JP2015513357A5 - - Google Patents

Info

Publication number

JP2015513357A5

JP2015513357A5 JP2015500983A JP2015500983A JP2015513357A5 JP 2015513357 A5 JP2015513357 A5 JP 2015513357A5 JP 2015500983 A JP2015500983 A JP 2015500983A JP 2015500983 A JP2015500983 A JP 2015500983A JP 2015513357 A5 JP2015513357 A5 JP 2015513357A5

Authority

JP

Japan

Prior art keywords

skin

melibiose

composition

cosmetic

cosmetic method

Prior art date

2013-03-19

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 238000000034 method Methods 0.000 claims description 61
• 239000000203 mixture Substances 0.000 claims description 49
• 239000002537 cosmetic Substances 0.000 claims description 34
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• 208000000069 hyperpigmentation Diseases 0.000 claims description 16
• 230000003810 hyperpigmentation Effects 0.000 claims description 16
• 208000003351 Melanosis Diseases 0.000 claims description 14
• 230000000699 topical effect Effects 0.000 claims description 12
• 230000002087 whitening effect Effects 0.000 claims description 12
• 208000012641 Pigmentation disease Diseases 0.000 claims description 10
• 150000003839 salts Chemical class 0.000 claims description 9
• 201000004624 Dermatitis Diseases 0.000 claims description 8
• 206010047642 Vitiligo Diseases 0.000 claims description 8
• 208000031019 skin pigmentation disease Diseases 0.000 claims description 8
• 208000007256 Nevus Diseases 0.000 claims description 7
• 229920001542 oligosaccharide Polymers 0.000 claims description 7
• 150000002482 oligosaccharides Chemical class 0.000 claims description 7
• 239000000546 pharmaceutical excipient Substances 0.000 claims description 7
• 206010061218 Inflammation Diseases 0.000 claims description 6
• 238000004903 NDO Methods 0.000 claims description 6
• 206010064127 Solar lentigo Diseases 0.000 claims description 6
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• 239000000443 aerosol Substances 0.000 claims description 5
• 239000006071 cream Substances 0.000 claims description 5
• 239000000839 emulsion Substances 0.000 claims description 5
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• 239000006260 foam Substances 0.000 claims description 5
• 239000000499 gel Substances 0.000 claims description 5
• 239000000017 hydrogel Substances 0.000 claims description 5
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• 229940029339 inulin Drugs 0.000 description 3
• JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 description 3
• 229960000511 lactulose Drugs 0.000 description 3
• PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 description 3
• MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 3
• 210000000813 small intestine Anatomy 0.000 description 3
• UQZIYBXSHAGNOE-XNSRJBNMSA-N stachyose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)O2)O)O1 UQZIYBXSHAGNOE-XNSRJBNMSA-N 0.000 description 3
• 238000003756 stirring Methods 0.000 description 3
• RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 2
• PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
• 102000004890 Interleukin-8 Human genes 0.000 description 2
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• 230000000770 proinflammatory effect Effects 0.000 description 2
• 208000002874 Acne Vulgaris Diseases 0.000 description 1
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• 102000004127 Cytokines Human genes 0.000 description 1
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• 206010012438 Dermatitis atopic Diseases 0.000 description 1
• 206010012442 Dermatitis contact Diseases 0.000 description 1
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
• 201000004681 Psoriasis Diseases 0.000 description 1
• 206010000496 acne Diseases 0.000 description 1
• 239000013543 active substance Substances 0.000 description 1
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• 230000003796 beauty Effects 0.000 description 1
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• 239000011928 denatured alcohol Substances 0.000 description 1
• 239000003085 diluting agent Substances 0.000 description 1
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• FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 description 1
• 229940107187 fructooligosaccharide Drugs 0.000 description 1
• 235000011187 glycerol Nutrition 0.000 description 1
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• XKTZWUACRZHVAN-VADRZIEHSA-N interleukin-8 Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](NC(C)=O)CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1[C@H](CCC1)C(=O)N1[C@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC(O)=CC=1)C(=O)N[C@H](CO)C(=O)N1[C@H](CCC1)C(N)=O)C1=CC=CC=C1 XKTZWUACRZHVAN-VADRZIEHSA-N 0.000 description 1
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