JP2022550979A5 - - Google Patents
Info
- Publication number
- JP2022550979A5 JP2022550979A5 JP2022520896A JP2022520896A JP2022550979A5 JP 2022550979 A5 JP2022550979 A5 JP 2022550979A5 JP 2022520896 A JP2022520896 A JP 2022520896A JP 2022520896 A JP2022520896 A JP 2022520896A JP 2022550979 A5 JP2022550979 A5 JP 2022550979A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleotide
- double
- stranded rna
- molecule according
- rna molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025174393A JP2026002913A (ja) | 2019-10-11 | 2025-10-16 | 修飾オリゴヌクレオチド |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962914010P | 2019-10-11 | 2019-10-11 | |
| US62/914,010 | 2019-10-11 | ||
| PCT/US2020/055301 WO2021072395A1 (en) | 2019-10-11 | 2020-10-13 | Modified oligonucleotides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025174393A Division JP2026002913A (ja) | 2019-10-11 | 2025-10-16 | 修飾オリゴヌクレオチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022550979A JP2022550979A (ja) | 2022-12-06 |
| JP2022550979A5 true JP2022550979A5 (enExample) | 2023-10-23 |
| JP7761558B2 JP7761558B2 (ja) | 2025-10-28 |
Family
ID=75436777
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022520896A Active JP7761558B2 (ja) | 2019-10-11 | 2020-10-13 | 修飾オリゴヌクレオチド |
| JP2025174393A Pending JP2026002913A (ja) | 2019-10-11 | 2025-10-16 | 修飾オリゴヌクレオチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025174393A Pending JP2026002913A (ja) | 2019-10-11 | 2025-10-16 | 修飾オリゴヌクレオチド |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US12497613B2 (enExample) |
| EP (1) | EP4041248A4 (enExample) |
| JP (2) | JP7761558B2 (enExample) |
| AU (1) | AU2020364248A1 (enExample) |
| CA (1) | CA3157486A1 (enExample) |
| WO (1) | WO2021072395A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018098328A1 (en) | 2016-11-23 | 2018-05-31 | Alnylam Pharmaceuticals, Inc. | Modified rna agents with reduced off-target effect |
| US11597744B2 (en) | 2017-06-30 | 2023-03-07 | Sirius Therapeutics, Inc. | Chiral phosphoramidite auxiliaries and methods of their use |
| WO2019217397A2 (en) | 2018-05-07 | 2019-11-14 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for improving strand biased |
| US20230407302A1 (en) * | 2022-02-04 | 2023-12-21 | New York University | Novel efficacious microrna-30c analogs reduce apolipoprotein b secretion in human liver cells |
| EP4532724A4 (en) * | 2022-06-02 | 2026-06-24 | Ionis Pharmaceuticals Inc | LINKED MODIFIED OLIGOMER COMPOUNDS AND THEIR USES |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10133858A1 (de) | 2001-07-12 | 2003-02-06 | Aventis Pharma Gmbh | Synthetische doppelsträngige Oligonucleotide zur gezielten Hemmung der Genexpression |
| WO2006047842A2 (en) | 2004-11-08 | 2006-05-11 | K.U. Leuven Research And Development | Modified nucleosides for rna interference |
| WO2008025160A1 (en) * | 2006-08-31 | 2008-03-06 | Mcgill University | Oxepane nucleosides and oligonucleotides, uses thereof and methods of making the same |
| JP2009215241A (ja) * | 2008-03-11 | 2009-09-24 | Gifu Univ | ピラノース環を有するヌクレオシド類似体、核酸類似体及び核酸 |
| US10023861B2 (en) * | 2011-08-29 | 2018-07-17 | Ionis Pharmaceuticals, Inc. | Oligomer-conjugate complexes and their use |
-
2020
- 2020-10-13 EP EP20873934.2A patent/EP4041248A4/en active Pending
- 2020-10-13 JP JP2022520896A patent/JP7761558B2/ja active Active
- 2020-10-13 US US17/767,190 patent/US12497613B2/en active Active
- 2020-10-13 AU AU2020364248A patent/AU2020364248A1/en active Pending
- 2020-10-13 WO PCT/US2020/055301 patent/WO2021072395A1/en not_active Ceased
- 2020-10-13 CA CA3157486A patent/CA3157486A1/en active Pending
-
2025
- 2025-10-16 JP JP2025174393A patent/JP2026002913A/ja active Pending
- 2025-11-04 US US19/379,170 patent/US20260055401A1/en active Pending
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