JP2015508291A5 - - Google Patents
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- Publication number
- JP2015508291A5 JP2015508291A5 JP2014553735A JP2014553735A JP2015508291A5 JP 2015508291 A5 JP2015508291 A5 JP 2015508291A5 JP 2014553735 A JP2014553735 A JP 2014553735A JP 2014553735 A JP2014553735 A JP 2014553735A JP 2015508291 A5 JP2015508291 A5 JP 2015508291A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- enzyme
- acid sequence
- galactosyl
- leaving group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000002519 galactosyl group Chemical group C1([C@H](O)[C@@H](O)[C@@H](O)[C@H](O1)CO)* 0.000 claims 26
- 238000000034 method Methods 0.000 claims 24
- 125000003275 alpha amino acid group Chemical group 0.000 claims 19
- 102000004190 Enzymes Human genes 0.000 claims 18
- 108090000790 Enzymes Proteins 0.000 claims 18
- 229940088598 enzyme Drugs 0.000 claims 18
- 239000000203 mixture Substances 0.000 claims 11
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 7
- 235000021255 galacto-oligosaccharides Nutrition 0.000 claims 4
- 150000003271 galactooligosaccharides Chemical class 0.000 claims 4
- 239000012084 conversion product Substances 0.000 claims 2
- 238000011534 incubation Methods 0.000 claims 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 2
- 244000005700 microbiome Species 0.000 claims 2
- 239000002516 radical scavenger Substances 0.000 claims 2
- 102100026189 Beta-galactosidase Human genes 0.000 claims 1
- 102100035882 Catalase Human genes 0.000 claims 1
- 108010053835 Catalase Proteins 0.000 claims 1
- 108010015776 Glucose oxidase Proteins 0.000 claims 1
- 239000004366 Glucose oxidase Substances 0.000 claims 1
- 238000005349 anion exchange Methods 0.000 claims 1
- 108010005774 beta-Galactosidase Proteins 0.000 claims 1
- 239000013626 chemical specie Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000003795 desorption Methods 0.000 claims 1
- 229940116332 glucose oxidase Drugs 0.000 claims 1
- 235000019420 glucose oxidase Nutrition 0.000 claims 1
- 125000003147 glycosyl group Chemical group 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 claims 1
- 229960003451 lactitol Drugs 0.000 claims 1
- 235000010448 lactitol Nutrition 0.000 claims 1
- 239000000832 lactitol Substances 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 150000005846 sugar alcohols Chemical class 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261590503P | 2012-01-25 | 2012-01-25 | |
| EP12152502.6A EP2620506A1 (en) | 2012-01-25 | 2012-01-25 | Method of producing a galacto-oligosaccharide-containing composition |
| US61/590,503 | 2012-01-25 | ||
| EP12152502.6 | 2012-01-25 | ||
| PCT/EP2013/051477 WO2013110778A1 (en) | 2012-01-25 | 2013-01-25 | Method of producing a composition containing galacto-oligosaccharides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015508291A JP2015508291A (ja) | 2015-03-19 |
| JP2015508291A5 true JP2015508291A5 (enExample) | 2016-04-07 |
| JP6183921B2 JP6183921B2 (ja) | 2017-08-23 |
Family
ID=45524414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014553735A Expired - Fee Related JP6183921B2 (ja) | 2012-01-25 | 2013-01-25 | ガラクトオリゴ糖含有組成物の製造方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20150037847A1 (enExample) |
| EP (2) | EP2620506A1 (enExample) |
| JP (1) | JP6183921B2 (enExample) |
| KR (1) | KR20140126336A (enExample) |
| CN (1) | CN104136618B (enExample) |
| AR (1) | AR089822A1 (enExample) |
| AU (1) | AU2013213524B2 (enExample) |
| BR (1) | BR112014018032A2 (enExample) |
| CA (1) | CA2861966A1 (enExample) |
| CL (1) | CL2014001960A1 (enExample) |
| DK (1) | DK2807264T3 (enExample) |
| EA (1) | EA028927B1 (enExample) |
| IN (1) | IN2014DN06831A (enExample) |
| MX (1) | MX2014008935A (enExample) |
| NZ (1) | NZ627138A (enExample) |
| SG (2) | SG10201606132RA (enExample) |
| WO (1) | WO2013110778A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3473712A1 (en) | 2012-06-08 | 2019-04-24 | DuPont Nutrition Biosciences ApS | Polypeptides having transgalactosylating activity |
| WO2013190529A1 (en) * | 2012-06-22 | 2013-12-27 | Glycom A/S | Glycosylated galactosyl disaccharddes, methods for their production and their use in consumable products |
| US20150182549A1 (en) * | 2012-06-22 | 2015-07-02 | Glycom A/S | Method for enzymatic glycosylation of oligosaccharides from mammalian animal milk |
| TWI793159B (zh) | 2013-10-23 | 2023-02-21 | 美商健臻公司 | 重組醣蛋白及其用途 |
| CA2992497C (en) * | 2016-01-12 | 2020-12-22 | Vitalus Nutrition Inc. | Method for producing galactooligosaccharides from lactose |
| AU2017326654C1 (en) * | 2016-09-19 | 2022-07-21 | Prolacta Bioscience, Inc. | Purified human milk oligosaccharides compositions |
| CN107410502B (zh) * | 2017-04-28 | 2018-08-24 | 黑龙江省北大荒绿色健康食品有限责任公司 | 一种低敏性速溶马铃薯豆奶粉的制备方法 |
| US20210010045A1 (en) * | 2017-07-04 | 2021-01-14 | Kabushiki Kaisha Yakult Honsha | Method for producing galactooligosaccharide |
| CN108384821B (zh) * | 2017-12-18 | 2021-09-14 | 江苏省农业科学院 | 一种促进肠道益生菌增殖的低聚糖的制备方法 |
| CN108588006A (zh) * | 2018-05-10 | 2018-09-28 | 华东理工大学 | 一种用于肝细胞三维培养的生物支架及其制备方法和应用 |
| US12364721B2 (en) | 2019-09-24 | 2025-07-22 | Prolacta Bioscience, Inc. | Compositions and methods for treatment of inflammatory and immune diseases |
| CN112251481B (zh) * | 2020-11-13 | 2022-08-26 | 广东省农业科学院蚕业与农产品加工研究所 | 一种低聚半乳糖的制备方法 |
| EP4101301A1 (de) | 2021-06-08 | 2022-12-14 | DMK Deutsches Milchkontor GmbH | Verfahren zur herstellung von galactooligosacchariden |
| EP4249600A1 (de) | 2022-03-24 | 2023-09-27 | DMK Deutsches Milchkontor GmbH | Galactooligosaccharid-zubereitungen mit gelförmiger konsistenz |
| EP4385332A1 (de) | 2022-12-15 | 2024-06-19 | DMK Deutsches Milchkontor GmbH | Kalorienarme süssspeisen |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5042431B2 (ja) * | 2000-05-26 | 2012-10-03 | アルラ・フーズ・エイ・エム・ビィ・エイ | Ｂｉｆｉｄｏｂａｃｔｅｒｉｕｍから単離された新たな酵素 |
| EP2252699B1 (en) * | 2008-03-12 | 2015-05-27 | Tata Chemicals Limited | Production of galactooligosaccharides by Bullera singularis and Saccharomyces sp. |
| EP2138586A1 (en) * | 2008-06-24 | 2009-12-30 | Cognis IP Management GmbH | Process for the regioselective preparation of disaccharides or oligosaccharides |
| EP2552945B1 (en) | 2010-03-29 | 2018-05-02 | DuPont Nutrition Biosciences ApS | Polypeptides having transgalactosylating activity |
| WO2012010597A1 (en) * | 2010-07-19 | 2012-01-26 | Arla Foods Amba | Galacto-oligosaccharide-containing composition and a method of producing it |
-
2012
- 2012-01-25 EP EP12152502.6A patent/EP2620506A1/en not_active Withdrawn
-
2013
- 2013-01-25 KR KR1020147023525A patent/KR20140126336A/ko not_active Withdrawn
- 2013-01-25 IN IN6831DEN2014 patent/IN2014DN06831A/en unknown
- 2013-01-25 AU AU2013213524A patent/AU2013213524B2/en not_active Ceased
- 2013-01-25 AR ARP130100245A patent/AR089822A1/es unknown
- 2013-01-25 EA EA201491195A patent/EA028927B1/ru not_active IP Right Cessation
- 2013-01-25 US US14/374,708 patent/US20150037847A1/en not_active Abandoned
- 2013-01-25 JP JP2014553735A patent/JP6183921B2/ja not_active Expired - Fee Related
- 2013-01-25 CN CN201380006361.0A patent/CN104136618B/zh not_active Expired - Fee Related
- 2013-01-25 SG SG10201606132RA patent/SG10201606132RA/en unknown
- 2013-01-25 EP EP13703536.6A patent/EP2807264B1/en active Active
- 2013-01-25 BR BR112014018032A patent/BR112014018032A2/pt not_active IP Right Cessation
- 2013-01-25 NZ NZ627138A patent/NZ627138A/en not_active IP Right Cessation
- 2013-01-25 WO PCT/EP2013/051477 patent/WO2013110778A1/en not_active Ceased
- 2013-01-25 DK DK13703536.6T patent/DK2807264T3/en active
- 2013-01-25 MX MX2014008935A patent/MX2014008935A/es unknown
- 2013-01-25 CA CA2861966A patent/CA2861966A1/en not_active Abandoned
- 2013-01-25 SG SG11201404110SA patent/SG11201404110SA/en unknown
-
2014
- 2014-07-24 CL CL2014001960A patent/CL2014001960A1/es unknown
-
2016
- 2016-10-21 US US15/331,743 patent/US20170067086A1/en not_active Abandoned
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