JP2015518724A5 - - Google Patents
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- JP2015518724A5 JP2015518724A5 JP2015514143A JP2015514143A JP2015518724A5 JP 2015518724 A5 JP2015518724 A5 JP 2015518724A5 JP 2015514143 A JP2015514143 A JP 2015514143A JP 2015514143 A JP2015514143 A JP 2015514143A JP 2015518724 A5 JP2015518724 A5 JP 2015518724A5
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- breast cancer
- expression
- luminal
- her2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 230000014509 gene expression Effects 0.000 claims description 24
- 206010028980 Neoplasm Diseases 0.000 claims description 20
- 108090000623 proteins and genes Proteins 0.000 claims description 16
- 206010006187 Breast cancer Diseases 0.000 claims description 13
- 208000026310 Breast neoplasm Diseases 0.000 claims description 13
- 239000000523 sample Substances 0.000 claims description 12
- 230000012010 growth Effects 0.000 claims description 3
- 230000035755 proliferation Effects 0.000 claims description 3
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 claims 9
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 claims 9
- 102100038595 Estrogen receptor Human genes 0.000 claims 5
- 101000837581 Homo sapiens Ubiquitin-conjugating enzyme E2 T Proteins 0.000 claims 5
- 102100028705 Ubiquitin-conjugating enzyme E2 T Human genes 0.000 claims 5
- 102000003998 progesterone receptors Human genes 0.000 claims 5
- 108090000468 progesterone receptors Proteins 0.000 claims 5
- KIAPWMKFHIKQOZ-UHFFFAOYSA-N 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester Chemical compound COC(=O)C1=CC=CC=C1NC(=O)C1=CC=C(F)C=C1 KIAPWMKFHIKQOZ-UHFFFAOYSA-N 0.000 claims 3
- 102100033393 Anillin Human genes 0.000 claims 3
- 108700020472 CDC20 Proteins 0.000 claims 3
- 101150023302 Cdc20 gene Proteins 0.000 claims 3
- 102100027047 Cell division control protein 6 homolog Human genes 0.000 claims 3
- 102100038099 Cell division cycle protein 20 homolog Human genes 0.000 claims 3
- 102100023344 Centromere protein F Human genes 0.000 claims 3
- 101710092479 Centrosomal protein of 55 kDa Proteins 0.000 claims 3
- 102100031219 Centrosomal protein of 55 kDa Human genes 0.000 claims 3
- 102100029075 Exonuclease 1 Human genes 0.000 claims 3
- 102100037858 G1/S-specific cyclin-E1 Human genes 0.000 claims 3
- 101000732632 Homo sapiens Anillin Proteins 0.000 claims 3
- 101000914465 Homo sapiens Cell division control protein 6 homolog Proteins 0.000 claims 3
- 101000907941 Homo sapiens Centromere protein F Proteins 0.000 claims 3
- 101000918264 Homo sapiens Exonuclease 1 Proteins 0.000 claims 3
- 101000738568 Homo sapiens G1/S-specific cyclin-E1 Proteins 0.000 claims 3
- 101001050567 Homo sapiens Kinesin-like protein KIF2C Proteins 0.000 claims 3
- 101001112162 Homo sapiens Kinetochore protein NDC80 homolog Proteins 0.000 claims 3
- 101000590482 Homo sapiens Kinetochore protein Nuf2 Proteins 0.000 claims 3
- 101000721146 Homo sapiens Origin recognition complex subunit 6 Proteins 0.000 claims 3
- 101000945496 Homo sapiens Proliferation marker protein Ki-67 Proteins 0.000 claims 3
- 101000575639 Homo sapiens Ribonucleoside-diphosphate reductase subunit M2 Proteins 0.000 claims 3
- 101001087372 Homo sapiens Securin Proteins 0.000 claims 3
- 101000809797 Homo sapiens Thymidylate synthase Proteins 0.000 claims 3
- 101000807354 Homo sapiens Ubiquitin-conjugating enzyme E2 C Proteins 0.000 claims 3
- 102100023424 Kinesin-like protein KIF2C Human genes 0.000 claims 3
- 102100023890 Kinetochore protein NDC80 homolog Human genes 0.000 claims 3
- 102100032431 Kinetochore protein Nuf2 Human genes 0.000 claims 3
- 102100024299 Maternal embryonic leucine zipper kinase Human genes 0.000 claims 3
- 101710154611 Maternal embryonic leucine zipper kinase Proteins 0.000 claims 3
- 102100025201 Origin recognition complex subunit 6 Human genes 0.000 claims 3
- 102100034836 Proliferation marker protein Ki-67 Human genes 0.000 claims 3
- 102100026006 Ribonucleoside-diphosphate reductase subunit M2 Human genes 0.000 claims 3
- 101100010298 Schizosaccharomyces pombe (strain 972 / ATCC 24843) pol2 gene Proteins 0.000 claims 3
- 102100033004 Securin Human genes 0.000 claims 3
- 102100038618 Thymidylate synthase Human genes 0.000 claims 3
- 102100037256 Ubiquitin-conjugating enzyme E2 C Human genes 0.000 claims 3
- 108010038795 estrogen receptors Proteins 0.000 claims 3
- 208000026535 luminal A breast carcinoma Diseases 0.000 claims 3
- 208000026534 luminal B breast carcinoma Diseases 0.000 claims 3
- WVAKRQOMAINQPU-UHFFFAOYSA-N 2-[4-[2-[5-(2,2-dimethylbutyl)-1h-imidazol-2-yl]ethyl]phenyl]pyridine Chemical compound N1C(CC(C)(C)CC)=CN=C1CCC1=CC=C(C=2N=CC=CC=2)C=C1 WVAKRQOMAINQPU-UHFFFAOYSA-N 0.000 claims 2
- 102100029631 Actin-related protein 3B Human genes 0.000 claims 2
- 102100021569 Apoptosis regulator Bcl-2 Human genes 0.000 claims 2
- 102100037152 BAG family molecular chaperone regulator 1 Human genes 0.000 claims 2
- 108091012583 BCL2 Proteins 0.000 claims 2
- 102100035752 Biliverdin reductase A Human genes 0.000 claims 2
- 102100036167 CXXC-type zinc finger protein 5 Human genes 0.000 claims 2
- 102100024153 Cadherin-15 Human genes 0.000 claims 2
- 101001030219 Drosophila melanogaster Unconventional myosin ID Proteins 0.000 claims 2
- 108050002772 E3 ubiquitin-protein ligase Mdm2 Proteins 0.000 claims 2
- 102000012199 E3 ubiquitin-protein ligase Mdm2 Human genes 0.000 claims 2
- 101150029707 ERBB2 gene Proteins 0.000 claims 2
- 102100027844 Fibroblast growth factor receptor 4 Human genes 0.000 claims 2
- 102100021084 Forkhead box protein C1 Human genes 0.000 claims 2
- 102100029283 Hepatocyte nuclear factor 3-alpha Human genes 0.000 claims 2
- 101000728742 Homo sapiens Actin-related protein 3B Proteins 0.000 claims 2
- 101000884385 Homo sapiens Arylamine N-acetyltransferase 1 Proteins 0.000 claims 2
- 101000740062 Homo sapiens BAG family molecular chaperone regulator 1 Proteins 0.000 claims 2
- 101000802825 Homo sapiens Biliverdin reductase A Proteins 0.000 claims 2
- 101000947154 Homo sapiens CXXC-type zinc finger protein 5 Proteins 0.000 claims 2
- 101000762242 Homo sapiens Cadherin-15 Proteins 0.000 claims 2
- 101000714553 Homo sapiens Cadherin-3 Proteins 0.000 claims 2
- 101000882584 Homo sapiens Estrogen receptor Proteins 0.000 claims 2
- 101001034811 Homo sapiens Eukaryotic translation initiation factor 4 gamma 2 Proteins 0.000 claims 2
- 101000917134 Homo sapiens Fibroblast growth factor receptor 4 Proteins 0.000 claims 2
- 101000818310 Homo sapiens Forkhead box protein C1 Proteins 0.000 claims 2
- 101001062353 Homo sapiens Hepatocyte nuclear factor 3-alpha Proteins 0.000 claims 2
- 101000614436 Homo sapiens Keratin, type I cytoskeletal 14 Proteins 0.000 claims 2
- 101000998027 Homo sapiens Keratin, type I cytoskeletal 17 Proteins 0.000 claims 2
- 101001056473 Homo sapiens Keratin, type II cytoskeletal 5 Proteins 0.000 claims 2
- 101000973510 Homo sapiens Melanoma-derived growth regulatory protein Proteins 0.000 claims 2
- 101001055386 Homo sapiens Melanophilin Proteins 0.000 claims 2
- 101000891579 Homo sapiens Microtubule-associated protein tau Proteins 0.000 claims 2
- 101001030211 Homo sapiens Myc proto-oncogene protein Proteins 0.000 claims 2
- 101000857740 Homo sapiens Probable G-protein coupled receptor 160 Proteins 0.000 claims 2
- 101000864743 Homo sapiens Secreted frizzled-related protein 1 Proteins 0.000 claims 2
- 101000639975 Homo sapiens Sodium-dependent noradrenaline transporter Proteins 0.000 claims 2
- 101000831862 Homo sapiens Transmembrane protein 45B Proteins 0.000 claims 2
- 102100040445 Keratin, type I cytoskeletal 14 Human genes 0.000 claims 2
- 102100033511 Keratin, type I cytoskeletal 17 Human genes 0.000 claims 2
- 102100025756 Keratin, type II cytoskeletal 5 Human genes 0.000 claims 2
- 102100022185 Melanoma-derived growth regulatory protein Human genes 0.000 claims 2
- 102100026158 Melanophilin Human genes 0.000 claims 2
- 102100040243 Microtubule-associated protein tau Human genes 0.000 claims 2
- 102100038895 Myc proto-oncogene protein Human genes 0.000 claims 2
- 102100025346 Probable G-protein coupled receptor 160 Human genes 0.000 claims 2
- 108091006938 SLC39A6 Proteins 0.000 claims 2
- 102100030058 Secreted frizzled-related protein 1 Human genes 0.000 claims 2
- 102100033929 Sodium-dependent noradrenaline transporter Human genes 0.000 claims 2
- 102100024181 Transmembrane protein 45B Human genes 0.000 claims 2
- 102100023144 Zinc transporter ZIP6 Human genes 0.000 claims 2
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 claims 2
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 claims 2
- 239000000178 monomer Substances 0.000 claims 2
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 230000004083 survival effect Effects 0.000 claims 2
- 230000004614 tumor growth Effects 0.000 claims 2
- 102100037579 D-3-phosphoglycerate dehydrogenase Human genes 0.000 claims 1
- 101000739890 Homo sapiens D-3-phosphoglycerate dehydrogenase Proteins 0.000 claims 1
- 101000577877 Homo sapiens Stromelysin-3 Proteins 0.000 claims 1
- 102100028847 Stromelysin-3 Human genes 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 230000004797 therapeutic response Effects 0.000 claims 1
- 239000012472 biological sample Substances 0.000 description 3
- 238000004364 calculation method Methods 0.000 description 2
- 102100032340 G2/mitotic-specific cyclin-B1 Human genes 0.000 description 1
- 108700031843 GRB7 Adaptor Proteins 0.000 description 1
- 101150052409 GRB7 gene Proteins 0.000 description 1
- 102100033107 Growth factor receptor-bound protein 7 Human genes 0.000 description 1
- 101000868643 Homo sapiens G2/mitotic-specific cyclin-B1 Proteins 0.000 description 1
- 101000593405 Homo sapiens Myb-related protein B Proteins 0.000 description 1
- 102100034670 Myb-related protein B Human genes 0.000 description 1
- 108010002687 Survivin Proteins 0.000 description 1
- 102000000763 Survivin Human genes 0.000 description 1
- 238000004422 calculation algorithm Methods 0.000 description 1
- 239000013074 reference sample Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261650209P | 2012-05-22 | 2012-05-22 | |
| US61/650,209 | 2012-05-22 | ||
| US201361753673P | 2013-01-17 | 2013-01-17 | |
| US61/753,673 | 2013-01-17 | ||
| PCT/US2013/042157 WO2013177245A2 (en) | 2012-05-22 | 2013-05-22 | Nano46 genes and methods to predict breast cancer outcome |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015518724A JP2015518724A (ja) | 2015-07-06 |
| JP2015518724A5 true JP2015518724A5 (enExample) | 2017-12-28 |
| JP6325530B2 JP6325530B2 (ja) | 2018-05-16 |
Family
ID=49624503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015514143A Active JP6325530B2 (ja) | 2012-05-22 | 2013-05-22 | Ｎａｎｏ４６遺伝子、及び乳癌転帰を予測する方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20130337444A1 (enExample) |
| EP (1) | EP2852689B1 (enExample) |
| JP (1) | JP6325530B2 (enExample) |
| CN (2) | CN104704128A (enExample) |
| AU (1) | AU2013266419B2 (enExample) |
| BR (1) | BR112014029300A2 (enExample) |
| CA (1) | CA2874492C (enExample) |
| ES (1) | ES2763931T3 (enExample) |
| IL (1) | IL235795B (enExample) |
| IN (1) | IN2014MN02418A (enExample) |
| MX (1) | MX369628B (enExample) |
| WO (1) | WO2013177245A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9631239B2 (en) | 2008-05-30 | 2017-04-25 | University Of Utah Research Foundation | Method of classifying a breast cancer instrinsic subtype |
| EP2685988A4 (en) | 2011-03-15 | 2014-08-20 | Univ North Carolina | Methods of treating breast cancer with anthracycline therapy |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| AU2012345789B2 (en) | 2011-11-30 | 2018-02-15 | British Columbia Cancer Agency Branch | Methods of treating breast cancer with taxane therapy |
| EP3511423B2 (en) | 2012-10-17 | 2024-05-29 | Spatial Transcriptomics AB | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| HK1222888A1 (zh) * | 2013-05-13 | 2017-07-14 | Nanostring Technologies, Inc. | 预测在淋巴结阳性早期乳癌复发风险的方法 |
| LT3013983T (lt) | 2013-06-25 | 2023-05-10 | Prognosys Biosciences, Inc. | Erdviniai koduoti biologiniai tyrimai, naudojant mikrofluidinį įrenginį |
| AU2014317843A1 (en) | 2013-09-09 | 2016-03-24 | British Columbia Cancer Agency Branch | Methods and kits for predicting outcome and methods and kits for treating breast cancer with radiation therapy |
| EP3221469B1 (en) | 2014-11-21 | 2020-01-15 | Nanostring Technologies, Inc | Enzyme- and amplification-free sequencing |
| AU2015353747B2 (en) * | 2014-11-24 | 2021-02-25 | Bruker Spatial Biology, Inc. | Methods and apparatuses for gene purification and imaging |
| JP2018500895A (ja) * | 2014-12-09 | 2018-01-18 | キングス・カレッジ・ロンドン | タキサン療法による乳癌治療 |
| SG11201707515SA (en) | 2015-04-10 | 2017-10-30 | Spatial Transcriptomics Ab | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| WO2017014694A1 (en) * | 2015-07-23 | 2017-01-26 | National University Of Singapore | Wbp2 as a co-prognostic factor with her2 for stratification of patients for treatment |
| EP4324929B1 (en) | 2016-05-16 | 2025-09-17 | Bruker Spatial Biology, Inc. | Methods for detecting target nucleic acids in a sample |
| EP3472359B1 (en) | 2016-06-21 | 2022-03-16 | 10X Genomics, Inc. | Nucleic acid sequencing |
| WO2018074865A2 (ko) * | 2016-10-21 | 2018-04-26 | 서울대학교병원 | 유방암 예후 예측용 조성물 및 방법 |
| US10415080B2 (en) | 2016-11-21 | 2019-09-17 | Nanostring Technologies, Inc. | Chemical compositions and methods of using same |
| KR101950717B1 (ko) * | 2016-11-23 | 2019-02-21 | 주식회사 젠큐릭스 | 유방암 환자의 화학치료 유용성 예측 방법 |
| WO2018144782A1 (en) * | 2017-02-01 | 2018-08-09 | The Translational Genomics Research Institute | Methods of detecting somatic and germline variants in impure tumors |
| CN120210336A (zh) | 2017-10-06 | 2025-06-27 | 10X基因组学有限公司 | Rna模板化连接 |
| KR102071491B1 (ko) * | 2017-11-10 | 2020-01-30 | 주식회사 디시젠 | 차세대 염기서열분석을 이용한 기계학습 기반 유방암 예후 예측 방법 및 예측 시스템 |
| KR102893736B1 (ko) | 2018-05-14 | 2025-11-28 | 브루커 스페이셜 바이올로지, 인크. | 화학 조성물 및 이의 사용 방법 |
| WO2020094399A1 (en) * | 2018-11-05 | 2020-05-14 | Biontech Diagnostics Gmbh | Predictive methods in breast cancer |
| WO2020240025A1 (en) | 2019-05-31 | 2020-12-03 | Cartana Ab | Method of detecting target nucleic acid molecules |
| JP7352937B2 (ja) * | 2019-07-19 | 2023-09-29 | 公立大学法人福島県立医科大学 | 乳癌のサブタイプを鑑別又は分類するための鑑別マーカー遺伝子セット、方法およびキット |
| GB201919032D0 (en) | 2019-12-20 | 2020-02-05 | Cartana Ab | Method of detecting an analyte |
| EP4107285B1 (en) | 2020-02-21 | 2024-10-09 | 10X Genomics, Inc. | Methods and compositions for integrated in situ spatial assay |
| US12209273B2 (en) | 2020-06-12 | 2025-01-28 | 10X Genomics, Inc. | Nucleic acid assays using click chemistry bioconjugation |
| EP3945136A1 (en) * | 2020-07-28 | 2022-02-02 | Hospital Clínic de Barcelona | In vitro method for the prognosis of patients suffering from her2-positive breast cancer |
| US12297499B2 (en) | 2020-08-17 | 2025-05-13 | 10X Genomics, Inc. | Multicomponent nucleic acid probes for sample analysis |
| US12060603B2 (en) | 2021-01-19 | 2024-08-13 | 10X Genomics, Inc. | Methods for internally controlled in situ assays using padlock probes |
| CA3248919A1 (en) * | 2021-12-20 | 2023-06-29 | Fundacio De Recerca Clinic Barcelona-Institut D’Investigacions Biomèdiques August Pi I Sunyer | DEVELOPMENT AND VALIDATION OF AN IN VITRO PROGNOSIS FOR PATIENTS WITH HER2-POSITIVE BREAST CANCER |
| CN117965734B (zh) * | 2024-02-02 | 2024-09-24 | 奥明星程(杭州)生物科技有限公司 | 一种用于检测硬纤维瘤的基因标志物、试剂盒、检测方法及应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6040138A (en) | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| EP0773227A1 (en) | 1991-09-18 | 1997-05-14 | Affymax Technologies N.V. | Diverse collections of oligomers in use to prepare drugs, diagnostic reagents, pesticides or herbicides |
| EP0916396B1 (en) | 1991-11-22 | 2005-04-13 | Affymetrix, Inc. (a Delaware Corporation) | Combinatorial strategies for polymer synthesis |
| US5384261A (en) | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
| US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
| EP0880598A4 (en) | 1996-01-23 | 2005-02-23 | Affymetrix Inc | RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM |
| JP2001521753A (ja) | 1997-10-31 | 2001-11-13 | アフィメトリックス インコーポレイテッド | 成人臓器及び胎児臓器中の発現プロフィール |
| US6020135A (en) | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
| US6750015B2 (en) * | 2000-06-28 | 2004-06-15 | Kathryn B. Horwitz | Progesterone receptor-regulated gene expression and methods related thereto |
| US20020168639A1 (en) * | 2000-09-22 | 2002-11-14 | Muraca Patrick J. | Profile array substrates |
| DK3170906T3 (en) | 2003-06-24 | 2018-11-05 | Genomic Health Inc | PREDICTION OF THE LIKELI REVENUE OF CANCER |
| AU2004285103A1 (en) * | 2003-09-29 | 2005-05-12 | Pathwork Diagnostics, Inc. | Systems and methods for detecting biological features |
| WO2006010150A2 (en) | 2004-07-15 | 2006-01-26 | University Of Utah Research Foundation | Housekeeping genes and methods for identifying the same |
| CN101057144A (zh) * | 2004-09-22 | 2007-10-17 | 三路影像公司 | 用于评价乳腺癌预后的方法和组合物 |
| US20090299640A1 (en) | 2005-11-23 | 2009-12-03 | University Of Utah Research Foundation | Methods and Compositions Involving Intrinsic Genes |
| EP1963500B1 (en) | 2005-12-23 | 2013-02-13 | Nanostring Technologies, Inc. | Compositions comprising oriented, immobilized macromolecules and methods for their preparation |
| AU2006330830B2 (en) * | 2005-12-23 | 2013-01-10 | Bruker Spatial Biology, Inc. | Nanoreporters and methods of manufacturing and use thereof |
| US8415102B2 (en) | 2007-04-10 | 2013-04-09 | Nanostring Technologies, Inc. | Methods and computer systems for identifying target-specific sequences for use in nanoreporters |
| WO2008150512A2 (en) * | 2007-06-04 | 2008-12-11 | University Of Louisville Research Foundation, Inc. | Methods for identifying an increased likelihood of recurrence of breast cancer |
| CN102395682B (zh) * | 2007-09-06 | 2015-09-30 | 生物治疗诊断股份有限公司 | 肿瘤分级和癌症预后 |
| US9631239B2 (en) * | 2008-05-30 | 2017-04-25 | University Of Utah Research Foundation | Method of classifying a breast cancer instrinsic subtype |
| US8519115B2 (en) | 2008-08-14 | 2013-08-27 | Nanostring Technologies, Inc. | Stable nanoreporters |
| JP5940517B2 (ja) * | 2010-03-31 | 2016-06-29 | ジヴィドン ダイアグノスティックス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 内分泌治療下における乳癌再発を予測するための方法 |
-
2013
- 2013-05-22 IN IN2418MUN2014 patent/IN2014MN02418A/en unknown
- 2013-05-22 ES ES13794236T patent/ES2763931T3/es active Active
- 2013-05-22 WO PCT/US2013/042157 patent/WO2013177245A2/en not_active Ceased
- 2013-05-22 JP JP2015514143A patent/JP6325530B2/ja active Active
- 2013-05-22 AU AU2013266419A patent/AU2013266419B2/en active Active
- 2013-05-22 BR BR112014029300A patent/BR112014029300A2/pt not_active Application Discontinuation
- 2013-05-22 CN CN201380038875.4A patent/CN104704128A/zh active Pending
- 2013-05-22 EP EP13794236.3A patent/EP2852689B1/en active Active
- 2013-05-22 CN CN201911216650.9A patent/CN111500718A/zh active Pending
- 2013-05-22 MX MX2014014275A patent/MX369628B/es active IP Right Grant
- 2013-05-22 US US13/899,656 patent/US20130337444A1/en not_active Abandoned
- 2013-05-22 CA CA2874492A patent/CA2874492C/en active Active
-
2014
- 2014-11-20 IL IL235795A patent/IL235795B/en active IP Right Grant
-
2020
- 2020-02-14 US US16/792,051 patent/US20200332368A1/en not_active Abandoned
-
2022
- 2022-09-29 US US17/936,745 patent/US20230272476A1/en active Pending
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