JP2015506961A5 - - Google Patents

Download PDF

Info

Publication number
JP2015506961A5
JP2015506961A5 JP2014555801A JP2014555801A JP2015506961A5 JP 2015506961 A5 JP2015506961 A5 JP 2015506961A5 JP 2014555801 A JP2014555801 A JP 2014555801A JP 2014555801 A JP2014555801 A JP 2014555801A JP 2015506961 A5 JP2015506961 A5 JP 2015506961A5
Authority
JP
Japan
Prior art keywords
renal cell
cell carcinoma
optionally
therapeutic agent
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014555801A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015506961A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/024510 external-priority patent/WO2013116781A1/en
Publication of JP2015506961A publication Critical patent/JP2015506961A/ja
Publication of JP2015506961A5 publication Critical patent/JP2015506961A5/ja
Pending legal-status Critical Current

Links

JP2014555801A 2012-02-02 2013-02-01 Alk1アンタゴニストおよび腎細胞癌の治療におけるその使用 Pending JP2015506961A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261593864P 2012-02-02 2012-02-02
US61/593,864 2012-02-02
US201261597124P 2012-02-09 2012-02-09
US61/597,124 2012-02-09
PCT/US2013/024510 WO2013116781A1 (en) 2012-02-02 2013-02-01 Alk1 antagonists and their uses in treating renal cell carcinoma

Publications (2)

Publication Number Publication Date
JP2015506961A JP2015506961A (ja) 2015-03-05
JP2015506961A5 true JP2015506961A5 (enExample) 2016-03-17

Family

ID=48903082

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014555801A Pending JP2015506961A (ja) 2012-02-02 2013-02-01 Alk1アンタゴニストおよび腎細胞癌の治療におけるその使用

Country Status (11)

Country Link
US (1) US20130202594A1 (enExample)
EP (1) EP2809335A4 (enExample)
JP (1) JP2015506961A (enExample)
KR (1) KR20140123558A (enExample)
CN (1) CN104321070A (enExample)
AU (1) AU2013214779A1 (enExample)
BR (1) BR112014019151A2 (enExample)
CA (1) CA2863188A1 (enExample)
MX (1) MX2014009277A (enExample)
RU (1) RU2633638C2 (enExample)
WO (1) WO2013116781A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10059756B2 (en) 2006-11-02 2018-08-28 Acceleron Pharma Inc. Compositions comprising ALK1-ECD protein
CN111518218A (zh) 2006-11-02 2020-08-11 阿塞勒隆制药公司 Alk1受体和配体拮抗剂及其用途
US8642031B2 (en) 2006-11-02 2014-02-04 Acceleron Pharma, Inc. Antagonists of BMP9, BMP10, ALK1 and other ALK1 ligands, and uses thereof
WO2015147908A1 (en) * 2014-03-28 2015-10-01 Acceleron Pharma, Inc. Use of activin receptor-like kinase 1 (alk-1) antagonists in the treatment of cancer
JP2016036322A (ja) * 2014-08-11 2016-03-22 日本化薬株式会社 血管新生因子と結合するキメラタンパク質
US20180042998A1 (en) * 2015-03-10 2018-02-15 University Of Massachusetts Targeting gdf6 and bmp signaling for anti-melanoma therapy
EA201792561A1 (ru) 2015-06-05 2018-04-30 Новартис Аг Антитела, нацеленные на морфогенетический белок кости 9 (bmp9), и способы их применения
CN106994181A (zh) * 2017-03-10 2017-08-01 上海交通大学医学院附属第九人民医院 Bmp9在制备延缓肝纤维化药物中的应用
CN110662762A (zh) 2017-05-24 2020-01-07 诺华股份有限公司 抗体细胞因子移植蛋白和用于治疗癌症的方法
WO2019173482A1 (en) * 2018-03-06 2019-09-12 Sanford Burnham Prebys Medical Discovery Institute 4-aminoquinoline compounds for the treatment of angiogenesis
EP4688147A1 (en) 2023-04-07 2026-02-11 Diagonal Therapeutics Inc. Bispecific agonistic antibodies to activin a receptor like type 1 (alk1)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8529014D0 (en) 1985-11-25 1986-01-02 Biogen Nv Enhanced secretion of heterologous proteins
WO1987005330A1 (en) 1986-03-07 1987-09-11 Michel Louis Eugene Bergh Method for enhancing glycoprotein stability
US6858598B1 (en) * 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
PE20071042A1 (es) 2005-11-04 2007-10-12 Wyeth Corp Producto farmaceutico que comprende temsirolimus y malato de sunitinib
US20080025946A1 (en) 2006-07-13 2008-01-31 Sivakumar Pallavur V Interleukin 21 and tyrosine kinase inhibitor combination therapy
CN111518218A (zh) * 2006-11-02 2020-08-11 阿塞勒隆制药公司 Alk1受体和配体拮抗剂及其用途
US20090017019A1 (en) * 2007-06-01 2009-01-15 Wyeth Methods and compositions for modulating bmp-10 activity
ES2554812T3 (es) * 2007-11-09 2015-12-23 Genentech, Inc. Composiciones de antagonistas de quinasa 1 de tipo receptor de activina y métodos de uso
KR20100135910A (ko) 2008-04-16 2010-12-27 낫코 파마 리미티드 수니티닙 염기의 신규한 다형 형태
KR20190128254A (ko) * 2008-05-02 2019-11-15 악셀레론 파마 인코포레이티드 혈관신생 및 혈관주위세포 적용범위의 조정을 위한 alk1 길항제 기재의 방법 및 조성물
US7998973B2 (en) 2009-11-13 2011-08-16 Aveo Pharmaceuticals, Inc. Tivozanib and temsirolimus in combination
JP2013523843A (ja) * 2010-04-15 2013-06-17 ベジェニクス ピーティーワイ リミテッド Vegf−c拮抗剤を用いた併用治療

Similar Documents

Publication Publication Date Title
Jiang et al. cGAS-STING, an important pathway in cancer immunotherapy
JP7858715B2 (ja) 高親和性のアイソフォーム選択的TGFβ1阻害剤、およびその使用
Peters et al. Addressing CPI resistance in NSCLC: targeting TAM receptors to modulate the tumor microenvironment and future prospects
Lu et al. Combined PD-1 blockade and GITR triggering induce a potent antitumor immunity in murine cancer models and synergizes with chemotherapeutic drugs
Procaccio et al. Immunotherapy in gastrointestinal cancers
Harris et al. Immuno-oncology combinations: raising the tail of the survival curve
Stern et al. 5T4 oncofoetal antigen: an attractive target for immune intervention in cancer
Tartour et al. Lung cancer: potential targets for immunotherapy
CY1124791T1 (el) Μορια δεσμευσης ειδικα για cd73 και χρησεις αυτων
JP2018515474A5 (enExample)
JP2016539096A5 (enExample)
JP2021512914A5 (enExample)
RU2014134923A (ru) Антагонисты alk1 и их применение в лечении почечно-клеточного рака
Sun et al. Immunotherapy in human colorectal cancer: challenges and prospective
JP2016187356A5 (enExample)
MX2021002190A (es) Estrategia de dosificacion que mitiga el sindrome de liberacion de citoquinas para los anticuerpos biespecificos cd3/cd20.
JP2018501197A5 (enExample)
JP2016532693A5 (enExample)
Duarte et al. Gastric cancer: basic aspects
JP2017506217A5 (enExample)
PH12012502193A1 (en) Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies
WO2006038027A3 (en) SINGLE DOMAIN ANTIBODIES AGAINST TNFRl AND METHODS OF USE THEREFOR
WO2016191643A4 (en) Tigit-binding agents and uses thereof
JP2016537383A5 (enExample)
EP2579895A4 (en) ANTI-VEGF ANTIBODIES AND USES THEREOF