JP2015518837A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015518837A5 JP2015518837A5 JP2015512890A JP2015512890A JP2015518837A5 JP 2015518837 A5 JP2015518837 A5 JP 2015518837A5 JP 2015512890 A JP2015512890 A JP 2015512890A JP 2015512890 A JP2015512890 A JP 2015512890A JP 2015518837 A5 JP2015518837 A5 JP 2015518837A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- salt
- formula
- process according
- forming
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C[C@](C*)c(c(Cl)ncn1)c1Cl Chemical compound C[C@](C*)c(c(Cl)ncn1)c1Cl 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261648421P | 2012-05-17 | 2012-05-17 | |
| US61/648,421 | 2012-05-17 | ||
| US201361785281P | 2013-03-14 | 2013-03-14 | |
| US61/785,281 | 2013-03-14 | ||
| PCT/US2013/041624 WO2013173736A1 (en) | 2012-05-17 | 2013-05-17 | Process for making hydroxylated cyclopentylpyrimidine compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015518837A JP2015518837A (ja) | 2015-07-06 |
| JP2015518837A5 true JP2015518837A5 (enExample) | 2016-07-07 |
| JP6214636B2 JP6214636B2 (ja) | 2017-10-18 |
Family
ID=48534507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512890A Active JP6214636B2 (ja) | 2012-05-17 | 2013-05-17 | ヒドロキシル化シクロペンチルピリミジン化合物を作製するためのプロセス |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9309204B2 (enExample) |
| EP (1) | EP2861583B1 (enExample) |
| JP (1) | JP6214636B2 (enExample) |
| KR (1) | KR20150020211A (enExample) |
| CN (1) | CN104487430B (enExample) |
| AU (1) | AU2013262568B2 (enExample) |
| BR (1) | BR112014028570A2 (enExample) |
| CA (1) | CA2873653A1 (enExample) |
| DK (1) | DK2861583T3 (enExample) |
| ES (1) | ES2588878T3 (enExample) |
| IL (1) | IL235714A0 (enExample) |
| MA (1) | MA37649B1 (enExample) |
| MX (1) | MX2014013865A (enExample) |
| PL (1) | PL2861583T3 (enExample) |
| RU (1) | RU2014151017A (enExample) |
| SG (1) | SG11201407613RA (enExample) |
| SI (1) | SI2861583T1 (enExample) |
| WO (1) | WO2013173736A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6284928B2 (ja) | 2012-05-17 | 2018-02-28 | アレイ バイオファーマ、インコーポレイテッド | ヒドロキシル化シクロペンチルピリミジン化合物を作製するためのプロセス |
| NZ702939A (en) | 2012-05-17 | 2016-08-26 | Genentech Inc | Process for making amino acid compounds |
| MX354373B (es) | 2012-05-17 | 2018-02-28 | Genentech Inc | Proceso para hacer compuestos de ciclopentapirimidina hidroxilada y sus sales. |
| RS60417B9 (sr) | 2012-05-17 | 2021-07-30 | Genentech Inc | Amorfni oblik aktivnog jedinjenja koje inhibira pirimidinil-ciklopentansko jedinjenje, smeše i njegove metode |
| SG10201901578UA (en) | 2013-11-15 | 2019-03-28 | Hoffmann La Roche | Processes for the preparation of pyrimidinylcyclopentane compounds |
| ES2688600T3 (es) * | 2013-11-27 | 2018-11-05 | Sunshine Lake Pharma Co., Ltd. | Procesos para preparar derivados de dihidropirimidina e intermedios de los mismos |
| US10457648B2 (en) * | 2014-09-26 | 2019-10-29 | Genentech Inc. | Process for preparing (cyclopentyl[d]pyrimidin-4-yl)piperazine compounds |
| IL295929A (en) | 2020-06-16 | 2022-10-01 | Hoffmann La Roche | Process for making hydroxylated cyclopentylpyrimidine compounds |
| KR102689151B1 (ko) * | 2021-09-06 | 2024-07-29 | 연세대학교 산학협력단 | Akt 신호경로 억제제를 유효성분으로 포함하는 아토피피부염의 예방 또는 치료용 조성물 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU700579B2 (en) | 1993-12-12 | 1999-01-07 | Agrogene Ltd | A novel method to protect plants from fungal infection |
| CA2286239A1 (en) | 1997-04-07 | 1998-10-15 | Merck & Co., Inc. | A method of treating cancer |
| US6201023B1 (en) | 1997-06-10 | 2001-03-13 | Agrogene Ltd. | Methods and compositions to protect crops against plant parasitic nematodes |
| EP0982300A3 (en) | 1998-07-29 | 2000-03-08 | Societe Civile Bioprojet | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
| JP2003524618A (ja) | 1999-03-03 | 2003-08-19 | メルク エンド カムパニー インコーポレーテッド | プレニル蛋白トランスフェラーゼ阻害剤 |
| CN1281604C (zh) | 1999-06-03 | 2006-10-25 | 帝国脏器制药株式会社 | 取代吡唑化合物 |
| WO2001022963A1 (en) | 1999-09-27 | 2001-04-05 | Merck & Co., Inc. | Method of preventing osteoporosis |
| EP1636200A2 (en) | 2003-06-09 | 2006-03-22 | Boehringer Ingelheim International GmbH | Inhibitors of papilloma virus |
| EP1684694A2 (en) | 2003-11-21 | 2006-08-02 | Array Biopharma, Inc. | Akt protein kinase inhibitors |
| US8927546B2 (en) | 2006-02-28 | 2015-01-06 | Dart Neuroscience (Cayman) Ltd. | Therapeutic piperazines |
| US8063050B2 (en) * | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| UA95641C2 (xx) | 2006-07-06 | 2011-08-25 | Эррей Биофарма Инк. | Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы |
| JP5157576B2 (ja) | 2007-05-14 | 2013-03-06 | 住友化学株式会社 | 光学活性２−アルキル−１，１，３−トリアルコキシカルボニルプロパンの製造方法 |
| ES2533557T3 (es) * | 2007-07-05 | 2015-04-13 | Array Biopharma, Inc. | Pirimidil ciclopentanos como inhibidores de proteína cinasa AKT |
| US20100298289A1 (en) | 2007-10-09 | 2010-11-25 | Ucb Pharma, S.A. | Heterobicyclic compounds as histamine h4-receptor antagonists |
| WO2009089459A1 (en) * | 2008-01-09 | 2009-07-16 | Array Biopharma Inc. | Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors |
| JP5551707B2 (ja) * | 2008-10-15 | 2014-07-16 | アムジエン・インコーポレーテツド | スピロ環ｇｐｒ４０調節因子 |
| RU2541571C2 (ru) | 2009-04-15 | 2015-02-20 | Эббви Инк. | Противовирусные соединения |
| EA020151B1 (ru) * | 2009-10-23 | 2014-09-30 | Эли Лилли Энд Компани | Ингибиторы akt и фармацевтические составы, их содержащие |
| WO2012009649A1 (en) | 2010-07-16 | 2012-01-19 | Anderson Gaweco | Mif inhibitors and their uses |
| WO2012177925A1 (en) | 2011-06-21 | 2012-12-27 | The Board Institute, Inc. | Akt inhibitors for treating cancer expressing a magi3 - akt3 fusion gene |
| MX354373B (es) | 2012-05-17 | 2018-02-28 | Genentech Inc | Proceso para hacer compuestos de ciclopentapirimidina hidroxilada y sus sales. |
| NZ702939A (en) | 2012-05-17 | 2016-08-26 | Genentech Inc | Process for making amino acid compounds |
| JP6284928B2 (ja) | 2012-05-17 | 2018-02-28 | アレイ バイオファーマ、インコーポレイテッド | ヒドロキシル化シクロペンチルピリミジン化合物を作製するためのプロセス |
| WO2014071194A2 (en) | 2012-11-01 | 2014-05-08 | Katz Robert S | Methods for treating fibromyalgia |
| JP2016513112A (ja) | 2013-02-18 | 2016-05-12 | ザ スクリプス リサーチ インスティテュート | 治療的潜在能力を有するバソプレッシン受容体のモジュレーター |
| AU2014237198A1 (en) | 2013-03-15 | 2015-11-05 | Shifa Biomedical Corporation | Anti-PCSK9 compounds and methods for the treatment and/or prevention of cardiovascular diseases |
-
2013
- 2013-05-17 DK DK13725533.7T patent/DK2861583T3/en active
- 2013-05-17 SG SG11201407613RA patent/SG11201407613RA/en unknown
- 2013-05-17 ES ES13725533.7T patent/ES2588878T3/es active Active
- 2013-05-17 CN CN201380037994.8A patent/CN104487430B/zh active Active
- 2013-05-17 EP EP13725533.7A patent/EP2861583B1/en active Active
- 2013-05-17 BR BR112014028570A patent/BR112014028570A2/pt not_active IP Right Cessation
- 2013-05-17 SI SI201330302A patent/SI2861583T1/sl unknown
- 2013-05-17 RU RU2014151017A patent/RU2014151017A/ru not_active Application Discontinuation
- 2013-05-17 MX MX2014013865A patent/MX2014013865A/es unknown
- 2013-05-17 WO PCT/US2013/041624 patent/WO2013173736A1/en not_active Ceased
- 2013-05-17 US US14/401,091 patent/US9309204B2/en active Active
- 2013-05-17 CA CA2873653A patent/CA2873653A1/en not_active Abandoned
- 2013-05-17 JP JP2015512890A patent/JP6214636B2/ja active Active
- 2013-05-17 PL PL13725533.7T patent/PL2861583T3/pl unknown
- 2013-05-17 MA MA37649A patent/MA37649B1/fr unknown
- 2013-05-17 AU AU2013262568A patent/AU2013262568B2/en not_active Ceased
- 2013-05-17 KR KR20147035262A patent/KR20150020211A/ko not_active Withdrawn
-
2014
- 2014-11-13 IL IL235714A patent/IL235714A0/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015518837A5 (enExample) | ||
| RU2014151017A (ru) | Способ получения гидроксилированных циклопентилпиримидинов | |
| JP2012506425A5 (enExample) | ||
| JP2011121989A5 (enExample) | ||
| JP2014511367A5 (enExample) | ||
| JP2013147496A5 (ja) | 有機金属錯体 | |
| JP2015516945A5 (enExample) | ||
| JP2013521295A5 (enExample) | ||
| JP2012092103A5 (enExample) | ||
| JP2015512868A5 (ja) | ビニルエステル及び酢酸又はプロピオン酸反応生成物の共製造の第一段階としてのトランスビニル化 | |
| IL229800A (en) | Method of production of bicyclic compound by iminium salt | |
| BR112018004447A2 (pt) | derivado de biarila e medicamento contendo o mesmo | |
| WO2012166754A3 (en) | Method for avoiding the generation of by-products during the production of haloalkane compounds | |
| RU2019119584A (ru) | Способ получения триазолопиридинового соединения | |
| JP2013531058A5 (enExample) | ||
| JP2017509581A5 (enExample) | ||
| JP2016535033A5 (enExample) | ||
| CU24173B1 (es) | Compuestos derivados de tieno [2,3-d] pirimidina para el tratamiento de la arritmia | |
| JP2013241421A5 (enExample) | ||
| HRP20191632T1 (hr) | Kemijski postupak dobivanja spiroindolona i njihovih međuprodukata | |
| IN2013MN02407A (enExample) | ||
| JP2014508714A5 (enExample) | ||
| JP2016040296A5 (enExample) | ||
| RU2015118152A (ru) | Новое сложноэфирное соединение алициклической дикарбоновой кислоты и способ его изготовления | |
| RU2016112136A (ru) | Способ получения 1,1-дибром-1-фторэтана |