CN104704128A - 预测乳腺癌结果的nano46基因和方法 - Google Patents

预测乳腺癌结果的nano46基因和方法 Download PDF

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Publication number
CN104704128A
CN104704128A CN201380038875.4A CN201380038875A CN104704128A CN 104704128 A CN104704128 A CN 104704128A CN 201380038875 A CN201380038875 A CN 201380038875A CN 104704128 A CN104704128 A CN 104704128A
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China
Prior art keywords
expression
gene
nano46
breast cancer
genes
Prior art date
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Pending
Application number
CN201380038875.4A
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English (en)
Chinese (zh)
Inventor
S.M.费里
J.J.斯托尔霍夫
J.S.帕克
C.M.佩罗
M.J.艾利斯
P.S.伯纳德
T.O.尼尔森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
British Columbia Cancer Agency BCCA
University of Washington
University of North Carolina at Chapel Hill
University of Utah Research Foundation Inc
NS Wind Down Co Inc
Original Assignee
British Columbia Cancer Agency BCCA
University of Washington
University of North Carolina at Chapel Hill
Nanostring Technologies Inc
University of Utah Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by British Columbia Cancer Agency BCCA, University of Washington, University of North Carolina at Chapel Hill, Nanostring Technologies Inc, University of Utah Research Foundation Inc filed Critical British Columbia Cancer Agency BCCA
Priority to CN201911216650.9A priority Critical patent/CN111500718A/zh
Publication of CN104704128A publication Critical patent/CN104704128A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201380038875.4A 2012-05-22 2013-05-22 预测乳腺癌结果的nano46基因和方法 Pending CN104704128A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911216650.9A CN111500718A (zh) 2012-05-22 2013-05-22 预测乳腺癌结果的nano46基因和方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261650209P 2012-05-22 2012-05-22
US61/650209 2012-05-22
US201361753673P 2013-01-17 2013-01-17
US61/753673 2013-01-17
PCT/US2013/042157 WO2013177245A2 (en) 2012-05-22 2013-05-22 Nano46 genes and methods to predict breast cancer outcome

Related Child Applications (1)

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CN201911216650.9A Division CN111500718A (zh) 2012-05-22 2013-05-22 预测乳腺癌结果的nano46基因和方法

Publications (1)

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CN104704128A true CN104704128A (zh) 2015-06-10

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CN201380038875.4A Pending CN104704128A (zh) 2012-05-22 2013-05-22 预测乳腺癌结果的nano46基因和方法

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US (3) US20130337444A1 (enExample)
EP (1) EP2852689B1 (enExample)
JP (1) JP6325530B2 (enExample)
CN (2) CN111500718A (enExample)
AU (1) AU2013266419B2 (enExample)
BR (1) BR112014029300A2 (enExample)
CA (1) CA2874492C (enExample)
ES (1) ES2763931T3 (enExample)
IL (1) IL235795B (enExample)
IN (1) IN2014MN02418A (enExample)
MX (1) MX369628B (enExample)
WO (1) WO2013177245A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107850599A (zh) * 2015-07-23 2018-03-27 新加坡国立大学 Wbp2与her2作为共预后因子对患者分层以进行治疗
CN110070915A (zh) * 2017-11-10 2019-07-30 首尔大学医院 下一代利用碱基序列分析的基于机器学习的乳腺癌预后预测方法及预测系统
CN113302313A (zh) * 2018-11-05 2021-08-24 拜恩科技诊断有限责任公司 乳腺癌的预测方法
CN117965734A (zh) * 2024-02-02 2024-05-03 奥明星程(杭州)生物科技有限公司 一种用于检测硬纤维瘤的基因标志物、试剂盒、检测方法及应用

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2297359E (pt) 2008-05-30 2014-03-19 Univ North Carolina Perfis de expressão de genes para prognosticar resultados relativos ao cancro da mama
US9066963B2 (en) 2011-03-15 2015-06-30 The University Of North Carolina At Chapel Hill Methods of treating breast cancer with anthracycline therapy
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
AU2012345789B2 (en) 2011-11-30 2018-02-15 British Columbia Cancer Agency Branch Methods of treating breast cancer with taxane therapy
EP4592400A3 (en) 2012-10-17 2025-10-29 10x Genomics Sweden AB Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
AU2014265623A1 (en) * 2013-05-13 2015-11-26 Nanostring Technologies, Inc. Methods to predict risk of recurrence in node-positive early breast cancer
EP4219745B1 (en) 2013-06-25 2025-09-03 Prognosys Biosciences, Inc. Spatially encoded biological assays using a microfluidic device
WO2015035377A1 (en) * 2013-09-09 2015-03-12 British Columbia Cancer Agency Branch Methods and kits for predicting outcome and methods and kits for treating breast cancer with radiation therapy
US20160194701A1 (en) 2014-11-21 2016-07-07 Nanostring Technologies, Inc. Enzyme- and amplification-free sequencing
AU2015353747B2 (en) * 2014-11-24 2021-02-25 Bruker Spatial Biology, Inc. Methods and apparatuses for gene purification and imaging
AU2015359479A1 (en) * 2014-12-09 2017-06-15 King's College London Breast cancer treatment with taxane therapy
DK3901281T4 (da) 2015-04-10 2025-10-20 Illumina Inc Rumligt adskilt, multipleks nukleinsyreanalyse af biologiske prøver
WO2017201073A1 (en) 2016-05-16 2017-11-23 Nanostring Technologies, Inc. Methods for detecting target nucleic acids in a sample
EP4050112A1 (en) 2016-06-21 2022-08-31 10X Genomics, Inc. Nucleic acid sequencing
WO2018074865A2 (ko) * 2016-10-21 2018-04-26 서울대학교병원 유방암 예후 예측용 조성물 및 방법
US10415080B2 (en) 2016-11-21 2019-09-17 Nanostring Technologies, Inc. Chemical compositions and methods of using same
KR101950717B1 (ko) * 2016-11-23 2019-02-21 주식회사 젠큐릭스 유방암 환자의 화학치료 유용성 예측 방법
WO2018144782A1 (en) * 2017-02-01 2018-08-09 The Translational Genomics Research Institute Methods of detecting somatic and germline variants in impure tumors
ES3029737T3 (en) 2017-10-06 2025-06-25 10X Genomics Inc Rna templated ligation
KR102893736B1 (ko) 2018-05-14 2025-11-28 브루커 스페이셜 바이올로지, 인크. 화학 조성물 및 이의 사용 방법
WO2020240025A1 (en) 2019-05-31 2020-12-03 Cartana Ab Method of detecting target nucleic acid molecules
JP7352937B2 (ja) * 2019-07-19 2023-09-29 公立大学法人福島県立医科大学 乳癌のサブタイプを鑑別又は分類するための鑑別マーカー遺伝子セット、方法およびキット
GB201919032D0 (en) 2019-12-20 2020-02-05 Cartana Ab Method of detecting an analyte
WO2021168287A1 (en) 2020-02-21 2021-08-26 10X Genomics, Inc. Methods and compositions for integrated in situ spatial assay
US12209273B2 (en) 2020-06-12 2025-01-28 10X Genomics, Inc. Nucleic acid assays using click chemistry bioconjugation
EP3945136A1 (en) * 2020-07-28 2022-02-02 Hospital Clínic de Barcelona In vitro method for the prognosis of patients suffering from her2-positive breast cancer
US12297499B2 (en) 2020-08-17 2025-05-13 10X Genomics, Inc. Multicomponent nucleic acid probes for sample analysis
US12060603B2 (en) 2021-01-19 2024-08-13 10X Genomics, Inc. Methods for internally controlled in situ assays using padlock probes
US20250340942A1 (en) * 2021-12-20 2025-11-06 Reveal Genomics S.L Development and validation of an in vitro method for the prognosis of patients suffering from her2-positive breast cancer

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101057144A (zh) * 2004-09-22 2007-10-17 三路影像公司 用于评价乳腺癌预后的方法和组合物
US20100015607A1 (en) * 2005-12-23 2010-01-21 Nanostring Technologies, Inc. Nanoreporters and methods of manufacturing and use thereof
US20110145176A1 (en) * 2008-05-30 2011-06-16 Perou Charles M Gene expression profiles to predict breast cancer outcomes

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
ES2097925T3 (es) 1991-09-18 1997-04-16 Affymax Tech Nv Metodo para sintetizar diversas colecciones de oligomeros.
WO1993009668A1 (en) 1991-11-22 1993-05-27 Affymax Technology N.V. Combinatorial strategies for polymer synthesis
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
EP0880598A4 (en) 1996-01-23 2005-02-23 Affymetrix Inc RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
WO1999023254A1 (en) 1997-10-31 1999-05-14 Affymetrix, Inc. Expression profiles in adult and fetal organs
US6020135A (en) 1998-03-27 2000-02-01 Affymetrix, Inc. P53-regulated genes
US6750015B2 (en) * 2000-06-28 2004-06-15 Kathryn B. Horwitz Progesterone receptor-regulated gene expression and methods related thereto
US20020168639A1 (en) * 2000-09-22 2002-11-14 Muraca Patrick J. Profile array substrates
CA2530738C (en) * 2003-06-24 2020-01-21 Genomic Health, Inc. Prediction of likelihood of cancer recurrence
KR20060120063A (ko) * 2003-09-29 2006-11-24 패스워크 인포메틱스 아이엔씨 생물학적 특징의 탐지 시스템 및 생물학적 특징 탐지 방법
CA2574447A1 (en) 2004-07-15 2006-01-26 University Of Utah Research Foundation Housekeeping genes and methods for identifying the same
EP1954708A4 (en) 2005-11-23 2009-05-13 Univ Utah Res Found Methods and compositions involving intrinsic genes
EP1963500B1 (en) 2005-12-23 2013-02-13 Nanostring Technologies, Inc. Compositions comprising oriented, immobilized macromolecules and methods for their preparation
EP2155899A2 (en) 2007-04-10 2010-02-24 Nanostring Technologies, Inc. Methods and computer systems for identifying target-specific sequences for use in nanoreporters
WO2008150512A2 (en) * 2007-06-04 2008-12-11 University Of Louisville Research Foundation, Inc. Methods for identifying an increased likelihood of recurrence of breast cancer
WO2009108215A1 (en) * 2007-09-06 2009-09-03 Aviaradx, Inc. Tumor grading and cancer prognosis
EP2331704B1 (en) 2008-08-14 2016-11-30 Nanostring Technologies, Inc Stable nanoreporters
HUE030164T2 (en) * 2010-03-31 2017-05-29 Sividon Diagnostics Gmbh A method of predicting breast cancer recurrence during endocrine treatment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101057144A (zh) * 2004-09-22 2007-10-17 三路影像公司 用于评价乳腺癌预后的方法和组合物
US20100015607A1 (en) * 2005-12-23 2010-01-21 Nanostring Technologies, Inc. Nanoreporters and methods of manufacturing and use thereof
US20110145176A1 (en) * 2008-05-30 2011-06-16 Perou Charles M Gene expression profiles to predict breast cancer outcomes

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107850599A (zh) * 2015-07-23 2018-03-27 新加坡国立大学 Wbp2与her2作为共预后因子对患者分层以进行治疗
CN110070915A (zh) * 2017-11-10 2019-07-30 首尔大学医院 下一代利用碱基序列分析的基于机器学习的乳腺癌预后预测方法及预测系统
CN110070915B (zh) * 2017-11-10 2023-08-04 株式会社递希真 下一代利用碱基序列分析的基于机器学习的乳腺癌预后预测方法及预测系统
CN113302313A (zh) * 2018-11-05 2021-08-24 拜恩科技诊断有限责任公司 乳腺癌的预测方法
CN117965734A (zh) * 2024-02-02 2024-05-03 奥明星程(杭州)生物科技有限公司 一种用于检测硬纤维瘤的基因标志物、试剂盒、检测方法及应用

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US20200332368A1 (en) 2020-10-22
ES2763931T3 (es) 2020-06-01
IL235795A0 (en) 2015-01-29
EP2852689A2 (en) 2015-04-01
MX2014014275A (es) 2015-07-06
MX369628B (es) 2019-11-14
US20230272476A1 (en) 2023-08-31
CA2874492C (en) 2021-10-19
CN111500718A (zh) 2020-08-07
BR112014029300A2 (pt) 2017-07-25
AU2013266419B2 (en) 2018-09-27
AU2013266419A1 (en) 2014-12-11
IN2014MN02418A (enExample) 2015-08-14
JP6325530B2 (ja) 2018-05-16
CA2874492A1 (en) 2013-11-28
EP2852689B1 (en) 2019-12-11
WO2013177245A3 (en) 2015-01-29
EP2852689A4 (en) 2016-05-11
WO2013177245A2 (en) 2013-11-28
US20130337444A1 (en) 2013-12-19
JP2015518724A (ja) 2015-07-06
IL235795B (en) 2020-02-27

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