JP2015517305A5 - - Google Patents

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JP2015517305A5
JP2015517305A5 JP2015510818A JP2015510818A JP2015517305A5 JP 2015517305 A5 JP2015517305 A5 JP 2015517305A5 JP 2015510818 A JP2015510818 A JP 2015510818A JP 2015510818 A JP2015510818 A JP 2015510818A JP 2015517305 A5 JP2015517305 A5 JP 2015517305A5
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Japan
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seq
fxia
amino acid
acid sequence
antibody
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JP2015510818A
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JP2015517305A (ja
JP6348900B2 (ja
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Priority claimed from PCT/EP2013/059618 external-priority patent/WO2013167669A1/en
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JP2015510818A 2012-05-10 2013-05-08 凝固因子ｘｉおよび／またはその活性化形態である因子ｘｉａに結合しうる抗体ならびにその用途 Active JP6348900B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP12167438.6 2012-05-10
EP12167438 2012-05-10
EP12181697.9 2012-08-24
EP12181697 2012-08-24
EP13150361.7 2013-01-07
EP13150361 2013-01-07
US201361817675P 2013-04-30 2013-04-30
US61/817,675 2013-04-30
PCT/EP2013/059618 WO2013167669A1 (en) 2012-05-10 2013-05-08 Antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and uses thereof

Related Child Applications (1)

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JP2018106275A Division JP2018148920A (ja) 2012-05-10 2018-06-01 凝固因子ｘｉおよび／またはその活性化形態である因子ｘｉａに結合しうる抗体ならびにその用途

Publications (3)

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JP2015517305A JP2015517305A (ja) 2015-06-22
JP2015517305A5 true JP2015517305A5 (https=) 2016-06-23
JP6348900B2 JP6348900B2 (ja) 2018-06-27

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JP2015510818A Active JP6348900B2 (ja) 2012-05-10 2013-05-08 凝固因子ｘｉおよび／またはその活性化形態である因子ｘｉａに結合しうる抗体ならびにその用途
JP2018106275A Pending JP2018148920A (ja) 2012-05-10 2018-06-01 凝固因子ｘｉおよび／またはその活性化形態である因子ｘｉａに結合しうる抗体ならびにその用途

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Country Status (24)

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US (4) US9783614B2 (https=)
EP (2) EP2847228B1 (https=)
JP (2) JP6348900B2 (https=)
KR (1) KR102060376B1 (https=)
CN (1) CN104684932B (https=)
AR (1) AR091024A1 (https=)
AU (2) AU2013258043B2 (https=)
BR (1) BR112014027952B1 (https=)
CA (1) CA2872926C (https=)
DK (1) DK2847228T3 (https=)
ES (1) ES2698950T3 (https=)
HR (1) HRP20181680T1 (https=)
HU (1) HUE040580T2 (https=)
IL (1) IL235238B (https=)
LT (1) LT2847228T (https=)
MX (1) MX362454B (https=)
NZ (1) NZ701121A (https=)
PL (1) PL2847228T3 (https=)
RS (1) RS57889B1 (https=)
SG (2) SG10201609322QA (https=)
SI (1) SI2847228T1 (https=)
TW (2) TWI644925B (https=)
WO (1) WO2013167669A1 (https=)
ZA (1) ZA201407784B (https=)

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WO2017015619A1 (en) 2015-07-23 2017-01-26 The Regents Of The University Of California Antibodies to coagulation factor xia and uses thereof
TWI736575B (zh) * 2016-01-22 2021-08-21 美商默沙東藥廠 抗凝固因子ｘｉ抗體
CN109153726A (zh) * 2016-03-23 2019-01-04 普希克斯私人有限公司 抗因子xi的活性位点的单克隆抗体及其用途
TW201802121A (zh) 2016-05-25 2018-01-16 諾華公司 抗因子XI/XIa抗體之逆轉結合劑及其用途
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CN110325211A (zh) * 2016-12-23 2019-10-11 诺华股份有限公司 采用抗因子XI/XIa抗体治疗的方法
IL267538B2 (en) 2016-12-23 2024-05-01 Novartis Ag Antibodies against factor XI and methods for use in preventing, treating, managing or reducing the risk of thromboembolic disorder or stroke in a patient
CA3050172A1 (en) * 2017-01-19 2018-07-26 Bayer Pharma Aktiengesellschaft Novel stable formulation for fxia antibodies
CN108409863B (zh) * 2017-02-10 2023-09-26 上海仁会生物制药股份有限公司 抗凝血因子xi抗体
US11958911B2 (en) * 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody
KR20200087236A (ko) * 2017-11-22 2020-07-20 노파르티스 아게 항-인자 XI/XIa 항체에 대한 반전 결합제 및 이의 용도
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JP6761142B1 (ja) * 2018-08-01 2020-09-23 ノヴォ ノルディスク アー／エス 改良された血液凝固促進抗体
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EP3852820B1 (en) 2018-09-17 2024-11-20 Board of Regents, The University of Texas System Compositions and methods for treating bone injury
EP3873944A1 (en) 2018-10-31 2021-09-08 Bayer Aktiengesellschaft Reversal agents for neutralizing the therapeutic activity of anti-fxia antibodies
CA3125303A1 (en) * 2019-01-21 2020-07-30 Aronora Inc. Novel humanized antibodies against factor xi having anti-thrombotic and anti-inflammatory effects and uses thereof
JP7650807B2 (ja) 2019-04-16 2025-03-25 シチュアン ケルン－バイオテック バイオファーマシューティカル カンパニー リミテッド 抗ＦＸＩ／ＦＸＩａ抗体及びその使用
CN110423278B (zh) 2019-08-08 2020-07-17 上海博槿生物科技有限公司 一种抗凝血因子XI活化形式因子XIa的抗体及其制备方法和应用
JP2023106635A (ja) 2020-04-17 2023-08-02 中外製薬株式会社 二重特異性抗原結合分子ならびに、それに関連する組成物、組成物の製造のための使用、キット、および方法
EP4177274A4 (en) * 2020-07-02 2024-04-03 Beijing Tuo Jie Biopharmaceutical Co. Ltd. Anti-fxi/fxia antibody, antigen-binding fragment thereof, and pharmaceutical use thereof
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