JP2015513398A5 - - Google Patents
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- JP2015513398A5 JP2015513398A5 JP2014558247A JP2014558247A JP2015513398A5 JP 2015513398 A5 JP2015513398 A5 JP 2015513398A5 JP 2014558247 A JP2014558247 A JP 2014558247A JP 2014558247 A JP2014558247 A JP 2014558247A JP 2015513398 A5 JP2015513398 A5 JP 2015513398A5
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- Prior art keywords
- oligonucleotide
- seq
- gene
- oligonucleotide according
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000002773 nucleotide Substances 0.000 claims 9
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- 206010028980 Neoplasm Diseases 0.000 claims 6
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- 108090000623 proteins and genes Proteins 0.000 claims 6
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| JP2015518712A (ja) | 2012-05-16 | 2015-07-06 | ラナ セラピューティクス インコーポレイテッド | Mecp2発現を調節するための組成物及び方法 |
| JP2015518713A (ja) | 2012-05-16 | 2015-07-06 | ラナ セラピューティクス インコーポレイテッド | Utrn発現を調節するための組成物及び方法 |
| US10837014B2 (en) | 2012-05-16 | 2020-11-17 | Translate Bio Ma, Inc. | Compositions and methods for modulating SMN gene family expression |
| CN104583401A (zh) | 2012-05-16 | 2015-04-29 | Rana医疗有限公司 | 用于调节atp2a2表达的组合物和方法 |
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| JP2004524371A (ja) * | 2001-04-13 | 2004-08-12 | ザ・ポピュレイション・カウンシル,インコーポレイテッド | 核レセプターを介するペプチド核酸の細胞核内導入 |
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| MX2007004968A (es) * | 2004-10-25 | 2007-06-15 | Novartis Ag | Polinucleotidos y polipeptidos torc, y metodos de uso. |
| JP5623016B2 (ja) * | 2005-12-01 | 2014-11-12 | プロネイ・セラピューティクス・インコーポレイテッドPronaitherapeutics, Inc. | 癌治療法およびそれに用いる医薬組成物 |
| US7625874B2 (en) * | 2006-04-11 | 2009-12-01 | The Regents Of The University Of California | Compositions and methods for treating diseases associated with T-box and N-Myc |
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| US20090047295A1 (en) * | 2007-07-12 | 2009-02-19 | Berry David A | Methods and Compositions for Reducing Stemness in Oncogenesis |
| US20110105422A1 (en) * | 2008-02-05 | 2011-05-05 | Gary Acton | Use of g-rich oligonucleotides for treating neoplastic diseases |
| EP2370582B1 (en) * | 2008-12-04 | 2017-05-10 | CuRNA, Inc. | Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene |
| CN102058535B (zh) * | 2010-12-21 | 2013-05-01 | 中国人民解放军总医院 | 叶酸受体靶向的新型脂质体 |
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