AU2013223694B2 - Oligonucleotides for modulating gene expression and uses thereof - Google Patents

Oligonucleotides for modulating gene expression and uses thereof Download PDF

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AU2013223694B2
AU2013223694B2 AU2013223694A AU2013223694A AU2013223694B2 AU 2013223694 B2 AU2013223694 B2 AU 2013223694B2 AU 2013223694 A AU2013223694 A AU 2013223694A AU 2013223694 A AU2013223694 A AU 2013223694A AU 2013223694 B2 AU2013223694 B2 AU 2013223694B2
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seq
oligonucleotide
oligonucleotides
gene
leukaemia
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AU2013223694A1 (en
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Luca MONTEMURRO
Roberto Tonelli
Andrea TORTORI
Leonardo VENTURELLI
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Biogenera SpA
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
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AU2013223694A 2012-02-24 2013-02-21 Oligonucleotides for modulating gene expression and uses thereof Active AU2013223694B2 (en)

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ITMI2012A000275 2012-02-24
IT000275A ITMI20120275A1 (it) 2012-02-24 2012-02-24 Oligonucleotidi per la modulazione dell'espressione genica e loro usi
PCT/IB2013/051410 WO2013124807A2 (en) 2012-02-24 2013-02-21 Oligonucleotides for modulating gene expression and uses thereof

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