMAC7.html)
RU (1) RU2643146C2 (cg-RX-API-DMAC7.html)
SG (1) SG11201407625WA (cg-RX-API-DMAC7.html)
SI (1) SI2850054T1 (cg-RX-API-DMAC7.html)
TR (1) TR201807444T4 (cg-RX-API-DMAC7.html)
WO (1) WO2013173779A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2861582T3 (pl) 2012-05-17 2016-11-30 Sposób wytwarzania hydroksylowanych związków cyklopentylopirymidynowych
KR102123131B1 (ko) 2012-05-17 2020-06-15 제넨테크, 인크. 하이드록실화 사이클로펜타피리미딘 화합물 및 이의 염의 제조 방법
CA2873663C (en) 2012-05-17 2020-01-14 Genentech, Inc. Amorphous form of an akt inhibiting pyrimidinyl-cyclopentane compound, compositions and methods thereof
MA37649B1 (fr) 2012-05-17 2017-03-31 Array Biopharma Inc Procédé de fabrication de composés cyclopentylpyrimidines hydroxylées
KR102698200B1 (ko) * 2013-11-15 2024-08-26 에프. 호프만-라 로슈 아게 피리미딘일사이클로펜테인 화합물의 제조 방법
EP3626710B1 (en) 2014-09-26 2022-02-16 F. Hoffmann-La Roche AG Process for preparing an intermediate in the synthesis of (cyclopentyl[d]pyrimidin-4-yl)piperazine compounds

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US4663327A (en) * 1984-05-23 1987-05-05 Bayer Aktiengesellschaft 1-heteroaryl-4-aryl-pyrazolin-5-ones
CA2178829A1 (en) 1993-12-12 1995-06-15 Yigal Cohen A novel method to protect plants from fungal infection
WO1998044797A1 (en) 1997-04-07 1998-10-15 Merck & Co., Inc. A method of treating cancer
US6201023B1 (en) 1997-06-10 2001-03-13 Agrogene Ltd. Methods and compositions to protect crops against plant parasitic nematodes
EP0982300A3 (en) 1998-07-29 2000-03-08 Societe Civile Bioprojet Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications
JP2003524618A (ja) 1999-03-03 2003-08-19 メルク エンド カムパニー インコーポレーテッド プレニル蛋白トランスフェラーゼ阻害剤
WO2001022963A1 (en) 1999-09-27 2001-04-05 Merck & Co., Inc. Method of preventing osteoporosis
CA2526506A1 (en) 2003-06-09 2004-12-16 Boehringer Ingelheim International Gmbh Inhibitors of papilloma virus
FR2892416B1 (fr) * 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
US8063050B2 (en) 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
UA95641C2 (xx) * 2006-07-06 2011-08-25 Эррей Биофарма Инк. Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы
WO2009047255A1 (en) 2007-10-09 2009-04-16 Ucb Pharma, S.A. Heterobicyclic compounds as histamine h4-receptor antagonists
CN102459165B (zh) 2009-04-15 2015-09-02 Abbvie公司 抗病毒化合物
US8436002B2 (en) 2009-10-23 2013-05-07 Eli Lilly And Company AKT inhibitors
EP2592933B1 (en) 2010-07-16 2017-04-05 Anderson Gaweco Mif inhibitors and their uses
WO2012177925A1 (en) 2011-06-21 2012-12-27 The Board Institute, Inc. Akt inhibitors for treating cancer expressing a magi3 - akt3 fusion gene
KR102123131B1 (ko) 2012-05-17 2020-06-15 제넨테크, 인크. 하이드록실화 사이클로펜타피리미딘 화합물 및 이의 염의 제조 방법
MA37649B1 (fr) 2012-05-17 2017-03-31 Array Biopharma Inc Procédé de fabrication de composés cyclopentylpyrimidines hydroxylées
CA2889855A1 (en) 2012-11-01 2014-05-08 Robert S. Katz Methods for treating fibromyalgia
WO2014127350A1 (en) 2013-02-18 2014-08-21 The Scripps Research Institute Modulators of vasopressin receptors with therapeutic potential
CN105473141A (zh) 2013-03-15 2016-04-06 实发生物医学公司 治疗和/或预防心血管疾病的抗pcsk9化合物和方法

Also Published As

Publication number Publication date
CN104520263A (zh) 2015-04-15
TR201807444T4 (tr) 2018-06-21
BR112014028585B1 (pt) 2020-12-22
MX350443B (es) 2017-09-06
SG11201407625WA (en) 2014-12-30
CN104520263B (zh) 2016-11-09
BR112014028585A2 (pt) 2017-06-27
CA2873658A1 (en) 2013-11-21
US9278917B2 (en) 2016-03-08
MA37751B1 (fr) 2018-08-31
BR112014028585A8 (pt) 2020-09-24
KR20150013808A (ko) 2015-02-05
IL235630A (en) 2017-03-30
JP2015520165A (ja) 2015-07-16
JP6196294B2 (ja) 2017-09-13
AU2013262516B2 (en) 2017-10-19
IL235630A0 (en) 2015-02-01
RU2643146C2 (ru) 2018-01-31
WO2013173779A1 (en) 2013-11-21
ES2668477T3 (es) 2018-05-18
SI2850054T1 (en) 2018-06-29
AU2013262516A1 (en) 2015-01-22
EP2850054A1 (en) 2015-03-25
MA37751A1 (fr) 2018-01-31
MY171538A (en) 2019-10-17
RU2014150991A (ru) 2016-07-10
NZ702939A (en) 2016-08-26
EP2850054B1 (en) 2018-03-21
CA2873658C (en) 2021-01-26
MX2014013863A (es) 2015-05-07
HRP20180948T1 (hr) 2018-08-10
US20150148559A1 (en) 2015-05-28
HK1208857A1 (en) 2016-03-18
KR102074535B1 (ko) 2020-02-06

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