JP2015505244A5 - - Google Patents
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- JP2015505244A5 JP2015505244A5 JP2014549503A JP2014549503A JP2015505244A5 JP 2015505244 A5 JP2015505244 A5 JP 2015505244A5 JP 2014549503 A JP2014549503 A JP 2014549503A JP 2014549503 A JP2014549503 A JP 2014549503A JP 2015505244 A5 JP2015505244 A5 JP 2015505244A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- amino acid
- peptide
- antigen
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161580837P | 2011-12-28 | 2011-12-28 | |
| US61/580,837 | 2011-12-28 | ||
| EP11195952.4 | 2011-12-28 | ||
| EP11195952 | 2011-12-28 | ||
| PCT/EP2013/050024 WO2013098419A1 (en) | 2011-12-28 | 2013-01-02 | Method of providing monoclonal auto-antibodies with desired specificity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015505244A JP2015505244A (ja) | 2015-02-19 |
| JP2015505244A5 true JP2015505244A5 (enExample) | 2016-01-21 |
| JP6242808B2 JP6242808B2 (ja) | 2017-12-06 |
Family
ID=48696366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014549503A Expired - Fee Related JP6242808B2 (ja) | 2011-12-28 | 2013-01-02 | 所望の特異性を有するモノクローナル自己抗体を提供する方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9475872B2 (enExample) |
| EP (3) | EP2797952B1 (enExample) |
| JP (1) | JP6242808B2 (enExample) |
| AU (3) | AU2013206789B2 (enExample) |
| CA (2) | CA2861793C (enExample) |
| DK (1) | DK2797951T3 (enExample) |
| ES (2) | ES2668104T3 (enExample) |
| HU (1) | HUE037186T2 (enExample) |
| PL (2) | PL2797952T3 (enExample) |
| PT (1) | PT2797951T (enExample) |
| SI (1) | SI2797952T1 (enExample) |
| WO (2) | WO2013098419A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10131709B2 (en) | 2011-12-28 | 2018-11-20 | Immunoqure Ag | Nucleic acid molecules encoding monoclonal antibodies specific for IL-22 |
| EP2626367A1 (en) * | 2012-02-10 | 2013-08-14 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Method for obtaining three-dimensional actin structures and uses thereof |
| US20140199319A1 (en) * | 2012-12-14 | 2014-07-17 | Abbvie, Inc. | Methods for increasing the efficiency of hybridoma generation |
| CA2916895C (en) | 2013-07-03 | 2022-08-09 | Immunoqure Ag | Human anti-il-32 antibodies |
| US10112995B2 (en) | 2013-07-03 | 2018-10-30 | Immunoqure Ag | Human anti-IFN-α antibodies |
| WO2015001047A1 (en) | 2013-07-03 | 2015-01-08 | Immunoqure Ag | Method of providing anti-human cytokine antibodies for pharmaceutical use |
| EP2863231A1 (en) * | 2013-10-17 | 2015-04-22 | Institut D'Investigaciones Biomédiques August Pi i Sunyer | Diagnostic method for detecting a GABA(A) related autoimmune disease and related subject-matter |
| AU2015282844A1 (en) * | 2014-07-03 | 2016-12-15 | Immunoqure Ag | Human-derived anti-human IL-20 antibodies and assay for the identification of anti-cytokine antibodies |
| KR102525734B1 (ko) * | 2014-11-07 | 2023-04-27 | 후지쿠라 가세이 가부시키가이샤 | 데옥시하이푸신·신타제 유전자를 지표로서 사용하는 동맥 경화 및 암의 검출 방법 |
| EP3277321B1 (en) | 2015-04-01 | 2024-08-14 | AnaptysBio, Inc. | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| RU2745898C2 (ru) | 2015-04-15 | 2021-04-02 | Анаптисбайо, Инк. | Антитела, направленные против рецептора интерлейкина 36 (il-36r) |
| CN108350071A (zh) * | 2015-08-17 | 2018-07-31 | 德国神经退行性疾病中心 | 结合到抗N-甲基-D-天冬氨酸(NMDA)受体抗体的结合区的抗体或抗体片段或非Ig支架 |
| FR3050535B1 (fr) | 2016-04-25 | 2020-11-13 | Hospices Civils Lyon | Anticorps anti il17 |
| WO2018017996A1 (en) * | 2016-07-22 | 2018-01-25 | University Of Washington | Identification and production of high affinity igm antibodies and derivatives thereof |
| SG11201903867YA (en) | 2016-11-01 | 2019-05-30 | Anaptysbio Inc | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| JP7118073B2 (ja) | 2017-01-09 | 2022-08-15 | テサロ, インコーポレイテッド | 抗tim-3抗体を用いてがんを処置する方法 |
| US11619832B2 (en) | 2018-03-08 | 2023-04-04 | Coopervision International Limited | Identification of contact lens wearers predisposed to contact lens discomfort |
| JP2022516964A (ja) | 2019-01-07 | 2022-03-03 | シャタック ラボ,インコーポレイテッド | ガンマデルタt細胞を調節するためのヘテロ二量体タンパク質 |
| US11098093B2 (en) | 2019-01-07 | 2021-08-24 | Shattuck Labs, Inc. | Heterodimeric proteins for modulating gamma delta T cells |
| WO2021250323A1 (en) * | 2020-06-09 | 2021-12-16 | Helsingin Yliopisto | Anti-cox-2 autoantibody as a diagnostic marker, and methods, kits and uses related thereto |
| JP2024509971A (ja) | 2021-03-11 | 2024-03-05 | アイジェニックス, インコーポレイテッド | アレルギー応答を予測するための方法およびシステム |
| WO2023213400A1 (en) * | 2022-05-05 | 2023-11-09 | Institute For Research In Biomedicine | Antibodies against chemokines, method for identifying said antibodies and uses thereof |
| CN115724983B (zh) * | 2022-10-10 | 2023-09-19 | 宝船生物医药科技(上海)有限公司 | 一种针对抗csf1r单克隆抗体的抗独特型抗体及其应用 |
| TW202540204A (zh) | 2024-01-26 | 2025-10-16 | 西班牙商阿爾米雷爾有限公司 | 雙特異性分子及使用其的治療方法 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| AU612370B2 (en) | 1987-05-21 | 1991-07-11 | Micromet Ag | Targeted multifunctional proteins |
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| AU631545B2 (en) | 1988-04-15 | 1992-12-03 | Protein Design Labs, Inc. | Il-2 receptor-specific chimeric antibodies |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| ES2284161T3 (es) | 1990-01-12 | 2007-11-01 | Amgen Fremont Inc. | Generacion de anticuerpos xenogenicos. |
| GB9020282D0 (en) | 1990-09-17 | 1990-10-31 | Gorman Scott D | Altered antibodies and their preparation |
| DK9091D0 (da) | 1991-01-18 | 1991-01-18 | Novo Nordisk As | Fremgangsmaade til fremstilling af antistoffer |
| DE4130786A1 (de) * | 1991-09-16 | 1993-03-18 | Symbiotec Gmbh | Peptide zur herstellung von mitteln zur diagnose und therapie von systemischen lupus |
| JP2006008694A (ja) * | 1991-09-16 | 2006-01-12 | Symbiotec Ges Zur Forschung & Entwicklung Au F Dem Gebiet Der Biotechnologie Mbh | 全身性エリテマトーデスの診断、治療製剤製造用ペプチド |
| JP3949712B2 (ja) | 1991-12-02 | 2007-07-25 | メディカル リサーチ カウンシル | 抗体セグメントレパートリー由来でファージに表示される抗自己抗体の産生 |
| ES2301158T3 (es) | 1992-07-24 | 2008-06-16 | Amgen Fremont Inc. | Produccion de anticuerpos xenogenicos. |
| EP0903408A3 (en) | 1992-08-21 | 2005-11-02 | Biogen, Inc. | Tat-derived transport polypeptide |
| US6309636B1 (en) * | 1995-09-14 | 2001-10-30 | Cancer Research Institute Of Contra Costa | Recombinant peptides derived from the Mc3 anti-BA46 antibody, methods of use thereof, and methods of humanizing antibody peptides |
| EP0822830B1 (en) | 1995-04-27 | 2008-04-02 | Amgen Fremont Inc. | Human anti-IL-8 antibodies, derived from immunized xenomice |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| EP0776906A3 (de) * | 1995-10-19 | 1998-02-25 | Imtec Immundiagnostika Gmbh | Peptide des Antigens Sm-D und ihre Verwendung, insbesondere für die Diagnostik des SLE |
| US6590079B2 (en) | 1997-01-30 | 2003-07-08 | Ixsys, Incorporated | Anti-αvβ3 recombinant human antibodies, nucleic acids encoding same |
| FI973762A0 (fi) | 1997-09-23 | 1997-09-23 | Krohn Kai | Ny gen |
| US6939545B2 (en) | 1999-04-28 | 2005-09-06 | Genetics Institute, Llc | Composition and method for treating inflammatory disorders |
| US6531580B1 (en) | 1999-06-24 | 2003-03-11 | Ixsys, Inc. | Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same |
| US6849425B1 (en) | 1999-10-14 | 2005-02-01 | Ixsys, Inc. | Methods of optimizing antibody variable region binding affinity |
| US6838250B2 (en) | 2000-03-31 | 2005-01-04 | Ortho-Clinical Diagnostics, Inc. | Immunoassay for C-reactive protein |
| US7638604B2 (en) * | 2001-02-23 | 2009-12-29 | Genetics Institute, Llc | Monoclonal antibodies against interleukin-22 |
| US20030044870A1 (en) | 2001-07-13 | 2003-03-06 | Peter Sehr | Generic capture elisa using recombinant fusion proteins for detecting antibodies in biological samples |
| JP4489582B2 (ja) * | 2002-05-28 | 2010-06-23 | オムリクス・バイオフアーマシユーチカルズ・インコーポレーテツド | 抗イディオタイプ抗体を得る方法 |
| US20040101909A1 (en) | 2002-08-20 | 2004-05-27 | Hema-Quebec, 2535 Boul. Laurier, Ste-Foy, Quebec, Canada G1V 4M3 | Purification of polyreactive autoantibodies and uses thereof |
| AU2004215125B2 (en) | 2003-02-26 | 2011-01-06 | Institute For Research In Biomedicine | Monoclonal antibody production by EBV transformation of B cells |
| GB0407315D0 (en) | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
| US7158410B2 (en) | 2004-08-27 | 2007-01-02 | Micron Technology, Inc. | Integrated DRAM-NVRAM multi-level memory |
| PL1974020T3 (pl) | 2005-12-16 | 2011-11-30 | Ribovax Biotechnologies Sa | Sposoby uzyskiwania unieśmiertelnionych komórek wydzielających przeciwciała |
| WO2007106769A2 (en) * | 2006-03-10 | 2007-09-20 | Zymogenetics, Inc. | Antibodies that bind both il-17a and il-17f and methods of using the same |
| TW200815469A (en) | 2006-06-23 | 2008-04-01 | Astrazeneca Ab | Compounds |
| JP4059404B2 (ja) * | 2006-09-22 | 2008-03-12 | 栄研化学株式会社 | 甲状腺機能を刺激する活性を持つ抗体 |
| PT2099826E (pt) | 2007-01-05 | 2014-01-09 | Univ Zuerich | Anticorpo anti-beta-amilóide e suas utilizações |
| ES2523194T3 (es) | 2007-03-13 | 2014-11-21 | University Of Zurich | Anticuerpo monoclonal humano específico para cada tumor |
| KR101671452B1 (ko) * | 2007-10-25 | 2016-11-17 | 트렐리스 바이오싸이언스 인코포레이티드 | 항rsv g 단백질 항체 |
| GB0807413D0 (en) * | 2008-04-23 | 2008-05-28 | Ucb Pharma Sa | Biological products |
| CA2721713C (en) * | 2008-05-05 | 2019-07-09 | Novimmune Sa | Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof |
| WO2010003529A1 (en) | 2008-06-16 | 2010-01-14 | University Of Zurich | Method of providing immunoglobulin secreting b lymphocytes and human antibodies |
| WO2010069603A1 (en) | 2008-12-19 | 2010-06-24 | Neurimmune Therapeutics Ag | Human anti-alpha-synuclein autoantibodies |
| EP2427203B1 (en) * | 2009-05-05 | 2018-10-17 | Novimmune S.A. | Anti-il-17f antibodies and use thereof |
| EP2258727A1 (en) | 2009-05-27 | 2010-12-08 | Wezen Biopharmaceuticals S.r.l. A Socio Unico | Immunoglobulin preparation for the treatment of autoimmune diseases and immune system disorders |
-
2013
- 2013-01-02 EP EP13700013.9A patent/EP2797952B1/en active Active
- 2013-01-02 CA CA2861793A patent/CA2861793C/en active Active
- 2013-01-02 US US14/369,467 patent/US9475872B2/en not_active Expired - Fee Related
- 2013-01-02 EP EP19159201.3A patent/EP3546481B1/en active Active
- 2013-01-02 DK DK13700002.2T patent/DK2797951T3/en active
- 2013-01-02 WO PCT/EP2013/050024 patent/WO2013098419A1/en not_active Ceased
- 2013-01-02 PL PL13700013T patent/PL2797952T3/pl unknown
- 2013-01-02 PT PT137000022T patent/PT2797951T/pt unknown
- 2013-01-02 AU AU2013206789A patent/AU2013206789B2/en not_active Ceased
- 2013-01-02 US US14/368,749 patent/US9957319B2/en active Active
- 2013-01-02 PL PL13700002T patent/PL2797951T3/pl unknown
- 2013-01-02 HU HUE13700002A patent/HUE037186T2/hu unknown
- 2013-01-02 ES ES13700002.2T patent/ES2668104T3/es active Active
- 2013-01-02 EP EP13700002.2A patent/EP2797951B1/en active Active
- 2013-01-02 AU AU2013206788A patent/AU2013206788B2/en not_active Ceased
- 2013-01-02 CA CA2861695A patent/CA2861695C/en active Active
- 2013-01-02 JP JP2014549503A patent/JP6242808B2/ja not_active Expired - Fee Related
- 2013-01-02 WO PCT/EP2013/050026 patent/WO2013098420A1/en not_active Ceased
- 2013-01-02 ES ES19159201T patent/ES2964168T3/es active Active
- 2013-01-02 SI SI201331457T patent/SI2797952T1/sl unknown
-
2017
- 2017-06-29 AU AU2017204449A patent/AU2017204449A1/en not_active Abandoned
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