RU2633638C2 - Антагонисты alk1 и их применение в лечении почечно-клеточной карциномы - Google Patents

Антагонисты alk1 и их применение в лечении почечно-клеточной карциномы Download PDF

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RU2633638C2
RU2633638C2 RU2014134923A RU2014134923A RU2633638C2 RU 2633638 C2 RU2633638 C2 RU 2633638C2 RU 2014134923 A RU2014134923 A RU 2014134923A RU 2014134923 A RU2014134923 A RU 2014134923A RU 2633638 C2 RU2633638 C2 RU 2633638C2
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alk1
present
pac
antibody
aspects
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RU2014134923A
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Рупал С. БХАТТ
Равиндра Кумар
Джеймс В. МАЙЕР
Роберт ПИРСОЛЛ
Мэттью ШЕРМАН
Николас СОЛБАН
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Акселерон Фарма Инк.
Бет Израиль Диконесс Медикал Сентр
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RU2014134923A 2012-02-02 2013-02-01 Антагонисты alk1 и их применение в лечении почечно-клеточной карциномы RU2633638C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261593864P 2012-02-02 2012-02-02
US61/593,864 2012-02-02
US201261597124P 2012-02-09 2012-02-09
US61/597,124 2012-02-09
PCT/US2013/024510 WO2013116781A1 (en) 2012-02-02 2013-02-01 Alk1 antagonists and their uses in treating renal cell carcinoma

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RU2014134923A RU2014134923A (ru) 2016-03-27
RU2633638C2 true RU2633638C2 (ru) 2017-10-16

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EP (1) EP2809335A4 (enExample)
JP (1) JP2015506961A (enExample)
KR (1) KR20140123558A (enExample)
CN (1) CN104321070A (enExample)
AU (1) AU2013214779A1 (enExample)
BR (1) BR112014019151A2 (enExample)
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MX (1) MX2014009277A (enExample)
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US10059756B2 (en) 2006-11-02 2018-08-28 Acceleron Pharma Inc. Compositions comprising ALK1-ECD protein
MX2009004718A (es) 2006-11-02 2009-06-19 Acceleron Pharma Inc Antagonistas de receptor de alk1 y ligando y sus usos.
US8642031B2 (en) 2006-11-02 2014-02-04 Acceleron Pharma, Inc. Antagonists of BMP9, BMP10, ALK1 and other ALK1 ligands, and uses thereof
CA2944335A1 (en) * 2014-03-28 2015-10-01 Acceleron Pharma, Inc. Use of activin receptor-like kinase 1 (alk-1) antagonists in the treatment of cancer
JP2016036322A (ja) * 2014-08-11 2016-03-22 日本化薬株式会社 血管新生因子と結合するキメラタンパク質
EP3268025B1 (en) * 2015-03-10 2020-05-06 University of Massachusetts Targeting gdf6 and bmp signaling for anti-melanoma therapy
EP3303387A2 (en) 2015-06-05 2018-04-11 Novartis AG Antibodies targeting bone morphogenetic protein 9 (bmp9) and methods therefor
CN106994181A (zh) * 2017-03-10 2017-08-01 上海交通大学医学院附属第九人民医院 Bmp9在制备延缓肝纤维化药物中的应用
MX2019014023A (es) 2017-05-24 2020-02-17 Novartis Ag Proteinas de anticuerpo injertadas con citocina y metodos de uso en el tratamiento del cancer.
WO2019173482A1 (en) * 2018-03-06 2019-09-12 Sanford Burnham Prebys Medical Discovery Institute 4-aminoquinoline compounds for the treatment of angiogenesis
CN121127500A (zh) 2023-04-07 2025-12-12 达科纳治疗有限公司 针对激活素a受体样1型(alk1)的双特异性激动性抗体

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MX2014009277A (es) 2015-03-03
RU2014134923A (ru) 2016-03-27
WO2013116781A1 (en) 2013-08-08
EP2809335A1 (en) 2014-12-10
EP2809335A4 (en) 2015-10-28
JP2015506961A (ja) 2015-03-05
CN104321070A (zh) 2015-01-28
BR112014019151A2 (pt) 2017-06-27
US20130202594A1 (en) 2013-08-08
KR20140123558A (ko) 2014-10-22
CA2863188A1 (en) 2013-08-08

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