JP2015505244A5 - - Google Patents

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Publication number
JP2015505244A5
JP2015505244A5 JP2014549503A JP2014549503A JP2015505244A5 JP 2015505244 A5 JP2015505244 A5 JP 2015505244A5 JP 2014549503 A JP2014549503 A JP 2014549503A JP 2014549503 A JP2014549503 A JP 2014549503A JP 2015505244 A5 JP2015505244 A5 JP 2015505244A5
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JP
Japan
Prior art keywords
antibody
amino acid
peptide
antigen
acid sequence
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Application number
JP2014549503A
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English (en)
Japanese (ja)
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JP6242808B2 (ja
JP2015505244A (ja
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Priority claimed from PCT/EP2013/050024 external-priority patent/WO2013098419A1/en
Publication of JP2015505244A publication Critical patent/JP2015505244A/ja
Publication of JP2015505244A5 publication Critical patent/JP2015505244A5/ja
Application granted granted Critical
Publication of JP6242808B2 publication Critical patent/JP6242808B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2014549503A 2011-12-28 2013-01-02 所望の特異性を有するモノクローナル自己抗体を提供する方法 Expired - Fee Related JP6242808B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161580837P 2011-12-28 2011-12-28
US61/580,837 2011-12-28
EP11195952.4 2011-12-28
EP11195952 2011-12-28
PCT/EP2013/050024 WO2013098419A1 (en) 2011-12-28 2013-01-02 Method of providing monoclonal auto-antibodies with desired specificity

Publications (3)

Publication Number Publication Date
JP2015505244A JP2015505244A (ja) 2015-02-19
JP2015505244A5 true JP2015505244A5 (enExample) 2016-01-21
JP6242808B2 JP6242808B2 (ja) 2017-12-06

Family

ID=48696366

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014549503A Expired - Fee Related JP6242808B2 (ja) 2011-12-28 2013-01-02 所望の特異性を有するモノクローナル自己抗体を提供する方法

Country Status (12)

Country Link
US (2) US9475872B2 (enExample)
EP (3) EP2797952B1 (enExample)
JP (1) JP6242808B2 (enExample)
AU (3) AU2013206789B2 (enExample)
CA (2) CA2861793C (enExample)
DK (1) DK2797951T3 (enExample)
ES (2) ES2668104T3 (enExample)
HU (1) HUE037186T2 (enExample)
PL (2) PL2797952T3 (enExample)
PT (1) PT2797951T (enExample)
SI (1) SI2797952T1 (enExample)
WO (2) WO2013098419A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10131709B2 (en) 2011-12-28 2018-11-20 Immunoqure Ag Nucleic acid molecules encoding monoclonal antibodies specific for IL-22
EP2626367A1 (en) * 2012-02-10 2013-08-14 Commissariat A L'energie Atomique Et Aux Energies Alternatives Method for obtaining three-dimensional actin structures and uses thereof
US20140199319A1 (en) * 2012-12-14 2014-07-17 Abbvie, Inc. Methods for increasing the efficiency of hybridoma generation
CA2916895C (en) 2013-07-03 2022-08-09 Immunoqure Ag Human anti-il-32 antibodies
US10112995B2 (en) 2013-07-03 2018-10-30 Immunoqure Ag Human anti-IFN-α antibodies
WO2015001047A1 (en) 2013-07-03 2015-01-08 Immunoqure Ag Method of providing anti-human cytokine antibodies for pharmaceutical use
EP2863231A1 (en) * 2013-10-17 2015-04-22 Institut D'Investigaciones Biomédiques August Pi i Sunyer Diagnostic method for detecting a GABA(A) related autoimmune disease and related subject-matter
AU2015282844A1 (en) * 2014-07-03 2016-12-15 Immunoqure Ag Human-derived anti-human IL-20 antibodies and assay for the identification of anti-cytokine antibodies
KR102525734B1 (ko) * 2014-11-07 2023-04-27 후지쿠라 가세이 가부시키가이샤 데옥시하이푸신·신타제 유전자를 지표로서 사용하는 동맥 경화 및 암의 검출 방법
EP3277321B1 (en) 2015-04-01 2024-08-14 AnaptysBio, Inc. Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3)
RU2745898C2 (ru) 2015-04-15 2021-04-02 Анаптисбайо, Инк. Антитела, направленные против рецептора интерлейкина 36 (il-36r)
CN108350071A (zh) * 2015-08-17 2018-07-31 德国神经退行性疾病中心 结合到抗N-甲基-D-天冬氨酸(NMDA)受体抗体的结合区的抗体或抗体片段或非Ig支架
FR3050535B1 (fr) 2016-04-25 2020-11-13 Hospices Civils Lyon Anticorps anti il17
WO2018017996A1 (en) * 2016-07-22 2018-01-25 University Of Washington Identification and production of high affinity igm antibodies and derivatives thereof
SG11201903867YA (en) 2016-11-01 2019-05-30 Anaptysbio Inc Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3)
JP7118073B2 (ja) 2017-01-09 2022-08-15 テサロ, インコーポレイテッド 抗tim-3抗体を用いてがんを処置する方法
US11619832B2 (en) 2018-03-08 2023-04-04 Coopervision International Limited Identification of contact lens wearers predisposed to contact lens discomfort
JP2022516964A (ja) 2019-01-07 2022-03-03 シャタック ラボ,インコーポレイテッド ガンマデルタt細胞を調節するためのヘテロ二量体タンパク質
US11098093B2 (en) 2019-01-07 2021-08-24 Shattuck Labs, Inc. Heterodimeric proteins for modulating gamma delta T cells
WO2021250323A1 (en) * 2020-06-09 2021-12-16 Helsingin Yliopisto Anti-cox-2 autoantibody as a diagnostic marker, and methods, kits and uses related thereto
JP2024509971A (ja) 2021-03-11 2024-03-05 アイジェニックス, インコーポレイテッド アレルギー応答を予測するための方法およびシステム
WO2023213400A1 (en) * 2022-05-05 2023-11-09 Institute For Research In Biomedicine Antibodies against chemokines, method for identifying said antibodies and uses thereof
CN115724983B (zh) * 2022-10-10 2023-09-19 宝船生物医药科技(上海)有限公司 一种针对抗csf1r单克隆抗体的抗独特型抗体及其应用
TW202540204A (zh) 2024-01-26 2025-10-16 西班牙商阿爾米雷爾有限公司 雙特異性分子及使用其的治療方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
AU612370B2 (en) 1987-05-21 1991-07-11 Micromet Ag Targeted multifunctional proteins
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
AU631545B2 (en) 1988-04-15 1992-12-03 Protein Design Labs, Inc. Il-2 receptor-specific chimeric antibodies
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
ES2284161T3 (es) 1990-01-12 2007-11-01 Amgen Fremont Inc. Generacion de anticuerpos xenogenicos.
GB9020282D0 (en) 1990-09-17 1990-10-31 Gorman Scott D Altered antibodies and their preparation
DK9091D0 (da) 1991-01-18 1991-01-18 Novo Nordisk As Fremgangsmaade til fremstilling af antistoffer
DE4130786A1 (de) * 1991-09-16 1993-03-18 Symbiotec Gmbh Peptide zur herstellung von mitteln zur diagnose und therapie von systemischen lupus
JP2006008694A (ja) * 1991-09-16 2006-01-12 Symbiotec Ges Zur Forschung & Entwicklung Au F Dem Gebiet Der Biotechnologie Mbh 全身性エリテマトーデスの診断、治療製剤製造用ペプチド
JP3949712B2 (ja) 1991-12-02 2007-07-25 メディカル リサーチ カウンシル 抗体セグメントレパートリー由来でファージに表示される抗自己抗体の産生
ES2301158T3 (es) 1992-07-24 2008-06-16 Amgen Fremont Inc. Produccion de anticuerpos xenogenicos.
EP0903408A3 (en) 1992-08-21 2005-11-02 Biogen, Inc. Tat-derived transport polypeptide
US6309636B1 (en) * 1995-09-14 2001-10-30 Cancer Research Institute Of Contra Costa Recombinant peptides derived from the Mc3 anti-BA46 antibody, methods of use thereof, and methods of humanizing antibody peptides
EP0822830B1 (en) 1995-04-27 2008-04-02 Amgen Fremont Inc. Human anti-IL-8 antibodies, derived from immunized xenomice
WO1996034096A1 (en) 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP0776906A3 (de) * 1995-10-19 1998-02-25 Imtec Immundiagnostika Gmbh Peptide des Antigens Sm-D und ihre Verwendung, insbesondere für die Diagnostik des SLE
US6590079B2 (en) 1997-01-30 2003-07-08 Ixsys, Incorporated Anti-αvβ3 recombinant human antibodies, nucleic acids encoding same
FI973762A0 (fi) 1997-09-23 1997-09-23 Krohn Kai Ny gen
US6939545B2 (en) 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
US6531580B1 (en) 1999-06-24 2003-03-11 Ixsys, Inc. Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same
US6849425B1 (en) 1999-10-14 2005-02-01 Ixsys, Inc. Methods of optimizing antibody variable region binding affinity
US6838250B2 (en) 2000-03-31 2005-01-04 Ortho-Clinical Diagnostics, Inc. Immunoassay for C-reactive protein
US7638604B2 (en) * 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
US20030044870A1 (en) 2001-07-13 2003-03-06 Peter Sehr Generic capture elisa using recombinant fusion proteins for detecting antibodies in biological samples
JP4489582B2 (ja) * 2002-05-28 2010-06-23 オムリクス・バイオフアーマシユーチカルズ・インコーポレーテツド 抗イディオタイプ抗体を得る方法
US20040101909A1 (en) 2002-08-20 2004-05-27 Hema-Quebec, 2535 Boul. Laurier, Ste-Foy, Quebec, Canada G1V 4M3 Purification of polyreactive autoantibodies and uses thereof
AU2004215125B2 (en) 2003-02-26 2011-01-06 Institute For Research In Biomedicine Monoclonal antibody production by EBV transformation of B cells
GB0407315D0 (en) 2003-07-15 2004-05-05 Cambridge Antibody Tech Human antibody molecules
US7158410B2 (en) 2004-08-27 2007-01-02 Micron Technology, Inc. Integrated DRAM-NVRAM multi-level memory
PL1974020T3 (pl) 2005-12-16 2011-11-30 Ribovax Biotechnologies Sa Sposoby uzyskiwania unieśmiertelnionych komórek wydzielających przeciwciała
WO2007106769A2 (en) * 2006-03-10 2007-09-20 Zymogenetics, Inc. Antibodies that bind both il-17a and il-17f and methods of using the same
TW200815469A (en) 2006-06-23 2008-04-01 Astrazeneca Ab Compounds
JP4059404B2 (ja) * 2006-09-22 2008-03-12 栄研化学株式会社 甲状腺機能を刺激する活性を持つ抗体
PT2099826E (pt) 2007-01-05 2014-01-09 Univ Zuerich Anticorpo anti-beta-amilóide e suas utilizações
ES2523194T3 (es) 2007-03-13 2014-11-21 University Of Zurich Anticuerpo monoclonal humano específico para cada tumor
KR101671452B1 (ko) * 2007-10-25 2016-11-17 트렐리스 바이오싸이언스 인코포레이티드 항rsv g 단백질 항체
GB0807413D0 (en) * 2008-04-23 2008-05-28 Ucb Pharma Sa Biological products
CA2721713C (en) * 2008-05-05 2019-07-09 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
WO2010003529A1 (en) 2008-06-16 2010-01-14 University Of Zurich Method of providing immunoglobulin secreting b lymphocytes and human antibodies
WO2010069603A1 (en) 2008-12-19 2010-06-24 Neurimmune Therapeutics Ag Human anti-alpha-synuclein autoantibodies
EP2427203B1 (en) * 2009-05-05 2018-10-17 Novimmune S.A. Anti-il-17f antibodies and use thereof
EP2258727A1 (en) 2009-05-27 2010-12-08 Wezen Biopharmaceuticals S.r.l. A Socio Unico Immunoglobulin preparation for the treatment of autoimmune diseases and immune system disorders

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