JP2015502365A5 - - Google Patents

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JP2015502365A5
JP2015502365A5 JP2014547389A JP2014547389A JP2015502365A5 JP 2015502365 A5 JP2015502365 A5 JP 2015502365A5 JP 2014547389 A JP2014547389 A JP 2014547389A JP 2014547389 A JP2014547389 A JP 2014547389A JP 2015502365 A5 JP2015502365 A5 JP 2015502365A5
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diseases
disorders
oligonucleotide
composition
disease
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JP2014547389A
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JP2015502365A (ja
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Priority claimed from PCT/US2012/069294 external-priority patent/WO2013090457A2/en
Publication of JP2015502365A publication Critical patent/JP2015502365A/ja
Publication of JP2015502365A5 publication Critical patent/JP2015502365A5/ja
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JP2014547389A 2011-12-12 2012-12-12 オリゴヌクレオチドのイン−ビボ送達 Pending JP2015502365A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161630446P 2011-12-12 2011-12-12
US61/630,446 2011-12-12
PCT/US2012/069294 WO2013090457A2 (en) 2011-12-12 2012-12-12 In vivo delivery of oligonucleotides

Related Child Applications (1)

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JP2019017110A Division JP2019073548A (ja) 2011-12-12 2019-02-01 オリゴヌクレオチドのイン−ビボ送達

Publications (2)

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JP2015502365A JP2015502365A (ja) 2015-01-22
JP2015502365A5 true JP2015502365A5 (enExample) 2017-06-15

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JP2014547389A Pending JP2015502365A (ja) 2011-12-12 2012-12-12 オリゴヌクレオチドのイン−ビボ送達
JP2019017110A Pending JP2019073548A (ja) 2011-12-12 2019-02-01 オリゴヌクレオチドのイン−ビボ送達

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US (4) US10557136B2 (enExample)
EP (1) EP2790736B1 (enExample)
JP (2) JP2015502365A (enExample)
CA (1) CA2895077A1 (enExample)
DK (1) DK2790736T3 (enExample)
WO (1) WO2013090457A2 (enExample)

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CA2895077A1 (en) 2011-12-12 2013-06-20 Beverly Packard In vivo delivery of oligonucleotides
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CN110257379B (zh) * 2012-07-03 2023-08-11 马林生物科技有限公司 用于治疗肌肉萎缩症患者的寡核苷酸
JP6268157B2 (ja) 2012-07-13 2018-01-24 株式会社Ｗａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｊａｐａｎ 不斉補助基
KR102712879B1 (ko) 2012-07-13 2024-10-04 웨이브 라이프 사이언시스 리미티드 키랄 제어
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JPWO2015108048A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
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WO2015161255A1 (en) * 2014-04-18 2015-10-22 Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno Methods for enhancing or decreasing the levels of mir124 and mir29 in subjects with muscular dystrophy
PL3143123T3 (pl) * 2014-05-16 2020-07-13 The Trustees Of The University Of Pennsylvania Indukcja regeneracji serca za pomocą mikroRNA
JP2018503646A (ja) 2015-01-20 2018-02-08 ミラゲン セラピューティクス， インコーポレイテッド ｍｉＲ−９２阻害剤およびその使用
SG10201912902TA (en) 2015-10-09 2020-02-27 Wave Life Sciences Ltd Oligonucleotide compositions and methods thereof
WO2018065390A1 (en) * 2016-10-04 2018-04-12 Vib Vzw Means and methods to treat inflammatory diseases
JP2021529173A (ja) 2018-06-20 2021-10-28 イエール ユニバーシティ Ｒｉｇ−ｉアゴニストおよびそれを使用した処置
WO2020181130A2 (en) * 2019-03-05 2020-09-10 MiRagen Therapeutics, Inc. Polynucleotide conjugates and uses thereof
MX2021012098A (es) * 2019-04-03 2021-11-03 Bristol Myers Squibb Co Oligonucleotidos antisentido del transcrito tipo 2 de angiopoyetina (angptl2) y sus usos.
EP4005602A4 (en) * 2019-07-30 2024-06-12 Shionogi & Co., Ltd NUCLEIC ACID AGENT TARGETED AGAINST MURF1
US20230201361A1 (en) * 2020-01-11 2023-06-29 Oncolmmunin, Inc. Targeted and localized in vivo delivery of oligonucleotides
US11649457B2 (en) 2020-12-09 2023-05-16 Yale University Methods for treating SARS-CoV-2 infection
US11786545B2 (en) 2020-12-09 2023-10-17 Yale University Compositions and methods for treating SARS-CoV-2 infection
WO2022232223A1 (en) * 2021-04-28 2022-11-03 The Johns Hopkins University Treating cancer
CN113975397B (zh) * 2021-10-26 2023-08-22 中南大学湘雅三医院 一种基因/小分子化合物纳米递药系统及其制备方法与应用

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